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CAS Number: 2634-33-5
PROXEL GXL is a 20% aqueous dipropylene glycol solution of 1,2-benzisothiazolin-3-one.
PROXEL GXL is Used for the preservation of industrial water-based products against spoilage from bacteria, yeasts and fungi.
PROXEL GXL has a non-specific mode of action which means that bacterial resistance is very unlikely to occur.
PROXEL GXL boils without flashing and is stable in the presence of amines.
The concentration of PROXEL GXL required to adequately preserve your product depends on several factors.
These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.
Suitable for use in synthetic polymer emulsions, emulsion paints, printing inks, paper coating compositions.
PROXEL GXL Preservative is effective in a wide range of industrial aqueous-based products such as emulsion paints, water-based adhesives, household products, printing inks, paper coating compositions, metal working fluids, agricultural pesticide dispersions.
PROXEL GXL is a broad-spectrum biocide for the preservation of water-based products against spoilage from bacteria, yeasts and fungi.
PROXEL GXL is a 20% aqueous dipropylene glycol solution of 1,2-benzisothiazolin-3-one.
PROXEL GXL is effective in aqueous-based household products.
The PROXEL GXL Material Safety Data Sheet is provided with every sample and product shipment and is also supplied upon request.
PROXEL GXL should be read and understood by all supervisory personnel and employees before using this product.
PROXEL GXL is an anti-bacterial, 19.3% active content, Formaldehyde free glycol/alcohol solution suitable for all types of formulations.
PROXEL GXL Preservative, an aqueous solution of 1, 2- benzisothiazolin3-one, is an efficient microbiostat preservative for aqueous compositions such as oil in water emulsions.
PROXEL GXL is registered with the Environmental Protection Agency and has been granted EPA Registration No. 1258-1255.
Many aqueous dispersions and emulsions can be seriously impaired during storage and use due to the growth in them of bacteria and fungi.
PROXEL GXL is an effective preservative against growth of the above microbial agents in the aqueous systems listed and exhibits:
Effective control of a wide range of organisms at economic concentrations.
Long-term storage stability.
Ease of use due to PROXEL GXL liquid form and good compatibility in most aqueous composition.
Uses of PROXEL GXL:
Oil-in-Water Emulsions:
“Spin finish” solutions for use in the textile industry.
Cutting/rolling oils.
Soluble oils (metal and engineering industries).
Emulsion Paint and Coatings:
Including varnishes, lacquers and stains: For preservation in the can.
Adhesives:
Carboxymethylcellulose (CMC)and derivatives, animal glues, adhesives based on gelatins and latex.
Paper Coating Compositions:
Rosin dispersions.
Starch and casein based products.
Pesticide Formulations:
For product preservation For use – dilution
Preservation of Fresh Animal Hides and Skins:
To preserve the integrity of fresh animal hides and skins prior to or during processing, use 13 fluid ounces to 2.5 gallons (1.0-24 lbs) of PROXEL GXL Preservative per 1000 pounds of hides or skins.
Add the appropriate quantity of PROXELGXL Preservative to the brine solution during the curing operation or treat hides or skins with an appropriately diluted aqueous solution during other portions of the processing operation.
The specific use rate and contact time needed to control microbial attack will depend upon the degree of decomposition of the hides or skins prior to treatment.
Leather Processing Solutions:
Use PROXEL GXL Preservative at levels of 0.025-0.2% for the preservation of leather processing solutions.
General Recommendations of PROXEL GXL:
The concentration required to give protection depends on several factors.
These include the susceptibility of the system to microbiological degradation, the extent to which microorganisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.
For protection against bacterial attack, a concentration within the range 0.02-0.35% PROXEL GXL Preservative is almost invariably sufficient.
The control of mold growth, particularly on paste products of high solids content, may occasionally demand dosages above 0.25%.
In dilute fluid systems, spoilage is usually controlled with dosages not greater than 0.09%.
Applications of PROXEL GXL:
PROXEL GXL is effective in a wide range of industrial aqueous-based products.
Application Areas Include:
Synthetic polymer emulsions,
Emulsion paints,
Water-based adhesives,
Household products,
Printing inks,
Paper coating compositions,
Metal working fluids,
Agricultural pesticide dispersions,
Aqueous mineral and pigment slurries,
Tape joint compounds,
Leather processing solutions,
Lattices,
Oil-in-water emulsions,
Emulsion paint and coatings,
Adhesives,
Paper coating compositions,
Pesticide Formulations,
Home Cleaning products,
Laundry additives.
Amount to Use of PROXEL GXL:
PROXEL GXL should be added to the system as early in the process as possible.
The concentration of PROXEL GXL required to adequately preserve your product depends on several factors.
These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.
A range of concentrations and applications is recommended in stated below.
