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Polyhexanide (polyhexamethylene biguanide, PHMB) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Polyhexanide (polyhexamethylene biguanide, PHMB) is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.
Polyhexanide (polyhexamethylene biguanide, PHMB) is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
CAS Number: 32289-58-0
Molecular Formula: C10H23N5
Molecular Weight: 213.32312
EINECS Number: 1308068-626-2
Synonyms: 3030-47-5, 1,1,4,7,7-Pentamethyldiethylenetriamine, Pentamethyldiethylenetriamine, N,N,N',N'',N''-Pentamethyldiethylenetriamine, PMDT, N1-(2-(Dimethylamino)ethyl)-N1,N2,N2-trimethylethane-1,2-diamine, PMDETA, PMDTA, N,N,N',N',N''-Pentamethyldiethylenetriamine, Pentamethyldiethylenetriaminek, Bis(2-dimethylaminoethyl)(methyl)amine, 2,5,8-Trimethyl-2,5,8-triazanonane, N,N',N''-Pentamethyldiethylenetriamine, pmdien, NSC 65659, n,n,n,n,n-pentamethyldiethylenetriamine, 1,2-Ethanediamine, N-[2-(dimethylamino)ethyl]-N,N',N'-trimethyl-, Diethylenetriamine, 1,1,4,7,7-pentamethyl-, 3274UTY3HL, DTXSID7029249, CHEBI:39475, MFCD00014876, NSC-65659, 1,2-Ethanediamine, N-(2-(dimethylamino)ethyl)-N,N',N'-trimethyl-, N'-[2-(dimethylamino)ethyl]-N,N,N'-trimethylethane-1,2-diamine, N-[2-(dimethylamino)ethyl]-N,N',N'-trimethylethane-1,2-diamine, 1,2-Ethanediamine, N1-(2-(dimethylamino)ethyl)-N1,N2,N2-trimethyl-, 2,2'-(methylazanediyl)bis(N,N-dimethylethanamine), N-(2-(dimethylamino)ethyl)-N,N',N'-trimethyl-1,2-ethanediamine, N-[2-(Dimethylamino)ethyl]-N,N',N'-trimethyl-1,2-ethanediamine, EINECS 221-201-1, BRN 1741396, UNII-3274UTY3HL, 1,2-Ethanediamine, N1-[2-(dimethylamino)ethyl]-N1,N2,N2-trimethyl-, (2-{2-(dimethylamino)ethylamino}ethyl)dimethylamine, Pentamethyldethylenetramne, N,N,N',N',N"-Pentamethyldiethylenetriamine, pentamethyldiethyenetriamine, EC 221-201-1, pentamethyl diethylentriamine, pentamethyl-diethylentriamine, pentamethyl diethylenetriamine, pentamethyldiethylene-triamine, Pentamethyldiethylenetriamine;, SCHEMBL37515, pentamethyl diethylene triamine, DTXCID109249, CHEMBL3183641, UKODFQOELJFMII-UHFFFAOYSA-, N,N''-Pentamethyldiethylenetriamine, N-(2-dimethylaminoethyl)-N,N',N'-trimethylethane-1,2-diamine, NSC65659, N-(Methoxycarbonyl)-2-propenylamine, Tox21_200681, Bis-(2-dimethylaminoethyl)methylamine, AKOS015915357, 1,4,7,7-Pentamethyldiethylenetriamine, WLN: 1N1&2N1&2N1&1, 1,1,4,7,7-pentamethyldiethlenetriamine, NCGC00248795-01, NCGC00258235-01, 1,1,4,7,7-pentamethyldiethlene triamine, Diethylenetriamine,1,4,7,7-pentamethyl-, LS-13731, CAS-3030-47-5, N,N',N',N''-Pentamethyldiethylenetriamine, CS-0077160, NS00004531, P0881, N,N',N'',N''-pentamethyldiethylene triamine, N,N,N',N',N''-Pentamethyidiethylenetriamine, D78228, EN300-175590, N,N,N', N'',N''-pentamethyldiethylenetriamine, N,N,N',N'',N''-pentamethyldiethylene triamine, A934684, Q965311, J-017894, J-523896, 1, N-[2-(dimethylamino)ethyl]-N,N',N'-trimethyl-, N,N,N',N'',N''-Pentamethyldiethylenetriamine, 99%, N-(2-(Dimethylamino)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin, N'-(2-dimethylaminoethyl)-N,N,N'-trimethyl-ethane-1,2-diamine, N-(2-dimethylamino-ethyl)-N,N',N'-trimethyl-ethane-1,2-diamine, N-(2-dimethylaminoethyl)-N,N',N'-trimethyl-ethane-1,2-diamine, N1-(2-(dimethylamino)ethyl)-N1,N2,N2-trimethyl-1,2-ethanediamine, Pentamethyldiethylenetriamine N,N,N,N,N``-Pentamethyldiethylenetriamine, InChI=1/C9H23N3/c1-10(2)6-8-12(5)9-7-11(3)4/h6-9H2,1-5H3
Polyhexanide (polyhexamethylene biguanide, PHMB) belongs to the biguanide class of chemicals, which are known for their antimicrobial properties.
