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POLYVINYLPOLYPYRROLIDONE

CAS NUMBER: 144470-64-4

InChI: 1S/C6H13NOP2/c8-5-2-1-3-7(5)6(10)4-9/h6H,1-4,9-10H2 

MOLECULAR FORMULA: C6H13NOP2

MOLECULAR WEIGHT: 177.12

IUPAC NAME: 1-[1,2-bis(phosphanyl)ethyl]pyrrolidin-2-one


Polyvinylpolypyrrolidone (PVPP) is a polyphenol adsorbant. 
The Polyvinylpolypyrrolidone treatment can complement a protein adsorption treatment 

But Polyvinylpolypyrrolidone can also be used as the only treatment. 
Polyvinylpolypyrrolidone can be added to the maturation tank or dosed online to beer going to filtration.

Polyvinylpolypyrrolidone (polyvinyl polypyrrolidone, PVPP, crospovidone, crospolividone or E1202) is a highly cross-linked modification of polyvinylpyrrolidone (PVP).
The cross-linked form of PVP is used as a disintegrant (see also excipients) in pharmaceutical tablets.

Polyvinylpolypyrrolidone is a highly cross-linked version of PVP, making it insoluble in water, though it still absorbs water and swells very rapidly generating a swelling force. 
This property makes it useful as a disintegrant in tablets.

Polyvinylpolypyrrolidone can be used as a drug, taken as a tablet or suspension to absorb compounds (so-called endotoxins) that cause diarrhea. (Cf. bone char, charcoal.)
Polyvinylpolypyrrolidone is also used as a fining to extract impurities (via agglomeration followed by filtration). 

Polyvinylpolypyrrolidone is used in winemaking. 
Using the same principle Polyvinylpolypyrrolidone is used to remove polyphenols in beer production and thus clear beers with stable foam are produced.

Polyvidone is used as:
- a diluent in colour additive mixtures for marking food

-in coatings on fresh citrus fruits

-as a clarifying agent for beer, wine and vinegar

-as a tableting adjuvant

A cross-linked form of PVP is also used as a disintegrant (see also excipients) in pharmaceutical tablets. 
Polyvinylpolypyrrolidone is also known as cross-linked polyvinyl pyrrolidone, Polyvinyl Polypyrrolidone (PVPP), crospovidone, crospolividone. 

Basically, Polyvinylpolypyrrolidone is a highly cross-linked version of PVP, which makes it insoluble in water but it still absorbs water and swells very rapidly and generate a swelling force. 
That is why Polyvinylpolypyrrolidone can be used a disintegrant in tablets. 

Polyvinylpolypyrrolidone is also used to bind impurities to remove them from solutions.
Polyvinylpolypyrrolidone is also used as a fining to extract impurities (via agglomeration followed by filtration). 

Using the same principle it is used to remove polyphenols in beer production and thus clear beers with stable foam are produced. 
Polyvinylpolypyrrolidone can be used as well as a drug taken as a tablet or suspension and it absorbs compounds (so called Endotoxins) causing diarrhoea.

As a food additive, PVP is a stabilizer and has E number E1201. 
Polyvinylpolypyrrolidone is E1202. 
Polyvinylpolypyrrolidone is also used in the wine industry as a fining agent for white wine. 

Other references state that as polyvinyl pyrrolidone and its derivatives are fully from mineral synthetic origin. Therefore, its use in the production should not be a problem for vegans. 
PVP is soluble in water and other polar solvents. 

In water Polyvinylpolypyrrolidone has the useful property of Newtonian viscosity. 
When dry Polyvinylpolypyrrolidone is a light flaky powder, which readily absorbs up to 40% of its weight in atmospheric water. 

In solution, Polyvinylpolypyrrolidone has excellent wetting properties and readily forms films. 
This makes Polyvinylpolypyrrolidone good as a coating or an additive to coatings. 

PVP was first synthesized by Prof. Walter Reppe and a patent was filed in 1939 for one of the most interesting derivatives of acetylene chemistry. 
PVP was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. 

