POLYOXYETHYLENE (20) SORBITAN TRIOLEATE

Polyoxyethylene (20) sorbitan trioleate is widely used as emulsifier, dispersant, stabilizer, dispersing agent, softening agent, antistatic agent, finishing agent in industries such as food, medicine, cosmetics, paint and textile, and used as anti-rust agent in metal surface rust cleaning industry, meanwhile it is also used as the viscosity reducer for oil exploitation and transportation.
Polyoxyethylene (20) sorbitan trioleate is used as stabilizer and foaming agent in the production of polyurethane foam plastics.

CAS Number: 9005-70-3
EC Number: 618-422-4
MDL Number: MFCD01779641
IUPAC Name: Polyoxyethylene (20) sorbitan monolaurate
Molecular Formula: C58H114O26
Molar Mass: 1226 g/mol

SYNONYMS:
Tween 20, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate, Kolliphor PS 20, Montanox 20, Alkest TW 20, Kotilen-20, Scattics, Polyoxyethylene (20) sorbitan trioleate, Polysorbate 85, Sorbitan trioleate, polyoxyethylene derivatives, Surfactant T85, Polysorbate 85, RefChem:8972, Tween 85, A7F3N56197, ALKAMULS PSTO-20, CCRIS 703, Emsorb 6903, Glycosperse TO-20, JEESORB TO-20, Liposorb TO-20, POLYOXYETHYLENE 20 SORBITAN TRIOLEATE (COMPOUND USUALLY CONTAINS ALSO ASSOCIATED FATTY ACIDS), POLYOXYETHYLENE SORBITAN TRIOLEATE (20E.O.), Polyoxyethylene (20) sorbitan trioleate, Polyoxyethylene 20 sorbitan trioleate, Protasorb TO-20, SORBAX PTO-20, SORBON T-85, Sorbimacrogol trioleate 300, Sorbitan, tri-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs., Sorbitan, trioleate polyoxyethylene deriv., UNII-A7F3N56197, 85, Tween-85, Tween?85, Tween 85, protasorbto-20, Polysorbate 85, Emulsifier T-85, sorbimacrogoltrioleate300, tween(R) 85 250-450 mpa.S, polyoxyethylene20sorbitaltrioleate, Polyoxyethylene (20) Sorbitan Trioleate, sorbitan,trioleatepolyoxyethylenederiv., tri-9-octadecenoate,poly(oxy-1,2-ethanediyl)derivs.,(z,z,z)-sorbita, tri-9-octadecenoate,poly(oxy-1,2-ethanediyl)derivs.,(Z,Z,Z)-Sorbitan, Polyethylene glycol sorbitan trioleate, Polyoxyethylene sorbitantrioleate, Polyoxyethylene (20) sorbitan trioleate, Polyoxyethylenesorbitan Trioleate, glycosperse TO-20, hetsorb TO-20, liposorb TO-20, lonzest STO-20, monebat - 85, nikkol TO-30V, poe-20 sorbitan trioleate, polyethyleneglycol sorbitan trioleate, polyoxyethylene (20) sorbitan trioleate, protasorb TO-20, rheodol TW-O320V, toximul see-340, tween 85

Polyoxyethylene (20) sorbitan trioleate is an anionic surfactant manufactured by addition polymerization of ethylene oxide to sorbitan trioleate.
Polyoxyethylene (20) sorbitan trioleate is a high safety surfactant, and disperses in water and dissolves in oil.

Polyoxyethylene (20) sorbitan trioleate, also known as polyoxyethylene sorbitan trioleate, is a kind of oily liquid from yellow to amber under room temperature.
Polyoxyethylene (20) sorbitan trioleate will become gel when temperature drop and liquefy again when temperature rise, with special odor.

Polyoxyethylene (20) sorbitan trioleate, commonly known as Polysorbate 85, is a non-ionic surfactant widely used in pharmaceuticals, food products, and cosmetics due to its emulsifying and solubilizing properties.
Polyoxyethylene (20) sorbitan trioleate is synthesized from sorbitol and oleic acid, with an average of 20 ethylene oxide units per molecule.

Polyoxyethylene (20) sorbitan trioleate has a molecular formula of C60H108O8 and an HLB (Hydrophilic-Lipophilic Balance) value of approximately 15-16, indicating its hydrophilic nature suitable for oil-in-water emulsions.
Polyoxyethylene (20) sorbitan trioleate is soluble in water, methanol and ethanol, insoluble in mineral oil, used as emulsifier, dispersant, wetting agent, solubilizer and stabilizer.

Polyoxyethylene (20) sorbitan trioleate is a light yellow oily object at room temperature, slightly bitter, soluble in water, aniline, ethyl acetate and toluene, insoluble in mineral oil and vegetable oil.
With wetting, foaming, diffusion and other properties, Polyoxyethylene (20) sorbitan trioleate is an O/W type emulsifier, HLB value of 15.