Polyhexanide (polyhexamethylene biguanide, PHMB) is commonly found in various consumer products such as contact lens solutions, wound care products, and swimming pool disinfectants.
Polyhexanide (polyhexamethylene biguanide, PHMB) works by disrupting the cell membranes of microorganisms, leading to their destruction.
The preparation method of Polyhexanide (polyhexamethylene biguanide, PHMB):By a certain proportion of 1; the own bisguanides of 6-and catalyst join in reaction vessel; under nitrogen protection, said mixture is heated to 80-200 DEGC and reacts, react 2-24 hour; reaction terminates; cooling blowing, obtains poly hexamethylene biguanide, poly hexamethylene biguanide aqueous acid is neutralized to pH value 5-9; and performing filtering so as to obtain a polyhexamethylene biguanidine salt.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic.
In dermatological use, it is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide.
Polyhexanide (polyhexamethylene biguanide, PHMB) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.
Products containing Polyhexanide (polyhexamethylene biguanide, PHMB) are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.
Polyhexanide (polyhexamethylene biguanide, PHMB) is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in the majority of formulations.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer composed of repeating units of hexamethylene biguanide.
Polyhexanide (polyhexamethylene biguanide, PHMB)s chemical formula is (C8H18N4)n, where n represents the number of repeating units.
Polyhexanide (polyhexamethylene biguanide, PHMB) exhibits strong antimicrobial activity against bacteria, viruses, fungi, and algae.
Polyhexanide (polyhexamethylene biguanide, PHMB) disrupts the cell membranes of microorganisms, leading to cell lysis and death.
This mechanism of action makes it effective against a wide range of pathogens.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in various medical and healthcare products such as wound care solutions, antiseptic creams, and contact lens solutions.
Polyhexanide (polyhexamethylene biguanide, PHMB) helps prevent infections and promotes wound healing.
Polyhexanide (polyhexamethylene biguanide, PHMB) is found in personal care products like soaps, shampoos, and skincare formulations for its antimicrobial properties.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in textile treatments to impart antimicrobial properties to fabrics, especially in healthcare settings where hygiene is crucial.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used as a disinfectant in swimming pools, spas, and water purification systems to control microbial growth and ensure water safety.
Polyhexanide (polyhexamethylene biguanide, PHMB) is utilized in various industrial processes where microbial contamination needs to be controlled, such as in the manufacturing of paints, coatings, and adhesives.
Polyhexanide (polyhexamethylene biguanide, PHMB) is generally considered safe for its intended applications when used according to recommended guidelines.
However, like any chemical, it should be handled with care to avoid adverse effects.
Proper concentration and usage are important to prevent irritation or sensitization in some individuals.
Regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Chemicals Agency (ECHA) have established guidelines and regulations for the use of Polyhexanide (polyhexamethylene biguanide, PHMB) in consumer products to ensure its safety and efficacy.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a new environment-friendly cationic water-soluble polymer.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.
Polyhexanide (polyhexamethylene biguanide, PHMB) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a high molecular polymer, which is easy to be washed away.
