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Potassium Thioglycolate is the potassium salt of thioglycolic acid used as a reducing agent, depilatory active, hair-waving ingredient, and chemical intermediate, and Potassium Thioglycolate is valued for its ability to reduce disulfide bonds in keratin-containing materials.
Potassium Thioglycolate is commonly used in depilatory creams, hair waving products, hair straightening systems, textile auxiliaries, leather processing, and specialty chemical formulations where controlled thioglycolate reducing activity is required.
Potassium Thioglycolate is typically supplied as an aqueous solution or white to off-white solid depending on grade, and Potassium Thioglycolate performance depends on active content, pH, free thioglycolic acid level, odor control, stabilizer system, dosage, and regulatory limits in the target application.
CAS Number: 34452-51-2
EC Number: 252-036-5
Molecular Formula: C2H3KO2S
Molecular Weight: 130.21 g/mol
Synonyms: Potassium Thioglycolate, Thioglycolic Acid Potassium Salt, Potassium Mercaptoacetate, Potassium 2-Mercaptoacetate, Potassium Sulfanylacetate, Mercaptoacetic Acid Potassium Salt, Potassium Thioglycolate Solution, Potassium Thioglycolate Cosmetic Grade, Potassium Thioglycolate Depilatory Agent, Potassium Thioglycolate Reducing Agent, Thioglycolate Salt, Keratin Reducing Agent, Potassium Thioglycolate, Thioglycolic Acid Potassium Salt, Potassium Mercaptoacetate, Potassium 2-Mercaptoacetate, Potassium Sulfanylacetate, Potassium Thioacetate Glycolate, Mercaptoacetic Acid Potassium Salt, 2-Mercaptoacetic Acid Potassium Salt, Sulfanylacetic Acid Potassium Salt, Potassium Thioglycollate, Potassium Mercaptoacetate Solution, Potassium Thioglycolate Solution, Potassium Thioglycolate Liquid, Potassium Thioglycolate Cosmetic Grade, Potassium Thioglycolate Hair Removal Grade, Potassium Thioglycolate Depilatory Grade, Potassium Thioglycolate Perming Agent, Potassium Thioglycolate Hair Waving Agent, Potassium Thioglycolate Reducing Agent, Potassium Thioglycolate Chemical Grade, Potassium Thioglycolate Technical Grade, Potassium Thioglycolate Industrial Grade, Potassium Thioglycolate High Purity, High Purity Potassium Thioglycolate, Potassium Thioglycolate Aqueous Solution, Aqueous Potassium Thioglycolate, Potassium Thioglycolate 40%, Potassium Thioglycolate 50%, Potassium Thioglycolate 60%, Potassium Thioglycolate 70%, Potassium Thioglycolate 80%, Potassium Thioglycolate Raw Material, Potassium Thioglycolate Cosmetic Raw Material, Potassium Thioglycolate Personal Care Ingredient, Potassium Thioglycolate Depilatory Ingredient, Potassium Thioglycolate Hair Care Ingredient, Potassium Thioglycolate Hair Treatment Ingredient, Potassium Thioglycolate Permanent Wave Ingredient, Potassium Thioglycolate Keratin Reducing Agent, Potassium Thioglycolate Sulfur Compound, Potassium Thioglycolate Organic Salt, Potassium Thioglycolate CAS 34452-51-2, Thioglycolic Acid Potassium Salt CAS 34452-51-2, Potassium Mercaptoacetate CAS 34452-51-2, Mercaptoacetic Acid Potassium Salt CAS 34452-51-2, Potassium Thioglycolate Commercial Grade, Commercial Potassium Thioglycolate, Potassium Thioglycolate Specialty Chemical, Potassium Thioglycolate Formulation Ingredient, Potassium Thioglycolate Processing Aid
APPLICATIONS
Potassium Thioglycolate is used in depilatory creams to weaken hair structure and support hair removal from the skin surface.
Potassium Thioglycolate is incorporated into alkaline depilatory systems where thioglycolate chemistry reduces keratin disulfide bonds.
Potassium Thioglycolate is used in cream, lotion, and gel depilatories where controlled pH and contact time are essential for performance and safety.
Potassium Thioglycolate is used in permanent wave formulations to reshape hair by reducing disulfide bonds in keratin.
Potassium Thioglycolate is incorporated into hair waving systems where hair structure is softened before oxidation or neutralization rebuilds disulfide linkages.
Potassium Thioglycolate is used in hair straightening and relaxing products in selected formulations where keratin reduction is required.
Potassium Thioglycolate is used in cosmetic formulations only under controlled regulatory limits and product-specific safety requirements.
Potassium Thioglycolate is incorporated into professional-use and consumer-use hair products depending on permitted concentration, pH, exposure time, and labeling rules.
Potassium Thioglycolate is used where strong reducing performance must be balanced with odor control, skin compatibility, and formula stability.
Potassium Thioglycolate is used in leather and textile processing as a reducing and modifying agent in selected systems.
