Polyethylene Glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility.
Polyethylene Glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
In gas chromatography, Polyethylene Glycol 8000 is used as a polar stationary phase.
CAS Number: 25322-68-3
EC Number : 500-038-2
MDL number: MFCD00081839
INCI Name: PEG-180
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (180 mol EO average molar ratio)
Food additive: E1521
Classification: PEG/PPG , Ethoxylated compound , Glycol , Synthetic polymer
Chemical Family: Polyethylene Glycols, Polyols
Linear Formula: H(OCH2CH2)nOH
SYNONYMS:
PEG, Poly(ethylene glycol), Polyethyleneglycol 8000, Macrogol 8000, Macrogols 8000, Poly(ethylene glycol), Polyethyleneglycol 8000, PEG 8k, Polyethylene glycol, Poly(ethylene glycol), Polyethylene glycol, polyethylene oxide standard 511000, Poly(ethylene oxide), macrogol, poly(oxyethylene), Polyethylene glycol PEG, Aquacide III, PEG 1000, PEG 6000, MB Grade (1.12033), Ethylene glycol 8000 polymer, Polyethyleneglycol, Polyethylene Glycol 5000000, PolyethyleneoxideMW, PEG 200-8000, Tri-(2,3-Dibromopropyl) Phosphate, Polyethylene glycol - 6000 grade, PEG 200, PEG 400, PEG 6000, Poly(ethylene oxide), PEO, PEG 600, Polyethyleneoxidemonomethacryloxymonotrimethylsiloxyterminated, -Methacryloxy(polyethyleneoxy)trimethylsilane, PEG, Poly ethylene glycol, Carmowax, carbowax, PEG 8000, Polyethylene glycol series, Polyethylene Glycol, Polyethylene glygcol, Polyethylene Glycol 8000, HO-[CH2CH2O]n-H, CAS Number-25322-68-3, Polyethylene Oxide, Carbowax, PEG 8000, Polyethylene Glycol, Macrogol, 25322-68-3, CARBOWAX 8000, CARBOWAX PEG 8000, LIPO POLYGLYCOL 8000, LUMULSE PEG 8000, MACROGOL 8000, PEG 8000, PEG-180, PEG-180 [INCI], POLYETHYLENE GLYCOL 8000 [II], POLYETHYLENE GLYCOL 8000 [USP-RS], POLYETHYLENE GLYCOL 8000 [VANDF], POLYGLYKOL 8000, UPIWAX 8000, Carbowax 8000 PEG Sentry Gran, CARBOWAX™ SENTRY™ POLYETHYLENE GLYCOL 8000 GRANULAR NF, FCC GRADE, MACROGOL 8000 Ph. Eur. Carbowax, PEG, Poly(Ethylene Oxide), Alkapol PEG-8000, Macrogol, α-Hydro-ο-hydroxypoly (oxy-1,2-ethanediyl), PEG, Poly(ethylene glycol), Polyethyleneglycol 8000, Macrogol 8000, Macrogols 8000, PEG, Poly(ethylene glycol), Polyethyleneglycol 8000, Macrogol 8000, Macrogols 8000, PEG 8000, PEG 8k, Polyethylene glycol 8000, PEG 8000, Polyethylene oxide, Carbowax, Macrogol 8000, Poly(oxyethylene), α‑hydro‑ω‑hydroxy‑ethane‑1,2‑diol, PEO, PEG, PEG 600, PEG 200, PEG 400, macrogol, carbowax, PEG 6000, PEG 8000, PEG 1000, Carmowax, alcoxe30, Alcox E 30, Alcox E 160, Aquacide III, PEG 200-8000, poly(oxyethylene), Polyethyleneglycol, Polyethylene glycol, PolyethyleneoxideMW, Polyethylene Glycol, Polyethylene glygcol, Poly(ethylene oxide), Poly ethylene glycol, Poly(ethylene glycol), Polyethylene glycol PEG, Polyethylene glycol series, 1,2-ethanediol,homopolymer, Polyethylene Glycol 5000000, PEG 6000, MB Grade (1.12033), Ethylene glycol 8000 polymer, Polyethylene glycol - 6000 grade, Tri-(2,3-Dibromopropyl) Phosphate, polyethylene oxide standard 511000, Poly(ethylene oxide), approx. M.W. 200,000, Poly(ethylene oxide), approx. M.W. 900,000, Poly(ethylene oxide), approx. M.W. 600,000, O-Methacryloxy(polyethyleneoxy)trimethylsilane, 2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-Poly(oxy-1, Polyethyleneoxidemonomethacryloxymonotrimethylsiloxyterminated
Polyethylene Glycol 8000 is a polyether compound that has wide application ranging from industrial manufacturing and medicine.