Polyhexanide (polyhexamethylene biguanide, PHMB) is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexanide (polyhexamethylene biguanide, PHMB) is non-toxic to human cells.
Skin irritancy test of rabbits and human hands shows that Polyhexanide (polyhexamethylene biguanide, PHMB) is non-irritant to animal and human skin.
Polyhexanide (polyhexamethylene biguanide, PHMB) is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexanide (polyhexamethylene biguanide, PHMB) can be used as a disinfectant for almost all kinds of bacteria.
Polyhexanide (polyhexamethylene biguanide, PHMB) or Polyhexamethylene biguanide hydrochloride, is a cationic biguanide polymer bioci antimicrobial applications.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a substance that controls, prevents, or destroys harmful microorganisms (i.e., bacter fungi) on inanimate objects and surfaces.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a disinfectant with a broad spectrum of activity against bacteria, viruses, and fungi.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a cationic biocide marketed worldwide due to its excellent antimicrobial activity, chem toxicity, and reasonable cost.
Polyhexanide (polyhexamethylene biguanide, PHMB) destroys or irreversibly inactivates most pathogenic microorganisms.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a broad-spectrum antiseptic that avoids many efficacy and toxicity problems associat antimicrobials; in particular, it has a low risk of loss of susceptibility due to acquired antimicrobial resistance.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used as a sanitizer, bactericide ( antibacterial ), antiseptic, and disinfectant, widely eff positive and negative gram bacteria with applications in surface cleaners, hand cleaners/sanitizing, close to neutral powder de polymers, antimicrobial and dishwashing liquids, and other personal care applications with microbial activity.
20% Aqueous solution of Polyhexanide (polyhexamethylene biguanide, PHMB) is used as a biocide, antibacterial, Disinfectant, and Virucidal.
At a 1% to 2% dosage, this can be an adequate replacement for alcohol in your products as a water-based disinfectant.
This is very effective compared to Benzalkonium Chloride.
Polyhexanide (polyhexamethylene biguanide, PHMB) is an excellent biocide that is an environmentally friendly product and is expected to be used to provide valuable disinfection, cleaning, and hygiene functions in a broad type of products such as cosmetics, deodorant, co solutions, fabric softeners, water treatments, wound care products, and antimicrobial foam dressings.
Polyhexanide (polyhexamethylene biguanide, PHMB) is expected to be a component of pool cleaners, skin disinfectants, urinary catheter flush solutions, sanitizers in different ap hospital disinfectants, and food and equipment in contact with food.
Polyhexanide (polyhexamethylene biguanide, PHMB), polyhexanide or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
The presence of multiple hydrogen bond and chelation sites within Polyhexanide (polyhexamethylene biguanide, PHMB) renders it of potential interest in the field of supramolecular chemistry.
Polyhexanide (polyhexamethylene biguanide, PHMB) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Polyhexanide (polyhexamethylene biguanide, PHMB) is available also as a solid.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a disinfectant with a broad spectrum of inducing cell death by disrupting cell membrane integrity.
Polyhexanide (polyhexamethylene biguanide, PHMB) is an environmentally friendly, noncorrosive, and nontoxic to humans and animals.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a preservative in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a formulation based on PHMB used as sanitizer, bactericide ( antibacterial ), antiseptic and disinfectant, widely effective against positive and negative gram bacteria with applications in surface cleaners, hand cleaners / sanitizing , close to neutral powder detergent, latex polymers, antimicrobial and dishwashing liquids and other personal care applications with microbial activity.
In cosmetics, Polyhexanide (polyhexamethylene biguanide, PHMB) enables the preservation of fruit and vegetables.
Polyhexanide (polyhexamethylene biguanide, PHMB) is also used to preserve wet wipes, control odor in textiles, prevent microbial contamination in wound irrigation and sterile dressings; disinfect medical/dental utensils and trays, farm equipment, animal drinking water, and hard surfaces for food handling institutions and hospitals; and to deodorize vacuums and toilets.
