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POLYGLYKOL 600

Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer. 
Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols. 
Polyglykol 600 is recommended for highly concentrated products, viscosity regulators, detergent boosters, solubilizers and oral care applications.

CAS Number: 25322-68-3
Linear Formula: H(OCH2CH2)nOH

Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer. 
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols. 
Polyglykol 600 is recommended for hand dishwashing detergents, wool and fine-fabric washing powders for manual washing, hand and all-purpose wash pastes, hard surface cleaners, all liquid wash and cleaning agents, especially suited for highly concentrated products, viscosity regulators, detergent boosters, solubilizers.

Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer. 
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 is a clear viscous liquid polyethylene glycol. 
Polyglykol 600 is soluble in water and polar organic solvents. 

Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols. 
Polyglykol 600 is recommended for highly concentrated products, viscosity regulators, detergent boosters, solubilizers and oral care applications.

Polyglykol 600 is a liquid Polyglykol excipient grade product, produced under IPEC GMP conditions.
Polyglykol 600 is specified according to the requirements of the main international ICH guidelines and monographs.

Polyglykol 600 is a clear viscous liquid polyethylene glycol. 
Polyglykol 600 is soluble in water and polar organic solvents. 

Polyglykol 600 is a non-volatile humectant based on polyethylene glycol. 
Polyglykol 600 acts as a moisturizer in antiperspirants, shampoos and liquid soaps, hair styling products and bar soaps.

Polyglykol 600 has very low water content, compatiblility with hard water, good biodegradability and outstanding toxicological safety.
Polyglykol 600 is also used in toothpastes where Polyglykol 600 improves consistency and storage stability.

Polyglykol 600 can also be used in bath oils and foam baths to assist the solubilizing action of the active substances for perfume oils.
Polyglykol 600 is also an ideal carrier for sodium stearate and sodium aluminium hydroxylactate in deodorants, perfumes and insect-repellent sticks.
Polyglykol 600 is stable for 2 years when stored in the original sealed containers in a cool, dry place.

Polyglykol 600 is a clear viscous liquid polyethylene glycol. 
Polyglykol 600 is soluble in water and polar organic solvents. 

Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols. 
Polyglykol 600 is recommended for highly concentrated products, viscosity regulators, detergent boosters, solubilizers and oral care applications.

Polyglykol 600 is a clear viscous liquid polyethylene glycol. 
Polyglykol 600 is soluble in water and polar organic solvents. 

Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols. 
Polyglykol 600 is recommended for hand dishwashing detergents, wool and fine-fabric washing powders for manual washing, hand and all-purpose wash pastes, hard surface cleaners, all liquid wash and cleaning agents, especially suited for highly concentrated products, viscosity regulators, detergent boosters, solubilizers.

Uses of Polyglykol 600:
Polyglykol 600 is used in paints and coatings.
Polyglykol 600 is also used in toothpastes where Polyglykol 600 improves consistency and storage stability.
Polyglykol 600 can also be used in bath oils and foam baths to assist the solubilizing action of the active substances for perfume oils.

Other Uses:
Toiletries (Shower and Bath, Oral care) - Antiperspirants and deodorants
Toiletries (Shower and Bath, Oral care) - Oral care
Toiletries (Shower and Bath, Oral care) - Shower and bath - Toilet Soaps
Creams, lotions and gels
Hair care (Shampoos, Conditioners and Styling) - Shampoos
Perfumes and fragrances - Perfumes

Applications of Polyglykol 600:
Polyglykol 600 can be used in liquid pharmaceutical preparations such as drops or fillings for gelatin capsules. 

Polyglykol 600 is also used in toothpastes where Polyglykol 600 improves consistency and storage stability. 
Polyglykol 600 acts as a moisturizer in antiperspirants, shampoos and liquid soaps, hair styling products and bar soap.

Polyglykol 600 can also be used in bath oils and foam baths to assist the solubilizing action of the active substances for perfume oils.
Polyglykol 600 is also an ideal carrier for sodium stearate and sodium aluminium hydroxylactate in deodorants, perfumes and insect-repellent sticks.

Industrial Applications:

Polyglykol 600 is due to their physical and chemical properties polyethylene glycols are used for a wide variety of applications as:

Reactant:
Polyglykol 600 is reactive diol/polyether component in polyester or polyurethane resins.

Solvent / Humectant / Plasticizer:
Polyglykol 600 is used in paper, wood, cellulose films, inks, paints, coatings, adhesives, sealants, concrete.

