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Propylene Glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste.
Propylene Glycol's chemical formula is CH3CH(OH)CH2OH.
Containing two alcohol groups, E 1520 (MONO PROPYLEN GLYCOL) is classed as a diol.
CAS Number: 57-55-6
EC Number: 200-338-0
IUPAC Name: Propane-1,2-diol
Chemical Formula: C3H8O2
Other names: 1,2-propanediol, 57-55-6, propane-1,2-diol, 1,2-Propylene glycol, 1,2-dihydroxypropane, 2-Hydroxypropanol, Isopropylene glycol, Methylethyl glycol, Methylethylene glycol, Monopropylene glycol, Dowfrost, Sirlene, Trimethyl glycol, 2,3-Propanediol, Propylene Glycol USP, Solargard P, alpha-Propyleneglycol, Solar Winter BAN, dl-Propylene glycol, DL-1,2-Propanediol, Ucar 35, 1,2-Propylenglykol, (RS)-1,2-Propanediol, Sentry Propylene Glycol, PG 12, FEMA No. 2940, (+-)-1,2-Propanediol, Kilfrost ABC-S, (+-)-Propylene glycol, Caswell No. 713, General lube, Kollisolv pg, CCRIS 5929, HSDB 174, 1,2 Propanediol, All purpose lubricant, AI3-01898, alpha-Propylene glycol, 1,2-Propylenglykol [German], NSC 69860, HOCH2CH(OH)Me, MeCH(OH)CH2OH, EPA Pesticide Chemical Code 068603, CHEBI:16997, Propyleneglycolum, .alpha.-Propylene glycol, CH3CH(OH)CH2OH, HOCH2CH(OH)CH3, 1,2-(RS)-Propanediol, propylene glycerol, Propylene glycol (solvent), 1,2-propandiol, EINECS 200-338-0, (+/-)-1,2-propanediol, 1000PG, MFCD00064272, NSC-69860, SDM No. 27, 1,2-propane-diol, Ins-1520, UNII-6DC9Q167V3, BRN 1340498, DTXSID0021206, PROPANEDIOL-, 6DC9Q167V3, Propylene glycol dl-form, S-(+)-Propylene glycol, Ins no.1520, 123120-98-9, propylenglycol, Propylene glycol [USP:JAN], DTXCID901206, 1,2-Propanediol (8CI,9CI), ( inverted exclamation markA)-1,2-Propanediol, 1,2-PDO, E-1520, EC 200-338-0, (2RS)-PROPANE-1,2-DIOL, NSC69860, L-1,2-propanediol, Poly(propylene glycol) average Mn 400, NCGC00090739-02, Poly(propylene glycol) average Mn 2000, Poly(propylene glycol) average Mn 4000, Prolugen, Propylene glycol (USP:JAN), PROPYLENE GLYCOL (II), PROPYLENE GLYCOL [II], propylene-glycol, C3H8O2, Propan-1,2-Diol, Ilexan P, PROPYLENE GLYCOL (MART.), PROPYLENE GLYCOL [MART.], PROPYLENE GLYCOL (USP-RS), PROPYLENE GLYCOL [USP-RS], 1,2-(RS)-Propanediol; 1,2-Dihydroxypropane; 1,2-Propylene glycol, PROPYLENE GLYCOL (EP MONOGRAPH), PROPYLENE GLYCOL [EP MONOGRAPH], Glycol, Propylene, CAS-57-55-6, PROPYLENE GLYCOL (USP MONOGRAPH), PROPYLENE GLYCOL [USP MONOGRAPH], 63625-56-9, GLYCEROL IMPURITY C (EP IMPURITY), GLYCEROL IMPURITY C [EP IMPURITY], 1,2-propane diol, ()-1,2-propanediol, (S)-(+)-Propylene glycerol, Propilenoglicol, Propylenglykol, Propylenglycolum, Systane Balance, Metiletilenglicol, Propyleeniglykoli, Vet Lube, Glicol propilenico, Glikol propylenowy, 1-2-propanediol, 1.2-propanediol, OB Lube, 2-Dihydroxypropanol, Propylene glycol; (RS)-propane-1,2-diol; Glycerol Imp. C (EP); GR 43314X; Glycerol Impurity C, Systane COMPLETE, 1,2 -propanediol, Lubiseptol Lubricant, 1,2-Hydroxypropane, 1,2-propyleneglycol, Propylene Glycol (Propane-1,2-diol), Propane-1,2-glycol, LS-1391, DEROFEN MIEL, Sirlene /Former use/, KETO-TREAT, Propylene glycol, USP, Sterile Lubricant drops, Systane COMPLETE PF, Propylene glycol (TN), racemic propylene glycol, racemic 1,2-propanediol, DSSTox_CID_1206, Walgreen Sterile Lubricant, Propylene Glycol