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Synonyms: Decanoic acid, mixed diesters with octanoic acid and propylene glycol; Decanoic Acid, 1-Methyl-1,2-Ethanediyl Ester mixed with 1-Methyl-1,2-Ethanediyl Dioctanoate; Decanoic Acid, Mixed Diesters with Octanoic Acid and Propylene Glycol
Gel-textured ingredient used in many lightweight moisturizers. It’s a mix of propylene glycol and capric acid, a fatty acid derived from plants.
Synonyms:
Decanoic acid, mixed diesters with octanoic acid and propylene glycol; Decanoic Acid, 1-Methyl-1,2-Ethanediyl Ester mixed with 1-Methyl-1,2-Ethanediyl Dioctanoate; Decanoic Acid, Mixed Diesters with Octanoic Acid and Propylene Glycol ; Caprylic, Capric Acid, Propylene Glycol Diester; Propylene Glycol Dicaprate-Caprate; and Propylene Glycol, Caprylate Caprate Diester; Propylene glycol dicaprylate; 7384-98-7; 1,2-Propanediol dioctanoate; Propylene di(octanoate); Propane-1,2-diyl dioctanoate; Propylene glycol dioctanoate; 1-octanoyloxypropan-2-yl octanoate; Octanoic acid, 1,1'-(1-methyl-1,2-ethanediyl) ester; 1,2-Dicaprylin; Octanoic acid, 1-methyl-1,2-ethanediyl ester; 1,2-Propyleneglycol dioctanoate; PROPYLENEGLYCOLDIOCTANOATE; EINECS 230-962-9; Propyreneglycol dicaprylate; 1,2-Propanediyl dioctanoate; Propane-1,2-diyl dioctanoate 7384-98-7; Octanoic acid,1,1'-(1-methyl-1,2-ethanediyl) ester; cas 7384-98-7; PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE ; PROPYLENE GLYCOL DİCAPRYLATE/DİCAPRATE ; PROPYLENE GLYCOLDICAPRYLAT/DICAPRAT; PROPİLENE GLYCOL DICAPRYLATE/DICAPRATE ; PROPILENE GLYCOL DICAPRYLATE/DICAPRATE ; PROPİLEN GLYCOL DICAPRYLAT/DICAPRAT ; PROPILEN GLYCOL DICAPRYLAT/DICAPRAT; PROPYLENE GLYCOL DICAPRYLATE DICAPRATE ; PROPYLENE GLYCOL DİCAPRYLATE DİCAPRATE ; PROPYLENE GLYCOLDICAPRYLAT DICAPRAT; PROPİLENE GLYCOL DICAPRYLATE DICAPRATE ; PROPILENE GLYCOL DICAPRYLATE DICAPRATE ; PROPİLEN GLYCOL DICAPRYLAT DICAPRAT ; PROPILEN GLYCOL DICAPRYLAT DICAPRAT; Propilen Glikol Dikaprilat/Dikaprat; Propilen Glikol Dikaprilat Dikaprat; Propilene Glikol Dikaprilat/Dikaprat; Propilene Glikol Dikaprilat Dikaprat
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE
propylene glycol dicaprylate/dicaprate
Rating: GOOD
Categories: Uncategorized
Gel-textured ingredient used in many lightweight moisturizers. It’s a mix of propylene glycol and capric acid, a fatty acid derived from plants.
Propylene Glycol Dicaprylate/Dicaprate
Propylene Glycol Dicaprylate/Dicaprate is classified as :
Emollient
CAS Number of Propylene Glycol Dicaprylate/Dicaprate: 68583-51-7 / 58748-27-9 / 68988-72-7
EINECS/ELINCS No of Propylene Glycol Dicaprylate/Dicaprate: 271-516-3
COSING REF No of Propylene Glycol Dicaprylate/Dicaprate: 78795
Chem/IUPAC Name of Propylene Glycol Dicaprylate/Dicaprate: Decanoic acid, mixed diesters with octanoic acid and propylene glycol
Propylene Glycol Dicaprylate/Dicaprate
What Is Propylene Glycol Dicaprylate/Dicaprate?
Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate, Propylene Glycol Oleate and Propylene Glycol Oleate SE are monoesters of propylene glycol and fatty acids.
