POLYGLYCOL 600

Polyglycol 600 is a clear viscous liquid polyethylene glycol. 
Polyglycol 600 is soluble in water and polar organic solvents. 
Polyglycol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols. 

CAS Number: 25322-68-3
Molecular Formula: (C2H4O)nH2O
EINECS Number: 500-038-2

Synonyms: Reaction mass of 156065-02-0 and 25322-68-3 and 68937-54-2, 937-250-3, 1,2-ethanediol, homopolymer, 2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1, Alcox E 160, Alcox E 30;alcoxe30, Poly(ethylene oxide), approx. M.W. 600,000, Poly(ethylene oxide), approx. M.W. 200,000, Poly(ethylene oxide), approx. M.W. 900,000

Polyglycol 600 is recommended for hand dishwashing detergents, wool and fine-fabric washing powders for manual washing, hand and all-purpose wash pastes, hard surface cleaners, all liquid wash and cleaning agents, especially suited for highly concentrated products, viscosity regulators, detergent boosters, solubilizers.
Polyglycol 600 is a water-soluble, non-ionic surfactant used in various industrial and pharmaceutical applications.

Polyglycol 600 acts as a moisturizer in antiperspirants, shampoos and liquid soaps, hair styling products and bar soap.
Polyglycol 600 is used as a carrier for sodium stearate & sodium aluminum hydroxylapatite in deodorants and perfumes.
A liquid polyalkylene glycol used as an antifoam agent in a wide variety of industries, including latex formulations, paper and pulp processing, emulsion paints, and food production.

Polyglycol 600 is a polyethylene glycol (PEG) polymer with an average molecular weight of 200 g/mol. 
Polyglycol 600 functions as an outstanding solubilizer for hexachlorophene and dimethyl phthalate azulene.
Polyglycol 600 has very low water content, good biodegradability and is compatible with hard water.

Polyglycol 600 is used in toothpaste where it improves consistency and storage stability.
Polyglycol 600 can also be used in bath oils and foam baths to assist the solubilizing action of the active substances for perfum.
Polyglycol 600 has a shelf life of 2 years.

Polyglycol 600 is a liquid PEG excipient grade product, produced under IPEC GMP conditions.
Polyglycol 600 is specied according to the requirements of the main international ICH guidelines and monographs.
Polyglycol 600 is clear viscous liquid at room temperature.

Polyglycol 600 can be supplied in tank trucks or in steel drums.
Polyglycol 600's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Pol.
Therefore Polyglycol 600 is soluble in water and polar organic solvents like aceton or methanol.

Polyglycol 600 is insoluble in pure hydrocarbons.
Polyglycol 600 displays typical chemical reactions of alc ohols/diols.
The solidication point, of Polyglycol 600 is about 50°C.

Besides standard grade Polyglycol 600 special quality Polyglycol 600 USP with very low concentration of monoethylenglycol a diethyleneglycol for pharamaceutical applications is available.
Polyglycol 600s are made of condensed ethylene oxide and water. 
They are widely used in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners. 

Polyglycol 600 is often used as a defoaming agent, lubricant and viscosity modifier. 
It is also used as a coating for fresh fruit, as a solvent in metal working fluids, as a binder and modifier in latex paints, and as a humectant in inks and abrasives.
Polyglycol 600, Solid detergent concentrates are used in crayons and watercolors.

Polyglycol 600 is used as a humectant, wetting and dispersing agent.
Polyglycol 600 is a petroleum-based product
Polyglycol 600 is used in the manufacture of creams and ointments.

Polyglycol 600 is an ingredient used in cosmetics and hair care products.
Polyglycol 600 is used in a number of toothpastes as a dispersant.
Polyglycol 600 is a polyethylene glycol (PEG) polymer with an average molecular weight of 600 g/mol. 

Polyglycol 600 belongs to the polyethylene glycol family, which consists of water-soluble, non-ionic polymers with various industrial, pharmaceutical, and cosmetic applications. 
Due to its higher molecular weight compared to Polyglycol 600 and Polyglycol 300, it has a more viscous, waxy, or semi-solid consistency, while still retaining excellent solubility in water and many organic solvents.
Polyglycol 600s are a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene. 

The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups. 
The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups. 
Polyglycol 600 is a clear viscous liquid polyethylene glycol.

Polyglycol 600 is soluble in water and polar organic solvents.
Polyglycol 600 is also under investigation for use in body armor, and in tattoos to monitor diabetes.
Polyglycol 600 is also used as an anti-foaming agent in food and drinks.