U.S.P., bmse000302, Epitope ID:161748, GENERAL OB LUBRICANT, propylene glycol cefatrizine, CVS Health Lubricant Drops, 1,2-Propanediol 100 microg/mL in Acetonitrile, DSSTox_RID_78594, Propylene glycol, FCC, FG, DSSTox_GSID_27863, 3-01-00-02142 (Beilstein Handbook Reference), MLS001055394, PROPYLENE GLYCOL [MI], WLN: QY1&1Q, Eyelash and Eyebrow Lengthener, PROPYLENE GLYCOL [FCC], PROPYLENE GLYCOL [JAN], CHEMBL286398, GR12, Propylene glycol (JP18/USP), 1,2-Propanediol, ACS reagent, CVS Lubricant Eye Drops 15mL, PROPYLENE GLYCOL [FHFI], PROPYLENE GLYCOL [HSDB], PROPYLENE GLYCOL [VANDF], (.+/-.)-1,2-Propanediol, PROPYLENE GLYCOL [WHO-DD], PROPYLENE GLYCOL [WHO-IP], HMS3039O11, 1,2-Propanediol, LR, >=99%, BCP23677, HY-Y0921, NSC35747, NSC35748, NSC35749, Tox21_111003, Tox21_201812, Tox21_300006, Tox21_301441, 1,2-Propanediol, USP, 99.5%, BBL011472, MSK000649, NSC-35747, NSC-35748, NSC-35749, STL146584, 1,2-Propanediol, analytical standard, Equate Support Moisture Lubricant Eye, 1,2-Propanediol, puriss., 99.5%, AKOS000121049, AKOS016355793, Poly(propylene glycol) - M.W=4000, PROPYLENE GLYCOL DL-FORM [MI], Walgreens Complete Lubricant Eye Drops, DB01839, FP35394, SB44656, SB44657, PROPYLENEGLYCOLUM [WHO-IP LATIN], Restorative Formula Lubricant Eye Drops, USEPA/OPP Pesticide Code: 068603, NCGC00090739-01, NCGC00090739-03, NCGC00090739-04, NCGC00254159-01, NCGC00255183-01, NCGC00259361-01, 1,2-Propanediol, ReagentPlus(R), 99%, BP-21014, DA-66939, E490, FP177015, HEB Lubricant Eye Drops Dry Eye Therapy, Non Spermicidal Sterile Lubricating Jelly, SMR000677948, SY003769, SY003770, CAS-25322-69-4, DB-013280, Lubricant Eye Drops Restorative Performance, PROPYLENE GLYCOL (SOLVENT) [VANDF], 1,2-Propanediol, ACS reagent, >=99.5%, 1,2-Propanediol, ReagentPlus(R), >=99%, CS-0015917, E1520, NS00009085, P0485, S6258, EN300-21726, 1,2-Propanediol, analytical reference material, 200-338-0, 613-293-0
Propylene Glycol is miscible with a broad range of solvents, including water, acetone, and chloroform.
In general, glycols are non-irritating and have very low volatility.
Propylene Glycol is produced on a large scale primarily for the production of polymers.
In the European Union, E 1520 (MONO PROPYLEN GLYCOL) has E-number E1520 for food applications.
For cosmetics and pharmacology, the number is E490.
Propylene Glycol is also present in propylene glycol alginate, which is known as E405.
Propylene Glycol is a compound which is GRAS (generally recognized as safe) by the US Food and Drug Administration under 21 CFR x184.1666, and is also approved by the FDA for certain uses as an indirect food additive.
Propylene Glycol is approved and used as a vehicle for topical, oral, and some intravenous pharmaceutical preparations in the U.S. and in Europe.
Structure of Propylene Glycol
Propylene Glycol is sometimes called (alpha) α-propylene glycol to distinguish it from the isomer propane-1,3-diol, known as (beta) β-propylene glycol.
Propylene Glycol is chiral.
Commercial processes typically use the racemate.
The S-isomer is produced by biotechnological routes.
Production of Propylene Glycol
Industrial
Industrially, Propylene Glycol is mainly produced from propylene oxide (for food-grade use).
According to a 2018 source, 2.16 M tonnes are produced annually.
