Quick Search
CAS NUMBER: 9004-99-3
EC NUMBER: 244-754-0
MOLECULAR FORMULA: C20H40O3
MOLECULAR WEIGHT: 328.53
Polyoxyethylene (40) stearate is a neutral surfactant.
Polyoxyethylene (40) stearate is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier.
Polyoxyethylene (40) stearate is a mixture of polyethylene glycol esters.
Polyoxyethylene (40) stearate is compatible with lipophilic compounds due to a higher free fatty acid content.
Polyoxyethylene (40) stearates are esters of polyethylene glycol and stearic acid.
Polyoxyethylene (40) stearates are soft to waxy solids that are white to tan in color.
In cosmetics and personal care products, Polyoxyethylene (40) stearates are used in skin creams, conditioners, shampoos, body cleansers and soapless detergents.
Polyoxyethylene (40) stearate is used in cosmetics and beauty products primarily as a surfactant and cleansing agent, because PEG Stearates' ability to clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
Polyoxyethylene (40) stearate is also seen as an emollient, because of secondary properties.
Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
Polyoxyethylene (40) stearate has also been used in a study to investigate its effects on multidrug resistance (MDR).
Polyoxyethylene (40) stearate is a non-ionic surfactant, which is permitted for use as the E number food additive E431.
Polyoxyethylene (40) stearate is a high molecular weight, high HLB surface active agent suggested for use in cosmetic formulations.
Polyoxyethylene (40) stearate is a multifunctional surface active agent suggested for use in cosmetic formulations, household products, lubricants, textile chemicals, polishes and paper.
Polyoxyethylene (40) stearate is listed as particularly applicable for hand and body lotions and creams.
Polyoxyethylene (40) stearate is an emulsifier and antifoaming agent used in processed foods, fruit jellies, and sauces.
Polyoxyethylene (40) stearate is a mixture of the monoand diesters of stearic acid and mixed polyoxyethylene diols having an average polymer length.
Polyoxyethylene (40) stearate corresponds to the average number of ethylene oxide monomers in the polyethylene chain (from 2 - 150).
Polyoxyethylene (40) stearate is not considered to be an irritant or sensitizer (it gave only minimal irritation in studies up to 100%), and are CIR and FDA approved for use, but not on broken skin.
Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
Polyoxyethylene (40) stearate has also been used in a study to investigate its effects on multidrug resistance (MDR).
Polyoxyethylene (40) stearate belongs to the class of organic compounds known as fatty acid esters.
These are carboxylic ester derivatives of a fatty acid.
Polyoxyethylene (40) stearate is considered to be a practically insoluble (in water) and relatively neutral molecule.
Polyoxyethylene (40) stearate has been primarily detected in urine.
Polyoxyethylene (40) stearate is primarily located in the membrane (predicted from logP) and cytoplasm.
Polyoxyethylene (40) stearates were trimethylsilylated and injected onto a WCOT 50 m X 0.25 mm CP-SIL 5 CB fused silica column.
Characteristic profiles can be obtained from Polyoxyethylene (40) stearate deriv carrying different functional groups.
Polyoxyethylene (40) stearate is used in cosmetics and beauty products primarily as a surfactant and emulsifier.
Polyoxyethylene (40) stearate occurs naturally as a white, waxy or flaky substance, according to The Food and Agriculture Organization of the United Nations.
Polyoxyethylene (40) stearate, as part of the PEG Stearate group, are formed from a naturally fatty acid known as Stearic Acid.
Polyoxyethylene (40) stearates are used in cosmetics and skin care formulas because they can "clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
Polyoxyethylene (40) stearate is also used as an excipient in many pharmaceutical products.
Polyoxyethylene (40) stearate is the basis of a number of laxatives.
Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Polyoxyethylene (40) stearate has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm, and similar cases.
Polyoxyethylene (40) stearate replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, Polyoxyethylene (40) stearate is used when working with green wood as a stabilizer, and to prevent shrinkage.
Polyoxyethylene (40) stearate has been used to preserve the painted colors on unearthed at a UNESCO World Heritage site in China.
The paint would subsequently flake off in about four minutes.
Polyoxyethylene (40) stearate is preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
Polyoxyethylene (40) stearate is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
Polyoxyethylene (40) stearate derivatives, such as narrow range ethoxylates, are used as surfactants.
Polyoxyethylene (40) stearate has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
Polyoxyethylene (40) stearate has also been used as a propellent.
Polyoxyethylene (40) stearate is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Polyoxyethylene (40) stearate is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
Polyoxyethylene (40) stearate is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.
Polyoxyethylene (40) stearate precipitation is used to concentrate viruses.
Polyoxyethylene (40) stearate is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be Polyoxyethylene (40) stearate-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.