Polyglycol 600 is also used as a polymer host for solid polymer electrolytes.
Polyglycol 600 is used as a binder in the preparation of technical ceramics.
Polyglycol 600 is used to extend the size and durability of very large soap bubbles.

Polyglycol 600 is the main ingredient in many personal lubricants.
Polyglycol 600 is the main ingredient in the paint in paintballs.
Polyglycol 600 has a wide range of potential uses.

Polyglycol 600 is also used as a coating for fresh fruit, as a solvent in metal working uids, as a binder and modier in latex paints, and as a humectant in inks and abrasives.
Polyglycol 600 is a clear, colorless liquid at room temperature, sold in both drums and isotanks.
Polyglycol 600 can be used as a structure-directing agent to synthesize iron vanadate (FeVO4) nanoparticles via coprecipitation method.

Polyglycol 600 is obtained as a result of the polymerization of ethylene oxide with water, mono ethylene glycol or diethylene glycol.
Polyglycol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.
Polyglycol 600 is recommended for hand dishwashing detergents, wool and ne-fabric washing powders for manual washing, hand and all-purpose wash pastes, hard surface cleaners, all liquid wash and cleaning agents, especially suited for highly concentrated products, viscosity regulators, detergent boosters, solubilizers.

Polyglycol 600 is a polyalkylenglycol available as clear liquid.
Polyglycol 600 acts as a solvent and humectant

Melting point: 64-66 °C  
Boiling point: >250°C  
Tg: -67  
Density: 1.27 g/mL at 25 °C  
Bulk density: 400-500kg/m³  
Vapor density: >1 (vs air)  
Vapor pressure: <0.01 mm Hg (20 °C)  
Refractive index: n20/D 1.469  
Flash point: 270 °C  
Storage temp.: 2-8°C  
Solubility: H2O: 50 mg/mL, clear, colorless  
Form: waxy solid  
Color: White to very pale yellow  
Specific Gravity: 1.128  
pH: 5.5-7.0 (25℃, 50mg/mL in H2O)  
Viscosity: 1,650-3,850cp (1% solution @ 25°C)  
Viscosity: 11cs (99°C)  
Viscosity: 4.5cs (99°C)  
Viscosity: 5,500-8,000cp (1% solution @ 25°C)  
Viscosity: 6cs (99°C)  
Viscosity: 7.4cs (99°C)  
Viscosity: 750cp (5% solution @ 25°C)  
Viscosity: 75cp (5% solution @ 25°C)  
Viscosity: 8,000cs (99°C)  
Viscosity: 8,800-17,600cp (5% solution @ 25°C)  
Viscosity: 93cs (99°C)  
Biological source: synthetic (organic)  
Water solubility: Soluble in water.  
λmax: λ: 260 nm Amax: 0.6  
λ: 280 nm Amax: 0.3  
Sensitive: Hygroscopic  
Merck: 14,7568  
α-end: hydroxyl  
Ω-end: hydroxyl  
Stability: Stable. Incompatible with strong oxidizing agents.  
LogP: -0.698 at 25℃  
Surface tension: 43.5mN/m at 20°C  

Polyglycol 600 is a polyalkylene glycol (PAG) and used as a lubricant and mold release agent for rubber and elastomer processing.
Polyglycol 600 oers low friction coecients, excellent wear properties and good thermal-oxidative stability/conductivity.
Polyglycol 600 shows excellent compatibility with other formulation components.

Polyglycol 600 has a low foaming tendency, broad registration status, free of hazard label for easy and safe handling.
Polyglycol 600 can be operable in a wide temperature range with a high viscosity index.
Polyglycol 600 is a polyalkylenglycol that is used for a wide variety of applications including: reactive diol/polyether component in polyester or polyurethene resins; component of auxiliaries for leather and textile processing; cosmetic formulations; lubricant and mould release agent for rubber and elastomer processing; plasticizer and binder for ceramic and concrete manufacturing; component of lubricant formulations; water soluble, lubricating component in metalworking uids; humectant for paper, wood and cellulose lms; solvent and humectant for dyes and inks; modier for production of regenerated viscose; humectant and plasticizer for adhesives; and heat transfer medium.

Polyglykol PR 600 is a clear neutral liquid at room temperature, and the molecular weight is 570 – 630g/mol.
Its two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol PR 600.
The solidication point of Polyglykol PR 600 is about 20 °C lower than that of the polyethylene glycol 600.
This simplies handling of Polyglykol PR 600 at low temperature

Polyglycol 600 as being an addition polymer of ethylene oxide and water. 
Polyglycol 600 are liquids; grades 1000 and above are solids at ambient temperatures.
Liquid grades (PEG 200–600) occur as clear, colorless or slightly yellow-colored, viscous liquids. 

