POTASSIUM ASCORBATE

Heavy Atom Count 13
Formal Charge 0
Complexity 237
Isotope Atom Count 0
Dened Atom Stereocenter Count 2
Undened Atom Stereocenter Count 0
Dened Bond Stereocenter Count 0
Undened Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes
Potassium ascorbate is a compound with formula KC6H7O6. It is the potassium salt of ascorbic acid (vitamin C) and a mineral
food additive, it has E number E303, INS number 303. Although it is not a permitted food additive in the UK or the USA, it is ap
Australia and New Zealand.
Chemical formula C6H7KO6
Molar mass 214.214 g·mol-1
Solubility in water 980 mg/mL
Shelf life is 24 months if stored in a cool and dry location. Please note that it is natural for this product to harden, clump and d
Variations in temperature and humidity will accelerate this process; therefore, it should be transported and stored in a cool, d
The Vitamin C and Potassium content will remain within specication during the listed shelf life. Product will likely require mil
A ne tasting, eervescent Potassium Ascorbate drink containing 700 mg of potassium and 4 grams of Vitamin C, and that's a
DON'T make this product your only source of Vitamin C since 20 drinks/day (1/2 bottle) can be fatal to an adult!
If you plan taking over two rounded teaspoons per day, please consult your doctor, especially if you have kidney problems.
Serving Size, One Teaspoon. 8 oz Will Make 43 Potassium Ascorbate Drinks.
Oxidative processes linked to the presence of free radicals are involved in the impetus and development of cancer. Free radic
reason for the mechanism of oxidative stress. Living organisms tend to maintain a constant level of the concentration of thes
to ensure normal biological processes.
The described mechanism turns out to be very dangerous for the cell when:
it activates a rapid transfer of calcium from intracellular deposits (mitochondria), that could be responsible for mitogenic activ
duplication);
it allows a considerable transport of glucose into the cytoplasm (together with sodium, SGLUT symport) with a speed that incr
the increasingly greater alteration of the sodium/potassium pump (which is the only active control element of the two electro
These processes lead to a modication in cell respiration, with a decrease of oxidative phosphorylation and a substantial incre
The production of lactic acids, formed by pyruvate reduction, is also increased. Moreover, this pyruvate reduction prevents th
phase of the mitosis and its steady decrease in the cytoplasm (for the conversion into lactic acid) takes this block on mitosis a
cell towards uncontrolled proliferation.
So we have a modication of the intracellular pH that tends to become lightly alkaline, and a modication of the cellular respi
signicant alteration of the Krebs cycle.
These facts together tend to result in an alteration in form and action of proteins and cytoplasmic enzymes, leading to a polym
and a transfer of incorrect information between the ‘periphery' and the ‘operative center' (DNA). This leads to the mutation of
and carcinogenesis.
In conclusion, the following hypothesis on which we are working now is that degeneration does not arise from a direct damag
DNA, but from a problem in the cytoplasm, which means the damage occurs at the peripherical level (cell membrane). This wo
that operation of DNA can be strongly inuenced by various components of the same cellular environment as well as by cell-t
From experience and data of Dr. Pantellini rst and those of the Foundation now it seems that potassium ascorbate, also and
newest formula with ribose, interferes with this process in a major way; it protects the cell against oxidative stress and inhibit
proliferation mechanism.
These facts can be related to the transporting (‘carrier') characteristics of ascorbic acid for potassium (and with the catalytic ac
the ‘new' formula) as a result from its heterocyclic structure, together with its antioxidant action.
The compound's action is related to the characteristics of potassium as ‘guiding' cation and metabolic regulator at intracellula
‘carrier' action of vitamin C, which in this specic case performs a similar function to that of the sodium/potassium pump.
The release of potassium inside a cancerous cell can provoke a corresponding runo of sodium (hence glucose) in the intrace
environment. In this way we can obtain:
a new modication of the local, intracellular pH;
a rapid decrease of nutritional reserves reducing glycolysis and re-establishing the potential block on mitosis. Thus, it seems p
the uncontrolled proliferation process.
Furthermore, potassium ascorbate can eectively serve on the level of prevention, maintaining constant intracellular potassiu
as previously explained, the imbalance of these intracellular levels with the ‘intrusion' of sodium from extracellular areas wou
for (or at least highly involved in) the chain of events that could lead to transformation of a cell into a neoplastic cell. Preventiv
potassium ascorbate therefore has the objective to protect the cell from the risk of degeneration.
In recent years, the formula has been enriched with ribose which performs a catalytic activity, increasing the speed of the pro
potassium is transferred into cells. For further information, please go to the corresponding section on this website.
Preventive intake of the compound by adults generally consists of taking one dose per day, preferably in the morning on emp
minutes before breakfast (unless otherwise indicated based on the evaluation of blood test/parameters).
In the presence of an oncologic disease it is generally recommended to take 3 daily doses (in the morning on empty stomach,
before breakfast; and 45 minutes before lunch and dinner).
It is always advisable to have an assessment made by a competent person in order to be able to suggest the most appropriat
situation.
Very Powerful Blended Anti-Oxidant
Helps enhance overall immune function
Excellent source of Buered Vitamin C
Daily calcium source with anti-aging properties
Potassium Ascorbate Buered Vitamin C Powder, otherwise known as Ascorbic Acid, is a buered Vitamin C powder in a pure
buering makes the Vitamin C more easy on the digestive system and provides the most eective form of the Vitamin due to
enhancing properties. This Ascorbic Acid is 100% Blended Vitamin C with Potassium in a ne powder and may be added to foo
or smoothies and green drinks. It is a pure white powder and has no llers, additives or preservatives. Various sizes available
and quantity discounts available on bulk-packed foods and food powders for commercial uses. Only the highest quality Blend
ingredients are sourced through family-owned Prescribed For Life Nutrition.
While surgery is the denitive treatment for early-stage melanoma, the current therapies against advanced melanoma do not
eective, long-lasting control of the lesions and a satisfactory impact on patient survival. Thus, research is also focused on nov
that could potentiate the current therapies. In the present study, we evaluated the eect of potassium ascorbate with ribose (
the human melanoma cell line, A375, in 2D and 3D models. In the 2D model, in line with the current literature, the pharmacol
with PAR decreased cell proliferation and viability. In addition, an increase in Connexin 43 mRNA and protein was observed. T
was conrmed in PAR-treated melanoma cells cultured in 3D, where an increase in functional gap junctions and a higher sphe
were observed. Moreover, in the 3D model, a remarkable decrease in the size and volume of spheroids was observed, further
treatment ecacy observed in the 2D model. In conclusion, our results suggest that PAR could be used as a safe adjuvant app
to conventional therapies for the treatment of melanoma.