Polyethylene Glycol 8000 is generally used in the precipitation of phage.
Ultrapure white crystals for molecular biology applications of Polyethylene Glycol 8000 such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.
Polyethylene Glycol 8000 is white granular.
Polyethylene Glycol 8000 is soluble in water, soluble in some organic solvents.
The solution has high viscosity at low concentration, and can be processed by calendering, extrusion, casting, etc.
Polyethylene Glycol 8000 is a thermoplastic resin with good compatibility with other resins.
Resistant to bacterial erosion, moisture absorption in the atmosphere is weak.
Polyethylene Glycol 8000 is a mixture of ethylene oxide and water polycondensation.
The molecular formula of Polyethylene Glycol 8000 is expressed as ho(ch2ch2o)nh, where n represents the average number of oxyethylene groups.
Polyethylene Glycol 8000 is a polyether compound with many applications from industrial manufacturing to medicine.
Polyethylene Glycol 8000 is a hydrophilic polymer.
Polyethylene Glycol 8000 can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups.
Polyethylene Glycol 8000 is a polymer of ethylene oxide, commonly used in various applications due to its solubility in water.
USES and APPLICATIONS of POLYETHYLENE GLYCOL 8000:
Pharmaceutical / Medical: Polyethylene Glycol 8000 is used as laxative formulations (e.g. MiraLAX, Movicol, Fortrans) especially macrogol 3350–8000 for bowel preparation or constipation relief
Excipient: Polyethylene Glycol 8000 is used tablet lubricant, film coating agent, solvent in oral liquids, cell‑fusion medium, protein/drug PEGylation for improved solubility and bloodstream half‑life
Analytical / Lab: Polyethylene Glycol 8000 is used precipitation of DNA, plasmids, proteins; stationary phase for gas chromatography; standard in mass spectrometry
Industrial uses of Polyethylene Glycol 8000: dispersant in toothpastes; anti‑foaming agent (E1521 in EU food); lubricant and mold‑release in elastomer fabrication; wood stabilization/preservation
Polyethylene Glycol 8000 is used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.
a high molecular weight polymer with diverse applications in cosmetics, food, and pharmaceuticals.
Polyethylene Glycol 8000 can be used in cosmetics/food/drug.
Polyethylene Glycol 8000 (PEG 8000), also known as Macrogol 8000, is a high molecular weight polymer with diverse applications in cosmetics, food, and pharmaceuticals.
Polyethylene Glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility.
Polyethylene Glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
In gas chromatography, Polyethylene Glycol 8000 is used as a polar stationary phase.
Polyethylene Glycol 8000 is used as mold release agent and lubricant in fabricating elastomers.
As a dispersant, Polyethylene Glycol 8000 is used in toothpastes.
Polyethylene Glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
In pharmaceutical industry, Polyethylene Glycol 8000 is used as tablet and capsule lubricant.
Polyethylene Glycol 8000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene Glycol 8000 is often utilized in mass spectrometry experiments and as a polar stationary phase for Gas Chromatorgraphy.
Polyethylene Glycol 8000 is also used to preserve objects that have been retrieved from the ocean.
In fabricating elastomers, Polyethylene Glycol 8000 functions as a lubricant and mold releasing agent.
In pharmaceuticals, Polyethylene Glycol 8000 can function as a tablet and capsule lubricant.
Applications of Polyethylene Glycol 8000: Crystallization grade Polyethylene Glycol 8000 for formulating screens or for optimization.
Polyethylene Glycol 8000 is used as PVC lubricant, masterbatch additive, textile softener, pigment dispersant, etc
Pharmaceuticals: Polyethylene Glycol 8000 is used as an excipient in drug formulations, as a laxative, and in controlled-release medications.
