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PVP K-17

 


CAS NO:9003-39-8
EC NO:618-363-4
Molecular Formula: (C6H9NO)n


PVP-K17 white powder or aqueous solution. 
PVP-K17 is easily dissolved in water, alcohol, amine and halohydrocarbon, but not dissolved in acetone and aether etc... 
PVP-K17 has good solubility, biocompatibility and physiologically inert, non-film-forming character, the ability to protect colloid and compound many organic or inorganic compounds. In addition, acid, salt and heat are used continuously, so it is widely used.


application


in the pharmaceutical industry
PVP-K17 has excellent adhesive, non-film-forming, dispersion and thickening properties, and is widely used in the pharmaceutical industry.
Low molecular weight PVP-K17, a commonly used solvent vehicle, crystallization inhibitor and suspension stabilizer for injection and ophthalmic formulations such as PVP-K17.
Once used as a stabilizer non-film-forming agent for tablets, capsules and granules, oral suspensions on the skin of tablets, capsules and granules, as a specialist enzyme stabilizer for colorants and to improve bioavailability such as PVP-K17 medium molecular PVP-K .
high molecular PVP-K17 is highly effective skin as often used hydropylyzing agent such as oral and topical suspension, stabilizer consistency PVP-K17


cosmetic industry in
PVP-K17 is widely used in a wide range of hair care, skin care & oral care products. 
The products are particularly suitable for formulations where changes in viscosity and film forming properties are required.
PVP-K17 products are particularly suitable for hair styling products. For example, spray where medium molecular weights are critical in preferred viscosity applications such as PVP-K17. Higher molecular weight products such as PVP-K17 are the best option where high viscosity applications are required. 


PVP-K17 commonly follows
used in cosmetics 
* hair gels
* hair mousse
* liquid hair setting preparations
* sprays pump


industrial application
* Suspensant, spreader and emulsifier
* glass fiber
* detergent
* plastics and resin
* ink, not p and coating
*dies and printing Textile 
* Film and dhesive
*TV tube


PVP-K17 Physical properties:
PVP-K17 is available in white powder or aqueous solution.


Solubility: 
PVP-K17 is easily soluble in water, alcohol, amine and halohydrocarbon but insoluble in acetone and aether. 
PVP-K17 has good solubility, biocompatibility and physiologically inert, film-forming, colloid protect ability and compound ability of many organic or inorganic compounds. 
PVP-K17 is also acid, salt and heat resistant, so it is widely used.


PVP-K17 is available as white or milky white powder or colorless or slightly yellow transparent liquid. 
PVP-K17 can be dissolved in water and various organic solvents. 
PVP-K17 has hygroscopic, film-forming, complexing ability and physiological compatibility.


Application:
1.In Pharmaceutical Industry:


PVP-K17 (Pharmaceutical grade) is a kind of new excellent drug excipient. 
PVP-K17 is mainly used as binder for tablet and granule, co-solvent for injection, flow aid for capsule, dispersant for liquid medicine and pigment, stabilizer of enzyme and heat-sensitive drug, co-precipitant for poorly soluble drugs, lubricant and antitoxic excipient for eye medicines. . 
PVP-K17 has been used as an excipient in over a hundred drugs.
PVP-K17 has excellent adhesive, film-forming, dispersing and thickening properties and is widely used in the pharmaceutical industry.
PVP-K17 is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs.
Low molecular weight PVP-K17 is commonly used as a solubilizing agent, crystallization inhibitor and suspension stabilizer in injection and ophthalmic formulations.
-Medium Molecular such as PVP-K17 as a binder in tablets, capsules and granules, as a stabilizer in oral suspensions, film-forming agents, solubilizing agents, dispersing agent for pigments, enzyme stabilizer and increase bioavailability.
-High molecular PVP-K17, works as a highly effective binder. 
PVP-K17 is often used as a stabilizer, thickener, hydraulic agent, etc. in oral and topical suspensions. They are used as


2.In the Cosmetic Industry
PVP-K17 is widely applied in a wide range of hair care, skin care and oral care products. 
PVP-K17 is particularly suitable for formulations where viscosity modification and film forming properties are required. 
PVP-K17 is especially suitable for hair styling products.


Medium molecular weights such as PVP-K17 are preferred at critical points in viscosity such as spray.


