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Polyvinylpyrolidone K 30 may be used as an emulsion stabiliser in creams and lotions, and as a dispersant for hair colourants.
Polyvinylpyrolidone K 30 is used as stationary liquid for gas chromatography.
Polyvinylpyrolidone K 30 is used as a colloidal stabilizer and clarifier, can be used for the clarification of beer, according to the production needs of the appropriate amount of use.
CAS Number: 9003-39-8
MDL number: MFCD00149016
Linear Formula: (C6H9NO)n
SYNONYMS:
PVP, Povidone, Polyvidone, Kollidon, Poly[1-(2-oxo-1-pyrrolidinyl)ethylene], 1-Ethenyl-2-pyrrolidinone homopolymer, 1-Vinyl-2-pyrrolidinone polymer, Poly-N-vinylpyrrolidone, PVP K30 1-ethenylpyrrolidin-2-one Povidone Polyvidone E1201 Poly[1-(2-oxo-1-pyrrolidinyl)ethylen] (C6H9NO)n poly(vinylpyrrolidone) Povidone K29/32 1-vinylpyrrolidin-2-one homopolymer PVP K-30 Plasdone K29-32 Plasdone K29/32 Polyvinylpyrrolidone K 30 Polyvinylpyrrolidone K-29/32, Polyvinylpyrrolidone, Polyvinyl pyrrolidone, PVP, Polyvidone, 1-Ethenylpyrrolidin-2-one, Copovidone, PVPP, 2-Pyrrolidinone,1-ethenyl-,homopolymer, 2-Pyrrolidinone,1-vinyl-,polymers, Albigen A, Kollidon, Luviskol K 30, Plasdone, Plasdone 4, Polyvidone, Poly(1-vinyl-2-pyrrolidinone), Povidone, PVP, Subtosan, Vinisil, Poly(N-vinylpyrrolidinone), Poly(vinylpyrrolidone), Poly(vinylpyrrolidinone), Poly(N-vinylpyrrolidone), Peviston, Polyclar AT, Vinylpyrrolidinone polymer, Peregal ST, Luviskol K 90, Periston, Agent AT 717, Poly(N-vinylbutyrolactam), Poly(1-vinyl-2-pyrrolidone), Poly(N-vinyl-2-pyrrolidinone), N-Vinylpyrrolidinone polymer, N-Vinylpyrrolidone polymer, PVP-K 90, Vinylpyrrolidone polymer, K 60, K 115 (vinyl polymer), N-Vinylbutyrolactam polymer, Periston N, Poly(N-vinyl-2-pyrrolidone), PVP-K 3, Antaron P 804, Poly(N-vinyl-γ-butyrolactam), PVP 40, 143RP, Bolinan, Plasmosan, Protagent, 1-Vinyl-2-pyrrolidone polymer, N-Vinyl-2-pyrrolidone polymer, Kollidon 17, Neocompensan, Hemodez, K 115, MPK 90, AT 717, Kollidon 30, Polyclar H, Polyclar L, PVP 50, Plasdone K 29-32, K 15 (polymer), Plasdone XL, PVP-K 30, PVP-K 60, K 25, Hemodesis, Ganex P 804, K 60 (polymer), Poly(1-vinylpyrrolidinone), Polyplasdone XL, Kollidon 25, PVPP, Aldacol Q, Kollidon 90, Polyvidon, Plasdone C, Povidone K 29-32, PVP-K 25, K 15, Plasdone C 15, Kollidon K 25, SD 13 (polymer), SD 13, PVP 1230, Kollidon K 30, Kollidon CE 50/50, B 7509, K 90, Kollidon 12PF, PVP-K 15, Luviskol K 17, Luviskol K 25, PVP-K 40, NPK 15, NPK 90, Antitox Vana, NP-K 30, Kollidon 17PF, Povidone K 30, Plasdone K 15, 9015-62-7, 9080-59-5, 29386-94-5, 41724-41-8, 53026-73-6, 53026-74-7, 53200-27-4, 61932-72-7, 65931-56-8, 111214-46-1, 116404-61-6, 121414-75-3, 132778-04-2, 132778-05-3, 132834-20-9, 153631-61-9, 170473-90-2, 496908-06-6, 730985-60-1, 862983-74-2, 878051-55-9, 956148-96-2, 1173909-53-9, 1229193-79-6, 1234714-82-9, 1303541-78-7, 1310675-91-2, 1337987-71-9, 1394151-52-0, 1431958-26-7, 1694674-42-4, 1918127-90-8, 2062651-26-5, 2083718-66-3, 2083718-67-4, 2088158-90-9, 2100274-29-9, 2169285-59-8, Povidone K30, PVP-K 30, Povidone K29/32, 1-vinylpyrrolidin-2-one homopolymer, PVP K-30, PVP K30, Plasdone K29-32, Plasdone K29/32, Polyvinylpyrrolidone K 30, Polyvinylpyrrolidone K-29/32, Polyvinylpyrrolidone