SE indicates that it is a self-emulsifying form that contains some sodium and/or potassium oleate. Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Dipelargonate, Propylene Glycol Oleate, Propylene Glycol Dicaprate, Propylene Glycol Diisostearate and Propylene Glycol Dilaurate are diesters of proplyene glycol and fatty acids. The use of the "/" in the name indicates that the ingredient is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate. In cosmetics and personal care products, Propylene Glycol monoesters and diesters are used in the formulation of moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks.
Why is Propylene Glycol Dicaprylate/Dicaprate used in cosmetics and personal care products?
The following functions have been reported for these ingredients.
Skin conditioning agent - emollient - Propylene Glycol Oleate, Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate
Skin conditioning agent - occlusive - Propylene Glycol Dicaprate, Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Diisostearate, Propylene Glycol Dilaurate, Propylene Glycol Dioleate, Propylene Glycol Dipelargonate
Surfactant - emulsifying agent - Propylene Glycol Oleate, Propylene Glycol Oleate SE, Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate
Viscosity increasing agent - nonaqueous - Propylene Glycol Dicaprate, Propylene Glycol Dicaprylate, Propylene Glycol Dicocoate, Propylene Glycol Diisostearate, Propylene Glycol Dilaurate, Propylene Glycol Dioleate, Propylene Glycol Dipelargonate
Scientific Facts:
Propylene glycol monoesters and diesters are typically produced from the reaction of propylene glycol with the corresponding fatty acid. For example, Propylene Glycol Oleate is produced via the reaction of propylene glycol with oleic acid.
Propylene Glycol Dicaprylate/Dicaprate
* A skin-conditioning agent
Propylene Glycol Dicaprylate/Dicaprate is derived from Propylene Glycol, and is a diester of proplyene glycol and fatty acids; it is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate (CosmeticsInfo.org). However, this compound differs greatly from Propylene Glycol, and is strictly a skin conditioning agent that utilizes its fatty acid components to maintain and improve lubrication and skin cell resilience, combining with proteins to promote healthy skin, according to research. Propylene Glycol Dicaprylate/Dicaprate is used in skin care and beauty products as an ingredient in moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks.
* A skin-conditioning agent
Functions of Propylene Glycol Dicaprylate/Dicaprate:
Propylene Glycol Dicaprylate/Dicaprate is derived from Propylene Glycol, and is a diester of proplyene glycol and fatty acids; it is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate (CosmeticsInfo.org). However, this compound differs greatly from Propylene Glycol, and is strictly a skin conditioning agent that utilizes its fatty acid components to maintain and improve lubrication and skin cell resilience, combining with proteins to promote healthy skin, according to research. Propylene Glycol Dicaprylate/Dicaprate is used in skin care and beauty products as an ingredient in moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks.
Propylene Glycol Dicaprylate/Dicaprate is FDA approved as a direct food additive, and CIR approved as well.
Safety Measures/Side Effects of Propylene Glycol Dicaprylate/Dicaprate:
According to the Cosmetics Database, Propylene Glycol Dicaprylate/Dicaprate is a moderate hazard ingredient. Skin irritation studies reviewed by the CIR Expert Panel found that Propylene Glycol Dicaprylate/Dicaprate caused minimal to no irritation, and negative comedogenicity results. "Data on the fatty acids and propylene glycol were negative for mutagenicity, chronic toxicity, and skin irritation and sensitizaiton"
However, Propylene Glycol Dicaprylate/Dicaprate is considered a penetration enhancer and may enhance the skin penetration of other chemicals. Users should exercise caution when using products and formulas that contain this ingredient when combined with other ingredients for which limits have been set based on low dermal absorption.
The Propylene Glycol Dicaprylate family of ingredients includes several esters and diesters of Propylene Glycol and fatty acids. These ingredients are used in cosmetic formulations as skin conditioning agents, viscosity increasing agents, and surfactants. Two skin irritation studies (minimal to no irritation) and a comedogenicity study (insignificant comedogen) on Propylene Glycol Dicaprylate/Dicaprate and a skin irritation study (slight) and an acute oral toxicity study (nontoxic) on Propylene Glycol Laurate were available. Available data were also found indicating that Propylene Glycol Dicaprylate/Dicaprate and Propylene Glycol Dipelargonate may enhance the skin penetration of other chemicals. Because of the ability of these Polyethylene Glycol esters and diesters to enhance penetration of other agents, it was recommended that care be taken in using these and other Polyethylene Glycol esters and diesters in cosmetic products. Previous Cosmetic Ingredient Review safety assessments of related ingredients, including Polyethylene Glycol, Polyethylene Glycol Stearate, Coconut Oils and Acids, Isostearic Acid, Lauric Acid, Myristic Acid, Oleic Acid, and Caprylic/Capric Triglyceride, were summarized. Included were mutagenicity, chronic toxicity, and skin irritation and sensitization data. Based in part on the limited data available on the ingredients included in the report, but more so on the previous reviews of chemically similar moieties, it was concluded that Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Dipelargonate, Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate, Propylene Glycol Oleate, Propylene Glycol Oleate SE, Propylene Glycol Dioleate, Propylene Glycol Dicaprate, Propylene Glycol Diisostearate, and Propylene Glycol Dilaurate are safe.