Cosmetics and Personal Care: Polyethylene Glycol 8000 acts as a humectant, thickener, and solvent in lotions, creams, and toothpaste.
Industrial Applications: Polyethylene Glycol 8000 is used as a lubricant, plasticizer, and in various manufacturing processes.
Biotechnology: Polyethylene Glycol 8000 is employed in protein precipitation, cell culture, and other biological applications.
Polyethylene Glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility.
Polyethylene Glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
In gas chromatography, Polyethylene Glycol 8000 is used as a polar stationary phase.
Polyethylene Glycol 8000 is used as mold release agent and lubricant in fabricating elastomers.
As a dispersant, Polyethylene Glycol 8000 is used in toothpastes.
Polyethylene Glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
In pharmaceutical industry, Polyethylene Glycol 8000 is used as tablet and capsule lubricant.
Polyethylene Glycol 8000 is used in the precipitation of phage, isolation of plasmid DNA and the enhancement of blunt-ended ligation reactions.
Polyethylene Glycol 8000 is suitable as a medium for the fusion of mammalian cells.
Polyethylene Glycol 8000 is also used to precipitate bacteriophage from lysed cell supernatants.
Polyethylene Glycol 8000 is a white or almost white solid with a waxy or paraffin-like appearance.
Polyethylene Glycol 8000 is very soluble in water and in methylene chloride, very slightly soluble in alcohol, practically insoluble in fatty oils and in mineral oils.
-Use of Polyethylene Glycol 8000 in Cosmetics:
Polyethylene Glycol 8000 is utilized in various cosmetic and personal care products for several functions:
Humectant:
Polyethylene Glycol 8000 retains moisture in the skin, helping to keep it hydrated and smooth.
Thickening Agent:
Polyethylene Glycol 8000 enhances the viscosity and texture of products such as creams, lotions, and gels.
Emulsifying Agent:
Polyethylene Glycol 8000 helps blend oil and water-based ingredients, creating stable emulsions.
Stabilizer:
Polyethylene Glycol 8000 maintains the consistency and stability of formulations, preventing separation.
Film-Forming Agent:
Polyethylene Glycol 8000 provides a protective layer on the skin, enhancing the product's efficacy.
-Use of Polyethylene Glycol 8000 in Food:
In the food industry, Polyethylene Glycol 8000 is occasionally used for specific purposes:
Antifoaming Agent:
Polyethylene Glycol 8000 prevents and reduces foam during food processing, improving efficiency.
Glazing Agent:
Polyethylene Glycol 8000 provides a shiny finish to food products such as candies and pastries.
Thickener and Stabilizer:
Polyethylene Glycol 8000 enhances the texture and stability of various processed foods, contributing to a consistent quality.
-Use of Polyethylene Glycol 8000 in Pharmaceuticals:
Polyethylene Glycol 8000 is widely used in pharmaceuticals due to its beneficial properties:
Laxative:
Polyethylene Glycol 8000 is used in formulations to treat constipation by increasing the water content in the stool, facilitating easier passage.
Excipient:
Polyethylene Glycol 8000 acts as a carrier or medium for active pharmaceutical ingredients, aiding in their delivery and absorption.
Binder:
Polyethylene Glycol 8000 helps in the formation of tablets by binding the ingredients together, ensuring proper dosage and stability.
Solubilizer:
Polyethylene Glycol 8000 improves the solubility of poorly water-soluble drugs, enhancing their bioavailability.
Base for Ointments and Creams:
Polyethylene Glycol 8000 provides a stable and consistent base for topical formulations.
Usage:
Polyethylene Glycol 8000 can be used as a solvent or as a carrier in all kinds of cosmetics.
Mixing method:
Mixed with the substance to be dissolved.
Rate of use:
Depending on use.
-Pharmaceuticals uses of Polyethylene Glycol 8000:
– Laxatives: Polyethylene Glycol 8000 is used as the active ingredient in over-the-counter laxatives.
Polyethylene Glycol 8000 works by retaining water in the stool, which helps to soften it and promote bowel movements.