K30, Povidone K29-32, U725QWY32X, 390RMW2PEQ, KOLLIDON 30 LP, PLASDONE C-30, PLASDONE C30, POVIDONE IMPURITY A (EP IMPURITY), POVIDONE K29/32 (II), POVIDONE K30 (II), PVP, K-30, PVP-K, PVP-K30, PVP-K17, PVP-K25, PVP-K90, Povidone, PVP K 30, Crospovidone, Polyinylpyrrolidone, Polyvinylpyrrolidine, Polyvinylpyrrolidone, Polyvinglpyrrolidone, Polyvinyl pyrrolidone, poly vinyl pyrrolidone, Plasdone K29-32, Plasdone K29/32, Polyvinylpyrrolidone K 30, Polyvinylpyrrolidone K30, Povidone K29-32, Povidone K29/32, PVP K-30, PVP K30, PVP-K 30, Poly[1-(2-oxo-1-pyrrolidinyl)ethylene], Polyvinylpyrrolidone, Povidone, PVP, Polyvinylpyrrolidone, 2-Pyrrolidinone, 1-ethenyl-, homopolymer, 1-Vinyl-2-pyrrolidinon-Polymer
Polyvinylpyrolidone K 30 finds application in formulating hair care products like sprays, mousses, gels, styling lotions/creams, colourants and novelty stylers.
Polyvinylpyrolidone K 30 stabilises foam, emulsions, dispersions, and suspensions.
Polyvinylpyrolidone K 30 acts as a stabiliser and film former, providing a strong and stiff hold.
Polyvinylpyrolidone K 30 is a hygroscopic and amorphous polyvinylpyrrolidone polymer powder that shows excellent compatibility with acrylate thickeners.
Polyvinylpyrolidone K 30 is water-soluble, and is compatible with most inorganic salts and many resins.
Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer compound made from the monomer N-vinylpyrrolidone.
Polyvinylpyrolidone K 30 is available in a variety of molecular weights and corresponding viscosities (K) and can be selected according to the desired application properties.
Polyvinylpyrolidone K 30 is a synthetic polymer produced from the monomer vinylpyrrolidone.
Polyvinylpyrolidone K 30 is a polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.
Polyvinylpyrolidone K 30 is a white powder, with slightly odor.
Polyvinylpyrolidone K 30 is hygroscopic.
Polyvinylpyrolidone K 30 is soluble in water, ethanol, ether and other organic solvents.
Polyvinylpyrolidone K 30 has for a variety of substances have a strong ability to complex adsorption.
Polyvinylpyrrolidone, PVP is a non-ionic high molecular polymer.
PVP is classified according to its average molecular weight.
It is customarily used to indicate the K value.
Different K values represent different PVP average molecular weight ranges.
The K value is actually a characteristic value related to the relative viscosity of the PVP aqueous solution, and the viscosity is a physical value related to the molecular weight of the high molecular polymer.
Therefore, the K value can be used to characterize the average molecular weight of PVP.
Generally, the K value is more Large, the greater the viscosity.
Polyvinylpyrolidone K 30 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution.
Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications.
Polyvinylpyrolidone K 30 can be plasticized with water and most common organic plasticizers.
Polyvinylpyrolidone K 30 is considered to be physiologically inert:
Polyvinylpyrolidone K 30, also known as Povidone K-30, is a synthetic, water-soluble polymer derived from the monomer N-vinylpyrrolidone.
The 'K' value indicates the average molecular weight of the polymer; for PVP K-30, this corresponds to a molecular weight of approximately 40,000 g/mol.
