PRODUCTS

PREVENTOL A 6

PREVENTOL A 6 = DIURON = 3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA

CAS Number: 330-54-1
EC Number: 206-354-4
MDL number: MFCD00018136
Molecular Formula : C9H10Cl2N2O

Chemical Composition
Diuron Tech 98.00
2, 3-Bis(3,4-dichlorophenyl)- dimethylguanidine 0.95
Dichloroaniline 0.16
Tris-(3,4- dichlorophenyl)-1,3,5-triazine-2,4,6-trione 0.50
azobenzene, azoxybenzene, monuron 0.20
1,3-Bis-(3,4-dichlorophenyl)-urea 0.19

Preventol A 6 is a urea derivative.
Preventol A 6 is a member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.
Preventol A 6 is (diuron) (for use in paint industry) - n'-(3,4 -dichlorophenyl)-n,n-dimethyl urea - broad spectrum algicide.

Preventol A 6 is a white crystalline solid.
Preventol A 6 is a wettable powder.
Preventol A 6 is Technical grade of diuron (urea-derivative).
Preventol A 6 is Broad spectrum algicide which is highly effective against algae found in the air and on masonry paints.
Preventol A 6 is a VOC-free dry-film preservative.

Preventol A 6 is an aqueous dispersion of approx. 50% diuron.
Preventol A 6 is a broad-spectrum algicide which is highly effective against algae found in the air and on masonry paints.
Preventol A 6 is designed for the manufacture of algicidal coatings and plasters for exterior applications.
Preventol A 6 is non-volatile, has low solubility in water and good toxicological properties.

These favourable properties, combined with the effectiveness of the product, make it ideal for use in the formulation of marine antifouling coatings used in seawater.
Preventol A 6 Provided the product is correctly stored and kept in the original sealed package, its shelf life is at least 2 years.
Preventol A 6 tends to form lumps.
This has no effect on Preventol A 6's quality.

Unlike organotin compounds, Preventol A 6 is light-stable.
Preventol A 6 has a role as a herbicide, a photosystem-II inhibitor, a xenobiotic, an environmental contaminant and a mitochondrial respiratory-chain inhibitor.
Preventol A 6 is a dichlorobenzene and a 3-(3,4-substituted-phenyl)-1,1-dimethylurea.
Preventol A 6 is a pre-emergent herbicide.

Preventol A 6 (CAS 330-54-1) is a substituted urea herbicide used for pre- and postemergent control on crop and noncrop areas, a mildewcide in paints, and an algicide in ponds and aquariums with very low estimated dietary, residential, and aggregate risks.
Preventol A 6 (CAS No.330-54-1) is a systemic herbicide, absorbed principally by the roots, with translocation acropetally in the xylem.
Preventol A 6 (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is an algicide and herbicide of the arylurea class that inhibits photosynthesis.

Preventol A 6 is a white, odorless, crystalline (sand-like) material which may be used in dilute solution.
Preventol A 6 is the trade name for DCMU, an algaecide and herbicide active ingredient used for controlling annual and perennial broadleaf and grassy weeds in agricultural settings as well as for industrial and commercial areas.
In its original form, Preventol A 6 is a white odorless solid and can come in many different formulations such as a wettable powder, granules, dry flowable products, pellets, suspended liquid concentrates, and water soluble mixtures.

Preventol A 6 is a phenyl urea herbicide.
Pre-emergent herbicide which may find Preventol A 6's way into aquatic environments, and consumable fruit/vegetation.
A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.

