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Potassium Salicylate is the monopotassium salt of salicylic acid and consists of a potassium cation associated with the 2-hydroxybenzoate anion.
Potassium Salicylate functions as a water-soluble salicylate source, pharmaceutical intermediate, cosmetic preservative, analytical reagent, biochemical research compound, and specialty chemical intermediate.
Potassium Salicylate is used in regulated pharmaceutical and cosmetic formulations, laboratory analysis, salicylate research, coordination chemistry, plant-science studies, and specialty synthesis.
CAS Number: 578-36-9
EC Number: 209-421-6
Molecular Formula: C7H5KO3
Molecular Weight: 176.21 g/mol
Synonyms: Potassium Salicylate, Potassium salicylate, Salicylic Acid Potassium Salt, Salicylic Acid Monopotassium Salt, Salicylic Acid 1-Potassium Salt, Potassium 2-Hydroxybenzoate, Potassium o-Hydroxybenzoate, Potassium Orthohydroxybenzoate, Benzoic Acid 2-Hydroxy Monopotassium Salt, Benzoic Acid 2-Hydroxy Potassium Salt, Benzoic Acid 2-Hydroxy Potassium Salt (1:1), 2-Hydroxybenzoic Acid Potassium Salt, 2-Hydroxybenzoate Potassium Salt, Monopotassium Salicylate, Potassium Salt of Salicylic Acid, Potassium Salicylate Anhydrous, Potassium Salicylate Powder, Potassium Salicylate Crystals, Pharmaceutical-Grade Potassium Salicylate, Cosmetic-Grade Potassium Salicylate, Laboratory-Grade Potassium Salicylate, Analytical-Grade Potassium Salicylate, Research-Grade Potassium Salicylate, Potassium Salicylate Preservative, Water-Soluble Salicylate Salt, Potassium Hydroxybenzoate, Salicylate Potassium Salt, K Salicylate, C7H5KO3, UNII K91YT16P5M, K91YT16P5M, NSC Potassium Salicylate, N02BA12, QN02BA12, MFCD00020256
APPLICATIONS
Potassium Salicylate is used as a water-soluble source of salicylate ions.
Potassium Salicylate is used where salicylic acid itself has insufficient aqueous solubility.
Potassium Salicylate is used to introduce salicylate functionality into aqueous chemical systems.
Potassium Salicylate is used when a potassium counterion is preferred over sodium, ammonium, or organic amine counterions.
Potassium Salicylate is used as a pharmaceutical chemical intermediate.
Potassium Salicylate is used in the development of regulated salicylate-containing pharmaceutical products.
Potassium Salicylate is used in pharmaceutical research involving analgesic and antipyretic salicylates.
Potassium Salicylate is used only in pharmaceutical grades meeting applicable compendial and regulatory requirements.
Potassium Salicylate is used historically as a soluble salicylate medicinal ingredient.
Potassium Salicylate is used in research concerning non-narcotic analgesic compounds.
Potassium Salicylate is used in studies of salicylate-associated anti-inflammatory mechanisms.
Potassium Salicylate is used in pharmacological experiments requiring a non-acetylated salicylate salt.
Potassium Salicylate is used in comparative studies of aspirin and non-acetylated salicylates.
Potassium Salicylate is used to investigate differences between salicylic acid salts and acetylsalicylic acid.
Potassium Salicylate is used in research examining salicylate absorption, distribution, and elimination.
Potassium Salicylate is used in controlled laboratory studies rather than for unsupervised medicinal use.
Potassium Salicylate is used in pharmaceutical formulation research.
Potassium Salicylate is used in aqueous dosage-form development when high salicylate solubility is required.
Potassium Salicylate is used in experimental oral-liquid and solution formulations.
Potassium Salicylate is used after stability, taste, compatibility, and toxicological evaluation.
Potassium Salicylate is used in veterinary pharmaceutical research.
Potassium Salicylate is used in studies classified under veterinary salicylic-acid derivatives.
Potassium Salicylate is used in regulated veterinary products only where specifically authorized.
Potassium Salicylate is used under professional veterinary and pharmaceutical controls.
Potassium Salicylate is used as a cosmetic preservative where permitted by regional regulations.
Potassium Salicylate is used to support the microbiological stability of selected cosmetic products.
