PRODUCTS

POLYETHYLENEIMINE (PEI)

Polyethyleneimine (PEI) linear can be used for cell transfection.
Polyethyleneimine (PEI) linear can bind to DNA and other negatively charged biomolecules and is a low-toxic and efficient cell transfection agent.
Polyethyleneimine (PEI) linear can be used for targeted delivery of nucleic acid drugs.

CAS Number: 9002-98-6
EC Number: 205-793-9
MDL number: MFCD00084427
Linear Formula: H(NHCH2CH2)nNH2
Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable

SYNONYMS:
Poly(iminoethylene), Polyaziridine, Poly[imino(1,2-ethanediyl)], MFCD00084427, Aziridine, homopolymer, aziridine, homopolymer, PEI, PEI-10, polyethyleneimine, branched, m.w. 1800, Aziridine,homopolymer, polyethylenimine(10,000), POLYETHYLENEIMINE, BRANCHED, PEI-35, PEI-2500, PEI-1500, polyethylenimine(20,000), Ethyleneimine,homopolymer, Aziridine, Ethylenimine, Azacyclopropane, Everamine, Polymin, Dimethyleneimine, Polyethyleneimine, Dihydroazirene, Dihydroazirine, Polymine P, Aziran, Polymin P, ETHYLENEIMINE, Polymin FL, Ethylene imine, Montrek 6, Ethylenimine resins, Everamine 50T, Poly(ethylenimine), Polyaziridine, p 1000 (polyamine), epamine 150t, epomin sp 110, epomin p 500, epomin p 003, xa 1007, polymin g 15m, poly (ethylenimine), lupasol g 35, pei, polymin fl, pr 20 (release agent), pei 1000, polymin p, k 203c, pei-30, polymin sna, sedipur cl 930, epomin sp 300, pei 18, aziridine,polymers,homopolymer, pei-700, everamine, everamine 210t, pei 100, polyethyleneimine, epomin sp 200, epomin sp 003, dow pei-18, pei-10, montrek 6, epomin p 1500, el 402, polymin g 100, pei-275, lupasol wf, epomin sp 012, ethylenimine, polymers, pei-250, pei-600, epomin sp 1000, epomin d 3000, polymin 6, montrek 1000, everamine 150t, dow pei-6, p 600xe, epomine 150t, dow pei-600e, 15t, lupasol sk, pei 2, epomin sp 018, pei-45, polymin g 35, polymin, epomin sp 006, corcat p 18, pei-7, lugalvan g 15, epomine p 1000, everamine 50t, polymin hs, pei 400, polyethylenimine, m.w.600, pei 600, ethoxylated polyethylenimine, m.w. 60,000, p 0381, epomin 150t, ethylenimine resins, p 1000, 2mb, bufloc 595, pei 1120, polyethyleneimine, 50 % solution in water, lugalvan g 35, pei-14m, corcat p 145, pei-35, pei 12, cf 218 (polymer), corcat p 600, montrek 600, epomine 1000, corcat p 150, epomin p 1000, lugalvan g 20, aziridine homopolymer, montrek 12, emerlube 6717, pei 1, epomin 1000, pei-15, tydex 12, everamine 500t, pei 6, p 100 (polyamine), polymin g 20, corcat p 200, epomin sp 103, lupasol g 20, lupasol fg, p 70 (polyamine), basocoll pr 8086, montrek pei 6, montrek 18, corcat p 12, Polyethylenimine (PEI), corcat p 100, 1/c2h5n/c1-2-3-1/h3h,1-2h, polymin g 500, epomin pp 061, ethylenimine, homopolymer, up 300 (polyamine), adcote 372, lupasol p, el 420, montrek pei 18, ethylenimine polymer, epomin p 1050, paz 33, polymine p, polyethylenimine, m.w.1800, Ethylenimine, polymers, Montrek 1000, PEI 18, Epomin SP 003, Montrek PEI 18, Corcat P 12, Epomin P 500, Montrek PEI 6, XA 1007, Lugalvan G 15, Polyethylenimine, M.W.1800, Polyethylenimine (PEI), Ethylenimine resins, Epomin P 1500, Epomin SP 018, Corcat P 150, Montrek 12, Polymine P, Epomin P 003, P 1000 (polyamine), Ethylenimine, homopolymer, Lupasol WF, Epomin 150T, Polymin HS, EL 420, Dow PEI-600e, Polymin G 20, PAZ 33, Lupasol G 20, Lugalvan G 20, Montrek 6, Everamine 210T, Aziridine homopolymer, Epomin SP 012, UP 300 (polyamine), PEI, P 100 (polyamine), Montrek 18, K 203C, 15T, Epomin P 1000, Epomin SP 1000, Everamine 500T, Polymin P, Tydex 12, 1/C2H5N/c1-2-3-1/h3H,1-2H, Epamine 150T, Corcat P 