– Tablet and Capsule Formulation:
Polyethylene Glycol 8000 serves as a binder, lubricant, and coating agent in tablets and capsules, improving their stability and controlling the release of the active ingredients.
– Drug Delivery Systems:
Due to its ability to form hydrogels, Polyethylene Glycol 8000 is used in controlled-release drug delivery systems, allowing for a gradual release of medications.
-Cosmetics and Personal Care uses of Polyethylene Glycol 8000:
– Moisturizers and Lotions:
Polyethylene Glycol 8000 acts as a humectant, attracting and retaining moisture in the skin, which helps to keep it hydrated.
– Toothpaste:
Polyethylene Glycol 8000 is used as a thickening agent to give toothpaste its consistency and to ensure even distribution of the ingredients.
– Hair Care Products:
In shampoos and conditioners, Polyethylene Glycol 8000 provides a smooth, silky texture and helps to stabilize the formulation.
-Food Industry uses of Polyethylene Glycol 8000:
Food Additive:
Polyethylene Glycol 8000 can be used as an anti-foaming agent, a thickener, or a solvent in various food products.
Its usage is regulated, and Polyethylene Glycol 8000 must comply with specific safety guidelines.
Food Packaging:
Polyethylene Glycol 8000 can be incorporated into food packaging materials to improve flexibility and durability.
-Industrial Applications of Polyethylene Glycol 8000:
– Lubricants:
Polyethylene Glycol 8000 is used as a lubricant in various industrial processes, including in machinery and molds, due to its non-reactive and non-corrosive properties.
– Plasticizer:
In the manufacturing of plastics, Polyethylene Glycol 8000 is used as a plasticizer to enhance flexibility and reduce brittleness.
– Adhesives:
Polyethylene Glycol 8000 acts as a stabilizer and thickener in adhesive formulations, improving their performance and application.
-Biotechnology and Research uses of Polyethylene Glycol 8000:
– Protein Precipitation:
In molecular biology, Polyethylene Glycol 8000 is used to precipitate proteins and nucleic acids by reducing their solubility, which helps in purification processes.
– Cell Culture:
Polyethylene Glycol 8000 is used in cell fusion techniques and as a crowding agent in cell culture, promoting more natural cell environments.
– Cryopreservation:
Polyethylene Glycol 8000 helps protect cells, proteins, and other biological materials during freezing, reducing the formation of ice crystals.
-Agriculture uses of Polyethylene Glycol 8000:
– Water Retention:
In agricultural applications, Polyethylene Glycol 8000 can be added to soil to improve water retention, which is beneficial in arid regions.
– Seed Coating:
Polyethylene Glycol 8000 is used in seed coatings to control the release of fertilizers and other nutrients, improving germination rates.
-Medical Devices uses of Polyethylene Glycol 8000:
– Lubricants for Catheters and Tubes:
Polyethylene Glycol 8000 is used as a lubricant for medical devices like catheters, ensuring smooth insertion and reducing discomfort for patients.
– Hydrogels:
Polyethylene Glycol 8000 is used in the production of hydrogels for wound care, providing a moist environment that promotes healing.
These uses highlight the versatility of Polyethylene Glycol 8000 across various fields, making it an essential compound in many industries.
CHARACTERISTICS of POLYETHYLENE GLYCOL 8000:
*Molecular Weight:
Approximately 8,000 Daltons.
*Physical Form:
Usually found as a white powder or flakes.
*Solubility:
Polyethylene Glycol 8000 is soluble in water, alcohols, and many organic solvents.
*Viscosity:
Higher than lower molecular weight PEGs, making Polyethylene Glycol 8000 useful where increased viscosity is needed.
*Safety Guidelines of Polyethylene Glycol 8000:
Polyethylene Glycol 8000 has a wide range of specific uses across different industries.
CHARACTERISTICS of POLYETHYLENE GLYCOL 8000:
Polyethylene Glycol 8000 is a white powder.
*Solubility:
Polyethylene Glycol 8000 is soluble in water, ethanol, glycols (eg propylene glycol, butylene glycol).
*Storage:
Polyethylene Glycol 8000 can be stored at room temperature But close the bottle tightly And sealed from direct sunlight or heat, the product is at least 2 years old.