Manufacturers use either non-catalytic high-temperature process at 200 °C (392 °F) to 220 °C (428 °F), or a catalytic method, which proceeds at 150 °C (302 °F) to 180 °C (356 °F) in the presence of ion exchange resin or a small amount of sulfuric acid or alkali.
Final products contain 20% propylene glycol, 1.5% of dipropylene glycol, and small amounts of other polypropylene glycols.
Further purification produces finished industrial grade or USP/JP/EP/BP grade propylene glycol that is typically 99.5% or greater.
Use of USP (US Pharmacopoeia) propylene glycol can reduce the risk of Abbreviated New Drug Application (ANDA) rejection.
Propylene Glycol can also be obtained from glycerol, a byproduct from the production of biodiesel.
This starting material is usually reserved for industrial use because of the noticeable odor and taste that accompanies the final product.
Laboratory of Propylene Glycol
S-Propanediol is synthesized via fermentation methods.
Lactic acid and lactaldehyde are common intermediates.
Dihydroxyacetone phosphate, one of the two products of breakdown (glycolysis) of fructose 1,6-bisphosphate, is a precursor to methylglyoxal.
This conversion is the basis of a potential biotechnological route to the commodity chemical 1,2-propanediol.
Three-carbon deoxysugars are also precursor to the 1,2-diol.
Applications of Propylene Glycol
Polymers
Forty-five percent of Propylene Glycol produced is used as a chemical feedstock for the production of unsaturated polyester resins.
In this regard, Propylene Glycol reacts with a mixture of unsaturated maleic anhydride and isophthalic acid to give a copolymer.
This partially unsaturated polymer undergoes further crosslinking to yield thermoset plastics.
Related to this application, Propylene Glycol reacts with propylene oxide to give oligomers and polymers that are used to produce polyurethanes.
Propylene Glycol is used in water-based acrylic architectural paints to extend dry time which it accomplishes by preventing the surface from drying due to its slower evaporation rate compared to water.
Food and drug
Propylene Glycol is also used in various edible items such as coffee-based drinks, liquid sweeteners, ice cream, whipped dairy products and soda.
Vaporizers used for delivery of pharmaceuticals or personal-care products often include Propylene Glycol among the ingredients.
In alcohol-based hand sanitizers, Propylene Glycol is used as a humectant to prevent the skin from drying.
Propylene Glycol is used as a solvent in many pharmaceuticals, including oral, injectable, and topical formulations.
Many pharmaceutical drugs which are insoluble in water utilize propylene glycol as a solvent and carrier; benzodiazepine tablets are one example.
Propylene Glycol is also used as a solvent and carrier for many pharmaceutical capsule preparations.
Additionally, certain formulations of artificial tears use Propylene Glycol as an ingredient.
Antifreeze
The freezing point of water is depressed when mixed with Propylene Glycol.
Propylene Glycol is used as aircraft de-icing and anti-icing fluid.
A 50% water-diluted and heated solution is used for removal of icing accretions from the fuselages of commercial aircraft on the ground (de-icing), and 100% undiluted cold solution is used only on wings and tail surfaces of an aircraft in order to prevent ice accretion from forming during a specific period of time before takeoff (anti-icing).
Normally, such time-frame is limited to 15–90 minutes, depending on the severity of snowfall and outside air temperature.
Water-Propylene Glycol mixtures dyed pink to indicate the mixture is relatively nontoxic are sold under the name of RV or marine antifreeze.
Propylene Glycol is frequently used as a substitute for ethylene glycol in low toxicity, environmentally friendly automotive antifreeze.
Propylene Glycol is also used to winterize the plumbing systems in vacant structures.
The eutectic composition/temperature is 60:40 propylene glycol:water/−60 °C.
The −50 °F/−45 °C commercial product is, however, water rich; a typical formulation is 40:60.
Electronic cigarettes liquid
Propylene Glycol, glycerin, or a mixture of both, are the main ingredients in e-liquid used in electronic cigarettes.
They are aerosolized to resemble smoke and serve as carriers for substances such as nicotine and flavorants.
Miscellaneous applications of Propylene Glycol
As a solvent for many substances, both natural and synthetic.
As a humectant (E1520).
As a freezing point depressant for slurry ice.
In veterinary medicine as an oral treatment for hyperketonaemia in ruminants.[22]
In the cosmetics industry, where propylene glycol is very commonly used as a carrier or base for various types of makeup.
For trapping and preserving insects (including as a DNA preservative).