The size of the Polyoxyethylene (40) stearate polymer has been shown to be important, with larger polymers achieving the best immune protection.
Polyoxyethylene (40) stearate is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin).
Polyoxyethylene (40) stearate is used in a number of toothpastes as a dispersant.
Polyoxyethylene (40) stearate binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Polyoxyethylene (40) stearate is also under investigation for use in body armor, and in tattoos to monitor diabetes.
Polyoxyethylene (40) stearate has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
Polyoxyethylene (40) stearate is also used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving Polyoxyethylene (40) stearate, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
Polyoxyethylene (40) stearate is injected into industrial processes to reduce foaming in separation equipment.
Polyoxyethylene (40) stearate is used to extend the size and durability of very large soap bubbles.
Polyoxyethylene (40) stearate is the main ingredient in many personal lubricants.
When Polyoxyethylene (40) stearate is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), Polyoxyethylene (40) stearate can sometimes be antigenic, stimulating an anti-Polyoxyethylene (40) stearate antibody response in some patients.
This effect has only been shown for a few of the many available Polyoxyethylene (40) stearateylated therapeutics, but Polyoxyethylene (40) stearate has significant effects on clinical outcomes of affected patients.
Other than these few instances where patients have anti-Polyoxyethylene (40) stearate immune responses, Polyoxyethylene (40) stearate is generally considered to be a safe component of drug formulations.
Polyoxyethylene (40) stearate is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane.
Polyoxyethylene (40) stearate is coupled to hydrophobic molecules to produce non-ionic surfactants.
Polyoxyethylene (40) stearates potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.
Polyoxyethylene (40) stearates are nephrotoxic if applied to damaged skin.
Polyoxyethylene (40) stearate is very sensitive to sonolytic degradation and Polyoxyethylene (40) stearate degradation products can be toxic to mammalian cells.
Polyoxyethylene (40) stearate is, thus, imperative to assess potential Polyoxyethylene (40) stearate degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.
Polyoxyethylene 40 stearate is soluble in ethylacetate, methanol, ethanol, and water.
Polyoxyethylene (40) stearate is used in a study to investigate its effects on multidrug resistance (MDR) and to assess the phase behaviours of micro-emulsion to produce nanostructured drug-loaded lipid carriers.
Polyoxyethylene (40) stearate enhances antitumor activity and modulates multidrug resistance of vinblastine sulphate, which is one of the major hurdles limiting the efficacy of cancer chemotherapy.
Polyoxyethylene (40) stearate is a multifunctional neutral surfactant used in polishes and paper, food products, textile chemicals, household products, pharmaceutical formulations, and cosmetic formulations.
Polyoxyethylene (40) stearate is waxy or flaky white to creamy coloured substance used as surfactant and emulsifier agent in beauty products and cosmetics.
Polyoxyethylene (40) stearate is also known as PEG-40 stearate and polyoxyl 40 stearate.
Polyoxyethylene (40) stearate is used on skin burn or skin irritation with anti-microbial cream or ointment.
Polyoxyethylene (40) stearate market is growing at a significant growth over the forecast period, owing to rapid growth of emulsifiers in personal care industry.
Polyoxyethylene (40) stearate is a non-ionic emulsifying agent.
Polyoxyethylene (40) stearate is a synthetic polymer composed of PEG (polyethylene glycol) and stearic acid, a naturally occurring fatty acid.
Due to the presence of Polyoxyethylene (40) stearate, this ingredient may contain potentially toxic manufacturing impurities such as 1,4-dioxane.
APPLICATION:
-Pharmaceutical
-Personal Care
-Cosmetics
-Textile Chemicals
-Polishes and Paper
-Household Products
-Food
FUNCTION:
-Lubricating Agent
-Emulsifying Agent
-Additive
CLASSIFICATION:
-Nonionic surfactant: A surfactant with an uncharged hydrophilic headgroup.
-food emulsifier: A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
-emulsifier: The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability.
APPLICATION:
-Food emulsifier:A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
PROPERTIES:
-description: non-ionic
-Quality Level: 100
-form: powder
-application(s): detection
-InChI: 1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
-InChI key: RFVNOJDQRGSOEL-UHFFFAOYSA-N
STORAGE:
Keep in sealed, unopened, original containers
SYNONYM:
E431
macrogol 40 stearate
macrogol stearate 2000
PEG stearate
polyethylene glycol monostearate
polyethylene glycol stearate
polyoxyethylene (40) monostearate
polyoxyethylene (40) stearate
polyoxyethylene monostearate
polyoxyethylene stearate
polyoxyl 40 stearate
polyoxyl 8 stearate
stearic acid, monoester with polyethylene glycol
