Protectol PE is a high-purity antimicrobial agent based on phenoxyethanol, widely used as a preservative in cosmetics, personal care, and pharmaceutical formulations.
It offers broad-spectrum protection against bacteria, yeasts, and molds, making it a reliable and effective component in preservative systems.
Protectol PE is valued for its low toxicity, stability, and compatibility with a wide range of formulation ingredients.
CAS Number: 122-99-6
EC Number: 204-589-7
Molecular Formula: C₈H₁₀O₂
Molecular Weight: 138.17 g/mol
Synonyms: Protectol PE, Phenoxyethanol, Ethylene glycol monophenyl ether, 2-Phenoxyethanol, Antimicrobial PE, Cosmetic preservative Protectol PE, Phenyl cellosolve, Phenoxytol, Euxyl PE, PE100, Protectol PE preservative, Ethylene glycol phenyl ether, EGPE, Paraben alternative PE, Phenoxy ethanol, Protectol PE antimicrobial agent, Phenyl ethyl glycol ether, Broad-spectrum preservative PE, Protectol phenoxyethanol, Preservative blend component PE, Cosmetic biocide Protectol PE, Protectol PE (BASF), Protectol PE USP grade, PE glycol ether, Protectol PE high-purity grade, Phenoxyethanol USP, Water-soluble preservative PE, Protectol PE (INCI: Phenoxyethanol), Protectol PE 122-99-6, Phenoxyethanol BP grade, Skin care preservative Protectol PE, Hair care preservative Protectol PE
APPLICATIONS
Protectol PE is widely used in creams, lotions, and serums to prevent microbial contamination and extend shelf life.
Protectol PE is included in shampoos, conditioners, and scalp treatments for long-lasting antimicrobial protection.
Protectol PE is employed in baby care products for its gentle preservative action and low irritation profile.
Protectol PE is used in facial cleansers, micellar waters, and toners for safe, non-sensitizing preservation.
Protectol PE is found in wet wipes and cleansing tissues to maintain microbial hygiene and stability.
Protectol PE is incorporated in deodorants and body sprays for product preservation and odor control.
Protectol PE is applied in makeup products such as foundations, mascaras, and eyeliners for extended microbial safety.
Protectol PE is suitable for water-based emulsions and oil-in-water formulations.
Protectol PE is compatible with other preservatives like ethylhexylglycerin for synergistic antimicrobial effect.
Protectol PE is used in pharmaceutical creams, ointments, and topical gels.
Protectol PE is included in household hygiene and personal disinfecting products.
Protectol PE is suitable for natural and paraben-free cosmetic formulations.
Protectol PE is used in the formulation of personal care products, such as shampoos and conditioners, where it serves as a conditioning agent to improve hair manageability, leaving hair soft and shiny.
Protectol PE is employed in the production of moisturizers and skin creams, where it enhances skin hydration and promotes a smooth, non-greasy finish.
Protectol PE is applied in the production of sunscreens, where it helps stabilize the formulation and enhance the product's ability to protect the skin from harmful UV rays.
Protectol PE is used in the formulation of body lotions and body washes, where it provides a silky smooth texture, improving product spreadability and skin absorption.
Protectol PE is used in the development of anti-aging skin care products, where it helps to hydrate the skin and promote a more youthful, plump appearance.
Protectol PE is used in the production of lip care products, such as lip balms and glosses, where it helps to moisturize and protect the lips from dryness and chapping.
Protectol PE is employed in the formulation of baby care products, where it provides gentle skin hydration and protection, ideal for sensitive skin.
Protectol PE is used in the preparation of after-sun care products, where it helps to soothe and moisturize the skin after exposure to sun and environmental stressors.
Protectol PE is applied in the formulation of facial masks, where it helps to improve product texture, ensuring smooth application and better ingredient absorption.
Protectol PE is used in the production of facial scrubs and exfoliating products, where it improves the spreadability of exfoliating particles and enhances the effectiveness of the scrub.
Protectol PE is used in the formulation of deodorants, where it contributes to a smoother application, preventing irritation while providing long-lasting moisture and protection.
Protectol PE is used in the production of skin toners, where it helps hydrate the skin while improving texture and balance.
Protectol PE is employed in the formulation of anti-inflammatory skin care products, where it helps soothe and calm irritated skin while providing moisture.
Protectol PE is used in the production of wound healing products, where it promotes skin regeneration, preventing dryness and improving skin recovery.
Protectol PE is applied in the formulation of shaving creams, where it helps create a creamy, rich lather and leaves the skin feeling smooth and hydrated after shaving.
Protectol PE is used in the development of hair styling products, such as gels and mousses, where it helps improve texture and enhance product performance while keeping hair hydrated.
Protectol PE is employed in the production of exfoliating lotions, where it helps emulsify the product and ensure consistent, even exfoliation while maintaining skin hydration.
Protectol PE is used in the formulation of hair treatments, where it helps condition the hair, improve its texture, and reduce frizz.
Protectol PE is applied in the production of anti-cellulite creams, where it helps hydrate the skin while improving the overall texture and appearance of the skin.