Polyhexanide (polyhexamethylene biguanide, PHMB) can work at low concentrations with swift action, a broad spectrum of action, and its wide acceptance and exploitation for potential multi-purpose functional use.
Polyhexanide (polyhexamethylene biguanide, PHMB) will be promising for advanced environmental treatments, including food disinfection, water disinfection, and surface disinfection, and meet the criteria for an ideal antimicrobial agent.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a chemical biocide and a member of the polymeric guanidine family.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used as a disinfectant, antiseptic, and general disinfecting agent in the food industry and, very successfully, for the disinfection of swimming pools.
This widely used biocide has been reviewed by the US Environmental Protection Agency (EPA) and noted, except for occupational users, as having a shallow aggregate risk of adverse health effects on the public or environment.
Polyhexanide (polyhexamethylene biguanide, PHMB) binds to the negatively charged phosphate head groups of phospholipids at the bacteria cell wall, causing increased rigidity, sinking nonpolar segments into hydrophobic domains, and disrupting the membrane with subsequent cytoplasmic shedding culminating in cell death.
There have been no reported instances of bacteria acquiring resistance to Polyhexanide (polyhexamethylene biguanide, PHMB).
Polyhexanide (polyhexamethylene biguanide, PHMB) is well tolerated when used topically on skin, eyes, the ciliated epithelium of the nose, and wounds.
The market for Polyhexanide (polyhexamethylene biguanide, PHMB)-containing products, which now include liquids, gels, and antimicrobial dressings, is expanding rapidly.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a new environment-friendly cationic water-soluble polymer.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a water solution that can be used as a broad spectrum and high efficient disinfectant.
Polyhexanide (polyhexamethylene biguanide, PHMB) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexanide (polyhexamethylene biguanide, PHMB)s special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a cationic polymer with antimicrobial and antiviral properties.
Polyhexanide (polyhexamethylene biguanide, PHMB) has been commonly accepted that the antimicrobial activity is due to the ability of PHMB to perforate the bacterial phospholipid membrane leading ultimately to its death.
Polyhexanide (polyhexamethylene biguanide, PHMB) molecules attach to the surface of the phospholipid bilayer and partially penetrate it, they do not cause any pore formation at least within the microsecond simulation times.
These products have a proven track record, over many years, of use in a diverse range of hygiene products – respectively, disinfectants in the institutional, healthcare and food manufacturing industries, the household products and personal care industries, and the textile industry.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a fast-acting and broad spectrum antimicrobial, providing activity against a wide range of bacteria and viruses
Polyhexanide (polyhexamethylene biguanide, PHMB) is effective against a wide range of microorganisms, including bacteria, viruses, fungi, and algae.
Polyhexanide (polyhexamethylene biguanide, PHMB) is best known for its broad-spectrum antimicrobial and antifungal activity.
Polyhexanide (polyhexamethylene biguanide, PHMB) is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu.
Polyhexanide (polyhexamethylene biguanide, PHMB) is also used as a surface disinfectant and is alleged to be suitable for skin disinfection.
Polyhexanide (polyhexamethylene biguanide, PHMB) has a slow effectand does not meet the practical requirementsfor prophylactic antiseptics in this respect.
Although Polyhexanide (polyhexamethylene biguanide, PHMB) is somewhat less effective than benzalkonium chloride, it is sometimes used instead of benzalkonium because it is less foamproducing under use conditions.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used primarily as an antiseptic and disinfectant.
storage temp.: Inert atmosphere,Room Temperature
solubility: Water
InChI: InChI=1S/C10H23N5/c1-9(11)14-7-5-3-4-6-8-15-10(12)13-2/h3-8H2,1-2H3,(H2,11,14)(H3,12,13,15)
InChIKey: SAGIGHPRUJPLKX-UHFFFAOYSA-N
SMILES: C(=N)(C)NCCCCCCNC(=N)NC
Polyhexanide (polyhexamethylene biguanide, PHMB) is also used to preserve wet wipes; to control odor in textiles; to prevent microbial contamination in wound irrigation, sterile dressings; to deodorize vacuums and toilets; to disinfect medical/dental utensil and trays, farm equipment, animal drinking water and hard surfaces for food handling institutions and hospitals.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in antimicrobial hand washes, rubs, and air filter treatments as an alternative to ozone.