200, Epomine P 1000, Epomin PP 061, Aziridine,polymers,homopolymer, PEI-600, Adcote 372, PEI 600, PR 20 (release agent), Everamine 50T, Epomin 1000, Epomin SP 006, Polymin 6, Epomin P 1050, Polyethyleneimine, PEI 400, Corcat P 145, PEI 1, PEI 12, Polymin G 100, Basocoll PR 8086, Lupasol G 35, Dow PEI-6, Polymin G 15M, PEI 1000, Ethylenimine polymer, PEI 6, Polyethylenimine, M.W.600, Epomine 1000, Polymin, Epomin SP 200, 2MB, CF 218 (polymer), Everamine, Dow PEI-18, PEI 100, Lupasol SK, Epomin SP 103, P 0381, Lupasol P, Ethoxylated polyethylenimine, M.W. 60,000, Corcat P 600, Epomin D 3000, Polymin G 35, EL 402, Poly (ethylenimine), P 600XE, Epomin SP 110, P 1000, Polymin G 500, Everamine 150T, Lugalvan G 35, PEI 1120, Sedipur CL 930, Epomin SP 300, P 70 (polyamine), Polymin FL, Emerlube 6717, Corcat P 100, PEI 2, Lupasol FG, Epomine 150T, Corcat P 18, Montrek 600, Bufloc 595, Polymin SNA, Polyethyleneimine, 50 % solution in water, epomine 150t, pei-600, polymine p, aziridine,polymers,homopolymer, everamine 50t, polyethyleneimine, lupasol fg, corcat p 145, montrek 12, ethylenimine polymer, p 100 (polyamine), pei-700, corcat p 600, polymin g 35, pei-7, lupasol p, epomin pp 061, corcat p 12, pei-35, epomin p 003, polymin p, pei 400, epomin sp 300, ethylenimine, polymers, up 300 (polyamine), pr 20 (release agent), basocoll pr 8086, 1/c2h5n/c1-2-3-1/h3h,1-2h, montrek 1000, ethylenimine, homopolymer, el 402, lupasol wf, polymin g 20, bufloc 595, pei, ethylenimine resins, aziridine homopolymer, pei 18, el 420, polymin g 100, polymin fl, montrek 18, epomin sp 1000, epomin d 3000, epomin 150t, epomin p 1050, 2mb, everamine 150t, epomin sp 012, pei 12, epomin p 1500, epomin sp 200, p 600xe, dow pei-18, polymin hs, pei 1, sedipur cl 930, polymin sna, polyethylenimine, m.w.1800, pei 6, montrek pei 18, corcat p 100, epomin 1000, epomin p 500, k 203c, corcat p 200, p 0381, everamine 500t, xa 1007, pei-275, p 1000, pei-14m, epomine 1000, pei 1000, lupasol g 20, pei-10, Polyethylenimine (PEI), epomin p 1000, pei 1120, corcat p 150, paz 33, pei-250, epomin sp 103, polyethyleneimine, 50 % solution in water, polymin g 15m, corcat p 18, dow pei-6, lugalvan g 20, polymin 6, ethoxylated polyethylenimine, m.w. 60,000, everamine, lupasol g 35, poly (ethylenimine), 15t, polymin g 500, epomine p 1000, adcote 372, everamine 210t, epomin sp 003, emerlube 6717, polymin, pei 600, pei-45, epomin sp 018, lupasol sk, polyethylenimine, m.w.600, epomin sp 110, pei 2, montrek pei 6, montrek 6, pei 100, pei-15, pei-30, dow pei-600e, lugalvan g 15, montrek 600, epomin sp 006, p 1000 (polyamine), epamine 150t, p 70 (polyamine), cf 218 (polymer), tydex 12, lugalvan g 35, Adcote372MW, Aldrich 408719, Aldrich 482595, Aziridine Polymer, Basocoll PR 8086, Basomin G 500, Basonal White FO 1, Bufloc 595, CF 218, CF 218 (Polymer), CP 8994, Corcat P 100, Corcat P 12, Corcat P 145, Corcat P 150, Corcat P 18, Corcat P 200, Corcat P 600, Duramax 1007, EA 275, EAz 1300, EAz 800, EC 005, EL 402, EL 420, EP 108, EP 108 (Polymer), Emerlube 6717, Epomin, Epomin 018, Epomin 1000, Epomin 1050, Epomin 150T, Epomin D 3000, Epomin HM 2000, Epomin L 18, Epomin P 003, Epomin P 012, Epomin P 1000, Epomin P 1030, Epomin P 1050, Epomin P 1500, Epomin P 200, Epomin P 500, Epomin S 1000, Epomin S 300, Epomin SP 003, Epomin SP 006, Epomin SP 012, Epomin SP 012D, Epomin SP 018, Epomin SP 030, Epomin SP 050, Epomin SP 075, Epomin SP 1000, Epomin SP 103, Epomin SP 110, Epomin SP 12, Epomin SP 200, Epomin SP 300, Ethyleneimine Homopolymer, Ethylenimine Homopolymer, Everamine, Everamine 