Quick Search

PRODUCTS

PROVIPLAST 2624

Proviplast 2624 is a hydrophobic biodegradable plasticizer, that is usually synthesized by esterification of citric acid. 
Pharmaceutically, Proviplast 2624 is used as an excipient, which is generally applied as a thin film over the tablets or capsules.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

CAS:    77-90-7
MF:    C20H34O8
MW:    402.48
EINECS:    201-067-0

Proviplast 2624 is aqueous-based pharmaceutical coat- ings.
Proviplast 2624 is an excellent choice in specialty applications such as food contact cling film.
Proviplast 2624 can also be used as co-plasticizer in applications like flooring and conveyor belts.
Proviplast 2624 is tributyl 2-acetylcitrate. 
Acts as a partially bio-based, general purpose plasticizer. 
Shows excellent flexibility at low temperature, improved stability at high temperature and good UV stability. 
Offers high efficiency, transparency and excellent processability. 
Proviplast 2624 is an effective plasticizer for PVC, PVC copolymers, acrylics and cellulosics. 
Proviplast 2624 is designed for seal closures for food containers including drink bottle caps and food jar caps, gasket sealants and cling films. 
Proviplast 2624 can also be used as co-plasticizer in flooring and conveyor belts. 
Proviplast 2624 is approved by the FDA for direct and indirect food contact applications according to CFR21. 
Proviplast 2624 has a shelf life of 2 years.
From citric acid via the tributyl ester followed by acetylation.

Proviplast 2624 should be stored in a well-closed container in a cool, dry location at temperatures not exceeding 38℃. 
When stored in accordance with these conditions, Proviplast 2624 is a stable product.

Proviplast 2624 is a citrate ester with a broad field of applications, mainly used as plasticizer, to prepare flavours, in essence formulations and cosmetics. 
Due to its versatility, low volatility and safety, Proviplast 2624 can help in replacing phthalates in numerous applications.

Plasticizers are used to make plastic softer and more flexible. 
The most commonly used plasticizers for PVC are phthalates. 
However, there are concerns regarding toxicity of certain phthalates. 
This causes an increasing pressure from both public authorities and customers to shift toward the use of phthalate-free alternatives. 
Proviplast 2624 is helping this transition by offering high-quality non-phthalate plasticizers.

Proviplast 2624 is a non-phthalate plasticizer that is an excellent choice in specialty applications such as food contact cling film. 
Proviplast 2624 can also be used as co-plasticizer in applications like flooring and conveyor belts.

Proviplast 2624 is reportedly used as a flavor ingredient in nonalcoholic beverages at a concentration of 1.0 ppm. 
A monitoring study of hospital diets in Japan for plasticizers in hospital food detected Proviplast 2624 at levels (in one hospital) that corresponded to a daily intake of 1228 ug/day; the source of the acetyl tributyl citrate in the food was suspected to be cling-film wrapping or other packaging. 
Monitoring tests determined that Proviplast 2624 plasticizer in plastic films migrated from the film into cooked poultry meat during microwave cooking.

Proviplast 2624 is an organic compound that is used as a plasticizer. 
As such, Proviplast 2624 is a potential replacement of DEHP and DINP.
Proviplast 2624 is a colorless liquid that is soluble in organic solvents. 
Proviplast 2624 is found in nail polish and other cosmetics. 
Proviplast 2624 is prepared by acetylation of tributylcitrate.

Proviplast 2624 is synthesized by esterification of citric acid and n-butanol under the action of catalyst. 
The raw materials of Proviplast 2624 are acetic acid, citric acid and n-butanol. 
Proviplast 2624 is a non-toxic and odorless main plasticizer. 
Proviplast 2624 is less toxic than TBC. 
Proviplast 2624 as the main plasticizer, has strong solubility, oil resistance, light resistance, and has a good mildew resistance. 
Proviplast 2624 has good compatibility with most cellulose, polyvinyl chloride, polyvinyl acetate and so on. 
Proviplast 2624 is mainly used as plasticizer of cellulose resin and vinyl resin. 
In the aspect of children's toys, DOP is prohibited in more and more fields with the continuous discovery of DOP toxicity data, while Proviplast 2624 is non-toxic, odorless, transparent, low water extraction rate, plasticizing plastic products with good processing performance, good thermal bonding, convenient secondary processing, especially suitable for the use of children's toys as the main plasticizer. 

