PROPYLENE GLYCOL METHYL ETHER ACETATE

Propylene Glycol Methyl Ether Acetate

CAS Number:    108-65-6
European Community (EC) Number: 203-603-9

Molecular Formula: C6H12O3 or CH3CH(OCOCH3)CH2OCH3

Propylene glycol methyl ether acetate (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, and cleaners. 

In the semiconductor industry, PGMEA is a commonly used solvent, primarily for the application of surface adherents such as Bis(trimethylsilyl)amine (HMDS) on silicon wafers. 
The compound is often the most abundant airborne, molecular contamination (AMC) in semiconductor cleanrooms, due to its evaporation into ambient air.

Propylene glycol methyl ether acetate is a colorless liquid with a sweet ether-like odor.

Propylene glycol monomethyl ether acetate has been used in the development of fluidic channels to be incorporated in a poly(dimethylsiloxane) (PDMS)-based microfluidic device.

Propylene Glycol Mono Methyl Ether Acetate (PMAc) is a clear, colorless liquid ester. 
PMAc is used in an industrial setting as a solvent for automotive paints and industrial coatings, as a solvent in the electronics industry and in silk screen inks. 
PMAc is found in household cleaners, paints, spray paints, lacquers, varnishes and pesticides. 
PMAC is very efficient at dissolving resins used in paints, inks, lacquers, and other types of surface coatings.

PM Acetate (Propylene Glycol Monomethyl Ether Acetate) is a slow evaporating solvent with both ether and ester functional groups. 
Propylene Glycol Methyl Ether Acetate is a colorless liquid with a mild odor. 
PM Acetate is an excellent solvent for many commonly used coating polymers, including cellulose acetate butyrate, nitrocellulose, epoxy resins, acrylic copolymers, and phenoxy resins. 
The combination of slow evaporation rate and good solvent activity makes PM acetate an effective retarder solvent for use in lacquers, thinners, and baking enamels. 
Propylene Glycol Methyl Ether Acetate is supplied as a urethane grade solvent.

PGME and PGMEA are both glycol ethers based on propylene oxide and methanol. 
They are solvents having a bi-functional nature (ether-alcohol and the respective acetate). 
They are both clear liquids, with PGMEA having a pleasant, fruity odour. 

They are used as intermediates and in formulations in industrial, professional or consumer applications, mainly in surface coatings, printing inks, cleaners, agrochemical or de-icing/anti-icing formulations. 
They are also used as extractants, as coalescing agents and as flow improvers in waterbased paints. 

Propylene Glycol Methyl Ether Acetate is a glycol type solvent used in inks, coatings, and cleaners. 
Ungraded products are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.

Methoxy propyl acetate, also known as propylene glycol monomethyl ether acetate, is a clear, colourless liquid with a mild ether-like odour. 
Propylene Glycol Methyl Ether Acetate is only slightly soluble in water but miscible with most common organic solvents. 
Methoxy propyl acetate is slightly hygroscopic, relatively fast evaporating and has a low viscosity. 
Propylene Glycol Methyl Ether Acetate enters into reactions which are characteristic of both esters and ethers, displaying their good solvent power.

Methoxy propyl acetate is produced by reacting propylene oxide with methanol using a catalyst.

Often used in coatings, inks and cleaners.

Applications of Methoxy Propyl Acetate (Propylene Glycol Monomethyl Ether Acetate):
The main applications of methoxy propyl acetate are in coatings and printing inks, where it is frequently used as an alternative to ethoxyethyl acetate. 
Propylene Glycol Methyl Ether Acetate is used as a carrier solvent for resins and inks that are incompatible with water such as acrylics, epoxies, alkyds and polyesters.

Methoxy propyl acetate is formulated into a great many other industrial and commercial products such as paints, lacquers, varnishes, cleaners, ink removers, pesticides, adhesives, dyes for furniture polishes, wood stains, leather and textiles, and also as a binder for core sands in foundries.

Methoxy Propyl Acetate (also known as PMA, 1-methoxy-2-acetoxypropane, or propylene glycol monomethyl ether-1,2-acetate) is a clear liquid that has limited miscibility with water. 
Propylene Glycol Methyl Ether Acetate is a medium volatility solvent with a mild odour and has the formula C6H12O3.