USES and APPLICATIONS of PREVENTOL A 6:
-Preventol A 6 is used Architectural coatings, Paints & Coatings Dry-Film Protection, Wood industry, and Wood preservatives
-Preventol A 6 is used algicidal active ingredient component in marine antifouling coatings.
-Preventol A 6 is a broad-spectrum algicide which is highly effective against both seawater and freshwater algae.
-For antifouling coatings Preventol A 6 is normally used in combination with copper compounds such as copper oxide and copper rhodanide to broaden the spectrum of activity against sessile sea animals like for example barnacles and tubeworms.
When incorporating and using Preventol A 6, care should be taken that Preventol A 6 is distributed homogeneously in the coating to ensure a reliable and uniform action.
-The concentration in marine antifouling coatings is usually between 2 and 8 %, calculated on the total formulation.
-Preventol A 6 is used for the formulation of algaecidal coatings and plasters for exterior applications and as an algaecidal active ingredient component in marine antifouling coatings.
-Preventol A 6 offers efficiency against seawater algae and those found in the air and on masonry paints.
-Preventol A 6 is used for the formulation of algicidal coatings and plasters for exterior applications.
-Preventol A 6 is used Algicidal active for the production of biocidal products.
-Preventol A 6 is used Modifier in epoxy resins.
-Preventol A 6 is used biocides safely.
-Preventol A 6 is used as a herbicide.
-Preventol A 6 is used at 10-30 kg/ha for total controlling of weeds and mosses on non-crop areas. Selective control of germinating grass and broad-leaved weeds in many crops, including asparagus, tree fruit, bush fruit, citrus fruit, vines, olives, pineapples, bananas, sugar cane, cotton, peppermint, alfalfa, forage legumes, cereals, maize, sorghum, and perennial grass-seed crops, at 0.6-4.8 kg/ha.
Phytotoxic residues in soil disappear within 1 season at these lower rates.
-Preventol A 6 applicable crops:
asparagus, tree fruit, bush fruit, citrus fruit, vines, olives, pineapples, bananas, sugarcane, cotton, peppermint, alfalfa, forage legumes, cereals, maize, sorghum, and perennial grass-seed crops
-Preventol A 6 (1,1-dimethyl, 3-(3’,4’-dichlorophenyl) urea) is a broad-spectrum residual herbicide and algaecide used in agriculture for pre-emergent and post-emergent control of broadleaved and grass weeds.
-Preventol A 6 is also used to control weeds and algae in and around water bodies and is a component of marine antifouling paints.
-Preventol A 6 is a herbicide and algaecide used in a variety of cropping and non-cropping situations
-Prior to some Preventol A 6 uses being suspended in late 2011 and the finalisation of the review in November 2012, diuron was used to:
*control weeds in agriculture—sugarcane, cotton, broadacre crops (oats, wheat, and barley) and some horticultural crops, including apples, pears, citrus, pineapples and bananas
*control weeds in irrigation channels, drainage ditches, around buildings, railway lines, sheds and driveways
*protect boats from marine algal growth (as a component of antifouling paints)
*prevent algal growth in home aquariums and ponds.
-The mode of action of Preventol A 6 is that it halts photosynthesis on treated plants, hindering the ability of the weed to turn light energy into chemical energy.
This is a crucial procedure needed for plant development and survival.
-Preventol A 6 is versatile in that it can be used as both a pre-emergent and post-emergent form of control on weeds and crops.
-Preventol A 6 has been best used in agricultural settings to control invasive weeds around forage crops, field crops, fruits, vegetables, nuts, and ornamental crops.
-In non agricultural settings, Preventol A 6 can be used on industrial sites, rights-of-way, around farm buildings, and on irrigation and drainage ditches.
-Preventol A 6 only works best when the active ingredient is applied to young weeds in their very early stage as a post-emergent or pre-emergently before the seeds have sprouted.
Preventol A 6 will not be effective against mature weeds.
-Preventol A 6 is an effective herbicide active ingredient that is used to treat invasive vegetation on both agricultural and non-agricultural sites.
-Preventol A 6 is also useful in removing mildew as well as a reliable killer of algae on commercial water bodies.
-Preventol A 6 is used as a herbicide (weed killer) in agriculture.

SYNTHESIS OF PREVENTOL A 6:
As described in the du Pont patent, the starting material is a substituted aryl amine, an aniline, which is treated with phosgene to form its isocyanate derivative.
This is subsequently reacted with dimethylamine to give the final product.
Aryl-NH2 + COCl2 → Aryl-NCO
Aryl-NCO + NH(CH3)2 → Aryl-NHCON(CH3)2

MECHANISM OF ACTION PREVENTOL A 6:
Preventol A 6 is a very specific and sensitive inhibitor of photosynthesis.
Preventol A 6 blocks the QB plastoquinone binding site of photosystem II, disallowing the electron flow from photosystem II to plastoquinone.
This interrupts the photosynthetic electron transport chain in photosynthesis and thus reduces the ability of the plant to turn light energy into chemical energy (ATP and reductant potential).
Preventol A 6 only blocks electron flow from photosystem II, Preventol A 6 has no effect on photosystem I or other reactions in photosynthesis, such as light absorption or carbon fixation in the Calvin cycle.