Protectol PE is used in the formulation of acne treatments, where it helps hydrate the skin without clogging pores, ensuring that other active ingredients work effectively.
Protectol PE is used in the production of foot creams, where it helps to moisturize and protect dry, cracked skin, leaving the feet soft and smooth.
Protectol PE is employed in the preparation of hand creams, where it helps protect the skin from drying out while providing long-lasting hydration.
Protectol PE is used in the formulation of skin protection creams, where it helps prevent skin dehydration and irritation caused by environmental factors.
Protectol PE is used in the production of anti-pollution skin care products, where it helps to protect the skin from damage caused by pollutants while maintaining hydration.
Protectol PE is employed in the formulation of skin whitening creams, where it helps to moisturize the skin and contribute to an even skin tone by keeping it hydrated.
Protectol PE is used in the development of anti-acne moisturizers, where it helps hydrate the skin while controlling oil production, preventing acne outbreaks.
Protectol PE is used in the production of bath oils, where it emulsifies the oils in water, allowing them to evenly distribute and provide a moisturizing bath experience.
Protectol PE is applied in the formulation of baby wipes, where it helps hydrate the skin while ensuring the wipes remain gentle on sensitive skin.
Protectol PE is used in the production of solubilizers for fragrances in personal care products, where it ensures even distribution and stability of scents.
Protectol PE is employed in the formulation of hand sanitizers, where it helps hydrate the skin while enhancing the product's moisturizing effect.
DESCRIPTION
Protectol PE is a clear, colorless, slightly viscous liquid with a mild rose-like odor.
It is a glycol ether derivative of phenol and ethylene oxide, known for its broad-spectrum antimicrobial efficacy.
Protectol PE exhibits excellent solubility in water, alcohols, and glycols, facilitating easy formulation in diverse systems.
Protectol PE is effective against gram-positive and gram-negative bacteria, fungi, and yeasts, even at low concentrations.
It remains stable over a wide pH range (3–10) and does not degrade under heat or light in typical cosmetic conditions.
Protectol PE has low sensitization potential, making it suitable for sensitive skin and daily-use products.
Protectol PE functions as both an antimicrobial agent and solvent in formulations, enhancing ingredient solubility.
It supports formulation safety without compromising skin feel, color, or fragrance.
Protectol PE complies with cosmetic regulations in the EU, US, and other major markets.
Protectol PE is a mild, skin-conditioning agent derived from natural oils, used widely in personal care products for its ability to provide moisture and improve texture.
Protectol PE is a versatile ingredient commonly used in emulsions, where it helps enhance product texture, improve spreadability, and provide a smooth, non-greasy finish.
Protectol PE is a colorless to pale yellow liquid, known for its excellent ability to hydrate and condition the skin and hair without leaving a greasy residue.
Protectol PE works by creating a barrier that helps to lock moisture into the skin, making it an essential ingredient in formulations designed for dry or dehydrated skin.
Protectol PE is biodegradable and environmentally friendly, making it a preferred choice for eco-conscious formulations in the personal care industry.
Protectol PE is stable across a wide range of pH values, which makes it suitable for use in various formulations, including lotions, creams, shampoos, and conditioners.
Protectol PE is commonly used in conjunction with other active ingredients to improve their absorption, ensuring that they penetrate the skin more effectively for better results.
Protectol PE is safe for use in products for sensitive skin, including baby care products, due to its gentle, non-irritating properties.
PROPERTIES
Chemical Formula: C₈H₁₀O₂
Molecular Weight: 138.17 g/mol
Common Name: Phenoxyethanol (Protectol PE)
Appearance: Clear, colorless liquid
Odor: Mild, floral-like odor
Solubility: Soluble in water, ethanol, and glycols
Boiling Point: Approx. 247°C
Melting Point: -2°C
Density: Approx. 1.10 g/cm³
Flash Point: Approx. 121°C (closed cup)
Stability: Stable across pH 3–10; thermally stable
Storage Temperature: Store between 10–25°C in sealed containers
Shelf Life: 24–36 months in original packaging
FIRST AID
Inhalation:
Move person to fresh air.
Seek medical attention if symptoms occur.
Skin Contact:
Wash skin thoroughly with soap and water.
Seek medical help if irritation or allergic reaction develops.
Eye Contact:
Rinse eyes with water for at least 15 minutes.
Consult a physician if irritation persists.
Ingestion:
Rinse mouth with water.
Seek medical attention immediately if a large amount is swallowed.
Note to Physicians:
Treat symptomatically.
Low acute toxicity but observe for delayed effects.
HANDLING AND STORAGE
Handling:
Use personal protective equipment in bulk or industrial settings.
Avoid inhalation of vapors and contact with eyes or mucous membranes.
Use in well-ventilated areas.
Spill and Leak Procedures:
Absorb with inert material and clean spill area thoroughly.
Dispose of waste according to local regulations.
Storage:
Store Protectol PE in tightly sealed containers away from strong oxidizing agents.
Keep in a dry, cool, and well-ventilated area, away from direct sunlight.
Ensure storage containers are properly labeled and protected.
Handling Cautions:
Avoid contamination and overexposure.
Follow GMP and safety protocols during handling and mixing.