Release agent / Lubricant:
Polyglykol 600 is mould release agent for rubber and elastomer processing, lubricant formulations, metal working fluids.

Polyglykol 600 is binder for ceramics.
Polyglykol 600 is component of auxiliaries for fiber, textile and leather processing.

Other Applications:
Shower, Liquid Soap
Shampoo
Syndet, Bar Soap
Hair Styling
Cream, Lotion
Antiperspirant and Deodorant

Benefits of Polyglykol 600:
Good solubility in water
Very low water content
Compatible with hard water
Non-volatile
Outstanding toxicological safety
Good biodegradability

Properties of Polyglykol 600:
The physical and chemical properties of polyethylene glycols are mainly determined by the two hydroxyl end groups, the ether groups as well as the molecular weight. 
Polyglykol 600 is a clear viscous liquid at 30 °C.

Polyglykol 600 is soluble in water and polar organic solvents like acetone or methanol. 
Polyglykol 600 is insoluble in pure hydrocarbons.

Polyglykol 600 shows typical chemical reactions of alcohols/diols and a very low evaporation rate. 
The solidification point of Polyglykol 600 is about 20 °C. 

Beside our standard quality Polyglykol 600 PU with reduced amounts of residual alkali and water is available.  
We recommend Polyglykol 600 PU especially for polyurethane synthesis.

Shipping and Storage of Polyglykol 600:
Polyglykol 600 can be supplied in tank trucks, IBCs or in steel drums.
When stored in a cold, dry place in a closed container Polyglykol 600 can be kept for at least two years.

Storage of Polyglykol 600:
Polyglykol 600 is stable for 2 years when stored in the original sealed containers in a cool, dry place.

Furthermore the containers should not be exposed to direct sun light. 
Ambient temperatures for long term storage are preferably between 10°C and 25°C and between 0°C and 30°C as maximum. 

Storage at higher temperatures is possible only for a short time and should be kept below the solidification point of Polyglykol 600.
The most suitable material for storage tanks is stainless steel, pure aluminium, rubber-or polyethylenelined containers and storage tanks made from glass-fibre-reinforced polyester (GRP). 

The tank should be ventilated by means of a silica gel dryer. 
Conventional steel tanks are of limited suitability because after prolonged storage Polyglykol 600 may become discoloured owing to traces of iron.

Polyglykol 600 solidifies when stored in a cool place and must be melted before use. 
This is best carried out in heating chambers, but the outside temperature should not exceed about 60°C. 

This must also be ensured when electrical drum heaters are used. 
Electrical immersion heaters are not suitable for melting due to the high thermal stress occurring.

Safety of Polyglykol 600:
Polyglykols are non-toxic and physiologically safe so no special safety precautions need to be taken when handling them. 
For many applications, particularly in pharmaceuticals, cosmetics and foodstuffs packging, the physiological safety of Polyglykol is important. 

When administered orally and cutaneously they are to be rated as non-toxic. 
The vapour pressure of Polyglykol is so low that inhalation of relevant amounts is impossible. 
Because of their good physiological tolerability Polyglykol were first included in the US pharmacopoeia already in 1950. 

Since then they have been listed in numerous pharmacopoeias. 
The tolerability of Polyglykol in animals improves as the degree of polymerization rises. 

Polyglykol have no toxic or irritant effect on the skin. 
Because of low toxicity Polyglykol 600 was not possible to establish an exact LD50 resulting from skin penetration.

Ecological Data:
The behaviour of Polyglykol in effluent is a matter of crucial importance, e.g. in their industrial use in the textile sector and in metal processing. 
The rate of biodegradation of Polyglykol decreases with increasing molar mass. 

Polyglykol up to molar mass 1500 are regarded as readily biodegrad able (Zahn-Wellens test). 
The microbiological degradation of other substances is not inhibited by the presence of Polyglykol. 

The toxic inhibition limit for bacteria in the fermentation tube test is 5000 mg/l. 
Investigations within our own labs have shown that even in concentrations of 10000 mg/kg (1%) polyethylene glycols have no adverse effect on fish (crucian carp). 

Polyglykolss in concentration up to 10000 mg/l exhibit no harmful effect of any kind towards daphnia and protozoa. 
The German water hazard class is WGK 1.

