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Provichem 0321 is a degradation product of Bis(2-Chloroethyl) Ether.
Provichem 0321 is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).
Provichem 0321 is a multi-walled carbon with an amino function and two hydroxyl groups.
CAS: 628-89-7
MF: C4H9ClO2
MW: 124.57
EINECS: 211-059-9
Provichem 0321 Chemical Properties
Boiling point: 79-81 °C5 mm Hg(lit.)
Density: 1.18 g/mL at 25 °C(lit.)
Vapor pressure: 22.66Pa at 20℃
Refractive index: n20/D 1.452(lit.)
Fp: 195 °F
Storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Solubility: SOLUBLE
Form: Liquid
pka: 14.34±0.10(Predicted)
Color: Clear
Water Solubility: SOLUBLE
BRN: 506015
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: LECMBPWEOVZHKN-UHFFFAOYSA-N
LogP: 0.301 at 30℃
CAS DataBase Reference: 628-89-7(CAS DataBase Reference)
NIST Chemistry Reference: Provichem 0321 (628-89-7)
EPA Substance Registry System: Provichem 0321 (628-89-7)
Uses
Provichem 0321 is a degradation product of Bis(2-Chloroethyl) Ether.
Provichem 0321 is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).
Provichem 0321 is employed in the preparation of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine and 2-(2-azidoethoxy)ethanol.
Provichem 0321 is used in the preparation of industrial chemicals such as piperazine, azobenzene, and caproic acid.
Provichem 0321 is also used in the synthesis of blood group antigens.
The oxygen atoms of the methylene group are involved in intramolecular hydrogen bonds with the carbonyl group and the hydroxyl groups.
The phase transition temperature for Provichem 0321 is between −30°C and −10°C, which makes it useful for magnetic resonance spectroscopy.
Synonyms
2-(2-CHLOROETHOXY)ETHANOL
628-89-7
Ethanol, 2-(2-chloroethoxy)-
Diglycol chlorohydrin
2-(2-chloroethoxy)ethan-1-ol
Diglycol chlorhydrin
2-Chloroethyl 2-hydroxyethyl ether
Diethylene glycol monochlorohydrin
2-(2'-Chloroethoxy)ethanol
2-(2-chloroethoxy) ethanol
Ethylene Glycol Mono-2-chloroethyl Ether
2-(2-chloro-ethoxy)-ethanol
R2UP818L4I
NSC-2648
52137-03-8
NSC 2648
EINECS 211-059-9
C4H9ClO2
BRN 0506015
UNII-R2UP818L4I
AI3-14497
diethylene chlorohydrin
2(2-chloroethoxy)ethanol
ClCH2CH2OCH2CH2OH
WLN: QZO2G
2(2-chloroethoxy) ethanol
EC 211-059-9
SCHEMBL9111
2-(2-chloroethoxyl)ethanol
2-(2-chloro ethoxy)ethanol
2-(2-chloroethoxy)-ethanol
5-Chloro-3-oxa-1-pentanol
2-(2-chloroethoxyl)-ethanol
3-01-00-02078 (Beilstein Handbook Reference)
2-[(2-Chloroethyl)oxy]ethanol
DTXSID9060861
LECMBPWEOVZHKN-UHFFFAOYSA-
AMY9387
NSC2648
2-(2-Chloroethoxy)ethanol, 99%
2-(2-Hydroxyethoxy)ethyl chloride
BCP21810
ZINC1641057
MFCD00002870
AKOS009156883
GS-3037
Ethylene Glycol Mono(2-chloroethyl) Ether
DB-019394
CS-0016058
FT-0608446
EN300-52467
A25076
D72518
Q-200138
Q27287714
Diglycol chlorohydrin pound>>Ethanol, 2-(2-chloroethoxy)-
2-(2-chloroethoxy)-ethano;2-Chloro-2'-hydroxydiethylether;2-Chloroethyl 2-hydroxyethyl ether