However, because Preventol A 6 blocks electrons produced from water oxidation in PS II from entering the plastoquinone pool, "linear" photosynthesis is effectively shut down, as there are no available electrons to exit the photosynthetic electron flow cycle for reduction of NADP+ to NADPH.
In fact, it was found that DCMU not only does not inhibit the cyclic photosynthetic pathway, but, under certain circumstances, actually stimulates it.
Because of these effects, Preventol A 6 is often used to study energy flow in photosynthesis.

PREVENTOL:
The PREVENTOL product line is a group of biocidal preparations under which we find both active substances and ready-made formulations that protect the final products against biological attack by bacteria, fungi or algae, thereby extending their lifespan and preserving their functionality.
In the field of paint and building materials production, PREVENTOL products are widely used in the following applications.
Protection or preservation of the finished product in packaging ( In Can ) and dry film protection ( Dry Film Protection ) of materials applied to mineral surfaces or wood.
Last but not least, we find the application of biocidal products also in the hygiene and disinfection of production ( Plant Hygiene ) and in the industrial or long-term protection of wood (Wood Protection ).
PREVENTOL BIT, BIT IT, D, DP, DBC, P is a combination of active substances BIT, CMIT/MIT, Bronopol, DBDCB, or others.

APPLICATION AND USE PREVENTOL:
*all water-based systems (paints, plasters, adhesives, sealants)
*hygiene of operation and production equipment
*disinfection of technological and rinsing water

PHYSICAL and CHEMICAL PROPERTIES of PREVENTOL A 6:
Molecular weight : 233,09 g/mol
Appearance Form: powder
Color: white
Odor: amine-like
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: 156 °C at 1.013 hPa
Initial boiling point and boiling range: 355 - 357 °C at 1.013,3 hPa
Flash point: No data available
Evaporation rate: No data available

Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: 1,45 at 19,9 °C
Water solubility: 0,029 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 2,84 at 20 °C
Autoignition temperature: >= 401 °C
Decomposition temperature: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: Not explosive
Oxidizing properties: The product has been shown not to be oxidizing.
Other safety information:
Surface tension 72,1 mN/m at 20 °C
Molecular Weight: 233.09
XLogP3: 2.7
Hydrogen Bond Donor Count: 1

Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 232.0170183
Monoisotopic Mass: 232.0170183
Topological Polar Surface Area: 32.3 Å²
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 211
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molar mass: 233.09 g·mol−1
Appearance: white crystalline solid
Density: 1.48 g/cm3
Melting point: 158 °C (316 °F; 431 K)
Boiling point: 180 °C (356 °F; 453 K)
Solubility in water: 42 mg/L
Vapor pressure: 0.000000002 mmHg (20°C)

FIRST AID MEASURES of PREVENTOL A 6:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of PREVENTOL A 6:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.

FIRE FIGHTING MEASURES of PREVENTOL A 6:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available

EXPOSURE CONTROLS/PERSONAL PROTECTION of PREVENTOL A 6:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.

HANDLING and STORAGE of PREVENTOL A 6:
-Precautions for safe handling:
*Hygiene measures:
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.

STABILITY and REACTIVITY of PREVENTOL A 6:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available