Polyvinylpyrolidone K 30 is a powder or aqueous solution, soluble in water, alcohol, amine and halogenated hydrocarbons, insoluble in acetone, ether, etc.
Polyvinylpyrolidone K 30 has excellent solubility, biocompatibility, physiological inertness, film forming, membrane protection ability and the ability to combine a variety of organic and inorganic compounds.
Polyvinylpyrolidone K 30 is stable to acid, salt and heat, so it has a wide range of uses.
Polyvinylpyrolidone K 30 is a polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.
Polyvinylpyrolidone K 30 is the polymer of Vinyl Pyrrolidone.
Polyvinylpyrolidone K 30 is divided into soluble and insoluble.
Polyvinylpyrolidone K 30 is one of the 3 major main pharmaceutical excipients.
Polyvinylpyrolidone K 30 is a water-soluble synthetic polymer made from N-Vinyl Pyrrolidone monomer.
Viscosity and adhesion strength are determined by different molecular weights.
The higher the molecular weight, the stronger the viscosity and adhesion strength will be.
Polyvinylpyrolidone K 30 has an important place in the selection of wet granulation binders.
Polyvinylpyrolidone K 30 has important features to provide flexibility in wet granulation applications.
Polyvinylpyrolidone K 30 has spherical particle morphology.
Polyvinylpyrolidone K 30 is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.
By acting as a hair fixative Polyvinylpyrolidone K 30 is used in facial mask formulas By acting as a thickener / film former
Polyvinylpyrolidone K 30 is white powder or aqueous solution.
Polyvinylpyrolidone K 30 is easily dissolved in water, alcohol, amine and halohydrocarbon, but not dissolved in acetone and aether etc...
USES and APPLICATIONS of POLYVINYLPYROLIDONE K 30:
Polyvinylpyrolidone K 30 may be used as an emulsion stabiliser in creams and lotions, and as a dispersant for hair colourants.
Polyvinylpyrolidone K 30 is a polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.
Polyvinylpyrolidone K 30 is used as stationary liquid for gas chromatography
Polyvinylpyrolidone K 30 is used as a colloidal stabilizer and clarifier, can be used for the clarification of beer, according to the production needs of the appropriate amount of use.
Applications of Polyvinylpyrolidone K 30 take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.
High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.
Dispersancy, where components in a mixture are uniformly distributed through the use of Polyvinylpyrolidone K 30.
Hydrophilicity, where the substantial water solubility of Polyvinylpyrolidone K 30 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.
Adhesion, taking advantage of the higher molecular weight Polyvinylpyrolidone K 30 formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.
Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.
Polyvinylpyrolidone K 30 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry.
Polyvinylpyrolidone K 30 is used dishwashing liquids, dishwashing and laundry tablets, laundry detergents, and hard surface cleaners.
Food Industry: Polyvinylpyrolidone K 30 is employed as a stabilizer (E1201) and as a fining agent in wine and beer production, aiding in the clarification process.
Industrial Applications: Polyvinylpyrolidone K 30 is utilized as an adhesive in glue sticks and hot-melt adhesives, a dispersant in inks and coatings, and a binder in ceramics and batteries.
Polymerization Processes: Polyvinylpyrolidone K 30 acts as a stabilizer and dispersant in suspension polymerization processes.
Polyvinylpyrolidone K 30's versatility stems from its excellent solubility, adhesive properties, film-forming ability, and chemical stability, making it valuable across various industries.
Industrial applications of Polyvinylpyrolidone K 30 include use as an adhesive to improve strength and thickness; increase strength in paper production; use as a resin coating; improve dye coloration in synthetic fibers; also commonly used in inks, imaging, lithography, detergents and soaps , textiles, pottery, electricity, metallurgy, and as a polymerization additive.
Polyvinylpyrolidone K 30 is also widely used in the pharmaceutical industry due to its excellent adhesion, film formation, dispersion and thickening properties.
Polyvinylpyrolidone K 30 can also be used as a cryogenic preservative in medicine.
As a synthetic water-soluble polymer compound, Polyvinylpyrolidone K 30 has the general properties of water-soluble polymer compounds, such as colloidal protection, film-forming, cohesiveness, hygroscopicity, solubilization or coagulation, but it is the most distinctive, so it is favored People pay attention to its excellent solubility and physiological compatibility.