Potassium Salicylate is used in preservation systems designed for compatible aqueous formulations.
Potassium Salicylate is used only after preservative-efficacy testing of the finished cosmetic product.
Potassium Salicylate is used in facial cleansers where a water-soluble salicylate ingredient is required.
Potassium Salicylate is used in cosmetic toners after formulation and irritation testing.
Potassium Salicylate is used in rinse-off skin-care formulations.
Potassium Salicylate is used at concentrations consistent with applicable cosmetic regulations.
Potassium Salicylate is used in skin-conditioning formulations.
Potassium Salicylate is used in products designed to improve the appearance of rough skin.
Potassium Salicylate is used in formulations requiring a soluble alternative to free soluble alternative to free salicylic acid.
Potassium Salicylate is used only when the finished product is formulated to be non-irritating.
Potassium Salicylate is used in cosmetic formulations intended for oily skin.
Potassium Salicylate is used in selected clarifying skin-care products.
Potassium Salicylate is used in cosmetic products designed for controlled salicylate delivery.
Potassium Salicylate is used after evaluation of finished-product pH and free salicylic-acid concentration.
Potassium Salicylate is used in scalp-care formulations where legally permitted.
Potassium Salicylate is used in selected shampoos and scalp-cleansing products.
Potassium Salicylate is used in hair-care formulations requiring a water-soluble salicylate component.
Potassium Salicylate is used after testing compatibility with surfactants, conditioning agents, and preservatives.
Potassium Salicylate is used in cosmetic creams and lotions after emulsion-compatibility evaluation.
Potassium Salicylate is used primarily in the aqueous phase of compatible emulsions.
Potassium Salicylate is used where clear dissolution is required before emulsification.
Potassium Salicylate is used after evaluating its effect on viscosity, color, odor, and emulsion stability.
Potassium Salicylate is used in water-based gels.
Potassium Salicylate is used in hydrogel formulations after polymer-compatibility testing.
Potassium Salicylate is used in clear cosmetic systems where insoluble salicylic-acid particles are undesirable.
Potassium Salicylate is used after determining its effect on gel structure and electrolyte sensitivity.
Potassium Salicylate is used in deodorant formulations where its use is permitted.
Potassium Salicylate is used in roll-on and aqueous deodorant systems after compatibility testing.
Potassium Salicylate is used in preservation packages containing complementary antimicrobial ingredients.
Potassium Salicylate is used only after finished-product challenge testing.
Potassium Salicylate is used as one component of multi-ingredient cosmetic preservation systems.
Potassium Salicylate is used with compatible preservatives when broader antimicrobial protection is required.
Potassium Salicylate is used with chelating agents and pH-control ingredients in optimized formulations.
Potassium Salicylate is not assumed to provide adequate preservation without microbiological validation.
Potassium Salicylate is used as a chemical intermediate for salicylic-acid derivatives.
Potassium Salicylate is used as a reactive salicylate source in aqueous synthesis.
Potassium Salicylate is used in salt-exchange reactions.
Potassium Salicylate is used in reactions requiring the deprotonated carboxylate form of salicylic acid.
Potassium Salicylate is used to prepare other metal salicylates through metathesis reactions.
Potassium Salicylate is used as a precursor for calcium, magnesium, zinc, copper, and iron salicylate research compounds.
Potassium Salicylate is used in coordination-chemistry experiments involving salicylate ligands.
Potassium Salicylate is used to investigate metal-carboxylate and metal-phenolate interactions.
Potassium Salicylate is used in the synthesis of salicylate coordination complexes.
Potassium Salicylate is used as a ligand source for transition-metal chemistry.
Potassium Salicylate is used in research on mononuclear and polynuclear metal complexes.
Potassium Salicylate is used in crystallographic studies of metal-salicylate structures.
Potassium Salicylate is used in the preparation of copper-salicylate complexes.
Potassium Salicylate is used in the preparation of iron-salicylate complexes.
Potassium Salicylate is used in the preparation of cobalt- and nickel-salicylate research compounds.
Potassium Salicylate is used after controlling pH, stoichiometry, temperature, and counterions.
Potassium Salicylate is used in analytical chemistry as a soluble salicylate reagent.
Potassium Salicylate is used in qualitative and quantitative tests involving salicylate ions.
Potassium Salicylate is used to prepare standard salicylate solutions.