SYNONYMS:
Diuron
3-(3,4-Dichlorophenyl)-1,1-dimethylurea
Preventol A 6-D
diuron
3-(3,4-Dichlorophenyl)-1,1-dimethylurea
DCMU
Duran
Dynex
Dichlorfenidim
Herbatox
Vonduron
Dailon
Karmex
Marmer
Karmex DW
Di-on
Cekiuron
Crisuron
Lucenit
Unidron
1,1-Dimethyl-3-(3,4-dichlorophenyl)urea
Diuron Nortox
Karmex D
Karmex Diuron Herbicide
1-(3,4-Dichlorophenyl)-3,3-dimethylurea
N'-(3,4-Dichlorophenyl)-N,N-dimethylurea
Preventol A 6
Urox D
Diuron 4L
Direx 4L
DP Hardener 95
Telvar Diuron Weed Killer
Urea, N'-(3,4-dichlorophenyl)-N,N-dimethyl-
N-(3,4-Dichlorophenyl)-N',N'-dimethylurea
DCMU 99
HW 920
Karamex
N,N,-Dimethyl-N'-(3,4-dichlorophenyl)urea
Urea, 3-(3,4-dichlorophenyl)-1,1-dimethyl-
3-(3,4-Dichlor-phenyl)-1,1-dimethyl-harnstoff
1-(3,4-Dichlorophenyl)-3,3-dimethyluree
CHEBI:116509
9I3SDS92WY
3-(3,4-Dicloro-fenyl)-1,1-dimetil-urea
3-(3,4-Dichloor-fenyl)-1,1-dimethylureum
DTXSID0020446
NSC-8950
NCGC00094525-01
Anduron
Ansaron
Dirurol
Durashield
Herburon
Seduron
Bioron
Drexel
Farmco diuron
DSSTox_CID_446
3-(3,4-Dichloro-phenyl)-1,1-dimethyl-urea
Sup'r flo
DSSTox_RID_75595
DSSTox_GSID_20446
Diuron 900
Caswell No. 410
Ditox-800
Aguron
Diater
Diuron solution
USAF P-7
Diuron [ANSI:BSI:ISO]
USAF XR-42
Diuron [ISO]
CCRIS 1012
HSDB 382
Direx 80W
NSC 8950
AF 101
UNII-9I3SDS92WY
EPA Pesticide Chemical Code 035505
BRN 2215168
Xarmex
N-(3,4-Dichlorophenyl)-N,N-Dimethylurea
AI3-61438
Karmex DL
1-(3,4-Dichlorophenyl)-3,3-dimethyluree [French]
3-(3,4-Dichloor-fenyl)-1,1-dimethylureum [Dutch]
3-(3,4-Dicloro-fenyl)-1,1-dimetil-urea [Italian]
Karmex 80W
3-(3,4-Dichlor-phenyl)-1,1-dimethyl-harnstoff [German]
Spectrum_001823
1-(3,3-dimethylurea
3-(3,1-dimethylurea
SpecPlus_000424
N'-(3,N-dimethylurea
N-(3,N'-dimethylurea
1,4-dichlorophenyl)urea
3-(3,1-dimethylureum
DIURON [HSDB]
n,n-dimethyl-n'-(3,4-dichlorophenyl)urea
3-(3,1-dimetil-urea
Spectrum2_001229
Spectrum3_000822
Spectrum4_000662
Spectrum5_001956
DIURON [MI]
Diuron, >=98%
Cambridge id 5104305
SCHEMBL7279
3-(3,1-dimethyl-harnstoff
BSPBio_002343
KBioGR_001063
KBioSS_002328
SPECTRUM330030
MLS002207110
DivK1c_006520
SPBio_001078
CHEMBL278489
KBio1_001464
KBio2_002325
KBio2_004893
KBio2_007461
KBio3_001843
ZINC57287
NSC8950
WLN: GR BG DMVN1 & 1
Diuron 100 microg/mL in Methanol
HY-B0860
Tox21_111292
Tox21_201438
Tox21_301016
BDBM50487027
CCG-39151
Diuron 10 microg/mL in Acetonitrile
STK077954
AKOS001303464
Diuron 100 microg/mL in Acetonitrile
Tox21_111292_1
Urea,4-dichlorophenyl)-N,N-dimethyl-
Urea,4-dichlorophenyl)-1,1-dimethyl-
NCGC00094525-02
NCGC00094525-03
NCGC00094525-04
NCGC00094525-05
NCGC00094525-06
NCGC00094525-07