 
Propylene Glycol Methyl Ether Acetate can be used as a solvent. 
Propylene Glycol Methyl Ether Acetate provides strong dissolving ability to the non-polar and polar substances. 
Propylene Glycol Monomethyl Ether Acetate(PMA) is used in the production of inks, paints, textile dyes and textile oils. 
Propylene Glycol Methyl Ether Acetate is recommended for car, TV, refrigerator, and aircraft paint.

Propylene glycol monomethyl ether acetate (PGMEA) is a photoresist solvent. 
Its degradation by microorganisms in different soil types has been investigated. 
An oral reference dose (RfD) value of PGMEA has been obtained from inhalation studies. 
The solubility of (5-alkylsulfonyloxyimino-5H-thiophen-2-ylidene)-2-methylphenyl-acetonitriles in PGMEA has been analyzed.

Propylene glycol monomethyl ether acetate has been used in the development of fluidic channels to be incorporated in a poly(dimethylsiloxane) (PDMS)-based microfluidic device.

Propylene Glycol Methyl Ether Acetate (PMA/PGMA) is a colorless liquid with a aromatic, fruity odor that is used as an excellent industrial solvent with low toxicity and has strong solubility for polar and unpolar materials, which can be used for advanced paints, printing inks as well as some other polymers including glycol acid resin, acrylic acid resin, epoxy resin and nitrocellulose.

Propylene glycol methyl ether acetate is a moderate evaporating, hydrophobic glycol ether with low viscosity and excellent properties for solvent-borne systems.

Propylene glycol methyl ether, also known as 1-methoxy-2-propanol, is a colorless organic chemical compound. 
Generally, Propylene glycol methyl ether is medium boiling glycol ether that is categorized under P-series glycol ether group. 
Propylene Glycol Methyl Ether is produced by the reaction between propylene oxide and methanol which is carried out in presence catalyst. 
Propylene glycol methyl ether are used prevalently as an organic solvent in commercial as well as industrial applications such as printing ink, chemical, agricultural, and automotive, among others.

The physico-chemical properties of Propylene glycol methyl ether such as excellent solvent activity, high dilution ratio, medium evaporation rate, and readily biodegradable nature, among other owing to which it appears as suitable alternative for petroleum based solvents. 
Thereby, it leads to increase in demand for Propylene glycol methyl ether in several industries such as chemical, automotive and paint & coating is increased in order to support sustainability development

Propylene glycol methyl ether acetate (PMA) & propionate (PMP) is a low-toxic high-level solvent, which has both ether and carbonyl groups in its molecule, and the carbonyl group forms a lipid structure and contains alkyl groups. 
There are both non-polar and polar parts in the same molecule. 
The functional groups of these two parts restrict and repel each other, and each plays its inherent role. 
Therefore, it has a certain solubility to non-polar and polar substances. Widely used in high-end coatings, resins, ink printing, electronic chemicals, etc.

Propylene Glycol Methyl Ether Acetate is a glycol type solvent used in inks, coatings, and cleaners.

Propylene glycol methyl ether acetate (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, and cleaners.

In the semiconductor industry, PGMEA is a commonly used solvent, primarily for the application of surface adherents such as Bis(trimethylsilyl)amine (HMDS) on silicon wafers. 
The compound is often the most abundant airborne, molecular contamination (AMC) in semiconductor cleanrooms, due to its evaporation into ambient air.

Examples of use
-Solvent for Coatings
-Inks
-Pharmaceuticals/Agrochemicals
-Polymeric materials
-Adhesives
-and Electronic materials
-Plasticizers 
-Surfactants
-Lubricants 
-Detergents

Key attributes
-Excellent solvent activity
-Non-HAP
-Non-SARA
-Readily biodegradable
-Slow evaporation rate
-Urethane grade

Applications:
-Aerospace coatings
-Architectural coatings
-Auto OEM
-Auto plastics
-Auto refinish
-Automotive parts & accessories
-Commerical printing inks
-Furniture
-General industrial coatings
-Industrial cleaners
-Industrial maintenance
-Janitorial & household cleaners
-Marine
-Molding & trim interior
-Packaging inks non food contact
-Process solvents
-Protective coatings
-Road markings
-Solvents/stripping agents
-Truck/bus/RV
-Wood coatings