FEATURES of POLYETHYLENE GLYCOL 8000:
*Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
Polyethylene Glycol 8000 is white, granular product with a mild odor.
Polyethylene Glycol 8000 is miscible with water and provides excellent solvency, lubricity and hygroscopicity in a wide variety of formulations.
Polyethylene Glycol 8000 is used in applications which include ceramics, miniing, wood treatment, powdered detergents and as a fragrance and dye carrier.
BENEFITS of POLYETHYLENE GLYCOL 8000:
*Miscible with water
*Highly versatile
*Excellent solvency
*lubricity and hygroscopicity
*Recommended Use
*Fragrance carrier
*Dye carrier
*Ceramics
*Automotive sprays
*Household cleaners
*Lubricants
*Mining
*Mold release agent
*Plasticizers
*Wood treating
*Powdered detergents
TRAIT of POLYETHYLENE GLYCOL 8000:
Polyethylene Glycol 8000 is a colorless or almost colorless viscous liquid, or a translucent waxy soft object; Slightly odorless.
Polyethylene Glycol 8000 is soluble in water or ethanol, insoluble in ether.
freezing point
The freezing point of Polyethylene Glycol 8000 (General rule 0613) is 33~38°C.
viscosity
take 25.0g of Polyethylene Glycol 8000, put it in a 50ml measuring flask, add water to dissolve it and dilute it to the scale, shake it well, and use a pinch viscometer with a capillary inner diameter of 0.8mm, the kinematic viscosity at 0633 is 401 to 8.5/s when measured according to law.
BENEFITS of POLYETHYLENE GLYCOL 8000:
Polyethylene Glycol 8000 will not support microbial growth, even in aqueous solutions.
Versatile, water-miscible vehicle used as solvent and solubilizing agent for active substances and excipients in liquid and semisolid preparation.
Polyethylene Glycol 8000 can be paired with BASF surfactants (for example Kolliphor® RH 40) to promote solubilization of poorly water-soluble APIs.
Polyethylene Glycol 8000 can be used for crystallization inhibition with BASF polymers (for example Kollidon 12 PF).
Polyethylene Glycol 8000 can also be used as a chemical intermediate in drug formulation.
Wide acceptance in pharmaceutical application for over 50 years.
WHAT IS IT?
Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments and suppository base, and tablet and capsule lubricant.
PEG has low toxicity with systemic absorption less than 0.5%.
PEGylation occurs when PEGs are attached to various protein medications, allowing for greater solubility for certain drugs.
Examples of PEGylated medications include PEG-interferon alpha (Pegintron) and PEG-filgrastim (Neulasta).
PEG is also available as a bowel prep for colonoscopy procedures and as a laxative.
PEG 400 indicates the average molecular weight of the specific PEG at 400.
PEG 3350 is a laxative available over-the-counter by the name of Miralax.
In this case, PEG is considered an "active" ingredient, even though systemic absorption is less than 0.5%.
PHYSICAL and CHEMICAL PROPERTIES of POLYETHYLENE GLYCOL 8000:
Molecular Weight: 7000-9000
Appearance Form: solid
Color: light yellow
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: 57,5 °C
Initial boiling point and boiling range: 205,7 °C at 977,6 hPa
Flash point: 138,6 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 0,01 hPa at 20 °C
Vapor density: No data available
Density: 1,116 g/cm3 at 20 °C at 975,5 hPa
Relative density: No data available
Water solubility: 256,084 g/l at 25 °C
Partition coefficient: n-octanol/water
log Pow: -0,698 at 30 °C - Bioaccumulation is not expected.