Among synthetic polymers, Polyvinylpyrolidone K 30 is soluble in both water and most organic solvents, with low toxicity and good physiological compatibility, especially in medicine, food, cosmetics, which are closely related to people's health.
In the field, with the price reduction of its raw material butyrolactone, Polyvinylpyrolidone K 30 will show a good prospect for its development.
Polyvinylpyrolidone K 30 is widely used in the field of medicine and is one of the three new pharmaceutical excipients advocated internationally.
The most widely used adhesives are tablets and granules.
Polyvinylpyrolidone K 30 can also be used as a flow aid for capsules, detoxification and lubricant for eye drugs, a co-solvent for injections, a dispersant for liquid preparations, and a stabilizer for enzymes and heat-sensitive drugs.
Polyvinylpyrolidone K 30 can also be synthesized with iodine povidone iodine (PVP-I) disinfectant.
In contact lenses, Polyvinylpyrolidone K 30 is used as a component of contact lenses to increase their hydrophilicity.
Polyvinylpyrolidone K 30 can also be used as a cryogenic preservative in medicine.
Polyvinylpyrolidone K 30 is used as a thickener and as a dispersing agent.
Polyvinylpyrolidone K 30is also used as a detoxicant, a complexing agent, a lubricant and a binder.
Polyvinylpyrolidone K 30 is used in the pharmaceutical industry.
Polyvinylpyrolidone K 30 has excellent adhesive, non-film-forming, dispersion and thickening properties and is widely used in the pharmaceutical industry.
Low molecular weight PVP-K is a commonly used solubilizing agent, crystallization inhibitor and suspension stabilizer for injection and ophthalmic formulations such as Polyvinylpyrolidone K 30.
Polyvinylpyrolidone K 30 is also used as a stabilizer for tablets, capsules and granules, a non-film forming agent for oral suspensions, as a solvent agent, a specialized enzyme stabilizer for pigments and to improve bioavailability such as Polyvinylpyrolidone K 30.
Industrial application of Polyvinylpyrolidone K 30: Suspensant, spreader and emulsifier, glass fiber, detergent, plastics and resins, ink, not p and coating, dies and Printing Textile, Film and adhesive, TV tube.
Polyvinylpyrolidone K 30 is used for research use only
Polyvinylpyrolidone K 30 is used in hair styling formulations.
Polyvinylpyrolidone K 30 has good solubility, biocompatibility and physiologically inert, non-film-forming character, colloid preservation ability and compounding ability of many organic or inorganic compounds.
Polyvinylpyrolidone K 30 is also widely used in acid, salt and heat, so it is continuous.
Applications of Polyvinylpyrolidone K 30: tablet binding and viscosifier
The most common sectors among the areas of use of Polyvinylpyrolidone K 30 are the pharmaceutical and cosmetic sectors.
The purpose of using Polyvinylpyrolidone K 30 in the cosmetic sector is to benefit from its ability to create a dispersion agent, hard and at the same time bright transparent film.
In the adhesive industry, in the manufacture of pressure-sensitive adhesives, as an emery binder, and as a viscosity-modifying agent in the production of ceramic-type products prepared at high temperatures.
Polyvinylpyrolidone K 30 is an important ingredient in hair sprays and lotions used to create wavy hair.
This synthetic polymer can be Polyvinylpyrolidone K 30.
Polyvinylpyrolidone K 30 is used in the manufacture of adhesives used to bond rubber to metal.
Polyvinylpyrolidone K 30 is used as a protective colloid and leveling agent in digital printing coating materials, ballpoint inks and emulsion polymers.
In the electronics industry, Polyvinylpyrolidone K 30 is used as a binder in cathode ray tubes, printed circuits and storage batteries.
Polyvinylpyrolidone K 30 is used to disperse titanium dioxide used in the textile industry.
Polyvinylpyrolidone K 30 is used in the manufacturing of coating components used on the surfaces of aluminum, copper, zinc and nickel metals in the coating industry.
Polyvinylpyrolidone K 30 is an excipient used in pharmaceutical products to disperse and suspend drugs.
Polyvinylpyrolidone K 30 is used in the production of pill form drugs used to relieve cold discomfort.