For the creation of theatrical smoke and fog in special effects for film and live entertainment. Socalled 'smoke machines' or 'hazers' vaporize a mixture of propylene glycol and water to create the illusion of smoke.
While many of these machines use a propylene glycol-based fuel, some use oil.
Those which use propylene glycol do so in a process that is identical to how electronic cigarettes work; utilizing a heating element to produce a dense vapor.
The vapor produced by these machines has the aesthetic look and appeal of smoke, but without exposing performers and stage crew to the harms and odors associated with actual smoke.
As an additive in PCR to reduce the melting temperature of nucleic acids for targeting of GC rich sequences.
as a surfactant, it is used to prevent water from beading up on objects. It is used in photography for this purpose to reduce the risk of water spots, or deposits of minerals from water used to process film or paper.
Propylene Glycol is a synthetic liquid substance that absorbs water.
Propylene Glycol is also used to make polyester compounds, and as a base for deicing solutions.
Propylene Glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food.
The Food and Drug Administration (FDA) has classified Propylene Glycol as an additive that is “generally recognized as safe” for use in food.
Propylene Glycol is used to absorb extra water and maintain moisture in certain medicines, cosmetics, or food products.
Propylene Glycol is a solvent for food colors and flavors, and in the paint and plastics industries.
Propylene Glycol is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions.
Other names for Propylene Glycol are 1,2-dihydroxypropane, 1,2-propanediol, methyl glycol, and trimethyl glycol.
Propylene Glycol is clear, colorless, slightly syrupy liquid at room temperature.
Propylene Glycol may exist in air in the vapor form, although propylene glycol must be heated or briskly shaken to produce a vapor.
Propylene Glycol is practically odorless and tasteless.
At cool temperatures, Propylene Glycol is stable in a well-closed container, but at high temperatures, in the open, Propylene Glycol tends to oxidize, giving rise to products such as propionaldehyde, lactic acid, pyruvic acid, and acetic acid.
Propylene Glycol is chemically stable when mixed with ethanol (95%), glycerin, or water; aqueous solutions may be sterilized by autoclaving.
Use and Manufacturing of Propylene Glycol
Used in antifreeze and deicing solutions for cars, boats, and aircraft; also used as a solvent for paints and plastics and to create harmless, artificial smoke for training and theatrical purposes; [ATSDR ToxFAQs]
Propylene Glycol has become widely used as a solvent, extractant, and preservative in a variety of parenteral and nonparenteral pharmaceutical formulations.
Propylene Glycol is a better general solvent than glycerin and dissolves a wide variety of materials, such as corticosteroids, phenols, sulfa drugs, barbiturates, vitamins (A and D), most alkaloids, and many local anesthetics ...
Propylene Glycol is commonly used as a plasticizer in aqueous film-coating formulations.
Propylene Glycol is also used in cosmetics and in the food industry as a carrier for emulsifiers and as a vehicle for flavors in preference to ethanol, since its lack of volatility provides a more uniform flavor.
Propylene Glycol is used as a skin-conditioning agent-humectant, solvent, viscosity-decreasing agent, and humectant in cosmetic formulations.
Industry Uses of Propylene Glycol
Adhesives and sealant chemicals
Agricultural chemicals (non-pesticidal)
Brazing Paste Component for joining carbon and stainless steel components.
Brazing paste component for joining carbon and stainless steel components.
Carpet
Dyes
Fillers
Finishing agents
Flooring
Functional fluids (closed systems)
Functional fluids (open systems)
Intermediates
Lubricants and lubricant additives
Odor agents
Paint additives and coating additives not described by other categories
Photosensitive chemicals
Pigments
Plastic additive
Plasticizers
Process regulators
Processing aids, not otherwise listed
Processing aids, specific to petroleum production
Solvents (for cleaning and degreasing)
Solvents (which become part of product formulation or mixture)
Surface active agents
Viscosity adjustors
decant water and filtering
metal working fluid and cooling tower fluid
Consumer Uses of Propylene Glycol
Adhesives and sealants
Agricultural products (nonpesticidal)
Air care products
Anti-freeze and de-icing products
Arts, crafts, and hobby materials
Automotive care products
Brazing Paste Component for joining carbon and stainless steel components.
