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POLYOXYETHYLENE (20) SORBITAN TRISTEARATE (POLYSORBATE 65)

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is part of the polysorbate family, similar to Polysorbate 20 and Polysorbate 80, but it has a unique chemical structure and is used in specific applications.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65), is an ingredient made from sorbitol, stearic acid (C18) and ethylene oxide.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is primarily used as an emulsifier in food (the European food additive number E435) and a solubilizer & surfactant in cosmetics.

CAS Number: 9005-71-4
EINECS Number: 500-019-9

Synonyms: Polysorbate 65, Tween 65, 14BGY2Y3MJ, Peg-20 sorbitan tristearate, Polyoxyethylene (20) sorbitan tristearate, DTXSID30891988, E-436, Emsorb 6907, Glycosperse TS 20, INS NO.436, INS-436, JEESORB STS-20, LIPOSORB TS-20, NIKKOL TS-30, POLYSORBATE 65 (II), Peg sorbitan tristearate, SORBAX PTS-20, Sorbimacrogol tristearate 300, Sorbitan, tristearate, polyoxyethylene derivs., UNII-14BGY2Y3MJ, Polysprbate65;Tween 65 Polysorbate 65;POE20;POLYETHYLENEGLYCOLSORBITANTRISTEARATE;POLYOXYETHYLENE-1,4-SORBITAN-TRISTEARATE;Sorbitantristearat, EO 20 mol;POLYOXYETHYLENE(20) SORBITAN TRISTEARATE(TWEEN (R) 65);Ahco 7166T

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65), consists of sorbitol, ethylene oxide, and stearic acid.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in a variety of products including skin fresheners, skin care products, skin cleansing products, makeup bases and foundations, shampoos, permanent waves and fragrance powders.
The Polysorbate ingredients help other ingredients to dissolve in a solvent in which they would not normally dissolve.

They also help to form emulsions by reducing the surface tension of the substances to be emulsified.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a nonionic surfactant and emulsifying agent. 
Like other polysorbates, the number 65 after polysorbate means the type of fatty acid, here is monostearate; the number 20 following polyoxyethylene indicates the total number of oxyethylene groups in the molecule structure.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is Soluble in water
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is insoluble in mineral oil and vegetable oils.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is Soluble in ethyl acetate and toluene.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65), is an ingredient made from sorbitol, stearic acid (C18) and ethylene oxide.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is primarily used as an emulsifier in food (the European food additive number E435) and a solubilizer & surfactant in cosmetics.
Like other polysorbates, the number 60 after polysorbate means the type of fatty acid, here is monostearate; the number 20 following polyoxyethylene indicates the total number of oxyethylene groups in the molecule structure.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a mixture of stearate esters of sorbitol and sorbitol anhydrides Polysorbate 65 or Tween 65 is the abbreviation of “polyoxyethylene (20) sorbitan”.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a surfactant type polysorbate whose stability and relative non-toxicity allow it to be used as a detergent and emulsifier in the food, industrial, cosmetic, and pharmaceutical industries.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is surfactants that are produced by reacting the polyol, sorbitol, with ethylene oxide.

The number in the name of the Polysorbate indicates the average number of moles of ethylene oxide that has been reacted per mole of sorbitol.
The polyoxyethylenated sorbitan is then reacted with fatty acids obtained from vegetable fats and oils such as lauric acid, palmitic acid, stearic acid and oleic acid.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is function to disperse oil in water as opposed to water in oil Polysorbate 65 is a synthetically produced emulsifier and dispersing agent used to carry flavors and colors in foods.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is considered safe and has no adverse effects reported at the levels present in food.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) may aggravate propylene glycol sensitivity
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) consists of a sorbitan (sorbitol) backbone esterified with tristearic acid (a fatty acid), which is then reacted with ethylene oxide to form a polyoxyethylene chain, typically with 20 ethylene oxide units.