Polyvinylpyrolidone K 30 is used as a binding agent in the production of tablets used in dishwashers.
Polyvinylpyrolidone K 30 is used as a binding agent for tablets and capsules.
Polyvinylpyrolidone K 30 is used as a binder and complexing agent in agricultural applications such as plant protection, seed treatment and coating.
Polyvinylpyrolidone K 30 is used as a thickening agent in teeth whitening gels.
Polyvinylpyrolidone K 30 is used in the production of membranes such as water and dialysis.
Polyvinylpyrolidone K 30 is used as a stabilizing agent in the production of all inorganic solar cells.
Polyvinylpyrolidone K 30 a is used in personal care products such as shampoo and toothpaste, paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes.
Polyvinylpyrolidone K 30 helps clarify the wine by removing sediments in wine production.
Polyvinylpyrolidone K 30 is used as a complexing agent in the cosmetics industry in the manufacture of AHA-BHA containing skin care products and anti-aging products.
Polyvinylpyrolidone K 30 is used in beer production to clarify the beer.
Polyvinylpyrolidone K 30 is the raw material used to filter and retain sediment to clarify wine.
Polyvinylpyrolidone K 30 is used in the manufacture of hair sprays to provide a thin film layer on the hair with a shiny and wet lubrication effect.
Polyvinylpyrolidone K 30 is a good stabilizer for creatine in skin care and lotions in the cosmetics industry.
Polyvinylpyrolidone K 30 is used to create a complex in the production of cosmetic products containing AHA and BEHA to eliminate fine lines on the skin and revitalize aging skin.
Polyvinylpyrolidone K 30 is used as a base stock product in lipstick manufacturing.
In the recycling sector, Polyvinylpyrolidone K 30 is used as a binder to prevent glass fiber from dispersing during guillotine cutting.
Polyvinylpyrolidone K 30 is used to reduce some of its undesirable effects on the skin due to its detoxification effect.
During fabric washing, some dirt remains suspended.
Polyvinylpyrolidone K 30 is used to prevent the re-accumulation of suspended dirt.
Polyvinylpyrolidone K 30 is a synthetic polymer used in the manufacture of hair sprays and wavy hair styling lotions.
Polyvinylpyrolidone K 30 is used to increase the solubility of low solubility active ingredients in drug delivery systems.
Increasing the amount of Polyvinylpyrolidone K 30 can further increase the dissolution rate and effectiveness of the drug in the solid dispersant.
Polyvinylpyrolidone K 30 is used as a thickener for the anti-fading agents in Titanium and Titanium alloy facade coatings.
In addition, Guar Gum or Polyvinyl Alcohol is also used as a thickener in these applications.
Polyvinylpyrolidone K 30 is used as a dispersing agent in liquid preparations.
Polyvinylpyrolidone K 30 provides stabilization of drug derivatives such as heat-sensitive enzymes.
Polyvinylpyrolidone K 30 is used as a binding agent in the production of effervescent tablets used in dysphagia treatments.
-Polyvinylpyrolidone K 30 is used cosmetics industry in:
Polyvinylpyrolidone K 30 is widely used in hair care, skin care & oral care products in a wide range of applications.
The products are particularly suitable for formulations where viscosity change and film forming properties are required.
PVP-K products are particularly suitable for hair styling products.
Medium molecular weights such as Polyvinylpyrolidone K 30 are preferred where viscosity is critical in applications such as spray.
Higher molecular weight products such as PVP K90 are the best choice where high viscosity is required.
Polyvinylpyrolidone K 30 is commonly used in the following
-Polyvinylpyrolidone K 30 is used in cosmetics
* hair gels
* hair foams
* liquid hair setting preparations
* sprays pump
-Pharmaceutical Industry uses of Polyvinylpyrolidone K 30: Polyvinylpyrolidone K 30 serves as a binder in tablet formulations, enhancing the cohesion of tablet ingredients. Polyvinylpyrolidone K 30 also acts as a stabilizer for oral suspensions and as a solubilizing agent for active pharmaceutical ingredients.
-Cosmetics and Personal Care uses of Polyvinylpyrolidone K 30:
Polyvinylpyrolidone K 30 functions as a film-forming agent in hair styling products, providing flexibility and hold.
Additionally, Polyvinylpyrolidone K 30 is used as a thickener and stabilizer in creams, lotions, and toothpaste.