Typical Physical Properties

Molecular Weight: 132.16 g/mol
Empirical Formula: C6H12O3
Appearance: Colorless Liquid
Freezing Point: -66°C (-87°F)
Flash Point – Closed Cup: 42°C (108°F)
Boiling Point at 760mmHg: 146°C (295°F)
Autoignition Temperature: 333°C
Density at 20°C: 0.967 kg/l
8.07 lb/gal
Vapor Pressure at 20°C: 2.8 mmHg
Evaporation Rate (nBuAc = 1): 0.33
Solubility at 20°C
(in Water): 16%
(Water in): 3%
Refractive Index at 25°C: 1.40
Viscosity at 25°C: 0.8 cP
Surface Tension at 25°C: 26.9 dynes/cm
Lower Flammability in Air: 1.5% v/v
Upper Flammability in Air: 7.0% v/v
Specific Heat at 25°C: 1.85 J/g/°C
Heat of Vaporization at normal boiling point: 296 J/g
Heat of Combustion at 25°C: 23.8 kJ/g

Storage and Handling
General industry practice is to store PMAc in carbon steel vessels. 
Storage in properly lined steel or stainless steel to avoid slight discoloration from carbon steel is recommended.
Product stored or delivered in unlined carbon steel vessels must be filtered due to technically unavoidable particles.
PMAc should be stored under a nitrogen blanket when available. 
Avoid contact with air when storing for long periods of time. 
This product may absorb water if exposed to air.
PMAc should be stored only in tightly closed, properly vented containers away from heat, sparks, open flame or strong oxidizing agents. 
Use only non-sparking tools. 
Containers should be grounded before beginning transfer. 
Electrical equipment should conform to national electric code. 
Handle empty containers carefully. 
Flammable combustible residue remains after emptying.
Provided proper storage and handling precautions are taken, PMAc is stable for at least 12 months from the date of manufacture. 
PMAc that is subsequently repackaged, handled and/or delivered by third parties may have a different shelf life and may require third party shelf life studies. 
Product past the retest date should be evaluated to confirm that all specifications are within their limits before use. 

SYNONYMS:

methoxypropyl acetate

PGMEA cpd

propylene glycol methyl ether acetate

1-Methoxy-2-propyl acetate

108-65-6

1-methoxypropan-2-yl acetate

PGMEA

Propylene glycol methyl ether acetate

Propylene glycol monomethyl ether acetate

2-Acetoxy-1-methoxypropane

1-Methoxy-2-acetoxypropane

2-Methoxy-1-methylethyl acetate

2-Propanol, 1-methoxy-, acetate

METHOXYISOPROPYL ACETATE

Propyleneglycol monomethyl ether acetate

NSC 2207

1-METHOXY-2-PROPANOL ACETATE

Acetic acid, 2-methoxy-1-methylethyl ester

EINECS 203-603-9

2-Propanol, 1-methoxy-, 2-acetate

PROPYLENEGLYCOLMETHYLETHERACETATE

2-(1-Methoxy)propyl acetate

MFCD00038500

1,2-Propanediol monomethyl ether acetate

Propylene glycol 1-methyl ether 2-acetate

Dowanol (R) PMA glycol ether acetate

BRN 1751656

AI3-18548

Arcosolv PMA

Dowanol PMA

2-Propanol, acetate

Ektasolve PM Acetate

propylene glycol monomethylether acetate

DSSTox_CID_6796

EC 203-603-9

Propylene Glycol 1-Monomethyl Ether 2-Acetate

DSSTox_RID_78216

1-methoxy-2-acetoxy propane

DSSTox_GSID_26796

SCHEMBL15667

CHEMBL3182130

DTXSID1026796

HSDB 8443

LLHKCFNBLRBOGN-UHFFFAOYSA-

NSC2207

NSC-2207

propyleneglycol methyl ether acetate

Tox21_201436

AKOS015837930

Glycol Ether PM Acetate Reagent Grade

NCGC00249046-01

NCGC00258987-01

CAS-108-65-6

FT-0675939

P1171

X6007

1,2-Propanediol 1-Monomethyl Ether 2-Acetate

1,2-Propanediol monomethyl ether acetate, 99%

Propylene glycol monomethyl ether acetate(PMA)

Propylene glycol monomethyl ether acetate, 99%

J-504836

Q2170375

Propylene glycol monomethyl ether acetate, >=99.0% (GC)

Propylene glycol monomethyl ether acetate, ReagentPlus(R), >=99.5%

Propylene glycol monomethyl ether acetate, Vetec(TM) reagent grade

Propylene glycol 1-methyl ether 2-acetate 100 microg/mL in Acetonitrile