NCGC00094525-08
NCGC00094525-09
NCGC00254918-01
NCGC00258989-01
AS-15493
SMR000777941
Diuron, PESTANAL(R), analytical standard
3-(3,4-Dichlorophenol)-1,1-dimethylurea
DB-048327
CS-0012874
D1328
FT-0603378
FT-0667750
N,N-dimethyl-N'-(3,4-dichlorophenyl)-urea
N-(3,4-dichlorophenyl)-N',N'-dimethyl urea
C18428
A821585
Q425389
SR-01000195223
Diuron, certified reference material, TraceCERT(R)
J-018992
SR-01000195223-1
BRD-K75330923-001-02-6
Diuron solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard
W9M
N′-(3,4-Dichlorophenyl)-N,N-dimethylurea
3-(3,4-Dichlorophenyl)-1,1-dimethylurea
Karmex
Diuron
Direx
Urea, N'-(3,4-dichlorophenyl)-N,N-dimethyl-
Urea, 3-(3,4-dichlorophenyl)-1,1-dimethyl-
Duran
DCMU
DMU
Herbatox
Karmex
Karmex Diuron Herbicide
Karmex DW; Marmer
N-(3,4-Dichlorophenyl)-N',N'-dimethylurea
N'-(3,4-Dichlorophenyl)-N,N-dimethylurea
1-(3,4-Dichlorophenyl)-3,3-dimethylurea
1,1-Dimethyl-3-(3,4-dichlorophenyl)urea
3-(3,4-Dichlorophenyl)-1,1-dimethylurea
Dailon; Di-On; Dichlorfenidim
Dynex
HW 920
Karamex
Vonduron
3-(3,4-Dichloor-fenyl)-1,1-dimethylureum
3-(3,4-Dichlor-phenyl)-1,1-dimethyl-harnstoff
3-(3,4-Dichlorophenol)-1,1-dimethylurea
3-(3,4-Dicloro-fenyl)-1,1-dimetil-urea
Aguron
Cekiuron
Crisuron
Diater
Direx 4L
Direx 80W
Diuron 4L
Karmex 80W
Karmex DL
Unidron
Urox D
Xarmex
DCMU 99
DP Hardener 95
Diuron Nortox
Karmex D
N,N,-Dimethyl-N'-(3,4-dichlorophenyl)urea
Lucenit
Preventol A 6
N',N'-Dimethyl-N-(3,4-dichlorophenyl)urea
3-(3,4-Dichlorophenyl)-1,1-dimethylurea
1,1-Dimethyl-3-(3,4-dichlorophenyl)urea
1-(3,4-Dichlorophenyl)-3,3-dimethylurea
1-(3,4-Dichlorophenyl)-3,3-dimethyluree
3-(3,4-Dichloor-fenyl)-1,1-dimethylureum
3-(3,4-Dichlor-phenyl)-1,1-dimethyl-harnstoff
3-(3,4-Dichlorophenol)-1,1-dimethylurea
3-(3,4-dichlorophenyl)-1,1-dimethyl-urea
3-(3,4-Dicloro-fenyl)-1,1-dimetil-urea
Aguron
Anduron
Ansaron
Bioron
Cekiuron
Crisuron
Dailon
DCMU
DCMU 99
DI-ON
Di-On
Diater
Dichlorfenidim
Direx 4L
Direx 80W
Dirurol
Ditox-800
Diuron
Diuron 4L
Diuron 900
Diuron Nortox
DMU
DP Hardener 95
Drexel
DURAN
Duran
Durashield
DYNEX
Dynex
Farmco diuron
Herbatox
Herburon
Karamex
Karmex
Karmex 80W
Karmex D
Karmex Diuron Herbicide
Karmex DL
Karmex DW
Lucenit
M Velpar
Marmer
N'-(3,4-Dichlorophenyl)-N,N-dimethylurea
N,N,-Dimethyl-N'-(3,4-dichlorophenyl)urea
N-(3,4-Dichlorophenyl)-N',N'-dimethylurea
Preventol A 6
Seduron
SUP'R FLO
Telvar Diuron Weed Killer
Unidron
Urea, 3-(3,4-dichlorophenyl)-1,1-dimethyl-
Urox D
Vonduron
Xarmex
AF 101
HW 920
USAF P-7
USAF XR-42
AI3-61438
BRN 2215168
CASWELL NO. 410
CCRIS 1012
EINECS 206-354-4
EPA PESTICIDE CHEMICAL CODE 035505
HSDB 382
NSC 8950