In meat packaging, Proviplast 2624 is non-toxic and can be used as meat packaging material, while DOP cannot be used in food packaging with high fat content. 
And Proviplast 2624 tasteless, will not cause food odor, through its plasticized plastic products transparent, good printing performance. 
In medical products, Proviplast 2624 is non-toxic, low water extraction rate, no potential harm to human body, its plasticized medical products have good high temperature resistance and low temperature performance.
As an excellent plasticizer, Proviplast 2624 not only meets the requirement of non-toxic plasticizer, but also can be used in general plastic products. 
Cellulose film plasticized with Proviplast 2624 has a lower volatility loss and a stronger adhesion to metals than cellulose film containing DBP.

Proviplast 2624 Chemical Properties
Melting point: -59 °C
Boiling point: 327 °C
Density: 1.05 g/mL at 25 °C (lit.)
Vapor pressure: 0.26 psi ( 20 °C)
Refractive index: n20/D 1.443(lit.)
FEMA: 3080 | TRIBUTYL ACETYLCITRATE
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: Not miscible with water, miscible with ethanol (96 per cent) and with methylene chloride.
Form: neat
Color: Clear Colourless
Water Solubility: <0.1 g/100 mL
FreezingPoint: -80℃
JECFA Number: 630
BRN: 2303316
InChIKey: QZCLKYGREBVARF-UHFFFAOYSA-N
CAS DataBase Reference: 77-90-7(CAS DataBase Reference)
NIST Chemistry Reference: Proviplast 2624 (77-90-7)
EPA Substance Registry System: Proviplast 2624 (77-90-7)

Proviplast 2624 is a clear, odorless, practically colorless, oily liquid.
Proviplast 2624 has a very faint, sweet, herbaceous odor. 
At high levels (e.g., 1000 ppm emulsion in water), Proviplast 2624 has a mild, fruity, nondescript flavor.
Proviplast 2624 is a colorless, odorless liquid. 
Proviplast 2624's water solubility is less than 0.002 g/100 mL, but it is soluble in organic solvents.

Uses    
These Secondary Standards are qualified as Certified Reference Materials. 
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Topical pharmaceutical formulation anesthetic surfactant ester.
Proviplast 2624 is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations.

1. Proviplast 2624 is a non-toxic, odorless and safe plasticizer with excellent heat resistance, cold resistance, light resistance and water resistance. 
Proviplast 2624 is suitable for food packaging, children’s toys, medical products and other fields.
2. American F.D.A approved Proviplast 2624 for meat packaging materials and toy materials. Due to its excellent performance, Proviplast 2624 is widely used in packaging of fresh meat and its products, packaging of dairy products, polyvinyl chloride medical products, chewing gum, etc.
3. The resin is plasticized with Proviplast 2624 and exhibits good transparency and low-temperature deflection performance, and has low volatility and extraction rate in different media.
Proviplast 2624 is thermally stable and does not change color during melting and sealing.

Production Methods    
Proviplast 2624 is prepared by the esterification of citric acid with butanol followed by acylation with acetic anhydride.

Carcinogenicity    
The chronic toxicity of Proviplast 2624 was evaluated in rats fed diets containing 200, 2000, or 20,000 ppm of ATBC for 2 years. 
There were no treatment- related lesions in any organs examined.

Proviplast 2624 plasticizer effect
1. Lower the glass transition temperature of the polymer.
2. Change the structure of the polymer to make the plasticized material soft.
3. Increase the elongation of the polymer and reduce the tensile strength.
4. Increase the toughness of the polymer and improve the impact resistance.
5. Improve low temperature performance.
6. Reduce the viscosity of the polymer and improve the processability of the polymer and its compounding mixture.
7. Change the rheological properties of polymers, especially those with high polymer content in the products.