FEATURES AND BENEFITS OF POLYVINYLPYROLIDONE K 30:
*highly adhesive polymer- excellent tablet binding capacity at low concentration producing hard, non-friable tablets
*excellent solubility in water and non polar solvents- can be added as an aqueous or non-aqueous solution to wet granulation tablet processes.
*dissolves quickly; does not delay disintegration or dissolution
*forms lubricious hydrogels and coatings for medical devices
low solution viscosity- workable solution viscosity at high polymer levels makes it easy-to-use in granulation and other manufacturing equipment
*non-ionic- solution viscosity is not affected by changes in pH or the presence of electrolytes, ill not form complexes or interact with ionic drug actives
*interfacially active- acts as a drug solubilizer, inhibits crystallization of drug actives and inactive ingredients, stabilizes suspensions, dispersions and emulsions
HOW IS POLYVINYLPYROLIDONE K 30 PRODUCED?
The production of Polyvinylpyrolidone K 30 comes from the polymerization of Vinylpyrrolidone under a basic catalyst and the presence of N,N'-divinyl amide and cross-inking reaction.
During the production process of Polyvinylpyrolidone K 30 , reflux is achieved by using a certain concentration of Acetic Acid and Ethyl Alcohol until it is extracted .
In the presence of Ammonia and some Amines and also with Hydrogen Peroxide as catalyst purified 1-vinyl-2-pyrrolidone is obtained.
After further purification the final product is obtained.
WHAT ARE POLYVINYLPYROLIDONE K 30'S PHYSICAL AND CHEMICAL PROPERTIES?
In terms of physical appearance, Polyvinylpyrolidone K 30 is in the form of a free-flowing white powder.
Polyvinylpyrolidone K 30 is hygroscopic.
Polyvinylpyrolidone K 30's density is 1.69 g/cm³.
Polyvinylpyrolidone K 30's melting point is above 300 °C.
The boiling point of Polyvinylpyrolidone K 30 is between 90-93 °C.
Polyvinylpyrolidone K 30 is stable under normal conditions, but incompatible with strong oxidizing agents.
Polyvinylpyrolidone K 30 has good solubility in water.
However, when mixed with Ammonium Persulphate, Polyvinylpyrolidone K 30 becomes insoluble.
Polyvinylpyrolidone K 30 gels in the presence of light and Dichromate oxidizing compounds.
These dichromate compounds can be Sodium Dichromate (Sodium Bichromate) .
Polyvinylpyrolidone K 30 dissolves in many organic solvents and forms some viscosities.
The viscosity of these organic solvents varies depending on their structure.
BENEFITS OF POLYVINYLPYROLIDONE K 30:
• Stabilised emulsions
• Water soluble
• Compatible with inorganic salts
• Forms a hard film
HOME CARE FEATURES AND BENEFITS OF POLYVINYLPYROLIDONE K 30:
*Polyvinylpyrolidone K 30 acts as rheology modifier
*Polyvinylpyrolidone K 30 is a highly adhesive tablet binder
*Polyvinylpyrolidone K 30 stabilizes emulsion and structures liquid products
*Polyvinylpyrolidone K 30 provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition
*Polyvinylpyrolidone K 30 functions as binder and protective coating for enzymes
*Polyvinylpyrolidone K 30 provides surface shine enhancement
*Polyvinylpyrolidone K 30 forms hard, transparent, glossy films
PHYSICAL AND CHEMICAL PROPERTIES OF POLYVINYLPYROLIDONE K 30:
• Polyvinylpyrolidone K 30 is soluble in water (> 100 mg/ml), methanol, ethanol, alcohol, chloroform and glycerol, acetic acid.
• Polyvinylpyrolidone K 30 is insoluble in dimethyl ether, ethyl acetate, acetone, toluene, xylene, mineral oil, carbon tetrachloride.
• Polyvinylpyrolidone K 30 is a light, flaky, hygroscopic powder when dry and readily absorbs up to 40% of its weight in atmospheric water.
• In solution, Polyvinylpyrolidone K 30 has excellent wetting properties and forms films easily.
This makes Polyvinylpyrolidone K 30 good as a coating or an additive to coatings.
• Polyvinylpyrolidone K 30 is a white, free-flowing powder of high molecular weight.
