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DESCRIPTION
Polyglyceryl-4 Hemp Seedate is a compound that blends polyglyceryl-4, a type of emulsifier derived from glycerin, with hemp seed oil or its derivatives.
This combination is commonly found in cosmetic and skincare products.
Cas Number
29894-35-7
68956-68-3
SYNONYMS
Polyglycerol esters,Polyglyceryl derivatives,Emulsifying agent (general term),Hemp oil,Cannabis sativa seed oil,Hempseed oil
Polyglceryl-4 Hemp Seedate is a unique emulsifier derived from hemp seed oil, used in cosmetics, pharmaceuticals, and the food industry for its stabilizing, emulsifying, and skin-enhancing properties.
This article provides an in-depth review of its chemical composition, mechanism of action, industrial applications, and health benefits.
It also explores its safety, toxicity profiles, and potential for future innovations.
The review aims to present a holistic understanding of Polyglceryl-4 Hemp Seedate, highlighting its multifunctionality, sustainability, and the growing consumer demand for plant-based alternatives in formulations.
Polyglceryl-4 Hemp Seedate, an ester of hemp seed oil, is becoming increasingly popular as a multifunctional ingredient across multiple industries, particularly in natural skincare and cosmetics.
Known for its emulsifying properties, it helps combine water and oil-based ingredients, enhancing product texture, stability, and skin benefits.
As consumer demand for plant-derived and sustainable ingredients grows, Polyglceryl-4 Hemp Seedate has emerged as a prominent player.
This review examines the scientific foundations behind this compound, its industrial applications, and emerging research on its health-related properties.
Chemical and Physical Properties
Chemical Structure and Composition Polyglceryl-4 Hemp Seedate is formed by esterifying hemp seed oil with polygllycerols, specifically the tetra-glycerol form (Polyglceryl-This esterification creates a compound that has both hydrophilic and lipophilic properties, making it an effective emulsifier for cosmetic formulations.
The primary components of hemp seed oil include essential fatty acids, such as omega-3 (α-linolenic acid) and omega-6 (linoleic acid), as well as minor components like tocopherols (vitamin E), which contribute to its antioxidant properties.
Molecular Weight, Polarity, Solubility Polyglceryl-4 Hemp Seedate is a medium-molecular-weight compound that has both hydrophilic (water-attracting) and lipophilic (oil-attracting) components.
This dual polarity allows it to efficiently stabilize emulsions.
It is soluble in oils but can also interact with water in formulations, which is why it's commonly used in personal care products.
Stability and Shelf-Life Polyglceryl-4 Hemp Seedate is stable in formulations, exhibiting good resistance to oxidation.
However, the stability of the emulsifier depends on the quality of the starting hemp seed oil and the specific formulation in which it is used.
Methodology for Synthesis and Extraction Polyglceryl-4 Hemp Seedate is synthesized by esterifying polygllycerol with hemp seed oil under controlled conditions.
The process involves using catalysts to break the triglycerides in hemp seed oil, allowing polyglceryl molecules to bind to fatty acids.
Sources and Production
Origin of Polyglceryl-4 Hemp Seedate Derived from cold-pressed hemp seed oil, Polyglceryl-4 Hemp Seedate harnesses the natural benefits of hemp, such as its high essential fatty acid content, and its anti-inflammatory, antioxidant, and moisturizing properties.
Hemp cultivation is known for its environmental sustainability, as hemp is a hardy plant that requires little water, pesticides, or synthetic fertilizers.
Production Processes The production of Polyglceryl-4 Hemp Seedate involves a relatively simple esterification process where hemp seed oil is combined with polygllycerols under controlled temperature and pressure conditions.
The esterification reaction requires minimal resources and can be conducted in a green chemistry framework to reduce environmental impact.
Sustainability and Environmental Impact Hemp cultivation is highly sustainable compared to other oilseed crops.
It is biodegradable, non-toxic, and often grown with minimal environmental footprint, making it an ideal raw material for eco-conscious formulations.
Comparison to Other Natural Emulsifiers Unlike synthetic emulsifiers, such as PEG (polyethylene glycol) or surfactants derived from petrochemicals, Polyglceryl-4 Hemp Seedate is derived from renewable, plant-based sources.
This gives it a strong sustainability profile, especially in comparison to emulsifiers like lecithin or carnauba wax.
Mechanism of Action
Emulsifying Properties Polyglceryl-4 Hemp Seedate functions by reducing the surface tension between water and oil phases, allowing them to blend together.
Its amphiphilic nature, having both hydrophobic and hydrophilic components, helps to stabilize emulsions over time.