However, PROXEL GXL is recommended that a testing programme be undertaken to determine the most costeffective dose for your application.
Testing should take into account chemical compatibility/stability, plant hygiene conditions, susceptibility of the product to contamination, and the typical organisms involved.
Product % PROXEL GXL (w/w)
Synthetic polymer emulsions: 0.05-0.15
Emulsion paints: 0.05-0.15
Water-based adhesives: 0.05-0.25
Household products: 0.05-0.15
Including Laundry detergents, Fabric softeners, Dish-washing liquids, Floor and wall cleaning solutions, Surface cleaning products, Window cleaners, Floor polishes and waxes, Shoe polishes.
Tape joint compounds: 0.05-0.25
Printing inks: 0.05-0.15
Paper coating compositions: 0.05-0.15
Metal working fluids: 0.05-0.18
Agricultural pesticide products: 0.05-0.25
Aqueous mineral and pigment slurries: 0.05-0.15
Leather processing solutions: 0.05-0.25
For the short term preservation of freshly flayed skins & hides during processing.
Antimicrobial Properties of PROXEL GXL:
The levels of PROXEL GXL needed to prevent the growth of problem micro-organisms are listed in stated below.
MICs do not represent effective use levels but do indicate the broad spectrum of activity of PROXEL GXL.
PROXEL GXL has a non-specific mode of action which means that bacterial resistance is very unlikely to occur.
Detailed information on the mode of action of PROXEL GXL is available on request.
Minimum Inhibitory Concentrations (MIC)
Micro-organism PROXEL GXL (ppm)
Bacteria:
Bacillus subtilis - 40
Burkholderia cepacia - 80
Enterobacter cloacae - 80
Escherichia coli - 40
Proteus vulgaris - 125
Pseudomonas aeruginosa - 250
Pseudomonas putida - 250
Staphylococcus aureus - 40
Streptococcus faecalis - 40
Streptococcus lactis - 15
Fungi:
Alternaria alternata - 700
Aspergillus niger - 350
Aureobasidium pullulans - 350
Chaetomium globosum - 400
Cladosporium cladosporoides - 400
Penicillium notatum - 125
Yeasts:
Candida albicans - 200
Rhodotorula rubra - 400
Saccharomyces cerevisiae (turbidans) - 250
Typical Physical Properties of PROXEL GXL:
Composition A solution of 1,2-benzisothiazolin3-one in dipropylene glycol and water.
Active agent 20% w/w
Physical form: Yellow-light brown solution
Viscosity at 10/25°C: 2000/400 mPa s (Newtonian)
pH at 25°C: 13.5
Boiling point: 100°C
Storage stability: Stable under normal conditions of storage down to -10°C. If frozen, allow to thaw and stir well before use.
Active agent is heat-stable and non-volatile.
Flash point: Boils without flashing
Density at 25°C: 1.14
Compatibility: Compatible and effective over pH range 4-12.
Stable in the presence of amines.
Incompatible with some oxidising and reducing agents e.g. persalts, sulphites
Physical Form and Appearance: Liquid
Viscosity (25°C) Brookfield: 500 centipoise (approx.)
Specific Gravity (25°C/25°C): 1.13 (approx.)
pH (25°C): 12 (approx.)
Density (25°C): 9.5 lb/gal (approx.)
Initial Boiling Point :100°C
Solubility: Soluble in water at use dilutions
Stability: Stable under all normal storage conditions.
Maintain the pH above approximately 4.
The active agent is heat stable and non-volatile.
Protect from frost.