• Polyvinylpyrolidone K 30 is water-soluble and has excellent film-forming and adhesive properties.
• Polyvinylpyrolidone K 30 is used as a binder in many pharmaceutical tablets; it passes through the body easily when taken orally.
• Polyvinylpyrolidone K 30 is used for the inactivation or binding of polyphenols and alkaloids produced from explants in plant tissue culture.
• If the pH of Polyvinylpyrolidone K 30 solutions is higher than 6, the viscosity will increase slightly during storage, especially at high temperatures; if the pH is lower than 7 and the concentration is lower than 30%, the solutions tend to go mouldy during storage.
The addition of a preservative can prevent mould and fungal growth during storage.
The addition of large amounts of salt will precipitate Polyvinylpyrolidone K 30 from solution.
• Polyvinylpyrolidone K 30 binds exceptionally well to polar molecules due to its polarity.
• As a food additive, Polyvinylpyrolidone K 30 is a stabiliser and has the E number E1201.
• The molecular formula of Polyvinylpyrolidone K 30 is (C 6 H 9 NO) n.
• Polyvinylpyrolidone K 30 appears as a white to slightly off-white powder.
• Polyvinylpyrolidone K 30 formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents.
• The best-known example of povidone formulations is povidone-iodine, an important disinfectant.
• Polyvinylpyrolidone K 30 is an alternative to activated carbon.
• The K number represents the average molecular weight of povidone.
Povidones with higher K values (i.e. K90) are generally not administered by injection due to their higher molecular weight. Higher molecular weights prevent renal excretion and lead to accumulation in the body.
USAGE RATE OF POLYVINYLPYROLIDONE K 30:
The usage for Polyvinylpyrolidone K 30 depends on the nature of the formulation, thus there is no exact recommended concentration.
STRENGHTS OF POLYVINYLPYROLIDONE K 30:
Polyvinylpyrolidone K 30 forms clear, hard, shiny and glossy films.
PREPARATION METHOD OF POLYVINYLPYROLIDONE K 30:
Polyvinylpyrolidone K 30 is obtained by polymerizing n-vinyl-2-pyrrolidone in the presence of a basic catalyst or N,N'-vinyltriazole, followed by purification.
STANDARD OF POLYVINYLPYROLIDONE K 30:
Polyvinylpyrolidone K 30 is obtained by polymerizing pyrrolidone and ethylene under pressure to form a vinyl pyrrolidone monomer by the action of a catalyst.
Polyvinylpyrolidone K 30 homopolymer having an average molecular weight of 3.8x 104 and a molecular formula of (C6H9NO)n, where n represents the average number of 1-vinyl-2-pyrrolidone moieties.
TRAIT OF POLYVINYLPYROLIDONE K 30:
Polyvinylpyrolidone K 30 is white to milky white powder; Odorless or slightly odorous, tasteless; With hygroscopicity.
Polyvinylpyrolidone K 30 is soluble in water, ethanol, isopropanol or chloroform, and insoluble in acetone or ether.
HOW IS POLYVINYLPYROLIDONE K 30 PRODUCED?
Polyvinylpyrrolidone (PVP) was first synthesized by BASF chemist Walter Reppe, who filed a patent for one of the derivatives of acetylene chemistry in 1939.
Different degrees of polymerization of PVP as a binder have resulted in polymers with various molecular weights.
It is usually characterized by its viscosity in aqueous solution compared to water and is expressed as a K value in the range of 10-120.
K values are obtained from viscosity measurements and calculated according to the Fikentscher formula.
Povidones with K values ≤ 30 are produced by spray drying in spheres, while povidones with higher K values are produced by drum drying in plates.
Wet granulation with povidone K25/30/90 gives harder granules with better flow properties compared to other binders, which generally have lower friability and higher bond strength.
WHAT IS IT?
Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs.
It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.
Polyvinylpyrolidone K 30 has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder.
Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents.
The k number refers to the mean molecular weight of the povidone.
Povidones with higher K-values (i.e., k90) are not usually given by injection due to their high molecular weights.
The higher molecular weights prevent excretion by the kidneys and lead to accumulation in the body.
The best-known example of povidone formulations is povidone-iodine, an important disinfectant.