Potassium Salicylate is used in analytical work at a purity appropriate to the measurement method.
Potassium Salicylate is used in colorimetric analysis involving ferric ions.
Potassium Salicylate is used to form colored iron-salicylate complexes.
Potassium Salicylate is used in demonstrations of ligand-to-metal complex formation.
Potassium Salicylate is used in method development for spectrophotometric salicylate determination.
Potassium Salicylate is used as a reference substance in ultraviolet-visible spectroscopy.
Potassium Salicylate is used to study the absorption behavior of salicylate ions.
Potassium Salicylate is used to examine changes in salicylate spectra with pH and metal complexation.
Potassium Salicylate is used in instrument-calibration and method-validation studies when technically appropriate.
Potassium Salicylate is used in infrared and Raman spectroscopic research.
Potassium Salicylate is used to identify carboxylate and phenolic vibrational bands.
Potassium Salicylate is used in comparative studies of salicylic acid and its salts.
Potassium Salicylate is used to investigate ionic bonding and crystal structure.
Potassium Salicylate is used as an analytical reference in chromatographic methods.
Potassium Salicylate is used in high-performance liquid chromatography method development.
Potassium Salicylate is used in ion chromatography and capillary-electrophoresis research.
Potassium Salicylate is used after establishing appropriate reference-standard purity and traceability.
Potassium Salicylate is used in liquid-chromatography mass-spectrometry research.
Potassium Salicylate is used to prepare aqueous salicylate calibration solutions.
Potassium Salicylate is used in validation of salicylate extraction and detection methods.
Potassium Salicylate is used in pharmaceutical, biological, and environmental analytical studies.
Potassium Salicylate is used in electrochemical sensor development.
Potassium Salicylate is used as a salicylate analyte during electrode testing.
Potassium Salicylate is used to calibrate experimental salicylate-sensitive detection systems.
Potassium Salicylate is used to study selectivity against benzoate, acetate, and related anions.
Potassium Salicylate is used in biosensor research.
Potassium Salicylate is used in enzyme-based salicylate-detection systems.
Potassium Salicylate is used to evaluate portable and field-deployable analytical devices.
Potassium Salicylate is used as a controlled salicylate source in calibration and recovery experiments.
Potassium Salicylate is used in biochemical research.
Potassium Salicylate is used to investigate cellular responses to salicylate ions.
Potassium Salicylate is used in enzyme-inhibition studies.
Potassium Salicylate is used in controlled experiments examining salicylate-associated signaling pathways.
Potassium Salicylate is used in protein-binding studies.
Potassium Salicylate is used to investigate interactions between salicylates and serum proteins.
Potassium Salicylate is used in equilibrium-dialysis and spectroscopic binding experiments.
Potassium Salicylate is used in biochemical systems after ionic-strength and pH adjustment.
Potassium Salicylate is used in pharmacokinetic research.
Potassium Salicylate is used to prepare salicylate-containing analytical samples.
Potassium Salicylate is used in method validation for salicylate determination in biological matrices.
Potassium Salicylate is used in controlled studies requiring accurately prepared aqueous concentrations.
Potassium Salicylate is used in toxicology research involving salicylates.
Potassium Salicylate is used in studies of dose-dependent salicylate effects.
Potassium Salicylate is used to investigate biomarkers associated with salicylate exposure.
Potassium Salicylate is used only under approved laboratory protocols.
Potassium Salicylate is used in plant-physiology research.
Potassium Salicylate is used as a soluble source of salicylate in experimental plant systems.
Potassium Salicylate is used in studies of plant defense signaling.
Potassium Salicylate is used to investigate plant responses to biological and environmental stress.
Potassium Salicylate is used in seed-treatment research.
Potassium Salicylate is used in experimental seed-priming solutions.
Potassium Salicylate is used to study germination and early seedling responses.
Potassium Salicylate is used only at experimentally validated concentrations.
Potassium Salicylate is used in plant-cell and tissue-culture research.
Potassium Salicylate is used to modify salicylate concentration in culture media.
Potassium Salicylate is used in experiments involving pathogen-response pathways.
Potassium Salicylate is used after controlling potassium concentration and medium pH.
Potassium Salicylate is used in agricultural research formulations.
Potassium Salicylate is used to investigate the effect of salicylate salts on crop stress tolerance.