150T, Everamine 210T, Everamine 500T, Everamine 50T, F 2S, FC, Fluka P 3142, G 100, G 20, G 20WF, G 35, G 500, HF, HG 20, HM 2000, HZ 20, HZ 20 (Polyamine), IP 232, JS 980, K 203C, Katax 6760, L 771, Liposol G, Loxanol MI 6730, Loxanol MI 6735, Lugalvan G 15, Lugalvan G 20, Lugalvan G 35, Lugalvan G 50, Lupasol 800, Lupasol 8515, Lupasol C 20, Lupasol F-WF, Lupasol FC, Lupasol FG, Lupasol FG 800, Lupasol FS, Lupasol G 10, Lupasol G 100, Lupasol G 20, Lupasol G 20WF, Lupasol G 20WFR, Lupasol G 35, Lupasol G 500, Lupasol G20 Waterfree, Polyethylenimine (PEI), Polyethylenimine (PEI) Plus, Polyethylenimine (PEI)+, Lupasol LU 321, Lupasol P, Lupasol P-WF, Lupasol PN 40, Lupasol PR, Lupasol PR 8515, Lupasol PS, Lupasol R, Lupasol SN, Lupasol WF, Lupasoli G, Lupazol, Luposal P, Luprasol SK, Mica A 131X, Montrek 1000, Montrek 12, Montrek 18, Montrek 6, Montrek 600, OEI 800, Oribain EL 420, P 0381, P 100, P 100 (Polyamine), P 1000, P 1030, P 200, P 3142, P 3143, P 600, P 600XE, P 70, P 70 (Polyamine), PC 8994, PEI, PEI 1, PEI 100, PEI 1000, PEI 1120, PEI 12, PEI 18, PEI 2, PEI 300, PEI 400, PEI 6, PEI 600, PEI 700000, PEO 113V, PR 20, PR 20 (Release Agent), PR 8515, Poly 8, Polyaziridine, Polyethenimide, Polyimin P, Polymin 6, Polymin FL, Polymin G 100, Polymin G 15M, Polymin G 20, Polymin G 35, Polymin G 500, Polymin HM, Polymin HS, Polymin PR 9711, Polymin PR 971L, Polymin SKA, Polymin SNA, Polymin WF, Polymin Waterfree, Rewin CLE, Rhenocure DR, SN, SP 003, SP 006, SP 012, SP 012D, SP 018, SP 1050, SP 110, SP 200, SP 300, SP 400, SP 400 (Polyimine), SP 600, Sedipur CL 930, T 13A, TS 280, TS 280 (Crosslinking Agent), Titabond 185E, Titabond T 100, Toyobain 210K, Toyobine 210K, Tydex 12, UN 3082, UP 300, UP 300 (Polyamine), WF, XA 1007, XUS 19036.00, epomine 150t, pei-600, polymine p, aziridine,polymers,homopolymer, everamine 50t, polyethyleneimine, lupasol fg, corcat p 145, montrek 12, ethylenimine polymer, p 100 (polyamine), pei-700, corcat p 600, polymin g 35, pei-7, lupasol p, epomin pp 061, corcat p 12, pei-35, epomin p 003, polymin p, pei 400, epomin sp 300, ethylenimine, polymers, up 300 (polyamine), pr 20 (release agent), basocoll pr 8086, 1/c2h5n/c1-2-3-1/h3h,1-2h, montrek 1000, ethylenimine, homopolymer, el 402, lupasol wf, polymin g 20, bufloc 595, pei, ethylenimine resins, aziridine homopolymer, pei 18, el 420, polymin g 100, polymin fl, montrek 18, epomin sp 1000, epomin d 3000, epomin 150t, epomin p 1050, 2mb, everamine 150t, epomin sp 012, pei 12, epomin p 1500, epomin sp 200, p 600xe, dow pei-18, polymin hs, pei 1, sedipur cl 930, polymin sna, polyethylenimine, m.w.1800, pei 6, montrek pei 18, corcat p 100, epomin 1000, epomin p 500, k 203c, corcat p 200, p 0381, everamine 500t, xa 1007, pei-275, p 1000, pei-14m, epomine 1000, pei 1000, lupasol g 20, pei-10, lupasol hf, epomin p 1000, pei 1120, corcat p 150, paz 33, pei-250, epomin sp 103, polyethyleneimine, 50 % solution in water, polymin g 15m, corcat p 18, dow pei-6, lugalvan g 20, polymin 6, ethoxylated polyethylenimine, m.w. 60,000, everamine, lupasol g 35, poly (ethylenimine), 15t, polymin g 500, epomine p 1000, adcote 372, everamine 210t, epomin sp 003, emerlube 6717, polymin, pei 600, pei-45, epomin sp 018, lupasol sk, polyethylenimine, m.w.600, epomin sp 110, pei 2, montrek pei 6, montrek 6, pei 100, pei-15, pei-30, dow pei-600e, lugalvan g 15, montrek 600, epomin sp 006, p 1000 (polyamine), epamine 150t, p 70 (polyamine), cf 218 (polymer), tydex 12, lugalvan g 35, aziridine, homopolymer, ethylenimine, homopolymer, PEI-1000, poly(ethylenimine),