-High molecular weight products such as PVP-K17 are a better choice when high viscosity is required in applications.


PVP-K17 is widely used in cosmetic products such as hair gel, hair mousses, liquid hair preparation preparations, pump sprays.


3.Other Industrial Applications of PVP K17 include:
- Suspension, dispersant and emulsifier
-Glass fiber
-Detergent
-Plastic and resin
-Ink
- Paint and coating
-Textile dyeing and printing
-Film Sticky
-TV tube


Description of povidone iodide:
PVP-K17 is a complex of PVP with iodine. 
PVP-K17 is available as a brown-red powder. 
PVP-K17 has very low toxicity but high efficiency.
PVP-K17 can effectively kill some bacteria, virus, fungus, mold and spore. 
PVP-K17 is an unirritated stable complex. 
PVP-K17 Iodine is completely water soluble, which makes it very easy to use.


PVP-K17, also known as iodopovidone, is used as an antiseptic that is applied heavily to the skin topically as a disinfectant before and after surgery. 
PVP-K17 is used as an antiseptic on patients' skin and disinfects doctors' hands. 
PVP-K17 is also important for treating minor cuts and wounds. 
PVP-K17 will be prepared in both powder and liquid form, PVP K17 powder and PVP K17 solutions.
PVP-K17 is stated to be one of the safest and most effective drugs on the WHO's essential medicine list.


PVP-K17 is also used in first aid for minor wounds, leeches, cuts, blisters, abrasions and burns.
PVP-K17 has the property of being slowly absorbed through the soft tissues. 
Therefore, PVP-K17 is preferred over other disinfectants in long surgeries. 
PVP-K17 is also effectively used in the treatment of bedsores and vaginitis.


PVP-K17 2.5% buffered solution can be used for the prevention of neonatal conjunctivitis. 
Also, PVP-K17 works in pleurodesis.


Special Notes: PVP-K17 may cause skin irritation. When used on large wounds, it can cause high sodium levels in blood and kidney problems. The above are considered side effects of PVP-K17.


PVP-K17 Benefits:


PVP-K17, Povidone Iodine has a broad spectrum germicidal effect
PVP-K17 is widely used to clean the skin and equipment before injection or surgery.
Anti-infection therapy is another use for PVP-K17.


In daily use, PVP-K17 disinfects family tableware and appliances,
PVP-K17 sterilizes and disinfects in the food industry.


PVP-K17 is one of the broad-spectrum disinfectants for both human and animal health. 


Other uses include:


1) Works as disinfectant aquatic and animals
2) PVP-K17, gynecological nursing products, aIt can be an antiseptic for oral care formulations etc.


Provide free recovery of infection (Advantages):
Protection and treatment of wounds against infection.
- Various germicidal effect against bacteria bacteria, fungi, protozoa and virus.
-PVP-K17 antiseptic is preferred universally.


 Application:
PVP-K17 is widely used worldwide as a local antiseptic for injection and instrumentation on skin and surgical brushes, and as a good remedy for infection. 
PVP-K17 also works as a germ killer for household utensils.


In addition, PVP-K17 acts as a good germicidal in the food industry, breed aquaculture industry and animal disease prevention. 
PVP-K17 has become the 1st iodine-containing disinfector chosen for medical treatment, health protection and epidemic prevention in developed countries. 


PVP-K17 Application:
1)PVP-K17 is a broad spectrum substance.
2)PVP-K17 can be used as a skin and equipment disinfectant before injection or surgery.
3)PVP-K17, oral, gynecological, surgical, skin, etc.
 PVP-K17 can be used as an anti-infection treatment for
4) PVP-K17 can also be used as disinfectants to family tableware and appliances.
5)PVP-K17 can be used such as sterilizing PVP-K17, disinfecting in food industry, aquaculture, preventing animal diseases etc.


In field of cosmetic: 
PVP-K17 can be used as filming-agent, viscosity-enhancement agent, lubricator and adhesive. They are the key component of hair sprays, mousse gels and lotions, hair-drying reagent and shampoo in hair-care products and the key component of lip-stick, sunscreen and lotions in skin-care products and also that of eye makeup, deodorant and dentifrice etc.