Building/construction materials not covered elsewhere
Cleaning and furnishing care products
Corrosion and scale inhibitors in oilfield
Electrical and electronic products
Fabric, textile, and leather products not covered elsewhere
Food packaging
Golf and Sports Turf
Ink, toner, and colorant products
Laundry and dishwashing products
Lubricants and greases
Non-TSCA use
Paints and coatings
Paper products
Personal care products
Plastic and rubber products not covered elsewhere
Water treatment products
Household Products of Propylene Glycol
Household & Commercial/Institutional Products
Information on 1912 consumer products that contain Propylene Glycol in the following categories is provided:
Auto Products
Commercial / Institutional
Hobby/Craft
Home Maintenance
Inside the Home
Landscaping/Yard
Personal Care
Pesticides
Pet Care
Methods of Manufacturing of Propylene Glycol
Preparation of levorotary Propylene Glycol from hydroxyacetone by yeast reduction.
Propylene Glycol is produced by the non-catalytic liquid-phase hydration of propylene oxide at 100-200 °C.
Manufactured by treating propylene with chlorinated water to form the chlorohydrin, which is converted to the glycol by treatment with sodium carbonate solution.
It is also prepared by heating glycerol with sodium hydroxide.
The only industrial process for manufacturing Propylene Glycol is direct hydrolysis of propylene oxide with water. Dipropylene glycol and tripropylene glycol are formed by sequential addition of propylene oxide to Propylene Glycol. Consequently, all three products are produced simultaneously and separated by distillation.
Propylene Glycol is an important raw material for unsaturated polyester, epoxy resin, and polyurethane resin.
The amount in this area accounts for about 45% of the total consumption of Propylene Glycol.
This unsaturated polyester is used in large quantities for surface coatings and reinforced plastics.
Propylene Glycol has good viscosity and hygroscopicity and is non-toxic, so it is widely used as a moisture absorbent, antifreeze, lubricant, and solvent in food, medicine, and cosmetic industries.
In the food industry, Propylene Glycol and fatty acids react to produce Propylene Glycol fatty acid esters, which are mainly used as food emulsifiers; Propylene Glycol is an excellent solvent for seasonings and pigments.
In the pharmaceutical industry, Propylene Glycol is often used as a solvent, softener, and excipient for the manufacture of various ointments and ointments.
Because Propylene Glycol has good compatibility with various spices, Propylene Glycol is also used as a solvent and softener for cosmetics.
APPLICATIONS:
Food: used for dairy foods, meat foods, baked foods, pasta foods, seasoning foods, flavors, etc.
Industrial manufacturing: petroleum industry, manufacturing, agricultural products, storage batteries, precision castings, etc.
Other products: It can replace glycerin as flavoring, antifreeze, and moisturizer.
Cosmetics: facial cleanser, beauty cream, lotion, shampoo, facial mask, etc.
Feed: canned pets, animal feed, aquatic feed, vitamin feed, etc.
Baked products, meat products, nut products, seasonings, flavor, and aroma enhancers.
Health care products, pharmaceutical excipients, intermediates, extracts.
Propylene glycol, also called propane-1,2-diol, is a synthetic organic compound with the chemical formula C3H8O2.
Propylene Glycol is a viscous colorless liquid with an odorless but slightly sweet taste.
Propylene Glycol is chemically classified as a diol and is miscible with a wide range of solvents such as water, acetone and chloroform.
Propylene Glycol is produced on a large scale and is primarily used in polymer production, but also sees use as a process fluid in food processing and low temperature heat exchange applications.
In the European Union, it has E-number E1520 for food applications.
Propylene Glycol is a clear, colorless and hygroscopic liquid.
Propylene Glycol contains an asymmetric carbon atom, so it exists in two enantiomers.
The commercial product is a racemic mixture. Pure optical isomers can be obtained by hydration of optically pure propylene oxide.
Propylene Glycol is a high purity clear colorless solvent with low volatility, miscible with water, alcohol and ether.
Propylene Glycol is especially suitable for cosmetic applications.
Propylene Glycol is neutral and hygroscopic.
Propylene Glycol is miscible with water in all proportions, less miscible with alcohols, esters and ketones.
Propylene Glycol is a germicide of roughly equal strength to ethanol.
Propylene Glycol stops the reproduction of microorganisms in solutions.
Generally, the desired effect is achieved with a concentration in the range of 15-30%.
Propylene Glycol is produced especially in high purity and odorless in order to meet the needs of the cosmetics industry.
Usage areas of Propylene Glycol
Propylene Glycol is widely used in formulations in bakery products.
Propylene Glycol is used in aroma and essence industry, medicine and cosmetics.
Its technical quality form; Propylene Glycol is an important material for polyurethane plastics and polyester resins. Propylene Glycol is also used in the lubrication of freezer machines in the tobacco industry and food industry.