Polyvinylpolypyrrolidone (PVPP, crospovidone) is a highly cross-linked modification of PVP. 
Polyvinylpyrrolidone (PVP) is a water-soluble polymer made from the monomer N-vinylpyrrolidone:.

One such commercial product is called Polyclar. 
Polyvinylpolypyrrolidone forms bonds similar to peptidic bonds in protein (especially, like proline residues) and that is why it can precipitate tannins the same way as proteins do.
Polyvinylpolypyrrolidone has E number code E1202 and is used as a stabiliser.

Insoluble polyvinylpolypyrrolidone is a polymer poly[1-(2-oxo-1-pyrrolidinylethylene] reticulated to render it insoluble. 
Polyvinylpolypyrrolidone is made by polymerisation of N-vinyl-2-pyrrolidone in the presence of different catalysers (for example sodium hydroxide) or in the presence of N'Ndivinylimidazolidone.

Polyvinylpolypyrrolidone fixes the polyphenols in wines; this adsorption depends on the rate of polymerisation. 
Polyvinylpolypyrrolidone's application rate is limited.

Polyvinylpolypyrrolidone is Light powder, white and creamy white.
Polyvinylpolypyrrolidone is Insoluble in water and in organic solvents.

Polyvinylpolypyrrolidone is Insoluble in strong acid minerals and in alkaly.
Polyvinylpolypyrrolidone is used as an excipient to prepare samples for subsequent analysis steps. 

Polyvinylpolypyrrolidone has a wide range of applications, especially in the beverage industry. 
Polyvinylpolypyrrolidone is used to pre-treat samples such as juices with strong colors

Polyvinylpolypyrrolidone is short for polyvinylpolypyrrolidone which is a polymerized and water/beer insoluble version of the soluble compound PVP (polyvinylpyrrolidone), a nylon-type polymer that has an even higher affinity for chemical bonding with polyphenols than the proteins present in beer have. 
This gives Polyvinylpolypyrrolidone excellent properties as a chemical stabilizer for beer. 
If finely granulated, high surface area PVPP is dispersed in beer, a very high proportion of the dissolved polyphenols in the beer will bind to the PVPP particles, subsequently to be filtered out. 
Brewers wish to remove these polyphenols because they will otherwise with time react with beer proteins, forming insoluble complexes that will make the beer hazy. 
This type of stabilizer is referred to as an adsorbent.

Polyvinylpolypyrrolidone's Functions:
*Binder / Stabilizer: Polyvinylpolypyrrolidone Retains the physical characteristics of food/cosmetics and ensure the mixture remains in an even state.

*Emulsifier: Polyvinylpolypyrrolidone Allows water and oils to remain mixed together to form an emulsion.

*Gelling Agent / Thickener: Polyvinylpolypyrrolidone Increases the viscosity by thickening the liquid to give it more texture

Polyvinylpolypyrrolidone, also known as polyvinyl polypyrrolidone, PVPP, crospovidone or crospolividone, is a highly cross-linked modification of polyvinylpyrrolidone (PVP).
Polyvinylpolypyrrolidone is used as a disintegrant in pharmaceutical tablets. 

Polyvinylpolypyrrolidone is also used as a fining to extract impurities (via agglomeration followed by filtration). 
Polyvinylpolypyrrolidone is used in winemaking. Using the same principle it is used to remove polyphenols in beer production and thus clear beers with stable foam are produced.

Polyvinylpolypyrrolidone can be used as a stabilizer and has E number 1202. 
Polyvinylpolypyrrolidone is approved to use as food additive in EU.

Alternative Classes:    
-Pyrrolidine-2-ones 
-Tertiary carboxylic acid amides 
-Lactams 
-Azacyclic compounds 
-Organopnictogen compounds 
-Compounds containing a bond between carbon a pnictogen atom. Pnictogens are p-block element atoms that are in the group 15 of the periodic table.
-Organophosphorus compounds 
-Organonitrogen compounds 
-Organic oxides 
-Hydrocarbon derivatives 
-Carbonyl compounds 

In many cases, it means using plastic instead of leather, processed industrial soy products instead of milk, and in the case of wine, Polyvinylpolypyrrolidone instead of milk or egg or fish proteins to stabilse, clarify, and reduce phenolic flavours.
Polyvinylpolypyrrolidone or PVPP is essentially a plastic.