In field of pharmaceutical: 
PVP-K17 is a new and excellent pharmaceutical excipient. 
PVP-K17 is mainly used as binder for tablet dissolving assistant for injection, flow assistant for capsule, dispersant for liquid, medicine and stain, stabilizer for enzyme and heat sensitive drug, coprecipitant for poorly soluble drugs, lubricator and antitoxic assistant for eye drug.


In field of other utilities: 
Paint and coating, plastics and resin adhesive, glass fiber, film, ink, TV tube,detergent, biocide, tabulating assistant, textile dyeing and printing, etc.


PVP-K17 exists as powder or aqueous solution. 
PVP-K17 can dissolve in water and variety of organic solvent. 
PVP-K17 is used in paints, coatings, inks, textile dying and printing.


PVP-K17 products possess excellent adhesive,film-forming,dispersing and thickening properties,which are widely used in the pharmaceutical industry.They are one of the three main  accessory products recognized & approved worldwide.


General Summarization:
Low molecular weight PVP-K17 ,for use as a solubilizing agent,crystallization inhibitor and suspension stabilizer in injectables and ophthalmic formulations.Such as PVP-K17.Medium Molecular PVP-K17 for use as binder in tablets,capsules and granulers,as a stabilizer for oral suspensions,film-forming agent,soluilizing agent,dispersant for pigments,as an enzyme stabilizer and to imrove bioavailability.e.g. PVP-K17.
High molecular PVP-K17 ,a highly effetive binder,for us as stabilizer in oral and topical suspensions, as a thickener,hydropilizing agent e.g.PVP-K17.


PVP-K17 is a homopolymer of vinylpyrrolidone in a white to milky white-colored powder form. This product has a K value of 15-19 and a total solids content of greater than 95%. 
PVP-K17 is most commonly used as a suspending, dispersing, and emulsifying agent in paint, coating, adhesive, ink, and textile dyeing and printing applications.


PVP-K17, also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.


Uses
Medical


Structure of povidone-iodine complex, a common antiseptic.
PVP-K17 was used as a plasma volume expander for trauma victims after the 1950s. 
PVP-K17 is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.


PVP-K17 is used as a binder in many pharmaceutical tablets; PVP-K17 simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown).


PVP-K17 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs.
PVP-K17 is known under the trade names Pyodine and Betadine, among a plethora of others.


PVP-K17 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.


PVP-K17  is used in some contact lenses and their packaging solutions. 
PVP-K17 reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Examples of this use include Bausch & Lomb's Ultra contact lenses with MoistureSeal Technology and Air Optix contact lens packaging solution (as an ingredient called "copolymer 845").


PVP-K17 is used as a lubricant in some eye drops, e.g. Bausch & Lomb's Soothe.


Technical
PVP-K17 is also used in many technical applications:


PVP-K17 as an adhesive in glue stick and hot-melt adhesives
PVP-K17 as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and PVP-K17 in the chemical-mechanical planarization process
PVP-K17 as an emulsifier and disintegrant for solution polymerization
PVP-K17 to increase resolution in photoresists for cathode ray tubes (CRT)
PVP-K17 in aqueous metal quenching
PVP-K17 for production of membranes, such as dialysis and water purification filters
PVP-K17 as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating
PVP-K17 as a thickening agent in tooth whitening gels
PVP-K17 as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation
PVP-K17 as an additive to Doro's RNA extraction buffer
PVP-K17 as a liquid-phase dispersion enhancing agent in DOSY NMR
PVP-K17 as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly
PVP-K17 as a stabilizing agent in all inorganic solar cells


Other uses
PVP-K17 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.


PVP-K17 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes.
PVP-K17 has also been used in contact lens solutions and in steel-quenching solutions.
PVP-K17  is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.


As a food additive, PVP-K17 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. 
PVP-K17 is also used in the wine industry as a fining agent for white wine and some beers.


In molecular biology, PVP-K17 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. 
PVP-K17 is also exceptionally good at absorbing polyphenols during DNA purification. 
PVP-K17 are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR.


White or creamy white powder, odorless, non-toxic, non-irritating, easily dissolved in water, alcohol, amine and many other organic solvents. 
PVP-K17 is widely used in pharmaceutical fields, thanks to its excellent solubility, film formingcapability, chemical stability, physiogicalinertia and cementability.


