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DESCRIPTION:
Polysorbates are synthetic additives made from sorbitol (E420).
They are effective emulsifiers used in dairy products, coconut milk, soups, sauces and in food supplements.
Various studies, carried out on mice, suggest that the consumption of these additives could increase the permeability of the intestinal barrier and thus promote chronic inflammatory bowel diseases, increased adiposity (metabolic syndrome) and the development of diabetes.
CAS: 9005-71-4
SYNONYMS of POLYOXYETHYLENE SORBITAN TRISTEARATE (POLYSORBATE 65)
Polysorbate 65,Tween 65,14BGY2Y3MJ,Peg-20 sorbitan tristearate,Polyoxyethylene (20) sorbitan tristearate,DTXSID30891988,E-436,Emsorb 6907,Glycosperse TS 20,INS NO.436,INS-436,JEESORB STS-20,LIPOSORB TS-20,NIKKOL TS-30,POLYSORBATE 65 (II),Peg sorbitan tristearate,SORBAX PTS-20,Sorbimacrogol tristearate 300,Sorbitan, tristearate, polyoxyethylene derivs.,UNII-14BGY2Y3MJ
These additives could also disrupt the balance of the intestinal flora, promoting autoimmune reactions.
Finally, the chronic intestinal inflammation caused by these emulsifiers could promote the development of colon cancer.
PROPERTIES OF POLYOXYETHYLENE SORBITAN TRISTEARATE (POLYSORBATE 65):
Main function
Texturing agent
Family
Polysorbates
Examples of employment products
Flavored dairy products, coconut milk, ice creams, food supplements, chewing gum, pastries, broths and soups, sauces in particular
ADI (value in mg/kg bw/day)
25 (grouped E432 to E436)
Authorized in organic
No
Possible allergy
No
English name: Polyoxyethylene (20) Sorbitan Tristearate or Polysorbate 65
Code name: Polyoxyethylene sorbitan tristearate (Tween 65)
Appearance:yellow clear oily liquid or paste
HLB Value: 10.5
CAS number: 9005-71-4
Chemical formula:C100H194O26
SAFETY INFORMATION ABOUT POLYOXYETHYLENE SORBITAN TRISTEARATE (POLYSORBATE 65)
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