Polyethyleneimine (PEI) or polyaziridine is a polymer with repeating units composed of the amine group and two carbon aliphatic CH2CH2 spacers.
Linear polyethyleneimines contain all secondary amines, in contrast to branched PEIs which contain primary, secondary and tertiary amino groups.

Totally branched, dendrimeric forms were also reported.
Polyethyleneimine (PEI) is produced on an industrial scale and finds many applications usually derived from its polycationic character.
Polyethyleneimine (PEI) is a water-soluble polymer made by the polymerization of ethyleneimine.

Polyethyleneimine (PEI) is not an entirely linear polymer; it has a highly-branched structure that contains primary, secondary, and tertiary amines.
Polyethyleneimine (PEI), an organic polyamine polymer, is one of the most prominent examples of cationic polymers capable of gene transfection in vitro and in vivo into various cell lines and tissues.

Polyethyleneimine (PEI) was also applied in different fields from gene therapy and several studies have emphasized the importance of this polymer in medicinal chemistry.
Polyethyleneimine (PEI) is a clear viscous liquid.

USES and APPLICATIONS of POLYETHYLENEIMINE (PEI):
Polyethyleneimine (PEI) can also be used to make materials in hot environments like hot tape, hot cables, hot pipes, etc.
In addition, Polyethyleneimine (PEI) can also be used to manufacture high-strength fibers, high-performance composite materials and so on.
In summary, Polyethyleneimine (PEI) is an excellent polymer material that can be used in a wide range of applications.

Polyethyleneimine (PEI) has the characteristics of water proofing, heat insulation, and freshness, which makes PEI widely used in many fields such as construction, power, chemical industry, and medical treatment.
It is believed that with the development of materials science, the role and application field of Polyethyleneimine (PEI) will continue to expand.

Polyethyleneimine (PEI), a cationic polymer, has revolutionized the field of transfection with its exceptional efficiency and adaptability.
Polyethyleneimine (PEI)'s unique capability to create stable complexes with nucleic acids enables the effective transfer of DNA, RNA, and proteins into various cell types, including those historically challenging to transfect.

A significant advantage of Polyethyleneimine (PEI) lies in its superior transfection efficiency, surpassing many conventional methods.
Polyethyleneimine (PEI)'s capacity to surmount cellular barriers and directly deliver genetic material to the nucleus ensures robust and dependable gene expression, catering to a wide spectrum of research needs spanning from fundamental inquiries to therapeutic interventions.

Moreover, Polyethyleneimine (PEI) provides researchers with extensive flexibility in experimental design, allowing for precise adjustments of transfection parameters to achieve optimal outcomes.
This versatility empowers scientists to explore diverse avenues in gene function studies, protein expression analyses, and gene therapy investigations, unleashing new possibilities in molecular biology and genetic research.

Polyethyleneimine (PEI) is used, among other things, as a precipitant for the preparation of cell extracts.
Due to its charge, Polyethyleneimine (PEI) primarily precipitates highly negatively charged nucleic acids, but potentially also strongly acidic proteins (which have many negative charges in the form of carboxylate groups R–COO − on their surface).

Polyethyleneimine (PEI) can therefore be used to classify nucleic acids and proteins, especially because nucleic acids may interfere with other protein purification methods.
High-molecular-weight Polyethyleneimine (PEI) is used in paper production as a flocculant and retention agent.

Polyethyleneimine (PEI) can also be used as an ion exchanger in water treatment.
Further applications include the transfection of nucleic acids, such as plasmids or siRNAs, into human or murine cells, both for in vivo and in vitro transfections.

The use of Polyethyleneimine (PEI) also represents a cost-effective alternative to commercial transfection reagents.
Polyethyleneimine (PEI) is a hydrophilic cationic polymer that can be used as a gene carrier and has high transfection efficiency.
Polyethyleneimine (PEI) linear can be used to improve the chemical properties of negatively charged dyes and is often used as an adhesion promoter with a similar function to polylysine.

Polyethyleneimine (PEI) linear attracts the influx of chloride and subsequently penetrates water into the lysosomes when the lysosomes are protonated, causing lysosome rupture and releasing the nucleic acid into the cytoplasm.
The molecular weight of this Polyethyleneimine (PEI) linear product is 10kDa.

Polyethyleneimine (PEI), cas number 9002-98-6, is an important synthetic polymer material with a variety of special properties and a wide range of applications.
Polyethyleneimine (PEI) is a linear polymer that is synthesized from ethylene imide monomer by polymerization.

Polyethyleneimine (PEI) has high molecular weight, high branching, abundant amine groups, etc., which makes it have a wide application prospect in the field of electronics, opto-electronics, and aviation.
Polyethyleneimine (PEI) is a polymer with good solubility that dissolves in a variety of solvents.
Polyethyleneimine (PEI) has a high solubility in water and can form a stable colloidal solution with water.

This dissolution property makes Polyethyleneimine (PEI) have good processability and controllability, and can be prepared by solution method, thermoforming, spraying and other methods of different shapes and sizes of materials.
Polyethyleneimine (PEI) finds many applications in products like: detergents, adhesives, water treatment agents and cosmetics.

Owing to its ability to modify the surface of cellulose fibres, Polyethyleneimine (PEI) is employed as a wet-strength agent in the paper-making process.
Polyethyleneimine (PEI) is also used as flocculating agent with silica sols and as a chelating agent with the ability to complex metal ions such as zinc and zirconium.