Potassium Salicylate is used in greenhouse and field research under controlled protocols.
Potassium Salicylate is not used as a general agricultural product without regulatory authorization.
Potassium Salicylate is used in microbiological research.
Potassium Salicylate is used to study microbial responses to aromatic carboxylate salts.
Potassium Salicylate is used in experiments involving salicylate metabolism.
Potassium Salicylate is used in culture media only after compatibility with the organism and method is established.
Potassium Salicylate is used in environmental-analysis research.
Potassium Salicylate is used as a calibration compound for salicylate detection in water.
Potassium Salicylate is used in biodegradation and transformation studies.
Potassium Salicylate is used to investigate the environmental behavior of soluble salicylate salts.
Potassium Salicylate is used in photochemical research.
Potassium Salicylate is used to study ultraviolet absorption and photochemical transformation.
Potassium Salicylate is used in research comparing protonated and ionized salicylic-acid species.
Potassium Salicylate is used in controlled irradiation experiments.
Potassium Salicylate is used in fluorescence research.
Potassium Salicylate is used in studies of salicylate emission and quenching.
Potassium Salicylate is used to investigate metal-ion effects on salicylate fluorescence.
Potassium Salicylate is used in analytical method development involving optical detection.
Potassium Salicylate is used in crystal-growth research.
Potassium Salicylate is used to study ionic crystal formation from aqueous solutions.
Potassium Salicylate is used in investigations of hydration, polymorphism, and lattice structure.
Potassium Salicylate is used in materials-science research after controlled purification.
Potassium Salicylate is used in supramolecular chemistry.
Potassium Salicylate is used to study hydrogen bonding and cation-anion interactions.
Potassium Salicylate is used in host-guest and ion-pairing experiments.
Potassium Salicylate is used in solution and solid-state studies of aromatic hydroxycarboxylates.
Potassium Salicylate is used in metal-organic material research.
Potassium Salicylate is used as an aromatic carboxylate ligand source.
Potassium Salicylate is used in the preparation of coordination polymers.
Potassium Salicylate is used in experimental materials after structural and thermal characterization.
Potassium Salicylate is used in ion-exchange research.
Potassium Salicylate is used as a soluble aromatic anion in resin-performance studies.
Potassium Salicylate is used to evaluate adsorption and desorption behavior.
Potassium Salicylate is used in water-treatment research rather than as a universal treatment chemical.
Potassium Salicylate is used in adsorption studies.
Potassium Salicylate is used as a model aromatic organic salt.
Potassium Salicylate is used to test activated carbon, polymeric adsorbents, and mineral sorbents.
Potassium Salicylate is used to investigate the effects of pH, ionic strength, and competing solutes.
Potassium Salicylate is used in membrane-separation research.
Potassium Salicylate is used as a model salicylate solute.
Potassium Salicylate is used to study nanofiltration and ion-rejection behavior.
Potassium Salicylate is used in laboratory systems after membrane-compatibility testing.
Potassium Salicylate is used in solubility and thermodynamic studies.
Potassium Salicylate is used to investigate alkali-metal hydroxybenzoate solubility.
Potassium Salicylate is used in measurements of activity coefficients and ionic interactions.
Potassium Salicylate is used in aqueous and mixed-solvent equilibrium research.
Potassium Salicylate is used in acid-base equilibrium studies.
Potassium Salicylate is used to investigate salicylic-acid dissociation.
Potassium Salicylate is used to prepare buffered salicylate systems.
Potassium Salicylate is used in educational demonstrations of salt hydrolysis and protonation.
Potassium Salicylate is used in chemical-education laboratories.
Potassium Salicylate is used to demonstrate preparation of salts from weak acids.
Potassium Salicylate is used to compare the solubility of salicylic acid with its potassium salt.
Potassium Salicylate is used to demonstrate precipitation of salicylic acid after acidification.
Potassium Salicylate is used as a precursor for recovering salicylic acid.
Potassium Salicylate is used in acidification reactions that regenerate free salicylic acid.
Potassium Salicylate is used in purification demonstrations based on salt formation and reprecipitation.
Potassium Salicylate is used where controlled conversion between soluble and less-soluble forms is beneficial.
Potassium Salicylate is used in synthesis of salicylate esters after conversion or activation.