Polyoxyethylene (20) sorbitan trioleate is a sorbitan fatty acid ester ethoxylate and is recommended as an emulsifier for mineral oils.
Polyoxyethylene (20) sorbitan trioleate is suitable for use as an inert ingredient in combination with permitted active pesticidal ingredients according to US NOP.

USES and APPLICATIONS of POLYOXYETHYLENE (20) SORBITAN TRIOLEATE: 
Polyoxyethylene (20) sorbitan trioleate series is widely used in food, medicine and cosmetics industries as emulsifier, stabilizer, thickening agent and wetting agent,as well as applied in many other industries.
Pharmaceuticals : Polyoxyethylene (20) sorbitan trioleate is used in injectable formulations to solubilize lipophilic drugs and stabilize emulsions.

Cosmetics : Polyoxyethylene (20) sorbitan trioleate acts as an emulsifier in creams and lotions to maintain consistency.
Food Industry : Polyoxyethylene (20) sorbitan trioleate functions as an emulsifier to improve texture and prevent separation in products like sauces and dressings.

Veterinary Medicine : Polyoxyethylene (20) sorbitan trioleate is utilized in injectable vaccines for pets and livestock to enhance drug solubility.
Polyoxyethylene (20) sorbitan trioleate is a kind of O/W emulsifier.

Polyoxyethylene (20) sorbitan trioleate is widely used as emulsifier, dispersant, stabilizer, dispersing agent, softening agent, antistatic agent, finishing agent in industries such as food, medicine, cosmetics, paint and textile, and used as anti-rust agent in metal surface rust cleaning industry, meanwhile it is also used as the viscosity reducer for oil exploitation and transportation.

Polyoxyethylene (20) sorbitan trioleate is used as stabilizer and foaming agent in the production of polyurethane foam plastics.
Polyoxyethylene (20) sorbitan trioleate can be used as antistatic agent in synthetic fiber, and is the intermediate of chemical fiber oil agent.

Polyoxyethylene (20) sorbitan trioleate is used as wetting agent and dispersing agent in photographic film making.
Polyoxyethylene (20) sorbitan trioleate is used as emulsifier, stabilizer, wetting agent, diffusing agent, penetrating agent

Polyoxyethylene (20) sorbitan trioleate is used as an emulsifier in pesticides, pharmaceuticals, foods and cosmetics, and also as an emulsifier in various O/W emulsions.
In the textile industry, Polyoxyethylene (20) sorbitan trioleate is used as oils and lubricants.

As an emulsifier, Polyoxyethylene (20) sorbitan trioleate is frequently used in combination with span 80.
Polyoxyethylene (20) sorbitan trioleate is widely used in oil exploration and transportation, medicine, cosmetics, paint, pigments, textiles, food, pesticides, in the production of detergent and metal surface corrosion inhibitor and cleaning agent.

Polyoxyethylene (20) sorbitan trioleate is used as emulsifier, softener, finishing agent, viscosity reducer, etc.
Polyoxyethylene (20) sorbitan trioleate is used as emulsifier, stabilizer, wetting agent, diffusing agent, penetrant, etc.
In the process of fabric waterproofing to emulsify silicone oil, Polyoxyethylene (20) sorbitan trioleate has a good effect, also used in nylon and viscose cord as oil agent and water-soluble emulsifier, often mixed with S-80.

Polyoxyethylene (20) sorbitan trioleate is used as oil field emulsifier, paraffin inhibitor, heavy oil wetting agent, drag reduction agent and near-well zone treatment agent.
Polyoxyethylene (20) sorbitan trioleate is used as the lubricating coolant for precision machine tools.

Polyoxyethylene (20) sorbitan trioleate, commercially known as Tween 85, is a nonionic surfactant widely employed in various scientific research fields.
Polyoxyethylene (20) sorbitan trioleate belongs to the polysorbate family and plays a crucial role in forming microemulsions, solubilizing compounds, stabilizing dispersions, and modifying interfaces.

Polyoxyethylene (20) sorbitan trioleate is a nonionic surfactant and emulsifier derived from sorbitol.
Polyoxyethylene (20) sorbitan trioleate's chemical structure consists of a sorbitan backbone esterified with three oleic acid chains (C18:1) and conjugated with polyoxyethylene (POE) groups (typically 20 ethylene oxide units) .

The CAS number is 9005-70-3, and Polyoxyethylene (20) sorbitan trioleate's molecular formula is C₆₀H₁₀₈O₈·(C₂H₄O)ₙ .
Polyoxyethylene (20) sorbitan trioleate is characterized by its lipophilic nature, making it suitable for stabilizing water-in-oil emulsions and enhancing drug solubility in pharmaceutical formulations .

-Food Industry uses of Polyoxyethylene (20) sorbitan trioleate:
Polyoxyethylene (20) sorbitan trioleate is extensively used in the food industry for its emulsifying and stabilizing properties.
In a study, it was found that Polyoxyethylene (20) sorbitan trioleate effectively enhances the dispersion of flavoring agents in beverages, ensuring uniform taste throughout the product.

