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CAS NUMBER: 25322-68-3
EC NUMBER: 500-038-2
MOLECULAR FORMULA: (C₂H₄O)nH₂O
DESCRIPTION:
Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol.
Polyethylene glycol 400 is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.
Polyethylene glycol 400 is water-soluble, nonionic, relatively inert, liquids or solids.
Polymer chains are hydroxyl-terminated at both ends.
Polyethylene glycol 400 has a broad molecular weight distribution ranging from ~ 0.5x to 1.5x the values shown.
Because Polyethylene glycol 400 is hydrophilic molecule, it is used to passivate microscope glass slides to prevent non-specific adhesion of proteins in single-molecule fluorescence studies.
Polyethylene glycol 400 is low in toxicity and is used in a variety of products.
Polyethylene glycol 400 is used as a lubricating coating for a variety of surfaces in aqueous and non-aqueous environments.
Because Polyethylene glycol 400 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures.
Polyethylene glycol 400 is widely used as a polar stationary phase for gas chromatography as well as a heat transfer fluid in electronic test equipment.
Polyethylene glycol 400 is often used in mass spectrometry experiments with its characteristic fragmentation pattern that allows for accurate and reproducible tuning.
Polyethylene glycol 400 derivatives such as narrow-range ethoxylates are used as surfactants.
Polyethylene glycol 400 has been used as the hydrophilic block of amphiphilic block copolymers used to form some polymers.
Polyethylene glycol 400 is the basis of a number of laxatives.
Whole bowel irrigation with polyethylene glycol and additional electrolytes is used for bowel preparation prior to surgery or colonoscopy.
Polyethylene glycol 400 is also used as an excipient in many pharmaceutical products.
When bound to various protein drugs, Polyethylene glycol 400 allows the transported protein to be slowed in the blood.
Polyethylene glycol 400 is commonly used as a crowding agent in in vitro experiments to mimic highly populated cellular conditions.
Polyethylene glycol 400 is commonly used as a precipitate for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of proteins.
Polyethylene glycol 400 is used to fuse two different types of cells, mostly B-cells and myelomas, to form hybridomas.
Polymer fragments derived from Polyethylene glycol 400 polyols add flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam pillows.
Polyethylene glycol 400 precipitation is used to concentrate viruses.
Gene therapy vectors (such as viruses) are coated with Polyethylene glycol 400 to protect them from inactivation by the immune system, and can remove them from organs and prevent them from being targeted where they can exert toxic effects.
Dimethyl ethers of Polyethylene glycol 400 are the key component of Selexol, a solvent used by coal combustion, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream.
Polyethylene glycol 400 has been used as a gate insulator in an electric double layer transistor to induce superconductivity in an insulator.
Polyethylene glycol 400 is also used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the world are researching solid polymer electrolytes containing Polyethylene glycol 400 to improve their properties and allow other products to be used in batteries, electrochromic display systems and other products. future.
Polyethylene glycol 400 is injected into industrial processes to reduce foaming in separation equipment.
Polyethylene glycol 400 is used as a binder in the preparation of technical ceramics.
Polyethylene glycol 400 is the basis of many skin creams (as cetomacrogol) and personal lubricants (often combined with glycerin).
Polyethylene glycol 400 is used as a dispersant in a number of toothpastes.
In this application, Polyethylene glycol 400 binds water and helps keep the xanthan gum evenly distributed throughout the toothpaste.
Polyethylene glycol 400 is also being researched in body armor and tattoos used to monitor diabetes.
Polyethylene glycol 400 belongs to the group of polyoxyethylene glycols.
Polyethylene glycol 400 is a colourless liquid, well soluble in water.
Polyethylene glycol 400 is characterized by strong hygroscopic properties.
Polyethylene glycol 400 exhibits excellent dissolution capacity of the active ingredients.
Polyethylene glycol 400 is characterized by a wide range of applications.
Polyethylene glycol 400 has excellent softening, lubricating, solubilizing, moisturizing and anti-electrostatic properties.
Polyethylene glycol 400 is a polyether compound derived from petroleum with many applications from industrial production to pharmaceuticals.
Polyethylene glycol 400 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE) depending on its molecular weight.
The Polyethylene glycol 400 structure is usually expressed as H−(O−CH2−CH2) n−OH.
Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.
Polyethylene glycol 400 is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Polyethylene glycol 400 is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye.
Polyethylene glycol 400 indicates that the average molecular weight of the specific PEG is 400.