Potassium Salicylate is used as a starting salicylate source for specialty organic reactions.
Potassium Salicylate is used in laboratory synthesis of substituted salicylate compounds.
Potassium Salicylate is used after selecting reagents compatible with the potassium carboxylate.
Potassium Salicylate is used in synthesis of salicylamide derivatives.
Potassium Salicylate is used in research involving activated salicylic-acid intermediates.
Potassium Salicylate is used in medicinal-chemistry studies involving the salicylate scaffold.
Potassium Salicylate is used as an intermediate rather than as evidence of biological suitability of the final derivative.
Potassium Salicylate is used in specialty dye and colorant research.
Potassium Salicylate is used as an aromatic hydroxycarboxylate building block.
Potassium Salicylate is used in coupling and substitution studies after suitable activation.
Potassium Salicylate is used where aqueous salicylate handling offers a processing advantage.
Potassium Salicylate is used in quality-control laboratories.
Potassium Salicylate is used for identity, purity, water-content, and assay testing.
Potassium Salicylate is used to validate analytical methods for incoming raw materials.
Potassium Salicylate is used as a retained reference sample in regulated manufacturing environments.
Potassium Salicylate is used in pharmaceutical quality-control testing.
Potassium Salicylate is used to evaluate salicylate assay methods.
Potassium Salicylate is used in impurity and degradation studies.
Potassium Salicylate is used according to validated analytical procedures.
Potassium Salicylate is used in cosmetic raw-material testing.
Potassium Salicylate is used to verify identity and concentration in preservation systems.
Potassium Salicylate is used in stability studies of salicylate-containing formulations.
Potassium Salicylate is used after evaluating changes in pH, color, odor, and microbial protection.
Potassium Salicylate is used in commercial products only after grade-specific qualification.
Potassium Salicylate is used according to applicable pharmaceutical, cosmetic, chemical, or laboratory requirements.
Potassium Salicylate is used at concentrations established through performance and safety testing.
Potassium Salicylate is used according to the current technical data sheet, safety data sheet, and regional regulations.
DESCRIPTION
Potassium Salicylate is an aromatic hydroxycarboxylate salt.
Potassium Salicylate is the monopotassium salt of salicylic acid.
Potassium Salicylate contains one potassium cation and one 2-hydroxybenzoate anion.
Potassium Salicylate retains the phenolic hydroxyl group of salicylic acid.
Potassium Salicylate has the molecular formula C7H5KO3.
Potassium Salicylate has a molecular weight of approximately 176.21 g/mol.
Potassium Salicylate has CAS number 578-36-9.
Potassium Salicylate has EC number 209-421-6.
Potassium Salicylate is chemically named potassium 2-hydroxybenzoate.
Potassium Salicylate is also named benzoic acid, 2-hydroxy-, monopotassium salt.
Potassium Salicylate is an achiral ionic compound.
Potassium Salicylate is structurally related to salicylic acid, sodium salicylate, and other salicylate salts.
Potassium Salicylate is generally supplied as a white to off-white solid.
Potassium Salicylate may be supplied as crystals, crystalline powder, or technical powder.
Potassium Salicylate is normally odorless or has only a faint characteristic odor.
Potassium Salicylate appearance can vary slightly with purity, hydration, and storage conditions.
Potassium Salicylate is very soluble in water.
Potassium Salicylate is substantially more water soluble than free salicylic acid.
Potassium Salicylate is also reported to be soluble in alcohol.
Potassium Salicylate aqueous solubility enables preparation of concentrated salicylate solutions.
Potassium Salicylate dissociates in water into potassium and salicylate ions.
Potassium Salicylate aqueous solutions contain the deprotonated carboxylate form of salicylic acid.
Potassium Salicylate solution behavior depends on concentration, temperature, ionic strength, and pH.
Potassium Salicylate can be converted back to salicylic acid through acidification.
Potassium Salicylate is commonly prepared by neutralizing salicylic acid with potassium hydroxide.
Potassium Salicylate may also be prepared using potassium carbonate or another suitable potassium base.
Potassium Salicylate production requires control of stoichiometry to obtain the monopotassium salt.
Potassium Salicylate is isolated through concentration, crystallization, drying, and milling.
Potassium Salicylate retains a free phenolic hydroxyl group.