Propylene Glycol Dicaprylate/Dicaprate Propylene Glycol Dicaprylate/Dicaprate (CAS Nos. 58748- 27-9 ; 9062-04-8; and 68988-72-7) is a mixture of the propylene glycol diesters of caprylic and capric acids The structures of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate appear on the preceding page. Propylene Glycol Dicaprylate/Dicaprate is also defined as the propylene glycol diester of short chain, predominantly naturally derived C8-Clo fatty acids . It is soluble in alcohol containing up to 20% water and its viscosity is usually low . Other names for this mixture include: Decanoic Acid, 1-Methyl-1,2-Ethanediyl Ester mixed with 1-Methyl-1,2-Ethanediyl Dioctanoate; Decanoic Acid, Mixed Diesters with Octanoic Acid and Propylene Glycol ; Caprylic, Capric Acid, Propylene Glycol Diester; Propylene Glycol Dicaprate-Caprate; and Propylene Glycol, Caprylate Caprate Dieste Propylene Glycol Dicaprylate/Dicaprate has also been defined as the propylene glycol diester of saturated vegetable acids (C8-ClO chain length) that contains 65 to 80% caprylic acid and 15 to 30% capric acid
Details
Propylene Glycol Dicaprylate/Dicaprate is an emollient that leaves a light, non-oily smooth and velvet skin sensation. According to manufacturer info it's also great at dispersing and dissolving pigments and sunscreen actives. Most often you will meet this guy in light moisturizers, sunscreens or makeup products.
Properties
Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards P - R Less...
grade pharmaceutical primary standard
mfr. no. USP
Featured Industry Pharmaceutical (small molecule)
InChI 1S/C10H20O2.C8H16O2.C3H8O2/c1-2-3-4-5-6-7-8-9-10(11)12;1-2-3-4-5-6-7-8(9)10;1-3(5)2-4/h2-9H2,1H3,(H,11,12);2-7H2,1H3,(H,9,10);3-5H,2H2,1H3
InChI key YZWQUQVFVLJWCS-UHFFFAOYSA-N
Description
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Analysis Note
Propylene Glycol Dicaprylate/Dicaprate are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Molecular Weight of Propylene Glycol Dicaprylate/Dicaprate: 328.5 g/mol
XLogP3-AA of Propylene Glycol Dicaprylate/Dicaprate: 6.4
Hydrogen Bond Donor Count of Propylene Glycol Dicaprylate/Dicaprate: 0
Hydrogen Bond Acceptor Count of Propylene Glycol Dicaprylate/Dicaprate: 4
Rotatable Bond Count of Propylene Glycol Dicaprylate/Dicaprate: 17
Exact Mass of Propylene Glycol Dicaprylate/Dicaprate: 328.26136 g/mol
Monoisotopic Mass of Propylene Glycol Dicaprylate/Dicaprate: 328.26136 g/mol
Topological Polar Surface Area of Propylene Glycol Dicaprylate/Dicaprate: 52.6 Ų
Heavy Atom Count of Propylene Glycol Dicaprylate/Dicaprate:23
Formal Charge of Propylene Glycol Dicaprylate/Dicaprate: 0
Complexity of Propylene Glycol Dicaprylate/Dicaprate: 302
Isotope Atom Count of Propylene Glycol Dicaprylate/Dicaprate: 0
Defined Atom Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 0
Undefined Atom Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 1
Defined Bond Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 0
Undefined Bond Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 0
Covalently-Bonded Unit Count of Propylene Glycol Dicaprylate/Dicaprate: 1
Compound of Propylene Glycol Dicaprylate/Dicaprate Is Canonicalized : Yes