Waste Disposal:
Any Polyglykol to be disposed of waste can be taken, in accordance with the local regulations, to a special waste incineration plant. 
None of Polyglykol, in concentrations up to 10,000 mg/l water, demonstrates an acute harmful effect on fish or bacteria. 

Polyglykol with molar masses of 200 to 1500 have good biodegradability. 
Polyglykol 600 is therefore possible to take them to a biological sewage treatment plant after consulting the operator provided the water and waste regulations permit.

Stability and Reactivity of Polyglykol 600:

Reactivity: 
No dangerous reaction known under conditions of normal use.

Chemical stability: 
Stable under normal conditions.

Possibility of hazardous reactions: 
No dangerous reaction known under conditions of normal use.

Conditions to avoid: 
None known.

Incompatible materials: 
not known

Hazardous decomposition: 
When handled and stored appropriately, no dangerous

Handling and Storage

Advice on protection against fire and explosion: 
Observe the general rules of industrial fire protection.

Advice on safe handling: 
Avoid contact with skin and eyes.

Conditions for safe storage: 
Keep only in the original container.

Further information on storage conditions: 
Store in a cool, dry, well-ventilated area. 
Keep container sealed when not in use.

Keep in an area equipped with sprinklers.
Keep from freezing.

First Aid Measures of Polyglykol 600:

General advice: 
Remove contaminated clothing and shoes.

If inhaled: 
Move the victim to fresh air.
Give oxygen or artificial respiration if needed.

Get immediate medical advice/ attention.
Never give anything by mouth to an unconscious person.

In case of skin contact: 
Wash thoroughly with soap and water for 15 minutes. If skin
irritation occurs, seek medical attention.

In case of eye contact: 
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Get medical attention immediately if irritation develops and persists.

If swallowed: 
Immediately call a POISON CENTER/doctor.

Most important symptoms and effects, both acute and delayed: 
The possible symptoms known are those derived from the labelling.
No additional symptoms are known.

Notes to physician: 
Treat symptomatically.

Firefighting Measures of Polyglykol 600:

Suitable extinguishing media: 
Dry powder
Foam
Carbon dioxide (CO2)
Water spray jet

Unsuitable extinguishing media: 
High volume water jet

Specific hazards during firefighting: 

In case of fires, hazardous combustion gases are formed:
Carbon monoxide (CO)
Carbon dioxide (CO2)
Burning produces noxious and toxic fumes.

Further information: 
Exercise caution when fighting any chemical fire. 
Use NIOSH approved self-contained breathing apparatus and full protective clothing.

Special protective equipment for firefighters: 
Wear an approved positive pressure self-contained breathing apparatus in addition to standard fire fighting gear.

Accidental Release Measures of Polyglykol 600:

Personal precautions, protective equipment and emergency procedures: 
Wear suitable protective equipment.
Ensure adequate ventilation.
Wearing appropriate personal protective equipment, contain spill, collect onto inert absorbent, and place in a suitable container.

Environmental precautions: 
Do not allow contact with soil, surface or ground water.
Prevent Polyglykol 600 from entering drains.

Methods and materials for containment and cleaning up: 
Dilute with plenty of water.

Identifiers of Polyglykol 600:
Composition:
Polyethylene glycol
H(OCH2CH2)nOH
n = 13
CAS-No.: 25322-68-3
INCI-description: PEG-12

Trade name: POLYGLYKOL 600
Material number: 107921
CAS number: 25322-68-3
Synonyms: Product Has No Synonyms
Primary product use: Techno-chemical industry.
Chemical family: polyethylene glycol, HO-(CH2-CH2-O)n-H, average molecular mass 600

Synonym(s): PEG
Linear Formula: H(OCH2CH2)nOH
CAS Number: 25322-68-3
MDL number: MFCD00081839
PubChem Substance ID: 24887677

Chemical Composition: Polyethylene glycol
CAS Number: 25322-68-3
Physical Form: Wax
Appearance: Colorless
Product Status: COMMERCIAL

INCI Names: PEG-12
Chemical Composition: Polyethylene glycol
CAS Number: 25322-68-3
Appearance: Liquid, clear, viscous
Odor: Characteristic
Color: Colorless
Product Status: COMMERCIAL