Main Applications of Polyethyleneimine (PEI): Laminate anchor coating agents for paper, cloth, OPP and PET film, Heavy metal chelating agents, Metal plating additives, Foam retainers for fire extinguishers, Immobilized enzymes, Adhesives (for PVC sol flocculants, Epoxy resin crosslinkers), Ink adhesion enhancer, Water treatment (as coagulants)

Both linear and branched Polyethyleneimine (PEI) have been used for CO2 capture, frequently impregnated over porous materials.
First use of Polyethyleneimine (PEI) polymer in CO2 capture was devoted to improve the CO2 removal in space craft applications, impregnated over a polymeric matrix.

After that, the support was changed to MCM-41, an hexagonal mesostructured silica, and large amounts of Polyethyleneimine (PEI) were retained in the so-called "molecular basket".
MCM-41-PEI adsorbent materials led to higher CO2 adsorption capacities than bulk Polyethyleneimine (PEI) or MCM-41 material individually considered.

The authors claim that, in this case, a synergic effect takes place due to the high Polyethyleneimine (PEI) dispersion inside the pore structure of the material.
As a result of this improvement, further works were developed to study more in depth the behaviour of these materials.

Exhaustive works have been focused on the CO2 adsorption capacity as well as the CO2/O2 and CO2/N2 adsorption selectivity of several MCM-41-PEI materials with Polyethyleneimine (PEI) polymers.
Also, Polyethyleneimine (PEI) impregnation has been tested over different supports such as a glass fiber matrix and monoliths.

However, for an appropriate performance under real conditions in post-combustion capture (mild temperatures between 45-75 °C and the presence of moisture), it is necessary to use thermally and hydrothermally stable silica materials, such as SBA-15, which also presents an hexagonal mesostructure.
Moisture and real world conditions have also been tested when using Polyethyleneimine (PEI)-impregnated materials to adsorb CO2 from the air.

A detailed comparison among Polyethyleneimine (PEI) and other amino-containing molecules showed an excellent performance of PEI-containing samples with cycles.
Also, only a slight decrease was registered in their CO2 uptake when increasing the temperature from 25 to 100 °C, demonstrating a high contribution of chemisorption to the adsorption capacity of these solids.

For the same reason, the adsorption capacity under diluted CO2 was up to 90% of the value under pure CO2 and also, a high unwanted selectivity towards SO2 was observed.
Lately, many efforts have been made in order to improve Polyethyleneimine (PEI) diffusion within the porous structure of the support used.

A better dispersion of Polyethyleneimine (PEI) and a higher CO2 efficiency (CO2/NH molar ratio) were achieved by impregnating a template-occluded PE-MCM-41 material rather than perfect cylindrical pores of a calcined material, following a previously described route.
The combined use of organosilanes such as aminopropyl-trimethoxysilane, AP, and Polyethyleneimine (PEI) has also been studied.

The first approach used a combination of them to impregnate porous supports, achieving faster CO2-adsorption kinetics and higher stability during reutilization cycles, but no higher efficiencies.
A novel method is the so-called "double-functionalization".
It is based on the impregnation of materials previously functionalized by grafting (covalent bonding of organosilanes).

Amino groups incorporated by both paths have shown synergic effects, achieving high CO2 uptakes up to 235 mg CO2/g (5.34 mmol CO2/g).
CO2 adsorption kinetics were also studied for these materials, showing similar adsorption rates as impregnated solids.
This is an interesting finding, taking into account the smaller pore volume available in double-functionalized materials.

Thus, Polyethyleneimine (PEI) can be also concluded that their higher CO2 uptake and efficiency compared to impregnated solids can be ascribed to a synergic effect of the amino groups incorporated by two methods (grafting and impregnation) rather than to a faster adsorption kinetics.
Polyethyleneimine (PEI) and poly(ethylenimine) ethoxylated (PEIE) have been shown as effective low-work function modifiers for organic electronics by Zhou and Kippelen et al.

Polyethyleneimine (PEI) could universally reduce the work function of metals, metal oxides, conducting polymers and graphene, and so on.
It is very important that low-work function solution-processed conducting polymer could be produced by the Polyethyleneimine (PEI) or PEIE modification.

Based on this discovery, Polyethyleneimine (PEI) is been widely used for organic solar cells, organic light-emitting diodes, organic field-effect transistors, perovskite solar cells, perovskite light-emitting diodes, quantum-dot solar cells and light-emitting diodes etc.
Polyethyleneimine (PEI) can be used as a non-viral synthetic polymer carrier for in vivo delivery of therapeutic nucleic acids.

The interaction between the negatively charged nucleic acid and the positively charged polymer backbone leads to the formation of nanoscale complexes.
This neutralising complex protects the enclosed nucleic acid from enzymes and maintains its stability until cellular uptake occurs.
For example, human serum albumin-coupled Polyethyleneimine (PEI) shows good pDNA transfection and low toxicity.

Polyethyleneimine (PEI) can be used to functionalize single-walled nanotubes (SWNTs) to improve their solubility and biocompatibility while maintaining the structural integrity of the original SWNT.
Covalently functionalized SWNTs can be used for CO2 uptake and gene delivery.
Branched Polyethyleneimine (PEI) can also be used to modify the surface properties of adsorbents.