Potassium Thioglycolate is incorporated into specialty processing baths where sulfur-based reduction chemistry supports fiber or substrate modification.
Potassium Thioglycolate is used in industrial formulations where thiol salt functionality and water compatibility are useful.
Potassium Thioglycolate is used as a chemical intermediate for producing thioglycolate derivatives and sulfur-containing compounds.
Potassium Thioglycolate is incorporated into specialty chemical synthesis where mercaptoacetate functionality is required.
Potassium Thioglycolate is valued because Potassium Thioglycolate provides water-compatible thioglycolate reducing activity for depilatory, hair-shaping, textile, leather, and specialty chemical applications.
Potassium Thioglycolate is used in hair removal cream formulations.
Potassium Thioglycolate helps break down keratin structure in unwanted hair.
Potassium Thioglycolate is used in depilatory products.
Potassium Thioglycolate supports effective removal of hair from the skin surface.
Potassium Thioglycolate is used in cosmetic depilatory lotions.
Potassium Thioglycolate helps soften and weaken hair fibers before wiping or rinsing.
Potassium Thioglycolate is used in professional hair removal products.
Potassium Thioglycolate supports controlled depilation when properly formulated.
Potassium Thioglycolate is used in alkaline hair removal systems.
Potassium Thioglycolate works effectively under high-pH conditions.
Potassium Thioglycolate is used in cream, gel, and lotion depilatory formats.
Potassium Thioglycolate helps create convenient topical hair removal products.
Potassium Thioglycolate is used in body hair removal formulations.
Potassium Thioglycolate supports removal of hair from legs, arms, and other suitable skin areas.
Potassium Thioglycolate is used in facial hair removal products where allowed and properly formulated.
Potassium Thioglycolate helps provide gentle-use depilatory systems when dosage and pH are controlled.
Potassium Thioglycolate is used in hair waving formulations.
Potassium Thioglycolate can reduce disulfide bonds in hair keratin.
Potassium Thioglycolate is used in permanent waving solutions.
Potassium Thioglycolate helps reshape hair structure during cosmetic hair treatment.
Potassium Thioglycolate is used in hair straightening formulations.
Potassium Thioglycolate supports temporary or semi-permanent reshaping of hair fibers.
Potassium Thioglycolate is used in salon chemical treatment products.
Potassium Thioglycolate helps modify hair texture through controlled reduction chemistry.
Potassium Thioglycolate is used in cosmetic formulation development.
Potassium Thioglycolate helps evaluate depilatory efficiency, odor control, and skin compatibility.
Potassium Thioglycolate is used in pH-adjusted personal care systems.
Potassium Thioglycolate supports formulations requiring thiol-based reducing activity.
Potassium Thioglycolate is used in leather processing.
Potassium Thioglycolate can help remove hair from hides in selected unhairing processes.
Potassium Thioglycolate is used in tanning auxiliary formulations.
Potassium Thioglycolate supports reduction and sulfhydryl chemistry in compatible leather systems.
Potassium Thioglycolate is used in textile processing research.
Potassium Thioglycolate may support fiber modification where reducing conditions are required.
Potassium Thioglycolate is used in wool treatment studies.
Potassium Thioglycolate can modify keratin-based fibers through disulfide bond reduction.
Potassium Thioglycolate is used in chemical synthesis.
Potassium Thioglycolate serves as a thioglycolate salt intermediate.
Potassium Thioglycolate is used in specialty organic reactions.
Potassium Thioglycolate introduces thiol-acetate functionality into selected chemical systems.
Potassium Thioglycolate is used in analytical chemistry.
Potassium Thioglycolate can act as a reducing agent in selected laboratory procedures.
Potassium Thioglycolate is used in metal treatment formulations.
Potassium Thioglycolate helps complex certain metal ions in compatible systems.
Potassium Thioglycolate is used in surface treatment research.
Potassium Thioglycolate supports studies involving sulfur-containing functional groups on metal surfaces.
Potassium Thioglycolate is used in polymer chemistry research.
Potassium Thioglycolate can participate in reactions requiring mercapto functionality.
Potassium Thioglycolate is used in cosmetic raw material manufacturing.
Potassium Thioglycolate supports production of thioglycolate-based personal care ingredients.
Potassium Thioglycolate is used in quality-control testing for depilatory products.
Potassium Thioglycolate helps assess active content and reducing strength in formulations.
Potassium Thioglycolate is used in applications requiring keratin reduction.
Potassium Thioglycolate supports depilatory, hair reshaping, leather, textile, and specialty chemical applications.
DESCRIPTION
Potassium Thioglycolate is the potassium salt of thioglycolic acid, and Potassium Thioglycolate contains both a thiol-derived mercaptoacetate group and an ionic potassium carboxylate group.
Potassium Thioglycolate acts as a reducing agent by breaking disulfide bonds in keratin, which explains its use in depilatory and hair-waving formulations.