PHYSICAL and CHEMICAL PROPERTIES of POLYVINYLPYROLIDONE K 30:
Physical state: Powder
Color: Beige
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 5.0 - 8 at 10 g/l at 20 °C
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
CAS Number: 9003-39-8
EC Number: Not specified
PSA: 20.31000
XLogP3: 0.69020
Appearance: Polyvinylpyrrolidone is a white powder.
Compatible with a wide range of hydrophilic and hydrophobic resins.
Density: 1.23-1.29 g/cm³
Melting Point: 160 °C
Boiling Point: >300 °C
Flash Point: 93.9ºC
Water Solubility: H2O: soluble 100mg/mL
Storage Conditions: Store at RT.
Vapor Pressure: 0.09 mmHg
Vapor Density: 3.83
Toxicity: LD50 orally in Rabbit: > 2000 mg/kg
Explosive limit: Explosive limits, vol% in air: 1.4-10
Odor: ODORLESS
pH: Between 3.0 and 7.0 (5 % solution)
Reactive Group: Amines, Phosphines, and Pyridines
Reactivity Profile: POLYVINYLPYRROLIDONE is a polymeric material and probably has low reactivity.
It reacts as a weak base.
Autoignition Temperature: 364 °C
Appearance: White to off-white powder
Odor: Odorless
Solubility: Soluble in water and various organic solvents, including alcohols
(e.g., methanol, ethanol), amides, and chlorinated solvents
pH (10% solution at 20°C): 5.0 - 8.0
Nitrogen Content: 11.5 – 12.8%
K-value: ~30
Moisture Content: Maximum 5%
Viscosity (5% solution at 25°C): 2.5 - 4.0 mPa·s
Glass Transition Temperature (Tg): Approximately 150 - 180°C
Molecular Formula / Molecular Weight: (C6H9NO)n
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Hygroscopic
CAS RN: 9003-39-8
PubChem Substance ID: 87574663
Merck Index (14): 7697
MDL Number: MFCD01076626
Molecular Formula: (C6H9NO)n
SMILES: -CC(-)N1CCCC1=O
MDL Number: MFCD01076626
Molecular Formula: (C6H9NO)n
SMILES: -CC(-)N1CCCC1=O
MDL Number: MFCD01076626
CAS: 9003-39-8
K-value: 27 to 32 (1 % w/v in water at 25°C)
K-value: 27 to 32 (1 % w/v in water at 25°C)
Chemical Name: Polyvinylpyrrolidone K30 (PVP K30)
Chemical Formula: (C6H9NO)n
Molecular Weight: 35,000-51,000 g/mol
CAS No: 9003-39-8
Aqueous pH (%5): 3.0 - 5.0
Density: 1.23-1.29 g/cm³
Melting Point: 13.9 °C
Boiling Point: 90-93 °C
Solubility: In water (> 100 mg/ml)
K value: ~30
CAS: 9003-39-8
EINECS: 1312995-182-4
Molecular Formula: (C6H9NO)n
Molar Mass: 111.143
Density: 1.69 g/cm3
Melting Point: 130℃
Boiling Point: 90-93 °C
Water Solubility: >=10 g/100 mL at 20°C
Appearance: White powder
Storage Condition: Room Temperature
Physical and Chemical Properties:
Melting Point: 130°C
Molecular weight: about 25-30000 g / mol
Physical Description: White to off white powder
Appearance Form: powder
Color: white
Odor: No data available
Odor Threshold: No data available
pH: 5,0 - 8 at 10 g/l at 20 °C
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance (Colour): White to off – white
Appearance (Form): Crystalline powder
Solubility (Turbidity): 10% aq. solution Clear
Nitrogen content (N): 11.5 – 12.5%
pH (5% aq. solution): 3.0 – 7.0
Sulphated Ash: max. 0.1%
Heavy Metals (Pb): max. 0.001%
K-value ~: 30
Vinyl pyrrolidone: max. 0.8%
Water (KF): max. 5%
FIRST AID MEASURES of POLYVINYLPYROLIDONE K 30:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of POLYVINYLPYROLIDONE K 30:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of POLYVINYLPYROLIDONE K 30:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYVINYLPYROLIDONE K 30:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of POLYVINYLPYROLIDONE K 30:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of POLYVINYLPYROLIDONE K 30:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