Polyethyleneimine (PEI)-modified aqueous zirconia/PAN nanofibres have a high fluoride adsorption capacity and a wide working pH range, and can therefore be used for groundwater defluoridation.
Polyethyleneimine (PEI) acts as a protein precipitant used to purify proteins.
Polyethyleneimine (PEI) is used as a chelating agent and as a scavenger for aldehydes and oxides.

Polyethyleneimine (PEI) is also used in detergents, paper industry, dyes, printing inks and in water treatment.
Branched Polyethyleneimine (PEI) is widely used in many applications due to its polycationic character.
Unlike its linear equivalent, branched Polyethyleneimine (PEI) contains primary, secondary, and tertiary amines.

Primarily utilized in industrial applications, high molecular weight Polyethyleneimine (PEI) has been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture.
Polyethyleneimine (PEI) is used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.

Polyethyleneimine (PEI) is used detergents, adhesives, water treatment, printing inks, dyes, cosmetics, and paper industry, adhesion promoter, lamination primer, fixative agent, flocculant, cationic dispersant, stability enhancer, surface activator, chelating agent, scavenger for aldehydes and oxides.

-Use of Polyethyleneimine (PEI) in delivery of HIV-gene therapies:
Polyethylenimine (PEI), a cationic polymer, has been widely studied and shown great promise as an efficient gene delivery vehicle.
Likewise, the HIV-1 Tat peptide, a cell-permeable peptide, has been successfully used for intracellular gene delivery.

-Aerospace uses of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) has excellent physical properties such as light weight, high strength and high temperature resistance, so it is widely used in the aerospace field.
For example, Polyethyleneimine (PEI) can be used as thermal insulation material, thermal conductivity material, protective material, etc.

-Medical field uses of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) has excellent biocompatibility and high temperature resistance, so it is widely used in the medical field.
For example, Polyethyleneimine (PEI) can be used as medical dressings, surgical instruments, medical packaging materials, etc.

-Electronics use of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) is an excellent insulating material with excellent electrical insulation properties and high temperature resistance.
Therefore, Polyethyleneimine (PEI) is widely used in the insulation layer of electronic components, circuit boards, cables and other fields.
In the semiconductor manufacturing process, Polyethyleneimine (PEI) is also used as a thin film substrate for the manufacture of high-density integrated circuits.

-Photoelectric field uses of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) has excellent transparency and high temperature resistance, so it is widely used in the field of photoelectricity.
For example, Polyethyleneimine (PEI) can be used as a substrate material for solar panels, and it can also be used to make LED packaging materials.

-Biology uses of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) has a number of uses in laboratory biology, especially tissue culture, but is also toxic to cells if used in excess.
Toxicity is by two different mechanisms, the disruption of the cell membrane leading to necrotic cell death (immediate) and disruption of the mitochondrial membrane after internalisation leading to apoptosis (delayed).

-Attachment promoter uses of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) is used in the cell culture of weakly anchoring cells to increase attachment.
Polyethyleneimine (PEI) is a cationic polymer; the negatively charged outer surfaces of cells are attracted to dishes coated in PEI, facilitating stronger attachments between the cells and the plate.

-Transfection reagent ues of Polyethyleneimine (PEI):
Polyethyleneimine (PEI) was the second polymeric transfection agent discovered, after poly-L-lysine.
Polyethyleneimine (PEI) condenses DNA into positively charged particles, which bind to anionic cell surface residues and are brought into the cell via endocytosis.

Once inside the cell, protonation of the amines results in an influx of counter-ions and a lowering of the osmotic potential.
Osmotic swelling results and bursts the vesicle releasing the polymer-DNA complex (polyplex) into the cytoplasm.

If the polyplex unpacks then the DNA is free to diffuse to the nucleus.
Permeabilization of gram negative bacteria
Polyethyleneimine (PEI) is also an effective permeabilizer of the outer membrane of Gram-negative bacteria

CHARACTERISTICS of POLYETHYLENEIMINE (PEI):
*Waterproof:
POLYETHYLENEIMINE has good waterproof performance, which can effectively prevent water penetration and leakage.

*Heat insulation:
Polyethyleneimine (PEI) has good heat insulation performance and can effectively prevent the transfer of heat energy.

*Freshness:
Polyethyleneimine (PEI) has strong airtight performance, which can effectively maintain the freshness of food and other items and extend the shelf life.

*Corrosion resistance:
Polyethyleneimine (PEI) has high corrosion resistance and is able to resist the attack of certain chemicals.

*High strength:
Polyethyleneimine (PEI) has high strength and is able to effectively resist pull, pull, squeeze and other forces.

PROPERTIES of POLYETHYLENEIMINE (PEI):
The linear Polyethyleneimine (PEI) is a semi-crystalline solid at room temperature while branched PEI is a fully amorphous polymer existing as a liquid at all molecular weights.
Linear polyethyleneimine is soluble in hot water, at low pH, in methanol, ethanol, or chloroform.