Potassium Thioglycolate is typically used in alkaline formulations because higher pH increases thioglycolate reducing activity toward keratin structures.
Potassium Thioglycolate performance depends strongly on pH, and poor pH control can reduce effectiveness or increase irritation risk in cosmetic applications.
Potassium Thioglycolate can have a strong sulfur-like odor, so fragrance selection, packaging, and odor-management systems are important in finished products.
Potassium Thioglycolate can oxidize to disulfide species, and oxidation reduces reducing power and may affect product performance during storage.
Potassium Thioglycolate should be protected from strong oxidizers, acids, heavy metal contamination, and excessive heat because these factors can reduce stability or create hazardous reactions.
Potassium Thioglycolate should be stored in tightly closed containers to minimize air exposure, odor release, contamination, and active-content loss.
Potassium Thioglycolate should be used according to applicable cosmetic, industrial, occupational safety, transport, and environmental regulations for the target market and application.
Potassium Thioglycolate is the potassium salt of thioglycolic acid.
Potassium Thioglycolate is also known as potassium mercaptoacetate.
Potassium Thioglycolate is a sulfur-containing reducing agent.
Potassium Thioglycolate is widely used in cosmetic depilatory and hair treatment products.
Potassium Thioglycolate is typically supplied as an aqueous solution.
Potassium Thioglycolate may appear colorless to pale yellow depending on grade and concentration.
Potassium Thioglycolate has a characteristic sulfur-like odor.
Potassium Thioglycolate is soluble in water.
PROPERTIES
Chemical Formula: C2H3KO2S
Molecular Weight: 130.21 g/mol
Common Name: Potassium Thioglycolate
Chemical Type: Thioglycolate salt; reducing agent; depilatory active; keratin-modifying agent
Appearance: Clear colorless to pale yellow aqueous solution or white to off-white solid, grade dependent
Odor: Strong sulfur-like odor, grade dependent
Solubility: Soluble in water; limited compatibility with many nonpolar solvents
pH Behavior: Alkaline in many commercial aqueous solutions, grade dependent
Active Content: Grade dependent
Reducing Function: Reduces disulfide bonds in keratin and related substrates
Reactivity: Reacts with oxidizers, acids, metal ions, and disulfide-containing substrates
Stability: Stable under recommended storage; avoid oxidation, heat, air exposure, and contamination
Storage Temperature: 15–25°C, tightly closed, cool, dry or protected from evaporation depending on grade
Shelf Life: Typically 12–24 months in original sealed packaging, supplier dependent
FIRST AID
Inhalation:
Move to fresh air if vapors, mist, or sulfur odor is inhaled.
Seek medical attention if coughing, headache, dizziness, respiratory irritation, or breathing discomfort occurs.
Avoid further exposure until ventilation and handling controls are confirmed.
Skin Contact:
Remove contaminated clothing and rinse skin with plenty of water.
Wash thoroughly with soap and water after initial rinsing.
Seek medical advice if irritation, redness, burning, or allergic reaction develops.
Eye Contact:
Rinse cautiously with water for at least 15 minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek immediate medical attention because thioglycolate solutions can cause serious eye irritation or damage.
Ingestion:
Rinse mouth with water and do not induce vomiting.
Seek immediate medical attention or contact a poison center.
Never give anything by mouth to an unconscious person.
Note to Physicians:
Treat symptomatically.
Monitor for irritation, corrosive effects depending on pH, and systemic effects after significant thioglycolate exposure.
Provide supportive care as needed.
HANDLING AND STORAGE
Handling:
Use appropriate PPE including chemical-resistant gloves, safety goggles, protective clothing, and respiratory protection where exposure assessment requires it.
Avoid breathing vapors, mist, or aerosols and avoid skin and eye contact.
Use closed transfer or controlled dispensing where possible because Potassium Thioglycolate can have strong odor and irritating properties.
Ventilation:
Use local exhaust ventilation during transfer, mixing, neutralization, filling, and heated processing.
Avoid handling in confined spaces without adequate airflow.
Use ventilation systems designed to control sulfur odor, mist, and alkaline formulation exposure.
Storage:
Store in tightly closed containers in a cool, dry, well-ventilated area.
Protect from heat, air oxidation, moisture imbalance, evaporation, and contamination.
Keep away from strong oxidizers, strong acids, heavy metal salts, and incompatible reactive chemicals.
Spill and Leak Procedures:
Ventilate the area and restrict access to trained personnel.
Contain liquid spills with compatible inert absorbent or collect solid spills while avoiding dust generation.
Prevent entry into drains and dispose of waste according to local regulations and facility procedures.
Handling Precautions:
Control pH carefully because Potassium Thioglycolate performance and irritation potential depend strongly on alkaline formulation conditions.
Control oxidation because Potassium Thioglycolate can lose reducing activity when exposed to air, oxidizers, or metal contamination.
Rotate stock using FIFO practices to maintain consistent active content, odor profile, color, and reducing performance.