-Pharmaceutical Applications of Polyoxyethylene (20) sorbitan trioleate:
In pharmaceuticals, Polyoxyethylene (20) sorbitan trioleate is utilized for its solubilizing and stabilizing properties in drug formulations.
Research indicates that Polyoxyethylene (20) sorbitan trioleate plays a critical role in maintaining the stability of protein structures in biopharmaceuticals, preventing aggregation during storage.

-Cosmetic Industry uses of Polyoxyethylene (20) sorbitan trioleate: 
In cosmetics, Polyoxyethylene (20) sorbitan trioleate serves as an emulsifier and solubilizer.
Polyoxyethylene (20) sorbitan trioleate is particularly effective in improving the consistency of formulations and preventing separation over time.

-Industrial Applications of Polyoxyethylene (20) sorbitan trioleate:
Polyoxyethylene (20) sorbitan trioleate is also used in various industrial applications due to its emulsifying properties.
In industrial cleaning products, Polyoxyethylene (20) sorbitan trioleate helps dissolve oils and dirt effectively, improving cleaning efficiency.

-Scientific and Pharmaceutical
Polyoxyethylene (20) sorbitan trioleate is used in immunoassays (e.g., Western blots, ELISAs) to prevent non-specific antibody binding.
Polyoxyethylene (20) sorbitan trioleate serves as a solubilizing agent for membrane proteins.

Polyoxyethylene (20) sorbitan trioleate stabilizes proteins in solutions, such as purified protein derivatives used in tuberculosis skin testing.
Polyoxyethylene (20) sorbitan trioleate aids in lysing mammalian cells in laboratory settings.

-Food and Consumer Products
Polyoxyethylene (20) sorbitan trioleate acts as a wetting agent in flavored mouth drops, facilitating the spreading of ingredients like alcohol and mint flavor.
Polyoxyethylene (20) sorbitan trioleate is incorporated into baby wipes and other personal care products.
Polyoxyethylene (20) sorbitan trioleate is utilized in the elastomer industry as a wetting agent in rubber balers.

-Industrial and Miscellaneous
Polyoxyethylene (20) sorbitan trioleate is employed by philatelists to remove stamps from envelopes and to clean residues without damaging the stamps.
Polyoxyethylene (20) sorbitan trioleate is used as a shape-directing agent in the synthesis of spheroidal magnetite nanoassemblies.

-Cosmetics and Personal Care uses of Polyoxyethylene (20) sorbitan trioleate:
*Emulsifier: 
Polyoxyethylene (20) sorbitan trioleate facilitates the blending of oil and water phases in formulations such as lotions, creams, and shampoos.

*Solubilizer: 
Polyoxyethylene (20) sorbitan trioleate is incorporates essential oils and fragrances into aqueous-based products, preventing separation.

*Foam Enhancer: 
Polyoxyethylene (20) sorbitan trioleate contributes to the formation and stability of foam in cleansing products.

*Skin and Hair Care: 
Polyoxyethylene (20) sorbitan trioleate is utilized in face washes, baby products, and hair care items due to its gentle nature.

-Pharmaceuticals uses of Polyoxyethylene (20) sorbitan trioleate:
*Drug Formulation: 
Polyoxyethylene (20) sorbitan trioleate acts as an excipient to stabilize emulsions and suspensions, ensuring uniform distribution of active ingredients.

*Protein Stabilization: 
Polyoxyethylene (20) sorbitan trioleate prevents aggregation and denaturation of proteins in injectable formulations.

-Food Industry uses of Polyoxyethylene (20) sorbitan trioleate:
*Emulsifier: 
Polyoxyethylene (20) sorbitan trioleate is incorporated into products like salad dressings, cake mixes, and ice cream to maintain consistency.

*Flavor Carrier: 
Polyoxyethylene (20) sorbitan trioleate enhances the dispersion of flavors and essential oils in food products.

*Preservative: 
Polyoxyethylene (20) sorbitan trioleate extends shelf life by preventing microbial growth in certain formulations.

-Biotechnology and Laboratory uses of Polyoxyethylene (20) sorbitan trioleate:
*Immunoassays: 
Polyoxyethylene (20) sorbitan trioleate is used in techniques like Western blotting and ELISA to reduce nonspecific binding of antibodies.

*Protein Solubilization: 
Polyoxyethylene (20) sorbitan trioleate assists in the extraction and stabilization of membrane proteins.

*Cell Lysis: 
Polyoxyethylene (20) sorbitan trioleate facilitates the breakdown of cell membranes in research applications.

-Industrial Applications of Polyoxyethylene (20) sorbitan trioleate:
*Rubber Industry: 
Polyoxyethylene (20) sorbitan trioleate serves as a wetting agent in rubber balers.

*Stamp Collection: 
Polyoxyethylene (20) sorbitan trioleate is employed by philatelists to remove stamps from envelopes without damage.