Potassium Salicylate contains an aromatic benzene ring.
Potassium Salicylate contains an ionized carboxylate group.
Potassium Salicylate can interact with metal ions through oxygen-donor sites.
Potassium Salicylate can form coordination complexes with transition metals.
Potassium Salicylate salicylate ions may coordinate through carboxylate oxygen atoms.
Potassium Salicylate may also participate in chelation involving the adjacent phenolic group.
Potassium Salicylate coordination behavior depends strongly on pH and metal identity.
Potassium Salicylate provides salicylate ions associated with characteristic ultraviolet absorption.
Potassium Salicylate forms colored complexes with certain metal ions.
Potassium Salicylate can therefore be used in spectroscopic and colorimetric research.
Potassium Salicylate optical behavior changes after protonation or metal coordination.
Potassium Salicylate is more ionic and hydrophilic than esterified salicylates.
Potassium Salicylate normally partitions preferentially into aqueous phases.
Potassium Salicylate is less suitable for incorporation into nonpolar oils without a compatible solvent or delivery system.
Potassium Salicylate formulation behavior differs significantly from oil-soluble salicylate esters.
Potassium Salicylate is classified within salicylic acid and derivative pharmacological categories.
Potassium Salicylate has historically been associated with analgesic and antipyretic salicylates.
Potassium Salicylate pharmacological effects arise primarily from the salicylate moiety.
Potassium Salicylate medical use requires professional control because excessive salicylate exposure can be harmful.
Potassium Salicylate is listed as a cosmetic preservative in relevant ingredient inventories.
Potassium Salicylate cosmetic safety depends on concentration, formulation, irritation potential, and sensitization potential.
Potassium Salicylate cosmetic products must comply with regional restrictions.
Potassium Salicylate should not be assumed to provide complete preservation without challenge testing.
Potassium Salicylate may affect formulation pH and electrolyte balance.
Potassium Salicylate can reduce the viscosity of electrolyte-sensitive polymer gels.
Potassium Salicylate can interact with cationic surfactants and polymers.
Potassium Salicylate must therefore be tested in the complete formulation.
Potassium Salicylate concentrated aqueous solutions may crystallize when cooled or evaporated.
Potassium Salicylate crystallization depends on concentration, temperature, and other dissolved ingredients.
Potassium Salicylate should be fully dissolved before final formulation adjustment.
Potassium Salicylate solutions should be inspected for precipitation during stability testing.
Potassium Salicylate is generally stable when stored dry in sealed packaging.
Potassium Salicylate should be protected from moisture and contamination.
Potassium Salicylate should be protected from strong acids and strong oxidizing agents.
Potassium Salicylate should be stored away from excessive heat and direct sunlight.
Potassium Salicylate has low volatility under normal conditions.
Potassium Salicylate does not have a meaningful conventional flash point as a nonvolatile inorganic-organic salt.
Potassium Salicylate may decompose rather than boil cleanly when strongly heated.
Potassium Salicylate thermal decomposition may produce carbon oxides, potassium-containing residues, and irritating fumes.
Potassium Salicylate powder can generate airborne dust during transfer.
Potassium Salicylate dust may irritate the eyes and respiratory tract.
Potassium Salicylate is classified by some suppliers as harmful if swallowed.
Potassium Salicylate is classified by some suppliers as causing serious eye irritation.
Potassium Salicylate ingestion can produce systemic salicylate exposure.
Potassium Salicylate significant accidental ingestion requires prompt medical assessment.
Potassium Salicylate should be kept away from food, beverages, and animal feed unless specifically manufactured and authorized for such use.
Potassium Salicylate should be handled only by trained personnel.
Potassium Salicylate quality is commonly assessed by assay.
Potassium Salicylate quality may also be assessed by water content, appearance, pH, salicylic-acid content, and inorganic impurities.
Potassium Salicylate analytical and pharmaceutical grades generally have tighter impurity specifications than technical grades.
Potassium Salicylate specifications should be confirmed from the certificate of analysis.
Potassium Salicylate may be supplied in anhydrous or moisture-containing form.
Potassium Salicylate exact water content depends on manufacturing and storage.
Potassium Salicylate melting or decomposition behavior depends on hydration and purity.
Potassium Salicylate thermal values should be taken from the selected grade’s current technical documentation.