Polyethyleneimine (PEI) is insoluble in cold water, benzene, ethyl ether, and acetone.
Linear Polyethyleneimine (PEI) has a melting point of around 67 °C.
Both linear and branched polyethylneimine can be stored at room temperature.
Linear Polyethyleneimine (PEI) is able to form cryogels upon freezing and subsequent thawing of its aqueous solutions.

SYNTHESIS of POLYETHYLENEIMINE (PEI):
Branched Polyethyleneimine (PEI) can be synthesized by the ring opening polymerization of aziridine.
Depending on the reaction conditions different degree of branching can be achieved.

Linear Polyethyleneimine (PEI) is available by post-modification of other polymers like poly(2-oxazolines) or N-substituted polyaziridines.
Linear Polyethyleneimine (PEI) was synthesised by the hydrolysis of poly(2-ethyl-2-oxazoline) and sold as jetPEI.
The current generation in-vivo-jet Polyethyleneimine (PEI) uses bespoke poly(2-ethyl-2-oxazoline) polymers as precursors.

FEATURES of POLYETHYLENEIMINE (PEI):
Polyethyleneimine (PEI) is the highest cation-dense polymer in existence.
Polyethyleneimine (PEI) is a very high reactive polymer.
Polyethyleneimine (PEI) is a water-soluble polymer.

PRODUCTION METHODS of POLYETHYLENEIMINE (PEI):
Polyethyleneimine (PEI) is produced by the homopolymerization of ethylenimine.
The reaction is catalyzed by acids, Lewisacids, or haloalkanes.
The polymerization is usually carried out at 90 – 110 ℃ in water or in a variety of organic solvents.

The average molecular mass of the Polyethyleneimine (PEI) prepared as described above is 10 000 – 20 000.
Higher molecular mass polymers are prepared by addition of a difunctional alkylating agent, such as chloromethyloxirane or 1,2-dichloroethane.
Polyethyleneimine (PEI) with a higher average molecular mass can also be provided by ultrafiltration of polymers with a broad mass distribution.

Likewise, polymers of lower molecular mass can be obtained by inclusion of a low molecular mass amine, such as 1,2- ethanediamine, during polymerization.
By using these techniques a range of molecular masses from 300 to 10⁶ can be obtained.

Cross-linking during the polymerization of ethylenimine in organic solvents leads to solid Polyethyleneimine (PEI).
Furthermore the polymerization process can be conducted on the surface of organic or inorganic materials, thus fixing the Polyethyleneimine (PEI) to a support.

FEATURES AND PROPERTIES of POLYETHYLENEIMINE (PEI):
***High adhesion and absorption
The amino group forms hydrogen bonds with hydroxyl group, ionic bonds with carboxyl group, and covalent bonds with the aldehyde group and ketone group.

Polyethyleneimine (PEI) also has polar group (amino group) and hydrophobic group (ethylene group) in its structure, which and enhances its bonding force with materials of different polarities.
These comprehensive bonding forces of Polyethyleneimine (PEI)are utilized in fields such as adhesion, ink, paint, and pressure-sensitive adhesive agents.

***High cationicity
Polyethyleneimine (PEI) exists as polycation in water, and it neutralizes and adsorbs all types of anionic materials.
Polyethyleneimine (PEI) also chelates heavy metal ions.

This highly cationic property of Polyethyleneimine (PEI) is utilized in fields such as paper manufacturing, water treatment, plating bath agents, dispersants, etc.

***Highly Reactive
Because of its reactive primary and secondary amino group, Polyethyleneimine (PEI) easily reacts with epoxy, aldehyde, isocyanate compounds, and acid gases.

This highly reactive property of Polyethyleneimine (PEI) is utilized in the modification of epoxy resins, aldehyde adsorbents and dye-fixing agents.
Polyethyleneimine (PEI) is a branched chain polymer having a ratio of 1:2:1 of primary:secondary:tertiary amines with a branching site every 3–3.5 nitrogen atoms and a general backbone of (CH2CH2NH)x.

Polyethyleneimine (PEI) has a cationic charge when the nitrogen atoms are protonated, so the charge density is pH dependent.
There is essentially no active monomer present.
Polyethyleneimine (PEI) is a efficient polymeric transfection reagent, compatible for a wide range of cell lines and/or cell types including the most commonly used cells, such as HEK293 and CHO, grown in adherent and suspension cultures.

Polyethyleneimine (PEI) is supplied as a 50% (w/v) aqueous solution.
Polyethyleneimine (PEI) is formally the polymer of aziridine, also known as ethyleneimine.
Both Polyethyleneimine (PEI) and the polymer are secondary amines, not imines.

MOLECULAR STRUCTURE of POLYETHYLENEIMINE (PEI):
However, when ethyleneimine is polymerized by ring-opening polymerization, a highly branched polymer molecule is formed.
The amino groups are protonated upon addition of water, and thus it exists as a strongly basic polycation in aqueous solution.
Polyethyleneimine (PEI) is formally the polymer of aziridine, also known as ethyleneimine.

Both the monomer and Polyethyleneimine (PEI) are secondary amines, not imines.
However, when ethyleneimine is polymerized by ring-opening polymerization, a highly branched polymer molecule is formed.
The amino groups are protonated upon addition of water, and thus it exists as a strongly basic polycation in aqueous solution.