The structure is characterized by the attachment of the stearate (tristearic acid) groups to the sorbitol molecule and the Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) attached to the sorbitan group.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) helps to stabilize emulsions, which are mixtures of water and oil-based ingredients. 
It lowers the surface tension between the two phases, ensuring that they do not separate.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) functions as a surfactant, reducing the surface tension between liquids, which allows for better spreading and dispersion of the product.
It aids in dissolving hydrophobic compounds (such as oils and fragrances) in water-based solutions, improving the solubility of various substances.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in creams, lotions, and ointments to stabilize emulsions and improve the texture and application of the product.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is found in shampoos, conditioners, and hair treatments to disperse oils and conditioners evenly throughout the formulation.
It is used in cosmetic products such as foundations and mascaras to help achieve a smooth texture and even distribution of ingredients.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in pharmaceutical formulations to enhance the solubility of poorly water-soluble drugs, improving bioavailability and stability.

Flash point: 149 °C
storage temp.: Store at RT.
Hydrophilic-Lipophilic Balance (HLB): 10.5

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in ointments and creams to ensure that active ingredients are uniformly distributed and efficiently absorbed.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in food products, particularly in products like sauces, dressings, and margarine, to help mix water and oil components and maintain product consistency.
It may be used in cell culture applications to stabilize hydrophobic molecules or improve the delivery of certain nutrients or growth factors.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) may also be used in industrial formulations like paints and coatings to help emulsify oils and improve spreading characteristics.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is considered safe for use in food and cosmetics at regulated concentrations. 
The FDA has approved its use as an emulsifier and stabilizer in food products within specific limits.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is generally non-toxic, but like other emulsifiers, it may cause mild skin or eye irritation in some sensitive individuals. 
As with any cosmetic or pharmaceutical product, patch testing is recommended for those with sensitive skin.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is biodegradable, but in large quantities, it could have an impact on aquatic ecosystems. 

Proper disposal practices should be followed to minimize environmental damage.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) helps water-based and oil-based ingredients blend easily and prevent their separation in food.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) and 80 are mostly used in food among the category of polysorbates, but the latter is used more than 60 in food.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65)'s general purpose in cosmetics is to mix water and oil together.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) functions as a surfactant, emulsifier, solubilizer and dispersing agent.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) Helps wash away body dirties by lowering the surface tension on the skin when used in shampoos and body washes.

Distribute essential oils, fragrances and colorants evenly in water.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a mid-range HLB, nonionic surfactant suggested for use in textile chemicals (lubricant, emulsifier), household products (o/w emulsifier) and cosmetic formulations (o/w emulsifier).
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used as an emulsifier. Suggested applications: ice cream, cakes and cake icings

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is an emulsifier manufactured by reacting stearic acid with sorbitol to yield a product which is then reacted with ethylene oxide.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a nonionic surfaceactive agent which is dispersible in fat, oil, and water.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is also termed polysorbate 65.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in frozen desserts, cakes, and coffee whiteners.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is frequently used with sorbitan monostearates or monoand diglycerides
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a synthetically produced emulsifier and dispersing agent used to carry flavors and colors in foods.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is considered safe and has no adverse effects reported at the levels present in food.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) may aggravate propylene glycol sensitivity.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a class of emulsifiers used in some pharmaceuticals and food preparation.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is often used in cosmetics to solubilize essential oils into water-based products.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is oily liquids derived from ethoxylated sorbitan.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is an emulsifier manufactured by reacting stearic acid with sorbitol to yield a product which is then reacted with ethylene oxide.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a nonionic surfaceactive agent which is dispersible in fat, oil, and water.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in frozen desserts, cakes, and coffee whiteners.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is frequently used with sorbitan monostearates or monoand diglycerides.

Uses:
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used as an emulsifier. 
Suggested applications: ice cream, cakes and cake icings. Product Data Sheet
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is an emulsifier manufactured by reacting stearic acid with sorbitol to yield a product which is then reacted with ethylene oxide. 

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a nonionic surfaceactive agent which is dispersible in fat, oil, and water. 
It is also termed polysorbate 65. 
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in frozen desserts, cakes, and coffee whiteners. 

It is frequently used with sorbitan monostearates or monoand diglycerides. 
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is a mid-range HLB, nonionic surfactant suggested for use in textile chemicals (lubricant, emulsifier), household products (o/w emulsifier) and cosmetic formulations (o/w emulsifier).
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is commonly used in creams, lotions, ointments, and other skincare products to help mix oil and water-based ingredients, forming stable emulsions.