Synonyms of PROXEL GXL:
1,2-benzisothiazolin-3-one
1,2-benzisothiazoline-3-one
benzisothiazolinone
benzisothiazolone
Proxel
1,2-Benzisothiazol-3(2H)-one
2634-33-5
1,2-Benzisothiazolin-3-one
1,2-benzothiazol-3-one
benzisothiazolone
benzisothiazolinone
Benzo[d]isothiazol-3(2H)-one
Benzo[d]isothiazol-3-one
Proxel
1,2-Benzisothiazoline-3-one
Proxel PL
Benzo[d]isothiazol-3-ol
2,3-dihydro-1,2-benzothiazol-3-one
1,2-benzisothiazolinone
Nipacide BIT
Proxel AB
Proxel XL 2
1,2-BENZISOTHIAZOL-3-ONE
benzoisothiazol-3-one
1,2-benzoisothiazolin-3-one
1,2-Benzisothiazolone
C7H5NOS
CCRIS 6369
3-Hydroxy-1,2-benzisothiazole
IPX
CHEBI:167099
EINECS 220-120-9
HRA0F1A4R3
1,2-Benzoisothiazoline-3-one
40991-37-5
2,3-dihydro-3-oxo-1,2-benzisothiazole
Benzo(d)isothiazol-3(2H)-one
Benzisothiazolin-3-one
Benzocil
Acticide BIT
Canguard BIT
Denicide BIT
Proxel BD
Proxel CF
Proxel TN
Proxel XL
Proxel BDN
PROXEL GXL
Proxel Ultra 5
San-aibac AP
Proxel LV-S
Proxel Press Paste
Apizas AP-DS
Acticide BW 20
Bestcide 200K
Nipacide BIT 20
Parmetol B 70
Parmetol D 11
PROXEL GXL(S)
Proxel HL 2
Nuosept 485
Nuosept 491
Nuosept 495
Topcide 600
XBINX
Denicide BIT 20N
Koralone B 119
Nipacide BIT 10W
Preventol BIT 20D
Proxel BD 20
Proxel Press Paste D
Troysan 1050
Bioban BIT 20DPG
1,2-benzisothiazole-3(2h)-one
benzisothiazoline-3-one
Canguard BIT 20DPG
SD 202 (bactericide)
Canguard Ultra BIT 20LE
1,2-Benzoisothiazol-3-one
BIT 10W
BIT 20
2-Thiobenzimide
2,3-Dihydrobenzisothiazol-3-one
1,2-Benzothiazolinone
Benzisothiazolone (BIT)
Benzisothiazol-3(2H)-one
1,2-benzothiazol-3(2h)-one
1,2-benzisothiazol-3(2H)-on
1,2-BIT
1,2-Benzisothiazol-3-one (BIT)
1,2-BENZISOTHAZOL-3(2H)-ONE
1,2-Benzisothiazol-3(2H)-one, 97%
CAS-2634-33-5
1,2-Benzisothiazol-3(2H)-one, analytical standard
75037-67-1
1,2-Benzisothiazol-3(2H)-one
1,2-Benzisothiazolin-3-one
1,2-Benzisothiazoline-3-one
2,3-dihydro-3-oxo-1,2-benzisothiazole
benzisothiazolone
BIT
IPX
1,2-Benzisothiazol-3(2H)-one
1,2-Benzisothiazoline-3-one
benzisothiazolone
1,2-Benzisothiazolin-3-one
2,3-dihydro-3-oxo-1,2-benzisothia
1,2-Benzisothiazol-3(2H)-one [ACD/Index Name]
1,2-Benzisothiazol-3-ol [ACD/Index Name]
1,2-Benzothiazol-3(2H)-on [German] [ACD/IUPAC Name]
1,2-Benzothiazol-3(2H)-one [ACD/IUPAC Name]
1,2-Benzothiazol-3(2H)-one [French] [ACD/IUPAC Name]
1,2-Benzothiazol-3-ol [German] [ACD/IUPAC Name]
1,2-Benzothiazol-3-ol [ACD/IUPAC Name]
1,2-Benzothiazol-3-ol [French] [ACD/IUPAC Name]
220-120-9 [EINECS]
2634-33-5 [RN]
BENZISOTHIAZOLINONE
Benzisothiazolone [Wiki]
Benzisothiazolone (BIT)
benzo[d]isothiazol-3-one
[2634-33-5]
1,2-BENZISOTHAZOL-3(2H)-ONE
1,2-Benzisothiazol-3-one
1,2-Benzisothiazolin-3-one
1,2-Benzisothiazolinone
1,2-Benzisothiazolone
1,2-benzoisothiazolin-3-one
1,2-Benzoisothiazoline-3-one
1,2-Benzothiazol-3-one
1,2-Benzothiazolinone
119510
2,3-dihydro-1,2-benzothiazol-3-one
2,3-dihydro-3-oxo-1,2-benzisothiazole
2634-33-5
2-hydrobenzo[d]isothiazol-3-one
2-Thiobenzimide
3-Hydroxy-1,2-benzisothiazole
54392-15-3 [RN]
75037-67-1 [RN]
9015-68-3 [RN]
Acticide BIT
Benzisothiazol-3(2H)-one
BENZISOTHIAZOLINONE|"1,2-BENZOTHIAZOL-3-OL"
Benzo(D) Isothiazol-3-one
benzo[d]isothiazol-3(2H)-one
Benzo[d]isothiazol-3-ol
Benzoisothiazol-3-one
Benzoisothiazol-3-one|1,2-Benzisothiazol-3(2H)-one|3-Hydroxy-1,2-benzisothiazole
BIT
BR-46705
EINECS 220-120-9
IPX
Nipacide BIT
proxan
Proxel
Proxel AB
Proxel PL
Proxel XL 2
2,3-dihydro-1,2-benzothiazol-3-one
1,2-benzisothiazol-3(2H)-one
Benzisothiazolin-3-one
Benzisothiazolone
Benzisothiazolinone
1,2-benzisothiazoline-3-one