Polyethylene glycol 400 is a clear liquid with an average molecular weight of 400.
Polyethylene glycol 400 is soluble in water and other polar organic solvents.
Polyethylene glycol 400 is useful in a wide variety of applications including lubricants, plastics, paper, pharmaceuticals, personal care, and food industries.
Polyethylene glycol 400 is useful as a viscosity modifier, plasticizer, and heat transfer agent in many industrial applications.
Because it its humectant properties, Polyethylene glycol 400 can be used in many personal care formulations for ointments and creams.
Polyethylene glycol 400 is also used in gelatin capsules as liquid carriers.
Because of Polyethylene glycol 400’s hydroxyl groups, it can also be used as a chemical intermediate.
The low-molecular weight liquid Polyethylene glycol 400 is an excellent solvent for a large number of substances that do not readily dissolve in water.
They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations.
Polyethylene glycol 400 is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power.
Polyethylene glycol 400 is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointment and suppository base, and tablet and capsule lubricant.
Polyethylene glycol 400 has low toxicity with absorption into the body less than 0.5%.
Polyethylene glycol 400 is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable.
Polyethylene glycol 400 is completely soluble in water and has an average molecular weight of 380 - 420.
Polyethylene glycol 400 is another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.
Polyethylene glycol 400 is a high quality research product used as multipurpose polymer of ethelyne glycol for various biochemical, molecular biology and molecular diagnostic applications.
Polyethylene glycol 400 is a polyether compound with many applications from industrial manufacturing to medicine.
Applications of Polyethylene glycol 400 include uses in cosmetics, personal care products in which it is used as a solvent and humectant.
Polyethylene glycol 400 is used in a wide range of lubricant applications due to their low volatility, solubility in water, and natural lubricity.
They are non-staining to metal parts, textiles, and clothing and can be burned away leaving minimal residue.
CHEMICAL PROPERTIES:
Polyethylene glycol 400 is strongly hydrophilic.
The partition coefficient of PEG 400 between hexane and water is 0.000015 indicating that when Polyethylene glycol 400 is mixed with water and hexane, there are only 15 parts of PEG400 in the hexane layer per 1 million parts of PEG 400 in the water layer.
Polyethylene glycol 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons, and is slightly soluble in aliphatic hydrocarbons.
USES:
-Dust suppressant in powdered detergents
-Solubilizing agent in liquid detergents
-Acts as a base/carrier in silver polish
-Antistat and conditioner in leather and vinyl care
-Lubricant and coating in glass cleaner or anti-fog
-Adhesives
-Antistatic agent and humectant
-Chemical intermediates
-Lubricants
-Inks and dye carrier
-Mold release agent
-Plasticizer
BENEFITS:
-Completely soluble in water
-Molecularly stable and non-volatile
-Excellent hygroscopicity
-Low toxicity
-High lubricity and solvency
PHYSICAL AND CHEMICAL PROPERTIES:
-Boiling point: >200 °C (1013 hPa)
-Density: 1.13 g/cm3 (20 °C)
-Flash point: 138.6 °C
-Ignition temperature: 360 °C DIN 51794
-Melting Point: 5 °C
-pH value: 5 - 7 (100 g/l, H₂O, 20 °C)
-Vapor pressure: <0.1 hPa (20 °C)
-Viscosity kinematic: 97 - 110 mm2/s (20 °C)
SPECIFICATION:
-Density (d 20 °C/ 4 °C): 1.124 - 1.127
-Hydroxyl value: 267 - 295
-Average molecular mass: 380 - 420
-Identity (IR): passes test
PROPERTIES:
-Boiling point: >200 °C (1013 hPa)
-Density: 1.13 g/cm3: (20 °C)
-Flash point: >200 °C
-Melting Point: 5 °C
-pH value: 5 – 7 (100 g/l, H₂O, 20 °C)
-Vapor pressure: < – 0.1 hPa (20 °C)
-Viscosity kinematic: 97 – 110 mm2/s (20 °C)
-Solubility: (20 °C) soluble
ADVANTAGES:
-excellent solvent for active substances,
-strong hygroscopic properties,
-agent with anti-electrostatic and lubricating properties,
-high solubility in water,
-PEG with the highest molecular weight, remaining in the form of a liquid at room temperature,
-approved by the FDA for use as an indirect food additive,
-product not classified according to the CLP / GHS Regulation,
-biodegradable product.
