Quick Search
CAS NUMBER: 9003-39-8
EC NUMBER: 201-800-4
MOLECULAR FORMULA: C6H9NO
MOLECULAR WEIGHT: 111.14
IUPAC NAME: 1-ethenylpyrrolidin-2-one
Polyvinylpyrrolidone is also commonly called polyvidone or povidone
Polyvinylpyrrolidone is a water-soluble polymer made from the monomer N-vinylpyrrolidone.
Polyvinylpyrrolidone is available in a range of molecular weights and related viscosities
Polyvinylpyrrolidone can be selected according to the desired application properties.
USES:
Medical Uses:
Polyvinylpyrrolidone is used as a binder in many pharmaceutical tablets
Polyvinylpyrrolidone simply passes through the body when taken orally.
Polyvinylpyrrolidone added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.
This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs.
Polyvinylpyrrolidone is known under the trade names Pyodine and Betadine, among a plethora of others.
Polyvinylpyrrolidone is used in pleurodesis (fusion of the pleura because of incessant pleural effusions).
For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.
Polyvinylpyrrolidone is used in some contact lenses and their packaging solutions.
Polyvinylpyrrolidone reduces friction, thus acting as a lubricant, or wetting agent, built into the lens.
Polyvinylpyrrolidone is used as a lubricant in some eye drops, e.g.
Polyvinylpyrrolidone was used as a plasma volume expander for trauma victims after the 1950s.
Polyvinylpyrrolidone is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.
Autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.
The long-term effects of crospovidone or povidone within the lung are unknown.
Technical Uses:
Polyvinylpyrrolidone is also used in many technical applications:
*as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process
*as an emulsifier and disintegrant for solution polymerization
*to increase resolution in photoresists for cathode ray tubes (CRT)
*in aqueous metal quenching
*for production of membranes, such as dialysis and water purification filters
*as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating
*as a thickening agent in tooth whitening gels
*as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation
*as an additive to Doro's RNA extraction buffer
*as a liquid-phase dispersion enhancing agent in DOSY NMR
*as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly
*as a stabilizing agent in all inorganic solar cells
Other Uses:
Polyvinylpyrrolidone binds to polar molecules exceptionally well, owing to its polarity.
This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.
Polyvinylpyrrolidone is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes.
Polyvinylpyrrolidone has also been used in contact lens solutions and in steel-quenching solutions.
Polyvinylpyrrolidone is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.
As a food additive, Polyvinylpyrrolidone is a stabilizer and has E number E1201.
Polyvinylpyrrolidone (crospovidone) is E1202.
Polyvinylpyrrolidone is also used in the wine industry as a fining agent for white wine and some beers.
In in-vitro fertilisation laboratories, Polyvinylpyrrolidone is used to slow down spermatozoa in order to capture them for e.g
In molecular biology, Polyvinylpyrrolidone can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer.
Polyvinylpyrrolidone is also exceptionally good at absorbing polyphenols during DNA purification.
Polyvinylpyrrolidone are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR.
In microscopy, Polyvinylpyrrolidone is useful for making an aqueous mounting medium
PROPERTIES:
Polyvinylpyrrolidone is soluble in water and other polar solvents.
For example, Polyvinylpyrrolidone is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).
When dry Polyvinylpyrrolidone is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water.
In solution, Polyvinylpyrrolidone has excellent wetting properties and readily forms films.
This makes Polyvinylpyrrolidone good as a coating or an additive to coatings.
A 2014 study found fluorescent properties of Polyvinylpyrrolidone and its oxidized hydrolyzate
Polyvinylpyrrolidone, commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone
Polyvinylpyrrolidone, also known as povidone or PVP, is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs.
Polyvinylpyrrolidone has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.
Polyvinylpyrrolidone has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder.
Polyvinylpyrrolidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents.
Polyvinylpyrrolidone is a nonionic, water-soluble polymer with the following features.
Polyvinylpyrrolidone can be suitable for the usage of various applications and fields.
-Soluble in various solvents (e.g.: water, alcohol, amide and chlorineated solvents)
-Heat Resistance （Tg=160-170℃）
-Highly hygroscopicity
-Good film-forming properties
-Adhesion
-Ability to form complexes
Polyvinylpyrrolidone is a water-soluble polymer obtained by polymerization of monomer N-vinylpyrrolidone.
Polyvinylpyrrolidone is an inert, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs.
These advantages enable Polyvinylpyrrolidone a versatile excipient in the formulation development of broad conventional to novel controlled delivery systems.
Polyvinylpyrrolidone has tunable properties and can be used as a brace component for gene delivery, orthopedic implants, and tissue engineering applications.
Based on different molecular weights and modified forms, Polyvinylpyrrolidone can lead to exceptional beneficial features with varying chemical properties.
Polyvinylpyrrolidone has physicochemical properties making it suitable for usage in different fields like pharmaceutical, biomedical, cosmetic, and food industry.
Polyvinylpyrrolidone is soluble in water and other polar solvents.
In water Polyvinylpyrrolidone has the useful property of Newtonian viscosity.
When dry it is a light flaky powder, which readily absorbs up to 18% of its weight in atmospheric water.
In solution, Polyvinylpyrrolidone has excellent wetting properties and readily forms films.
This makes Polyvinylpyrrolidone good as a coating or an additive to coatings
Polyvinylpyrrolidone is a member of pyrrolidin-2-ones.
Polyvinylpyrrolidone is a white powder.
Polyvinylpyrrolidone is compatible with a wide range of hydrophilic and hydrophobic resins.