Polyhexanide (polyhexamethylene biguanide, PHMB) is also used as an active ingredient for recreational water treatment and as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.
It has been used in many applications, from swimming pool sanitizers to preservatives in cosmetics and contact lens solutions.
Clinical studies indicate it has a broad spectrum of activity, including against human immunodeficiency virus (HIV).
Polyhexanide (polyhexamethylene biguanide, PHMB) appears to be available in presentations that provide clinicians with effective wound care modalities for most clinical scenarios and has also been used as a perioperative cleansing agent in ophthalmology.
Adopt the melt polycondensation method.
Put the appropriate amount of guanidine hydrochloride and 1, 6-hexane-diamine in the polymerization kettle, stir, and raise the temperature.
After the reactants are completely melted, continue to raise the temperature, constant temperature reaction for about 2h.
And then raise the temperature to a predetermined temperature for the reaction.
After the reaction is finished, stop stirring, and pass nitrogen gas into the kettle.
Let the product flow into the pre-prepared container.
Polyhexanide (polyhexamethylene biguanide, PHMB) is usually formulated with other water treatment chemicals.
The exact formula depends on water and equipment conditions.
The recommended dosage is 100~500 mg/L when used as a separate disinfectant.
The dosage should be determined by the exact process and method if applied in textile and printing, livestock-raising, and aquaculture.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer that, in its neat form, represents a solid/powder of > 94.2 % purity, colorless, odorless, non-corrosive, and non-irritating antimicrobial biocide.
Polyhexanide (polyhexamethylene biguanide, PHMB) has a good water solubility of around 40 %.
It is also soluble in alcohol and used as a common solvent for paints and lacquers.
Average molecular weights range between 2670 and 4216 Da.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a positively charged polymer having polymeric biguanide units in the backbone of its structure [−(CH2)6.NH.C(=NH). NH.C(=NH).NH-]n, where n ranges from 2 to 40, having an average value of 11.
Polyhexanide (polyhexamethylene biguanide, PHMB) is as good a metal chelator as its parent molecule, biguanide; the five conjugated amines, when binding to neighboring molecules with multiple hydrogen bonds, will be attractive for supra molecular chemistry.
Films of Polyhexanide (polyhexamethylene biguanide, PHMB) are transparent and very adhesive to metal, plastics, and glass.
It is a proton conductor, potentially applicable to proton exchange membrane fuel cells.
The infrared absorption spectrum of Polyhexanide (polyhexamethylene biguanide, PHMB) showed that the most important are those located at the 2,000–2,400 nm range, corresponding to nitrogen-related vibrations, including combination bands due to nitrogen-carbon bonds in the biguanide pseudoaromatic ring.
Polyhexanide (polyhexamethylene biguanide, PHMB) is recognized as the safest and the most efficient broad-spectrum antibacterial agent in the 21st century.
Polyhexanide (polyhexamethylene biguanide, PHMB) is colorless and tasteless, low bacterial inhibition concentration, broad spectrum, low toxicity.
Polyhexanide (polyhexamethylene biguanide, PHMB) can form a layer of cations on the surface of article, which can inhibit bacteria for a long time.
Polyhexanide (polyhexamethylene biguanide, PHMB) also has no bacteria drug resistance.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a broad‐spectrum antimicrobial substance used as a preservative in many products.
These products have a proven track record, over many years, of use in a diverse range of hygiene products – respectively, disinfectants in the institutional, healthcare and food manufacturing industries, the household products and personal care industries, and the textile industry.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a fast-acting and broad spectrum antimicrobial, providing activity against a wide range of bacteria and viruses
Polyhexanide (polyhexamethylene biguanide, PHMB) performs a high activity and the polymer itself is cationic.
Since bacteria and viruses are usually anionic, they are easy to be absorbed by Polyhexanide (polyhexamethylene biguanide, PHMB) and could not divide and reproduce, and finally turn inactive.
Polyhexanide (polyhexamethylene biguanide, PHMB) collapses the cell membrane structure and forms transmembrane stomata.