Synonyms
77-90-7
ACETYL TRIBUTYL CITRATE
tributyl 2-acetoxypropane-1,2,3-tricarboxylate
Acetyltributyl citrate
Tributyl acetylcitrate
Tributyl O-acetylcitrate
Citroflex A
Blo-trol
Citroflex A 4
2-Acetyltributylcitrate
Tributyl citrate acetate
ATBC
1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester
Tributyl acetyl citrate
FEMA No. 3080
acetyltributylcitrate
Acetylcitric acid, tributyl ester
Tributyl acetylicitrate
Citric acid, tributyl ester, acetate
o-Acetylcitric acid tributyl ester
NSC 3894
Uniplex 84
Tributyl 2-acetoxy-1,2,3-propanetricarboxylate
Acetyl butyl citrate
tributyl 2-acetyloxypropane-1,2,3-tricarboxylate
Tributyl 2-(acetyloxy)-1,2,3-propanetricarboxylate
2-Acetoxy-1,2,3-propanetricarboxylic acid tributyl ester
NSC-3894
Acetyl tri-n-butyl citrate
0ZBX0N59RZ
DTXSID2026446
1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, 1,2,3-tributyl ester
DTXCID006446
Tributyl 2-(acetyloxy)-1,2,3-propanetricarboxylic acid
1,2,3-Propanetricarboxylic acid, 2-acetoxy-, tributyl ester
Caswell No. 005AB
MFCD00043554
CAS-77-90-7
CCRIS 3409
HSDB 656
EINECS 201-067-0
UNII-0ZBX0N59RZ
Acetyltributyl citrate [NF]
BRN 2303316
Estaflex
AI3-01999
Estaflex ATC
C20H34O8
Pfizer citroflex A-4
tributyl-o-acetyl citrate
Acetylcitric acid tributyl
EC 201-067-0
SCHEMBL23183
Tributyl O-acetylcitrate, 98%
CHEMBL1904556
Acetyl Tributyl Citrate (ATBC)
FEMA 3080
NSC3894
CHEBI:168067
Citric acid, acetyl tributyl ester
ACETYLTRIBUTYL CITRATE [II]
2-(Acetyloxy)-1,2,3-propanetricarboxylic acid, tributyl ester
ZINC3875493
Tox21_112777
Tox21_201779
Tox21_303128
ACETYLTRIBUTYL CITRATE [HSDB]
TRIBUTYL ACETYLCITRATE [FHFI]
ACETYL TRIBUTYL CITRATE [INCI]
AKOS015895884
TRIBUTYL ACETYLCITRATE [MART.]
ACETYLTRIBUTYL CITRATE [USP-RS]
CS-W011697
Tributyl 2-acetylcitrate, >=98%, F
NCGC00164157-01
NCGC00164157-02
NCGC00257221-01
NCGC00259328-01
BS-18149
NCI60_003698
CITRIC ACID, O-ACETYLTRIBUTYL ESTER
A0822
Citric acid, tributyl ester, acetate (8CI)
FT-0621820
Tributyl 2-acetoxy-1,3-propanetricarboxylate
TRIBUTYL ACETYLCITRATE [EP MONOGRAPH]
D70155
Tributyl 2-acetoxy-1,2, 3-propanetricarboxylate
A839285
SR-01000883988
Q4673294
SR-01000883988-1
Tributyl 2-(acetyloxy)-1,3-propanetricarboxylic acid
2-Acetoxy-1,3-propanetricarboxylic acid tributyl ester
Tributyl 2-(acetyloxy)-1,2, 3-propanetricarboxylic acid
1,2,3-tributyl 2-(acetyloxy)propane-1,2,3-tricarboxylate
2-Acetoxy-1,2, 3-propanetricarboxylic acid tributyl ester
1,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester
2-(Acetyloxy)-1,2,3-propane tricarboxylic acid, tributyl ester
2-ACETYLOXY-1,2,3-PROPANETRICARBOXYLIC ACID TRIBUTYL ESTER
Acetyltributyl citrate, United States Pharmacopeia (USP) Reference Standard
Tributyl acetylcitrate, European Pharmacopoeia (EP) Reference Standard
Tributyl 2-acetylcitrate, Pharmaceutical Secondary Standard; Certified Reference Material

  • Share !
E-NEWSLETTER