PHYSICAL PROPERTIES:
-Molecular Weight: 111.14
-XLogP3: 0.4
-Exact Mass: 111.068413911
-Monoisotopic Mass: 111.068413911
-Topological Polar Surface Area: 20.3 Ų
-Physical Description: White or nearly white powder
-Color: Faintly yellow
-Form: Solid
-Odor: Odorless
-Boiling Point: 90-93 °C
-Melting Point: 13.9 °C
-Flash Point: 93 °C
-Solubility: Soluble in water and in ethanol. Insoluble in ether
-Density: 1.23-1.29
-Vapor Density: 3.83
-Vapor Pressure: 0.1 mmHg
-Autoignition Temperature: 364 °C
-Viscosity: 2.07 cP
-Chemical Classes: Plastics & Rubber -> Other Monomers
Polyvinylpyrrolidone is abbreviated as PVP, and is the polymer of vinylpyrrolidone.
According to the different degree of polymerization, it is further classified into soluble PVP and insoluble PVPP
CHEMICAL PROPERTIES:
-Hydrogen Bond Donor Count: 0
-Hydrogen Bond Acceptor Count: 1
-Rotatable Bond Count: 1
-Heavy Atom Count: 8
-Formal Charge: 0
-Complexity: 120
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes
Polyvinylpyrrolidone is also commonly called polyvidone or povidone
Polyvinylpyrrolidone is a water-soluble polymer made from the monomer N-vinylpyrrolidone.
Polyvinylpyrrolidone is available in a range of molecular weights and related viscosities
Polyvinylpyrrolidone can be selected according to the desired application properties.
Polyvinylpyrrolidone is used as a binder in many pharmaceutical tablets
Polyvinylpyrrolidone is used in some contact lenses and their packaging solutions.
Polyvinylpyrrolidone is used as a lubricant in some eye drops, e.g.
Polyvinylpyrrolidone is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes.
Polyvinylpyrrolidone has also been used in contact lens solutions and in steel-quenching solutions.
Polyvinylpyrrolidone is also exceptionally good at absorbing polyphenols during DNA purification.
Polyvinylpyrrolidone is soluble in water and other polar solvents.
Polyvinylpyrrolidone has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.
Polyvinylpyrrolidone can be suitable for the usage of various applications and fields.
Polyvinylpyrrolidone is a pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs.
Polyvinylpyrrolidone is soluble in water and other polar solvents.
Polyvinylpyrrolidone has excellent wetting properties and readily forms films.
Polyvinylpyrrolidone is a white powder.
SYNONYMS:
N-VINYL-2-PYRROLIDONE
88-12-0
1-vinylpyrrolidin-2-one
N-Vinylpyrrolidone
1-Vinyl-2-pyrrolidone
N-Vinyl-2-pyrrolidinone
POLYVINYLPYRROLIDONE
Vinylpyrrolidone
9003-39-8
1-Vinyl-2-pyrrolidinone
Povidone
1-ethenylpyrrolidin-2-one
2-Pyrrolidinone, 1-ethenyl-
N-Vinylpyrrolidinone
Polyvidone
1-Vinylpyrrolidone
Vinylbutyrolactam
Plasdone
Vinylpyrrolidinone
V-Pyrol
Luviskol
1-Vinylpyrrolidinone
Vinyl-2-pyrrolidone
25249-54-1
Polyclar AT
N-Vinyl pyrrolidone
1-Ethenyl-2-pyrrolidinone
N-Vinylpyrrolidone-2
2-Pyrrolidinone, 1-vinyl-
Poly(N-vinylpyrrolidone)
1-Vinyl-2-pyrrolidinone, monomer
Poly(1-vinyl-2-pyrrolidone)
1-vinyl-pyrrolidin-2-one
PVP-40
Poly[1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl]
2-Pyrrolidinone, 1-ethenyl-, trimer
2-Pyrrolidinone, polymers
CAS-88-12-0
Polyvinylpyrrolidine
EINECS 201-800-4
Polyvinylpyrrolidone K 90
Polyvinylpyrrolidone K-30
2-Pyrrolidinone, polymers, compd. with aluminum acetate
BRN 0110513
CCRIS 8581
PovidonePVP
vinyl pyrrolidone
Polyvinylpyrrolidon
Poly[1-(2-oxo-1-pyrrolidinyl)-1, .alpha.-hydro-.omega.-[[4-(iodo-131I)phenyl]methyl]-
UNII-76H9G81541
N-vinyl-pyrrolidone
N -vinylpyrrolidinone
1-vinyl-2-pyrrolidon
POVIDONE MONOMER
VINYLBUTYLOLACTAM
N-vinylpyrrolidin-2-one
N-vinyl pyrrolidin-2-one
N-vinyl-pyrrolidin-2-one
PVP K3O
Crospovidone ~40,000
EC 201-800-4
poly (N-vinyl pyrrolidone)
PVP K15
PVP K30
PVP-K30
Polyvinylpyrrolidone PVP K30
POVIDONE MONOMER
VINYL PYRROLIDONE (VP)
poly(1-vinylpyrrolidin-2-one)
Polyvinylpyrrolidone, cross linked
N-VINYL PYRROLIDONE
1-Vinyl-2-pyrrolidone
Polyvinylpyrrolidone
N-VINYL-2-PYRROLIDONE
Polyvinylpyrrolidone, M.W. 360.000
Polyvinylpyrrolidone, M.W. 1,300,000
2-PYRROLIDINONE, 1-ETHENYL- [HSDB]
1-Vinyl-2-pyrrolidinone, SAJ first grade, >=99.0%
3-CHLORO-5,6-DIFLUORO-1-BENZOTHIOPHENE-2-CARBONYLCHLORIDE
1-Vinyl-2-pyrrolidinone
1-Vinyl-2-pyrrolidinone, Pharmaceutical Secondary Standard; Certified Reference Material
1-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine)
