POLYOXYL 40 CASTOR OIL

Polyoxyl 40 castor oil is a polyethylene glycol derivative of hydrogenated castor oil where the average PEG chain length is 40. 
Polyoxyl 40 castor oil is a nonionic surfactant used as an emulsifying and solubilising agent in pharmaceutical preparations and cosmetics.
Polyoxyl 40 castor oil is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide.

CAS:    61791-12-6
EINECS:    500-151-7

Synonyms
polyoxyethylene castor oil;POLYOXYETHYLENE(10) CASTOR OIL;POLYETHYLENEGLYCOL CASTOR OIL;Castoroil,ethyleneglycolpolymer;Castoroil,ethyleneoxidereactionproduct;Castoroil,polyethoxylated;castoroilpolyoxyethyleneether;polyethoxylatedcastoroil
 
Polyoxyl 40 castor oil is a pale yellow oily liquid that is clear at temperatures above 26°C. 
Polyoxyl 40 castor oil has a faint but characteristic odour.
Polyoxyl 40 castor oil is an emollient and emulsifying agent created from a mixture of synthetic polyethylene glycol (PEG) + natural castor oil. 
Polyoxyl 40 castor oil also helps other ingredients solubilize in a formula which improves both aesthetics and performance. 
Essentially, Polyoxyl 40 castor oil meshes water and oil substances, as well as allows other ingredients to dissolve cohesively for a pleasing result.

Polyoxyl 40 castor oil Chemical Properties
Boiling point: 232.6℃[at 101 325 Pa]
Density: 1.05 g/mL at 20 °C
Vapor pressure: 0Pa at 25℃
Fp: 257℃
Storage temp.: REFRIGERATOR (+4C)
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Form: Viscous Liquid
Pka: 0[at 20 ℃]
Color: Clear yellow
Odor: at 100.00?%. bland
PH: 5.0-7.0 (1g/10 mL in H2O)
Water Solubility: 24.11mg/L at 25℃
Stability: Stable. Incompatible with storng oxidizing agents.
LogP: 4.297 at 25℃
CAS DataBase Reference: 61791-12-6
EPA Substance Registry System: Ethoxylated castor oil (61791-12-6)

Uses    
Polyoxyl 40 castor oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth.
Polyoxyl 40 castor oil has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. 
Polyoxyl 40 castor oil has been used as a vehicle for drug/stimulant delivery in cells.

Biochem/physiol Actions    
Polyoxyl 40 castor oil is used in lipid-based formulations for drugs and solubilization of cosmetics. 
Polyoxyl 40 castor oil is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. 
Due to its emulsification functionality, Polyoxyl 40 castor oil finds application in biological membrane- based drug transport studies.