Polyvinylpolypyrrolidone powder (Polyvinylpolypyrrolidone), also known as polyclar. 
This material is used primarily as a fining agent with white wines and provides rapid clarification and reduction in bitterness and brown colors in white wines. 

Polyvinylpolypyrrolidone reduces a lot of color in reds.
Polyvinylpolypyrrolidone is a highly cross-linked variant of PVP making it water insoluble, but it still can absorb a lot of water and swells by doing so. 

Polyvinylpolypyrrolidone is used in pharmaceuticals and wine & beer clarification.
Polyvinylpolypyrrolidone is primarily used to clarify wines & reduce bitterness as well as reducing brown coloring in white wines, will also improve the hue in reds and rosè.

Polyvinylpolypyrrolidone can also be used to remove the  pink colour and pinking precursor compounds in white wines.  
Polyvinylpolypyrrolidone is a gentle fining agent which preserves wine aroma, unlike some other fining agents on  the market.

Substituents:    
-Pyrrolidone
-2-pyrrolidone
-N-alkylpyrrolidine
-Tertiary carboxylic acid amide
-Carboxamide group
-Lactam
-Carboxylic acid derivative
-Azacycle
-Organic oxide
-Organopnictogen compound
-Organic oxygen compound
-Organic nitrogen compound
-Organophosphorus compound
-Organooxygen compound
-Organonitrogen compound
-Carbonyl group
-Hydrocarbon derivative
-Aliphatic heteromonocyclic compound

Polyvinylpolypyrrolidone powder (Polyvinylpolypyrrolidone), also known as polyclar. 
Polyvinylpolypyrrolidone is used primarily as a fining agent with white wines and provides rapid clarification and reduction in bitterness and brown colors in white wines

What is Polyvinylpolypyrrolidone made from?
Polyvinylpolypyrrolidone is a synthetic, high-molecular-weight clarifying agent made up of cross-linked monomer of polyvinylpyrrolidone. 
Polyvinylpolypyrrolidone has long been used in the beverage industry as a polyphenol adsorben

What is Polyvinylpolypyrrolidone (PVPP)?
Definition: What does Polyvinylpolypyrrolidone (PVPP) mean? Polyvinylpolypyrrolidone, or PVPP, is a polymer (a substance of synthetic organic materials utilized as a resin or plastic) sometimes chosen as a fining agent in wine.

Polyvinylpolypyrrolidone Belongs to the class of organic compounds known as n-alkylpyrrolidines. 
Polyvinylpolypyrrolidone is compound containing a pyrrolidine moiety that is substituted at the N1-position with an alkyl group. 
Pyrrolidine is a five-membered saturated aliphatic heterocycle with one nitrogen atom and four carbon atoms.


PHYSICAL PROPERTIES:

-Molecular Weight: 177.12    

-XLogP3-AA: -0.7    

-Exact Mass: 177.04723803    

-Monoisotopic Mass: 177.04723803    

-Topological Polar Surface Area: 20.3 Ų

-Ignition temperature: 440 °C

-Melting Point: 110 - 180 °C (glass temperature)

-Water Solubility: 42.97 mg/L @ 25 °C 

-Bulk density: 330 kg/m3

-logP: -1.4    

-logS: 0    

-pKa (Strongest Basic): -1.1    

-Density: 1.2 g/cm3


Polyvinylpolypyrrolidone is used as a disintegrant in pharmaceutical tablets. 
Polyvinylpolypyrrolidone can be used as a drug, taken as a tablet or suspension to absorb compounds (so-called endotoxins) that cause diarrhea. (Cf. bone char, charcoal.)