Physical and Chemical Properties of Polyglykol 600:
Appearance: Liquid
Colour: colourless
Odour: characteristic
pH: 5 - 7 (68 °F / 20 °C)
Concentration: 100 g/l
Freezing point: 63 - 72 °F / 17 - 22 °C
Boiling point: no data available
Flash point: 500 °F / 260 °C
Flammability (solid, gas): Not applicable
Vapour pressure: < 0.1 mbar (68 °F / 20 °C)
Relative vapour density: no data available
Density: approx. 1.12 g/cm3 (68 °F / 20 °C)
Solubility(ies):
Water solubility: miscible (68 °F / 20 °C)
Partition coefficient: noctanol/water: log Pow: < -1
Auto-ignition temperature: - 608 °F / - 320 °C
Decomposition temperature: 680 °F / 360 °C
Viscosity:
Viscosity, dynamic: 16 - 19 mPa.s (68 °F / 20 °C)
Viscosity, kinematic: 14 - 17 mm2/s (68 °F / 20 °C)
Metal corrosion rate: Not applicable
Particle size: Not applicable

Mol wt: 570-630
Refractive index: n20/D 1.469
Viscosity: 150-190 mPa.s(20 °C)
mp: 17-22 °C (lit.)
Density: 1.12 g/mL at 20 °C
SMILES string: C(CO)O
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

INCI-PEG: 12
Hazen Colour 25% a.i.in water: max. 15
Molecular Mass [g/mol]: 570-630
OH value [mg koh/g]: 178-197
Solidification point [°C]: 17-22
Viscosity at 20°C [mPa·s]: 50% 17-18
Viscosity at 98.8°C=270°F [mm²/s]: 9.9-11.3
PH 5% aqueous solution: 5.0-7.5
Water content [% M/M]: max. 1
Density at 20°C [g/cm³]: 1.126
Vapour pressure at 20°C [hPa]: < 0.01
Solubility in Water at 20°C [% M/M]: ∞

Other Descriptions of Polyglykol 600:

Chemical Name:
PEG-12

Product Function:
Humectant

Chemical Type:
Polyethylene Glycol

Performance Claims:
Water-soluble
Moisturizing
Antiperspirant
Conditioning

Chemical Name:
Polyethylene glycol, average molar mass 600 g/mol

Pharmacopoeia Name:
USP-NF: Polyethylene glycol 600, Ph. Eur.: Macrogol 600

Physical appearance:
Liquid

Quality status:
Excipient, IPEC GMP; Kosher certificate

Application function:
Solvent, Coating ingredient, Viscosity Enhancer

Product Type: 
Solvents - Glycols and Glycol Ethers - Ethylene Glycols
Plasticizers
Humectants

Applications/ Recommended for: Coatings

Claims: 
Antiperspirants / Deo-actives
Humectants - Polyols
Moisturizing Agents
Solvents and Carriers
moisturizing

Regulatory Status: 
US, EU

Other Polyglykol Products:
Polyglykol 1000
Polyglykol 1000 SG VITA
Polyglykol 10000 S
Polyglykol 10000 SG
Polyglykol 12000 S
Polyglykol 1500 FL PU
Polyglykol 1500 S
Polyglykol 2000 PU 
Polyglykol 2000 S
Polyglykol 300
Polyglykol 400
Polyglykol 4000 S
Polyglykol 600 PU
Polyglykol 6000 P
Polyglykol 8000 P
Polyglykol 8000 S
Polyglykol 9000 S
Polyglykol AM 1100
Polyglykol AM 250
Polyglykol AM 450
Polyglykol D 21/150
Polyglykol D 21/300
Polyglykol D 21/700
Polyglykol G 500
Polyglykol M 1000
Polyglykol M 2000 FL
Polyglykol M 2000 S
Polyglykol M 350
Polyglykol M 350 PU
Polyglykol M 500
Polyglykol M 500 PU
Polyglykol M 750
Polyglykol M 750 PU
Polyglykol 10000 FL
Polyglykol 1500 FL
Polyglykol 1500 PS
Polyglykol 200 LVC
Polyglykol 2000 FL
Polyglykol 3400 FL
Polyglykol 3400 PS
Polyglykol 4000 PS
Polyglykol 4000 FL
Polyglykol 4000 M50
Polyglykol 4000 P
Polyglykol 4000 PF
Polyglykol 4000 PSK
Polyglykol 6000 FL
Polyglykol 6000 PF
Polyglykol 6000 PS
Polyglykol 8000 FL
Polyglykol 8000 PF
Polyglykol 8000 PS
Polyglykol 9000 FL
Polyglykol A 11/1800
Polyglykol A 32/550
Polyglykol A 400
Polyglykol A 500
Polyglykol PR 600
 

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