Mouthwash (mouthwash), toothpastes, ointments, skin creams, shampoos and perfumes (solutions containing propylene glycol usually remain clear even when heavily diluted with water)
As a preservative in cosmetic products in emulsion formation,
As a solvent for fragrances (essences),
As an extractor to extract active extracts from natural extracts,
Propylene Glycol is used as a lubricant (eg for machinery used in the cosmetic industry).
Propylene Glycol has a softening feature on the skin in cosmetics and detergents, Propylene Glycol is used to reduce irritation on the skin from surfactants.
Propylene Glycol is used 1-5% in jelly, 0.5-5% in shampoo, 5-10% in creams, 5-10% in sun milk.
Forty-five percent of the Propylene Glycol produced is used as a chemical feedstock for the production of unsaturated polyester resins.
Propylene Glycol replaces ethylene glycol in low toxicity, environmentally friendly automotive antifreezes.
Propylene Glycol is also used for wintering plumbing systems in empty structures.
Propylene Glycol (also known as propylene glycol, PG, propan1, 2diol and MPG) is a clear, colourless and viscous liquid with a characteristic odour and has the formula C3H8O2. This solvent is soluble in water and holds hygroscopic properties, meaning it can attract hard water molecules.
Propylene Glycol is used across a wide range of industries as Propylene Glycol has low toxicity, coupled with a freezing point which is depressed upon mixing with water.
Propylene Glycol is produced from propylene oxide.
The most common process is by the non-catalytic hydrolysis of propylene oxide in a high-temperature and high-pressure environment.
The second method is the catalytic one, which can proceed at 150 °C, in the presence of ion exchange resin, or a small amount of sulphuric acid or alkali.
Propylene Glycol can also be produced from glycerol which is a bio-diesel by-product.
The demand for, and consumption of, Propylene Glycol is high with an estimated 1.2 million tonnes produced yearly by plants situated around the world.
First Aid Measures of Propylene Glycol
EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.
Be prepared to transport the victim to a hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.
DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.
Hazard classification & labelling of Propylene Glycol
According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
Propylene Glycol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.
Propylene Glycol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Propylene Glycol is used in the following products: anti-freeze products, coating products, fillers, putties, plasters, modelling clay, finger paints and lubricants and greases.
Other release to the environment of Propylene Glycol is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Release to the environment of Propylene Glycol can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and in processing aids at industrial sites.
Other release to the environment of Propylene Glycol is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic
equipment), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use, outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products,
treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Propylene Glycol can be found in complex articles, with no release intended: vehicles.
Propylene Glycol can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys), metal (e.g. cutlery, pots, toys, jewellery), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), plastic (e.g. food packaging and storage, toys, mobile phones), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and leather (e.g. gloves, shoes, purses, furniture).
Propylene Glycol is intended to be released from scented: paper products.
Widespread uses by professional workers
Propylene Glycol is used in the following products: inks and toners, fertilisers, laboratory chemicals, coating products, washing & cleaning products, pH regulators and water treatment products, plant protection products and polymers.
Propylene Glycol is used in the following areas: agriculture, forestry and fishing, building & construction work, printing and recorded media reproduction, health services and scientific research and development.
Propylene Glycol is used for the manufacture of: plastic products and machinery and vehicles.
Other release to the environment of Propylene Glycol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Formulation
Propylene Glycol is used in the following products: washing & cleaning products, laboratory chemicals, inks and toners, perfumes and fragrances, air care products, fertilisers, polishes and waxes, cosmetics and personal care products and coating products.
Release to the environment of Propylene Glycol can occur from industrial use: formulation of mixtures and formulation in materials.
Uses at industry
Propylene Glycol is used in the following products: inks and toners, paper chemicals and dyes, pH regulators and water treatment products, textile treatment products and dyes, washing & cleaning products, coating products, non-metal-surface treatment products and polymers.
Propylene Glycol is used in the following areas: formulation of mixtures and/or re-packaging.
Propylene Glycol is used for the manufacture of: chemicals.
Release to the environment of Propylene Glycol can occur from industrial use: in processing aids at industrial sites, for thermoplastic manufacture, of substances in closed systems with minimal release and as processing aid.
Other release to the environment of Propylene Glycol is likely to occur from: outdoor use as processing aid.
Manufacture
Release to the environment of Propylene Glycol can occur from industrial use: manufacturing of the substance and formulation of mixtures.