Interaction with Water and Oil Phases The compound can efficiently incorporate into both oil and water phases, stabilizing emulsions by forming micelles, which are aggregates that trap and disperse oil droplets in aqueous environments.
Effects on Product Texture and Stability In cosmetic formulations, Polyglceryl-4 Hemp Seedate can significantly enhance texture, giving products a smooth, non-greasy finish. It also increases the stability of emulsions, helping to prevent phase separation and extending shelf life.
Applications in Industry
Cosmetics and Skincare
Moisturization and Emulsification: Polyglceryl-4 Hemp Seedate is primarily used in skincare products like lotions, creams, and serums due to its ability to hydrate and enhance absorption of other active ingredients.
Anti-inflammatory Benefits: Due to the anti-inflammatory properties of hemp seed oil, this emulsifier can help soothe irritated skin, reduce redness, and provide comfort in sensitive skin formulations.
Product Examples: Found in a wide variety of products including facial cleansers, sunscreens, makeup removers, hair conditioners, and body lotions.
Pharmaceuticals
Topical Formulations: Polyglceryl-4 Hemp Seedate's skin compatibility makes it ideal for use in pharmaceutical creams, ointments, and transdermal delivery systems.
Controlled Drug Release: It can be used in controlled-release formulations for topical delivery of active pharmaceutical ingredients (APIs), improving the therapeutic efficacy of certain treatments.
Food Industry
Emulsification in Food Products: As an emulsifier, it stabilizes water and oil mixtures in various food products, including dressings, sauces, and dairy alternatives.
Health Considerations: Polyglceryl-4 Hemp Seedate is considered safe for food applications, with hemp seed oil known for its health benefits such as omega-3 fatty acids and antioxidants.
Other Uses
Biodegradable Cleaning Products: The plant-based and biodegradable nature of Polyglceryl-4 Hemp Seedate makes it a good candidate for use in green cleaning formulations.
Health Benefits
Nutritional Content of Hemp Seed Oil Hemp seed oil, the source of Polyglceryl-4 Hemp Seedate, is a rich source of essential fatty acids, including omega-3 and omega-6, which are crucial for maintaining cellular health, reducing inflammation, and supporting skin integrity.
Anti-inflammatory and Antioxidant Effects Research suggests that hemp seed oil has anti-inflammatory properties that can help with conditions like eczema, psoriasis, and acne. Polyglceryl-4 Hemp Seedate, being derived from hemp seed oil, may retain these therapeutic properties in skincare formulations.
Skin Barrier Enhancement Polyglceryl-4 Hemp Seedate can strengthen the skin’s barrier function, improving moisture retention and protecting against environmental damage.
Research Studies and Findings
Scientific Literature on Polyglceryl-4 Hemp Seedate A review of recent studies shows promising evidence of Polyglceryl-4 Hemp Seedate's effectiveness in improving skin hydration, reducing inflammation, and stabilizing emulsions in formulations.
However, more clinical studies are needed to fully understand its potential therapeutic applications.
Key Findings Studies indicate that Polyglceryl-4 Hemp Seedate can enhance the delivery of other active ingredients in topical formulations, such as vitamins and peptides, thereby increasing their bioavailability.
Comparisons with Other Emulsifiers
Traditional vs. Plant-based Emulsifiers When compared to synthetic emulsifiers like PEG-100 Stearate, Polyglceryl-4 Hemp Seedate has the advantage of being derived from renewable, plant-based sources.
It also offers skin benefits that synthetic emulsifiers often cannot match.
Market Trends There is an increasing trend toward plant-based emulsifiers in cosmetics, driven by consumer demand for eco-friendly and cruelty-free products.
Polyglceryl-4 Hemp Seedate fits this trend perfectly.
Future Directions and Innovations
Emerging Applications Future research might expand the use of Polyglceryl-4 Hemp Seedate in drug delivery systems, environmental cleaning products, and even as a base for novel food formulations.
Technological Advancements Advances in green chemistry and sustainable manufacturing processes could make Polyglceryl-4 Hemp Seedate even more cost-effective and environmentally friendly.
Conclusion
Polyglceryl-4 Hemp Seedate is a versatile, plant-based emulsifier with a broad range of applications in the cosmetics, pharmaceutical, and food industries.
Its ability to stabilize emulsions, coupled with the inherent benefits of hemp seed oil, makes it an attractive alternative to traditional emulsifiers.
As research continues and consumer demand for sustainable, natural ingredients rises, Polyglceryl-4 Hemp Seedate’s role in various industries is poised to grow.
SAFETY INFORMATION ABOUT POLYGLYCERYL-4 HEMP SEEDATE
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