Autoignition temperature: 360 °C
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Physical Form: Solid
Average Number of Repeating Oxyethylene Units: 181
Range of Average Molecular Weight: 7000 – 9000
Range of Average Hydroxyl Number, mg KOH/g: 12 – 16
Density, g/cm3 at 70°C: 1.07
Melting or Freezing Range, °C: 55 – 62
Solubility in Water at 20°C, % by weight: 63
Viscosity at 100°C: cSt 500 - 900
Heat of Fusion: Cal/g 41
Color: White
Physical Form: Solid
Boiling Point: 200°C
Molecular Formula: (C2H4O)n
Density: 1.1g/mL
SMILES: [H]OCCO
Molecular Weight (g/mol): 62.07
Flash Point: 270°C
pH: 5.0 to 7.0
CAS: 25322-68-3
Melting Point: 55°C to 60°C
MDL Number: MFCD01779601
InChI Key: LYCAIKOWRPUZTN-UHFFFAOYSA-N
IUPAC Name: ethane-1,2-diol
Formula Weight: 7000 to 9000
Identification: Pass Test
Chemical Name or Material: Carbowax™ PEG 8000
CAS: 25322-68-3
Molecular formula: H(OCH2CH2)nOH
Molecular weight: 7000 - 9000
Appearance: White/colorless powder or flakes
Solubility: Clear solution at 5% in water at 25°C
Melting point: 61 - 64 °C
pH (5%, H2O): 5.5 - 7.0
Water: < 0.5 %
UV data: 260 nm: < 0.099
280 nm: < 0.03
Peroxides (H2O2): < 0.001 %
Chloride: < 50 ppm
Copper: < 5 ppm
Iron: < 5 ppm
Storage: Room Temperature. Protect from moisture.
Stability: Stable at least 2 years at R.T
Linear Formula: H(OCH2CH2)nOH
CAS Number: 25322-68-3
MDL number: MFCD00081839
UNSPSC Code: 41116107
NACRES: NA.24
CAS: 25322-68-3
EINECS: 500-038-2
Molecular Formula: N/A
Density: 1.27 g/mL at 25°C
Melting Point: 64-66°C
Boiling Point: >250°C
Flash Point: 270 °C
Water Solubility: Soluble in water.
Solubility: Slightly hygroscopic. It melts easily when heated.
Soluble in water and ethanol
Vapor Pressure: <0.01 mm Hg (20 °C)
Vapor Density: >1 (vs air)
Appearance: waxy solid
Specific Gravity: 1.128
Color: White to very pale yellow
Maximum wavelength (λmax): ['λ: 260 nm Amax: 0.6', 'λ: 280 nm Amax: 0.3']
Merck: 14,7568
pH: 5.5-7.0 (25℃, 50 mg/mL in H2O)
Storage Condition: 2-8°C
Stability: Stable. Incompatible with strong oxidizing agents.
Sensitive: Hygroscopic
Refractive Index: n20/D 1.469
MDL: MFCD00081839
Physical and Chemical Properties
Density: 1.125
Melting Point: -65°C
Refractive Index: 1.458-1.461
Flash Point: 171°C
Chemical Name: Polyethylene Glycol 8000 (PEG 8000), also called Polyethylene Oxide (PEO), Polyoxyethylene (POE)
CAS Number: 25322-68-3
EINECS/EC Number: 500-038-2
Molecular Formula: H(OCH₂CH₂)_nOH, average molecular weight ~7,000–9,000 g/mol (nominal 8,000)
Appearance: white crystalline powder, waxy pellets or granular solid
Odor: almost odorless or mild characteristic smell
Melting / Freezing Point: ~55–63 °C
Boiling / Decomposition: >200 °C; Flash point ~229–265 °C; Auto-ignition >360 °C
Density / Specific Gravity: ~1.11–1.21 (varies with temperature)
Solubility: water soluble (~63 % at 20 °C)
pH (5 % aqueous solution): 4.5–7.5
Viscosity: ~700–900 cSt at ~99 °C
Vapor Pressure: <0.01 hPa at 20 °C
Stability: stable; may oxidize at high temperature; hazardous polymerization does not occur; avoid oxidizers and strong acids/bases
FIRST AID MEASURES of POLYETHYLENE GLYCOL 8000:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact: rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of POLYETHYLENE GLYCOL 8000:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Take up dry.
Clean up affected area.
FIRE FIGHTING MEASURES of POLYETHYLENE GLYCOL 8000:
-Extinguishing media:
*Suitable extinguishing media:
Water Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.
EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYETHYLENE GLYCOL 8000:
-Control parameters:
Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of POLYETHYLENE GLYCOL 8000:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Stored at room temperature.
But close the lid of the bottle tightly.
The product has a shelf life of at least 2 years.
STABILITY and REACTIVITY of POLYETHYLENE GLYCOL 8000:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions: No data available