They have a slight but characteristic odor and a bitter, slightly burning taste.
Polyglycol 600 can occur as a solid at ambient temperatures.
Solid grades (PEG>1000) are white or off-white in color, and range in consistency from pastes to waxy flakes. 

Grades of Polyglycol 600 and above are available as freeflowing milled powders.
Any of several condensa-tion polymers of ethylene glycol with thegeneral formula HOCH2(CH2OCH2)nCH2OH orH(OCH2CH2)nOH. 
Average molecular weightsrange from 200 to 6000 properties vary with molec-ular weight.

A structure-directing agent to synthesize iron vanadate (FeVO4) nanoparticles via co-precipitation method.
An organic additive to prepare crystalline nanorods of calcium tungstate (CaWO4) using calcium chloride and sodium tungstate via solvothermal process.
A surface modifier in the synthesis of calcium peroxide nanoparticles using CaCl2 as a precursor via hydrolysis-precipitation method.

A green solvent in combination with H2O in the preparation of 4-sulfanylcoumarins by sulfanylation of 4-tosyloxycoumarins with thiourea and alkyl halides.
The ring-opening polymerization of ethylene oxide is readily effected by a variety of ionic reagents and several types of polymer have been prepared. 
For commercial purposes, poly(ethylene oxide)s of low molecular weight and of very high molecular weight are of interest.

Polyglycol 600 is insoluble in pure hydrocarbons.
Polyglycol 600 is compatible with cellulose, polyester and polyurethane.
Polyglycol 600 is suitable for use in cellulose lms, dyes and inks.

Polyglycol 600 acts as a lubricant and solvent. 
It is biodegradable, molecularly stable, low-toxic, low-odor and non-volatile. 
Polyglycol 600 is free of BSE, GMO and preservatives. 

Polyglycol 600 exhibits excellent hygroscopicity and acts as a base/carrier in silver polish. 
Polyglycol 600 is used in inks. 

Uses Of Polyglycol 600:
Polyglycol 600 is widely used as a lubricant and coolant in industrial applications, including metalworking fluids, hydraulic fluids, and gear oils. 
Its low volatility, excellent lubricity, and ability to reduce friction make it an ideal choice for high-performance lubrication in heavy machinery, engines, and heat-exchange systems. 
Polyglycol 600 is particularly valuable in applications where water-soluble lubricants are required.

Polyglycol 600 is an important component in paint, coating, and ink formulations, where it functions as a dispersant, humectant, and viscosity stabilizer.
Polyglycol 600 is a highly versatile, water-soluble polymer that is widely utilized across multiple industries due to its lubricating, humectant, emulsifying, and stabilizing properties. 
Its relatively high molecular weight and viscous or semi-solid consistency allow it to perform effectively in pharmaceutical, cosmetic, industrial, and food applications, where it enhances moisture retention, improves solubility, and provides lubrication for various formulations.

Below is a detailed explanation of its key applications:
Polyglycol 600 is used as an intermediate in chemical synthesis.
Polyglycol 600 is used in Electroplating processes.

Polyglycol 600 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. 
The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH.
Polyglycol 600 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.

Polyglycol 600 used in medicines for treating disimpaction and maintenance therapy for children with constipation
Polyglycol 600 is commonly used as a base fluid or additive in industrial lubricants, metalworking fluids, and hydraulic oils, where its low volatility, excellent lubricity, and resistance to oxidation make it ideal for use in high-performance machinery. 
Polyglycol 600 helps to reduce friction, prevent wear and tear on metal surfaces, and improve overall operational efficiency, particularly in equipment that operates under high temperatures or extreme pressures. 

Additionally, Polyglycol 600 is frequently used in heat transfer fluids, where its thermal stability and high boiling point ensure efficient heat dissipation, thereby preventing overheating in industrial systems.
Polyglycol 600 is a highly functional, water-soluble polymer with applications across a diverse range of industries, including industrial lubrication, pharmaceuticals, cosmetics, food processing, plastics, agriculture, and coatings. 
Its unique ability to retain moisture, improve solubility, enhance lubrication, and stabilize formulations makes it an essential ingredient in countless consumer and industrial products. 

Additionally, Polyglycol 600s biodegradable and non-toxic nature further increases its appeal in sustainable and environmentally friendly applications.
Polyglycol 600 is industrially produced as a lubricating substance for various surfaces to reduce friction. 
Polyglycol 600 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.