Potassium Salicylate is distinct from potassium acetylsalicylate.
Potassium Salicylate is distinct from methyl salicylate and other salicylic-acid esters.
Potassium Salicylate is distinct from potassium sorbate and potassium benzoate.
Potassium Salicylate should be identified using its complete name and CAS number.
Potassium Salicylate is available in research, analytical, cosmetic, pharmaceutical, and technical grades.
Potassium Salicylate grades differ in assay, color, moisture, particle size, and impurity profile.
Potassium Salicylate regulated applications require appropriate documentation and purity.
Potassium Salicylate should always be selected according to its intended use.
PROPERTIES
Chemical Name: Potassium Salicylate
IUPAC Name: Potassium 2-hydroxybenzoate
Alternative Chemical Name: Benzoic acid, 2-hydroxy-, monopotassium salt
CAS Number: 578-36-9
EC Number: 209-421-6
PubChem CID: 23664627
UNII: K91YT16P5M
MDL Number: MFCD00020256
WHO ATC Code: N02BA12
WHO ATCvet Code: QN02BA12
Chemical Family: Salicylates and aromatic hydroxycarboxylate salts
Chemical Type: Monopotassium salt of salicylic acid
Molecular Formula: C7H5KO3
Molecular Weight: 176.21 g/mol
Salicylate Anion Formula: C7H5O3−
Potassium Content by Weight: Approximately 22.19%
Physical Form: Solid
Typical Appearance: White to off-white crystalline solid or powder
Odor: Odorless or faint characteristic odor
Purity: Grade dependent; laboratory products are commonly supplied around 95–99%
Water Solubility: Very soluble
Alcohol Solubility: Soluble
Nonpolar-Solvent Solubility: Low
Aqueous Behavior: Dissociates into potassium and salicylate ions
Solution pH: Concentration and grade dependent
Density: Grade and physical-form dependent
Melting or Decomposition Point: Grade dependent; refer to the current supplier specification
Boiling Point: Not considered a reliable practical specification because the salt may decompose
Vapor Pressure: Negligible at ambient temperature
Volatility: Low
Flash Point: Not conventionally applicable to the solid salt
Combustibility: May decompose or burn under severe fire conditions
Acidification Product: Salicylic acid
Primary Functions: Water-soluble salicylate source, pharmaceutical intermediate, cosmetic preservative, analytical reagent, ligand source, and research compound
Pharmaceutical Classification: Salicylic acid and derivatives
Cosmetic Function: Preservative and formulation-dependent skin or hair conditioning use
Analytical Uses: Salicylate standards, spectrophotometry, chromatography, sensor calibration, and coordination chemistry
Research Uses: Pharmacology, biochemistry, toxicology, plant science, materials science, and environmental analysis
FIRST AID
Inhalation:
Move the affected person to fresh air.
Obtain medical advice if coughing, respiratory irritation, or discomfort persists.
Skin Contact:
Wash thoroughly with soap and water.
Remove contaminated clothing and seek advice if irritation develops.
Eye Contact:
Rinse cautiously with clean water for at least 15 minutes.
Remove contact lenses if easy to do and obtain prompt medical attention.
Ingestion:
Rinse the mouth and do not induce vomiting.
Contact a physician or poison center promptly because systemic salicylate exposure may occur.
Note to Physicians:
Treat symptomatically and monitor for salicylate-related effects after significant exposure.
Consult the current product-specific safety data sheet.
HANDLING AND STORAGE
Handling:
Avoid generating dust and wear gloves, protective clothing, and safety glasses.
Do not eat, drink, or smoke while handling the material.
Ventilation:
Provide general ventilation and local dust extraction at charging and transfer points.
Use suitable particulate respiratory protection when dust cannot be adequately controlled.
Storage:
Store in tightly sealed original packaging in a cool, dry, well-ventilated place.
Protect the product from moisture, strong acids, oxidizing agents, heat, and contamination.
Spill and Leak Procedures:
Collect spilled material using dust-controlled mechanical methods or an appropriate vacuum.
Prevent uncontrolled release into drains and place recovered material in a labeled container.
Handling Precautions:
Wash thoroughly after handling and keep the material away from unauthorized personnel.
Follow the current supplier technical data sheet, safety data sheet, and applicable pharmaceutical or cosmetic regulations.