Ultimately, Polyhexanide (polyhexamethylene biguanide, PHMB) causes cell membrane rupture, disrupts the energy metabolism of the organism, and disables bacteria and viruses.
The polymer forms a film that closes off the breathing passages of microorganisms, causing them to suffocate and die.
The sterilization mechanism is independent of the form and type of microorganisms.
Even if the microorganisms mutate, the mutation will not affect their efficacy.
Microorganisms do not produce resistance to Polyhexanide (polyhexamethylene biguanide, PHMB).
Uses Of Polyhexanide (polyhexamethylene biguanide, PHMB):
Polyhexanide (polyhexamethylene biguanide, PHMB) can be found in surface disinfectants, bathroom cleaners, and other household disinfecting sprays to kill bacteria and viruses on surfaces.
In addition to personal care products, Polyhexanide (polyhexamethylene biguanide, PHMB) is used in cosmetics to prevent microbial contamination and extend product shelf life.
Polyhexanide (polyhexamethylene biguanide, PHMB) may be included in formulations such as makeup removers, facial cleansers, and other cosmetic products where preservation is important.
Polyhexanide (polyhexamethylene biguanide, PHMB) finds applications in agriculture for crop protection and preservation.
Polyhexanide (polyhexamethylene biguanide, PHMB) may be used in formulations to control microbial growth on seeds, plant surfaces, and agricultural equipment, helping to prevent diseases and improve crop yields.
Polyhexanide (polyhexamethylene biguanide, PHMB)-coated medical devices are increasingly being developed to prevent microbial colonization and reduce the risk of device-related infections.
These may include catheters, implants, and surgical instruments where antimicrobial protection is critical.
Polyhexanide (polyhexamethylene biguanide, PHMB) can be used in mold remediation products to inhibit the growth of mold and mildew on surfaces, particularly in damp or humid environments where mold growth is a concern.
Polyhexanide (polyhexamethylene biguanide, PHMB) is sometimes used as a preservative in pharmaceutical formulations to prevent microbial contamination and maintain product stability.
In addition to its use as a standalone antimicrobial agent, Polyhexanide (polyhexamethylene biguanide, PHMB) may also be incorporated into formulations with other biocides to enhance antimicrobial efficacy across a broader spectrum of microorganisms.
These various applications highlight the versatility and effectiveness of PHM
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in various healthcare products for its antiseptic and antimicrobial properties.
Polyhexanide (polyhexamethylene biguanide, PHMB) helps prevent infections and promotes wound healing.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used to treat minor cuts, burns, and abrasions.
Polyhexanide (polyhexamethylene biguanide, PHMB) is included in multipurpose solutions to disinfect and clean contact lenses.
Polyhexanide (polyhexamethylene biguanide, PHMB) is found in many personal care products for its antimicrobial benefits.
Polyhexanide (polyhexamethylene biguanide, PHMB) helps control the growth of bacteria and fungi on the skin.
Polyhexanide (polyhexamethylene biguanide, PHMB) prevents microbial contamination and maintains product freshness.
Polyhexanide (polyhexamethylene biguanide, PHMB) may be included in creams, lotions, and gels to inhibit the growth of harmful microorganisms.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in textile finishing treatments to impart antimicrobial properties to fabrics.
This is particularly important in healthcare settings, where textiles such as hospital gowns, bed linens, and curtains need to be hygienic and resistant to microbial growth.Polyhexanide (polyhexamethylene biguanide, PHMB) is employed as a disinfectant in swimming pools, spas, and water purification systems.
Polyhexanide (polyhexamethylene biguanide, PHMB) effectively controls microbial growth, including bacteria and algae, to ensure water safety and clarity.
Polyhexanide (polyhexamethylene biguanide, PHMB) is used in various industrial processes where microbial contamination needs to be controlled.
Polyhexanide (polyhexamethylene biguanide, PHMB) helps prevent microbial growth and deterioration of coatings.
Polyhexanide (polyhexamethylene biguanide, PHMB) ensures product integrity by inhibiting microbial contamination.