It is found in shampoos, conditioners, hair treatments, and styling products, where it helps distribute oils and conditioners evenly, improving texture and manageability.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in makeup formulations, such as foundations, mascaras, and lipsticks, to help achieve smooth texture and even distribution of pigments and other active ingredients.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in sunscreens and anti-aging treatments to ensure active ingredients are evenly dispersed throughout the product.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in pharmaceutical formulations to help solubilize poorly water-soluble drugs, improving their bioavailability. 
This makes it useful in oral and injectable drug products.
It is included in creams, gels, and ointments to aid in the dispersion of active ingredients, ensuring uniform application and absorption on the skin.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) can also be used in drug delivery systems to enhance the stability and effectiveness of certain medications, particularly those that involve hydrophobic molecules.
It is widely used in food products like sauces, salad dressings, margarine, ice cream, and beverages to prevent the separation of oil and water, stabilizing emulsions.
In processed foods, Polysorbate 65 helps improve the texture, smoothness, and mouthfeel of products like whipped toppings, creamers, and spreads.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used to solubilize flavor oils, essential oils, and fragrances, ensuring even distribution of these compounds in food and beverages.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in laboratory and industrial cell cultures to stabilize hydrophobic substances and improve nutrient delivery.
It helps stabilize proteins in biologic formulations and vaccines, preventing aggregation and improving the shelf life of these products.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in the production of paints and coatings, where it helps emulsify oils and improve the spreading properties of the product.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) can be found in industrial cleaning formulations where it helps remove oils and dirt from surfaces by emulsifying them into the solution.
It is included in pesticide and herbicide formulations to help disperse the active ingredients more effectively across plant surfaces.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) can be used in fertilizers to improve the even distribution of nutrient ingredients.
It may be used in animal feed formulations to help incorporate fat-soluble vitamins and other nutrients into the feed mix.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in perfumes, room sprays, and air fresheners to help solubilize and disperse essential oils and fragrance compounds in water-based formulations.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in household and industrial cleaning products, including laundry detergents, dishwashing liquids, and surface cleaners. 
It helps to emulsify oils and grease, allowing them to be washed away effectively with water.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in fabric softeners to help distribute the softening agents evenly across fabrics, resulting in a smoother feel and improved manageability of clothes.

It can be included in textile processing as an emulsifier or dispersing agent to aid in the application of dyes and finishing chemicals, helping them adhere evenly to fabric surfaces.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is used in metalworking fluids as an emulsifier to create stable oil-in-water emulsions that help lubricate and cool machinery during operations like cutting, grinding, and machining.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) can be found in furniture, car, and floor polishes, where it helps emulsify the oils and waxes, making the polishing process smoother and more effective.

Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is sometimes used in agricultural sprays (insecticides, fungicides) to improve the spread and adherence of the active ingredients to plant surfaces, ensuring better coverage and effectiveness.
In foliar feed and other agricultural products, Polysorbate 65 helps emulsify oils or act as a stabilizer for liquid fertilizers, making them more effective when sprayed onto plants.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) can be used in water treatment plants as an emulsifier or to enhance the performance of coagulants and flocculants in purifying water. 

It helps to disperse additives in the water, improving the efficiency of the treatment process.
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) can be used in industrial water systems where foam formation is problematic, such as in cooling towers and chemical processing plants, to reduce foam and improve system efficiency.

Safety Profile:
Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is generally considered non-toxic in low concentrations and has a low potential for causing acute toxicity. 
It is commonly used in food, cosmetics, and pharmaceuticals without significant risk of harm at regulated levels.
If ingested in large amounts, it could cause gastrointestinal discomfort, such as nausea, diarrhea, or abdominal pain. 

However, ingestion in the quantities typically found in consumer products is unlikely to pose a serious risk.
While Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is usually non-irritating to the skin in most formulations, it can cause mild irritation or sensitization in some individuals, particularly if used in higher concentrations or on sensitive skin.

Contact with eyes can cause mild irritation, such as redness or discomfort. 
If irritation occurs, Polyoxyethylene (20) sorbitan tristearate (Polysorbate 65) is recommended to rinse the eyes with water immediately.


 

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