Polyglycol 600 is a binder, coating agent, dispersing agent, flavoring adjuvant, and plasticizing agent that is a clear, colorless, viscous, hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration. 
Polyglycol 600 is soluble in water (mw 1,000) and many organic solvents.
Polyglycol 600 is a binder, solvent, plasticizing agent, and softener widely used for cosmetic cream bases and pharmaceutical ointments.

Polyglycol 600s are quite humectant up to a molecular weight of 500 beyond this weight, their water uptake diminishes.
Polyglycol 600 is used as a dough thickener in the textile industry.
They can be used as solvent and dispersant media in the paint and ceramic industry.

Polyglycol 600 is used as a solvent and dispersant.
Polyglycol 600 is used as a viscosity adjuster.
Polyglycol 600 is used in the Rubber industry.

Polyglycol 600 is used as a plasticizer, dehumidier and impregnation agent.
Polyglycol 600 is used as a lubricant and a mold release agent.
Polyglycol 600 is used as an intermediate in chemical synthesis.

Polyglycol 600 is used in Electroplating processes.
Used in conjunction with carbon black to form a conductive composite.
Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.

Polyglycol 600 is also known as polyoxirane (PEO). 
Polyglycol 600 is a linear polyether obtained by ring opening polymerization of ethylene oxide. 
The main uses in the field of biomedicine are as follows: Contact lens liquid. 

The viscosity of Polyglycol 600 solution is sensitive to the shear rate and it is not easy for bacteria to grow on polyethylene glycol.
Polyglycol 600 plays a significant role in pharmaceutical formulations due to its non-toxic, biocompatible, and water-soluble nature. 
It is commonly used as an excipient, carrier, humectant, and stabilizing agent in various drug delivery systems, including:

Topical creams, ointments, and gels, where it helps to retain moisture, improve texture, and enhance the absorption of active ingredients into the skin.
Oral medications and liquid suspensions, where it functions as a binder, solubilizer, and viscosity modifier, ensuring even dispersion of active pharmaceutical ingredients (APIs) for better bioavailability.
Capsule and tablet coatings, providing a protective, moisture-resistant film that improves the stability, dissolution rate, and shelf life of medications.
Injectable formulations, where it serves as a carrier or solubilizing agent to enhance the delivery of drugs that have limited water solubility.

In the cosmetics and personal care industry, Polyglycol 600 is highly valued for its moisturizing, emulsifying, and texturizing properties, making it a common ingredient in products designed for skin, hair, and oral care. 
Moisturizing lotions and creams, where it acts as a humectant, helping the skin retain moisture and preventing dryness.
Shampoos, conditioners, and hair treatments, where it improves foam stability, enhances texture, and provides a smooth, silky feel to the hair.

Toothpastes and mouthwashes, where it functions as a humectant and viscosity modifier, preventing the product from drying out while ensuring an even and consistent texture.
Soaps, body washes, and cleansers, where it enhances foam production, reduces irritation, and provides a gentle cleansing effect.

Safety Profile Of Polyglycol 600:
Polyglycol 600 is generally considered safe, non-toxic, and biodegradable under normal usage conditions. 
However, like any chemical substance, improper handling, excessive exposure, or specific industrial applications can pose certain health, environmental, and fire-related hazards. 
While Polyglycol 600 is generally non-irritating and even used in skincare products, prolonged or repeated exposure to large amounts may cause mild skin dryness, irritation, or dermatitis in sensitive individuals.

Wear protective gloves if handling it frequently in industrial or laboratory settings, especially in concentrated or heated forms.
Potential Irritation: Direct contact with the eyes may cause temporary irritation, redness, or discomfort, but it is not classified as a severe eye irritant.
If contact occurs, rinse eyes immediately with plenty of clean water for at least 15 minutes.

Due to its low volatility, Polyglycol 600 does not easily form vapors under normal conditions. 
However, inhalation of mists, aerosols, or heated vapors may cause mild respiratory irritation in sensitive individuals.
In industrial settings, ensure proper ventilation and use protective masks if working with Polyglycol 600 in spray form or at high temperatures.

Polyglycol 600 has a low level of acute toxicity and is even used in food and pharmaceutical applications. 
However, excessive ingestion may lead to gastrointestinal discomfort, nausea, or diarrhea.
If swallowed in large amounts, rinse the mouth with water and drink plenty of fluids. 

Absorbed Polyglycol 600 is excreted largely unchanged in the urine, although polyethylene glycols of low molecular weight may be partially metabolized.
The WHO has set an estimated acceptable daily intake of polyethylene glycols at up to 10 mg/kg body-weight.
In parenteral products, the maximum recommended concentration of Polyglycol 600 is approximately 30% v/v as hemolytic effects have been observed at concentrations greater than about 40% v/v.