USAGE AREAS:
-Medicine and pharmaceutical industry
-Chemical applications
-biological studies
-Personal care products and toothpastes
-Sectoral uses such as soap and ceramic production
APPLICATION:
-self-curing concretes
-cement mortars
-dye baths
-metalworking
-industrial cleaning
-cosmetics
-agrochemicals
-accessories for packaging
-raw material for the synthesis of esters
STORAGE:
Store below +30°C.
SYNONYMS:
Polyethylene Glycol 200
Polyethylene Glycol
PEG-200
ETHYLENE GLYCOL
Ethane-1,2-diol
1,2-ethanediol
107-21-1
glycol
monoethylene glycol
1,2-Dihydroxyethane
2-hydroxyethanol
Glycol alcohol
Ethylene alcohol
polyethylene glycol
Macrogol
Fridex
Tescol
Ethylene dihydrate
Norkool
Macrogol 400 BPC
Dowtherm SR 1
ethanediol
Zerex
Poly(ethylene glycol)
Ucar 17
Lutrol-9
Polyethylene glycol 200
ethyleneglycol
Aethylenglykol
Ethylenglycol
1,2-Ethandiol
1,2-ethylene glycol
ethylen glycol
ethylene-glycol
Polyethylene glycol 600
146AR
Polyethylene glycol 1000
Lutrol 9
Carbowax 300
PEG 200
1,2-dihydroxy ethane
M.e.g.
Polyethylene Glycol 4000
CHEBI:30742
1, 2-Ethanediol
H(OCH2CH2)nOH
Glycol, ethylene-
Glycol, polyethylene
Glycols, polyethylene
Caswell No. 441
Aethylenglykol [German]
Polyethylene oxide
Carbowax 20
CAS-107-21-1
Polyethylene Glycols
Carbowax 400
Carbowax 1000
CCRIS 3744
Dowtherm 4000
HSDB 5012
Ethylene glycol polymer
NCI-C00920
PEG 3350
EINECS 203-473-3
Ethylene glycol homopolymer
Polyethylene Glycol 6000
EPA Pesticide Chemical Code 042203
1,2-Ethanediol homopolymer
ethyleneglycole
Athylenglykol
ehtylene glycol
etylene glycol
AI3-03050
2-ethanediol
Polyaethylenglykol
Ilexan E
4-vinyl cathecol
Polyaethylenglykole
MEG 100
Solbanon (TN)
1,2-ethane diol
1,2-ethane-diol
ethane-1.2-diol
PEG 1000
PEG 4000
1,2-ethyleneglycol
ethan-1,2-diol
mono-ethylene glycol
Macrogol 400
Mono Ethylene Glycol
Carbowax 1540
1,2-ethylene-glycol
Lutrol E (TN)
Ethylene glycol-[d6]
alpha-Hydro-omega-hydroxypoly(oxyethylene)
polyethylene glycol-400
Macrogol 400 (TN)
Polyethylene oxide (NF)
Polyethylene glycol (NF)
Ethyleneglycol, ReagentPlus
Macrogol 1500 (TN)
Macrogol 4000 (TN)
Macrogol 6000 (TN)
EC 203-473-3
Macrogol ointment (JP17)
Glycol, polyethylene(300)
HO(CH2)2OH
Macrogol 400 (JP17)
Polyethylene Glycol 300 NF
alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
Macrogol 1500 (JP17)
Macrogol 4000 (JP17)
Macrogol 6000 (JP17)
Poly(ethylene glycol) methyl ether
Polyethylene glycol 3350 (USP)
Ethylene glycol, p.a., 99.5%
1,2-ETHANEDIOL (GLYCOL)
poly (ethylene glycol) methyl ether
Ethylene glycol, analytical standard
Ethane-1,2-diol (Ethylene Glycol)
alpha,omega-hydroxypoly(ethylene oxide)
Ethylene glycol, Spectrophotometric grade
Oxirane, 2,2'-((1-methylethylidene)bis(4,1-phenyleneoxymethylene))bis-, polymer with alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
Dihydrocarveol, (-)-, mixture of isomers
ETHYLENE GLYCOL HIGH PURITY GRD 1L
Ethylene glycol
1,2-Ethane-1,1,2,2-d4-diol-d2(9ci)
Ethylene glycol
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-
ethylene glycol1,2-ethanediol
ethane-1,2-diol;
glycolethylene glycol;ethanediol;
ethylene glycol 1,2-ethanediol ethane-1,2-diol glycolethylene glycol ethanediol