Other industrial applications where microbial control is necessary for product quality and safety.
Broad spectrum antimicrobial polymer; binds and disrupts cytoplasmic membranes.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic.
In dermatological use, Polyhexanide (polyhexamethylene biguanide, PHMB) is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide.
Polyhexanide (polyhexamethylene biguanide, PHMB) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).
Polyhexanide (polyhexamethylene biguanide, PHMB), is a synthetic polymer that is used in a variety of consumer and industrial products, including wet wipes.
Polyhexanide (polyhexamethylene biguanide, PHMB) is an antimicrobial agent that kills or inhibits the growth of bacteria, fungi, and other microorganisms.
Polyhexanide (polyhexamethylene biguanide, PHMB) is also effective against a wide range of viruses, including influenza and hepatitis.
Polyhexanide (polyhexamethylene biguanide, PHMB) has been used in wet wipes for many years and is considered to be safe and effective.
Polyhexanide (polyhexamethylene biguanide, PHMB) can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.
Polyhexanide (polyhexamethylene biguanide, PHMB) is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a kind of broad-spectrum antibacterial agent recognized as the safest and most efficient in the 21st century.
Polyhexanide (polyhexamethylene biguanide, PHMB) is colorless and odorless, has low bacteriostatic concentration, broad-spectrum and low toxicity, fast action, low foam volume, and can After forming a layer of cations on the surface of the article for a long time, it will not cause bacteriostasis, and it will not cause antibacterial bacteria.
Polyhexanide (polyhexamethylene biguanide, PHMB) is currently widely used in medical devices, public environments, home, fabrics, food, milk, and care products.
Polyhexanide (polyhexamethylene biguanide, PHMB) is widely used in medical and health, daily chemicals, textiles, paper, wet wipes, animal husbandry, breeding, aquatic products, plastics, agriculture, water treatment and other fields.
Polyhexanide (polyhexamethylene biguanide, PHMB) formulations help maintain hygiene and prevent skin infections in pets and livestock.
Polyhexanide (polyhexamethylene biguanide, PHMB) is incorporated into household cleaning products for its antimicrobial properties.
Safety Profile Of Polyhexanide (polyhexamethylene biguanide, PHMB):
Polyhexanide (polyhexamethylene biguanide, PHMB) is important to use protective gloves and avoid direct skin contact when handling concentrated PHMB solutions.
Contact with PHMB can cause irritation to the eyes.
In case of eye exposure, it is essential to rinse the eyes thoroughly with water and seek medical attention if irritation persists.
Inhalation of Polyhexanide (polyhexamethylene biguanide, PHMB) dust or mist may cause respiratory irritation or discomfort.
Adequate ventilation should be ensured in areas where Polyhexanide (polyhexamethylene biguanide, PHMB) is handled, and respiratory protection may be necessary when working with powdered forms of PHMB.
Polyhexanide (polyhexamethylene biguanide, PHMB) is generally considered low in toxicity, high concentrations or ingestion of PHMB solutions can be harmful.
Ingestion of Polyhexanide (polyhexamethylene biguanide, PHMB) may cause gastrointestinal irritation, nausea, vomiting, and other adverse effects.
Polyhexanide (polyhexamethylene biguanide, PHMB) is essential to store PHMB products securely and keep them out of reach of children and pets.
On the 20th of April 2018, the european commission decided to ban preservative uses of Polyhexanide (polyhexamethylene biguanide, PHMB) PT9 (Fibre, leather, rubber and polymerised materials preservatives).
Polyhexanide (polyhexamethylene biguanide, PHMB)’s still allowed for uses as disinfectants PT2 (Disinfectants and algaecides not intended for direct application to humans or animals).
In 2011, Polyhexanide (polyhexamethylene biguanide, PHMB) was classified as category 2 carcinogen by the European Chemical Agency, but it is still allowed in cosmetics in small quantities if exposure by inhalation is impossible.
Polyhexanide (polyhexamethylene biguanide, PHMB) can cause skin irritation or sensitization, particularly in individuals with sensitive skin or those who are exposed to concentrated solutions for prolonged periods.