Polyvinylpolypyrrolidone is also used as a fining to extract impurities (via agglomeration followed by filtration). 
Polyvinylpolypyrrolidone is used in winemaking. 

Polyvinylpolypyrrolidone is also used to bind impurities to remove them from solutions.
Polyvinylpolypyrrolidone is also used as a fining to extract impurities (via agglomeration followed by filtration). 


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 0    

-Hydrogen Bond Acceptor Count: 1    

-Rotatable Bond Count: 2    

-Heavy Atom Count: 10    

-Formal Charge: 0    

-Complexity: 140    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 1    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 1    

-Compound Is Canonicalized: Yes

-Refractivity: 43.21 m³·mol⁻¹    

-Polarizability: 16.67 ų    

-Number of Rings: 1    

-Bioavailability: Yes


Polyvinylpolypyrrolidone is Light powder, white and creamy white.
Polyvinylpolypyrrolidone is Insoluble in water and in organic solvents.
Polyvinylpolypyrrolidone is Insoluble in strong acid minerals and in alkaly.

Polyvinylpolypyrrolidone is used as an excipient to prepare samples for subsequent analysis steps. 
Polyvinylpolypyrrolidone has a wide range of applications, especially in the beverage industry. 

Polyvinylpolypyrrolidone is used to pre-treat samples such as juices with strong colors
Polyvinylpolypyrrolidone is also used as a fining to extract impurities (via agglomeration followed by filtration). 

Polyvinylpolypyrrolidone is used in winemaking. Using the same principle it is used to remove polyphenols in beer production and thus clear beers with stable foam are produced.
Polyvinylpolypyrrolidone can be used as a stabilizer and has E number 1202. 
Polyvinylpolypyrrolidone is approved to use as food additive in EU.


SYNONYMS:

poly(1-ethenylpyrrolidin-2-one)
Crospovidone (nomenclature of pharmacope)
Reticulated polyvidone
Reticulated homopolymer of 1-ethenyl-2-pyrrolidone
Reticulated insoluble polymer of N-vinyl-2-pyrrolidone
P.V.P. insoluble
Polyvinylpolypyrrolidone (PVPP)
Alphadine     
Alphadines     
Enterode     
Lacophtal     
Liquifilm lagrimas     
Nutrivisc     
PVP 40     
PVP Iodine     
PVP-Iodine     
PVP-Iodines     
Pharmadine     
Pharmadines     
Polyvinylpyrrolidone     
Povidone-iodine     
Povidone-iodines     
Protagens     
Unspecified povidone     
Wet-comod     
Disadine     
Duratears free     
Hypotear     
Isodine     
Lagrifilm     
PVP-I     
Periston     
Polyvidon     
Povidone iodine     
Povidone, unspecified     
Protagen     
Protagent     
Providines     
Betaisodona     
Disadines     
Dulcilarme     
Enterodez     
Hypotears     
Isodines     
Lacri-stulln     
Polvidone     
Povidone     
Providine     
Vidisic PVP ophtiole     
Arufil     
Betadine     
Betadines     
Bolinan     
Bolinan 40     
Crospovidone     
Dulcilarmes     
Enterodes     
Kollidon     
Oculotect     
Plasdone     
Polyplasdone XL     
Polyvidons     
Polyvinylpyrrolidone iodine     
Polyvinylpyrrolidone iodines     
Unifluid     
Vidirakt S mit PVP     
'Kollidon 25'     
'plasdone'     
1-Ethenyl-2-pyrrolidinone     
1-Ethenyl-2-pyrrolidinone (9ci)     
1-Ethenyl-2-pyrrolidinone homopolymer     
1-Ethenyl-2-pyrrolidinone homopolymer, 9ci     
1-Ethenyl-2-pyrrolidinone polymers     
1-Ethenyl-2-pyrrolidinone, homopolymer     
1-Vinyl-2-pyrrolidinone     
1-Vinyl-2-pyrrolidinone cross-linked insoluble polymer     
1-Vinyl-2-pyrrolidinone homopolymer     
1-Vinyl-2-pyrrolidinone polymer     
1-Vinyl-2-pyrrolidinone, monomer     
1-Vinyl-2-pyrrolidinone, polymer     
1-Vinyl-2-pyrrolidone     
1-Vinyl-2-pyrrolidone polymer     
1-Vinylpyrrolidin-2-one     
1-Vinylpyrrolidinone     
1-Vinylpyrrolidone     
2-Pyrrolidinone, 1-ethenyl, homopolymer     
2-Pyrrolidinone, 1-ethenyl-, homopolymer     
2-Pyrrolidinone, 1-vinyl-, polymers     
Agent at 717     
Agent at-717     
Agrimer     
Albigen a     
Aldacol Q     
Antaron P 804     
Ganex P 804     
Ganex P-804     
Hemodesis     
Hemodez     
K 115 (Polyamide)     
K 25 (Polymer)     
K 25     
K 30 (Polymer)     
K 30     
K 60 (Polymer)     
K 60     
K115 (Polyamide)     
K25 (Polymer)     
K30 (Polymer)     
K60 (Polymer)     
Kollidin CLM     
Kollidon 17     
Kollidon 25     
Kollidon 30     
Kollidon CL     
Luviskol     
Luviskol K 30     
Luviskol K 90     
Luviskol K-30     
Luviskol K30     
Luviskol K90     
N-Vinyl pyrrolidone     
N-Vinyl-2-pyrrolidinone     
N-Vinyl-2-pyrrolidone     
N-Vinyl-2-pyrrolidone polymer     
N-Vinylbutyrolactam polymer     
N-Vinylpyrrolidinone     
N-Vinylpyrrolidinone polymer     
N-Vinylpyrrolidone     
N-Vinylpyrrolidone polymer     
N-Vinylpyrrolidone-2     
Neocompensan     
Peragal ST     
Peregal ST     
Periston-N     
Peviston     
Plasdone 4     
Plasdone K 29-32     
Plasdone K-26/28     
Plasdone no. 4     
Plasdone XL     
Plasmosan     
Polividone     
Poly(1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl)     
Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)     
Poly(1-ethenyl-2-pyrrolidinone)     
Poly(1-vinyl-2-pyrrolidinone)          
Poly(1-vinyl-2-pyrrolidone)     
Poly(1-vinylpyrrolidinone)     
Poly(N-vinyl-2-pyrrolidinone)     
Poly(N-vinyl-2-pyrrolidone)     
Poly(N-vinylbutyrolactam)     
Poly(N-vinylpyrrolidinone)     
Poly(N-vinylpyrrolidone)     
Poly(vinylpolypyrrolidone)     
Poly(vinylpyrrolidinone)     
Poly(vinylpyrrolidone)     
Poly-N-vinyl pyrrolidone     
Poly-N-vinylpyrrolidone     
Polyclar a. t     
Polyclar a. t.     
Polyclar at     
Polyclar H     
Polyclar L     
Polyclar-at     
Polygyl     
Polyplasdone     
Polyvidonum     
Polyvinyl pyrrolidone     
Polyvinylpolypyrrolidone     
Polyvinylpyrrolidone polymers     
Polyvinylpyrrolidone, cross-linked     
Povidone(usan)     
Povidone, ban, usan     
PVP 1     
PVP 2     
PVP 3     
PVP 4     
PVP 5     
PVP 6     
PVP 7     
PVP K 3     
PVP-K 15     
PVP-K 3     
PVP-K 30     
PVP-K 60     
PVP-K 90     
PVP10_SIAL     
PVP40_SIAL     
PVPP     
Refresh     
Sauflon     
Soothe     
Subtosan     
Tears plus     
Tolpovidone I 131     
Tolpovidone I-131     
Toxobin    
V-Pyrol    
Vinisil    
Vinyl-2-pyrrolidone    
Vinylbutyrolactam    
Vinylpyrrolidinone    
Vinylpyrrolidinone polymer    
Vinylpyrrolidone    
Vinylpyrrolidone polymer    
Betaisodonas
 

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