PHYSICAL and CHEMICAL PROPERTIES of POLYETHYLENEIMINE (PEI):
Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable
Melting Point: 59-60°C
Boiling Point: 250 °C(lit.)
Flash Point: >230 °F
Molecular Formula: C2H5N
Molecular Weight: 43.06780

Density: 1.030 g/mL at 25 °C
Physical state: viscous
Color: colorless
Odor: No data available
Melting point/freezing point
Melting point/range: 54 - 59 °C
Initial boiling point and boiling range: 250 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point: > 110 °C - closed cup
Autoignition temperature: > 200 °C
Decomposition temperature: > 250 °C
pH: 11 - DIN 19268
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 15.000 mPa.s at 50 °C
Water solubility soluble
Partition coefficient: n-octanol/water: No data available

Vapor pressure: No data available
Density: 1,030 g/cm3 at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Fòrmula: (C2H5N)x
No. CAS: 9002-98-6
Appearance: Liquid
Color: Colorless to light yellow
SMILES: NCCN(CCN)CCN(CCCNCN)CCN(CCNCCN)CCNCCN(CCN)CCN.[n]
Appearance (Form): Viscous Liquid
Refractive index: n20/D 1.5290
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C

Impurities: ≤1% water
CBNumber: CB9162514
Molecular Formula:C2H5N
Molecular Weight:43.07
MDL Number:MFCD00803910
MOL File:9002-98-6.mol
Melting point: 59-60°C
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C

vapor pressure: 9 mmHg ( 20 °C)
refractive index: n20/D 1.5290
Flash point: >230 °F
storage temp.: 2-8°C
solubility: DMSO (Sparingly)
form: Liquid
color: Pale yellow
Specific Gravity: 1.045 (20/4℃)

PH: pH(50g/l, 25℃) : 10～12
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
InChI: InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChIKey: NOWKCMXCCJGMRR-UHFFFAOYSA-N
SMILES: C1NC1
LogP: -0.969 (est)
Indirect Additives used in Food Contact Substances: POLYETHYLENIMINE

EWG's Food Scores: 1
EPA Substance Registry System: Aziridine, homopolymer (9002-98-6)
IUPAC Name: aziridine
Molecular Weight: 10,000
Molecular Formula: C2H5N
Canonical SMILES: C1CN1
InChI Key: NOWKCMXCCJGMRR-UHFFFAOYSA-N
Density: 1.029-1.038
EC Number: 205-793-9

Exact Mass: 43.04220
H-Bond Acceptor: 1
H-Bond Donor: 1
UN Number: 1185
Viscosity: 40,000 - 150,000 cps
Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable
Density: 1.030 g/mL at 25 °C
Boiling Point: 250 °C(lit.)

Flash Point: >230 ºF
Melting Point: 59-60 °C
Refractive index: n20D 1.5290
CAS No.: 9002-98-6
Molecular Formula: (C2H5N)x
InChIKeys: InChIKey=NOWKCMXCCJGMRR-UHFFFAOYSA-N
Molecular Weight: 43.069
Exact Mass: 43.04220

EC Number: 205-793-9
HScode: 39019090
Categories: Polymer
PSA: 21.94000
XLogP3: -0.4
Appearance: Pale yellow Liquid
Density: 1.05 g/cm3
Melting Point: 59-60°C

Boiling Point: 250 °C(lit.)
Flash Point: >230 °F
Refractive Index: n20/D 1.5290
Water Solubility: soluble in water.
Storage Conditions: 2-8°C
Vapor Pressure: 9 mmHg ( 20 °C)
Vapor Density: 1.48

Flammability characteristics: Class IB
Explosive limit: Explosive limits , vol% in air: 3.3-55
Odor: Pungent, ammonia-like odor
PH: Strongly alkaline
Name: Polyethyleneimine
EINECS: 205-793-9
CAS No.: 9002-98-6
Density: 1.030 g/mL at 25 °C

PSA: 21.94000
LogP: -0.08160
Solubility: Soluble in water.
Melting Point: 59-60°C
Formula: (C2H5N)x
Boiling Point: 250 °C(lit.)
Molecular Weight: 43.06780
Flash Point: >230 °F
Appearance: N/A

Assay:95.00 to 100.00
Food Chemicals Codex Listed:No
Boiling Point:57.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:221.311996 mmHg @ 25.00 °C. (est)
Flash Point:-38.00 °F. TCC ( -39.00 °C. ) (est)
logP (o/w):-0.969 (est)
Soluble in:water, 1e+006 mg/L @ 25 °C (est)

FIRST AID MEASURES of POLYETHYLENEIMINE (PEI):
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of POLYETHYLENEIMINE (PEI):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of POLYETHYLENEIMINE (PEI):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYETHYLENEIMINE (PEI):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of POLYETHYLENEIMINE (PEI):
-Precautions for safe handling:
*Advice on safe handling:
Handle under argon.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection. Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under argon.

STABILITY and REACTIVITY of POLYETHYLENEIMINE (PEI):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available