Function
PVP-K17 products have excellent adhesive, film-forming, dispersion and thickening properties, widely used in the pharmaceutical industry.
Application
1. Cosmetics: PVP-K17 can be used as film-forming agent, viscosity increasing agent, lubricant and adhesive. In hair care products, it is the main ingredient of hair sprays, mousse, gels and lotions and solution, hair coloring reagent and shampoo. They can be used as an aid in skin care products, eye makeup, lipstick, deodorant, sunscreen and dentistry.
2. Pharmaceutical: PVP-K17 is an excellent new pharmaceutical stimulant. 
PVP-K17 is mainly used as binder for tablet, dissolving assistant for injection, flow assistant for capsule, dispersant for liquid drug and stain, stabilizer for enzyme and heat sensitive drug, coprecipitant for poorly soluble drugs, lubricant and antitoxic assistant for eye medicine. 
PVP-K17 works more excitingly than hundreds of drugs.
3. Other utilities: also paint and coating, plastic and resin, adhesives, glass fiber, Film, ink, TV tube, detergent, biocide, tabling, textile dyeing and printing, etc.
Polyvinylpyrrolidone (PVP-K17) has a low molecular weight. Suitable for use in styling formulas in liquid form, such as in spray form by giving natural styling (natural-hold) not stiff, used to catch curls.


Chemical formula
(C6H9NO)n
Molar mass        2.500 – 2.500.000 g·mol−1
Appearance        white to light yellow, hygroscopic, amorphous powder
Density        1.2 g/cm3
Melting point        150 to 180 °C (302 to 356 °F; 423 to 453 K) (glass temperature)


Key Specifications/Special Features:
Exists as white/milk white powder
Colorless/slight yellow transparent liquid
PVP-K17 can dissolve in water and a variety of organic solvents
PVP-K17 has good hygroscopicity, film-forming capability, complexing ability and physiological compatibility


Used as:
Suspensant, dispersant and emulsifier disinfect
Paint and coating printing ink
Textile and dyestuff building material
Paper making TV kinescope
Polymer ultra-filtration/micro-filtration membrane
Glass fiber


PVP-K17 are mainly used as film formers, but also as thickeners. The molecular weight determines the setting and adhesive properties of PVP polymers; the higher the molecular weight, the greater the setting. They are ideal for use in water-based applications where a high degree of clarity is required in the finished product (e.g. Gels).


•Water-soluble in high concentrations to form clear solutions
•Form clear, homogeneous films
•At low relative humidity the films are hard and brittle; at high relative humidity they are elastic and soft
•High water-absorption capacity
•Mixtures with polyacrylates, polyquats, salts, acids and bases are possible; high compatibility with many other cosmetic ingredients
•Nonionic, no neutralization required


General description
PVP-K17 can form complexes with phenolics and alkaloids. The complex formation allows removal of phenolics and alkaloids from plant samples, thereby inhibiting any modification of proteins by them and any hindrance they may cause in spectrophotometric determinations of protein content. 
PVP-K17 might also enhances the stability of enzymes.


Application
PVP-K17 has been used in the purification of glutamine synthetases from plant samples. 
PVP-K17 has been used to block the PVDF (polyvinylidene difluoride) membrane and to avoid nonspecific binding.


PVP-K17 is a nonionic water-soluble polymer and can be applied in a variety of fields-of-use owing to following advantageous characteristics.


Good solubility in water as well as various organic solvents
Good affinity to various polymers and resins
High hygroscopicity
Good film formation property
Good adhesiveness to various substrates
Good chelate / complex formation property


Applications


Adhesives        
water-activated (envelopes, stamps)
pressure-sensitive
glue sticks
bookbinding


Protective Colliods        
particle-size regulators
suspending agents
viscosity modifiers


Resin Compounds        
dye-receptivity/printability improvers
compatibilizers for heterogeneous resins
filler dispersants
wood plastic composites
anti-static agents


Films        
printability improvers
adhesiveness improvers
anchor coatings
anti-fogging agents
image receiving coatings
water soluble films


Textiles / Fibers        
dye stripping
dye-receptivity improvers
pigment dispersants
anti-fouling agents
hydrophilicity improvers
anti-static agents


Paper / Printing        
strength improvers
sizing agents
pigment dispersants
ink removal in recycling paper
ink jet paper


Coatings / Inks        
pigment /dye dispersants
viscosity modifiers
film levellers
anti-fogging coatings
anti-fouling coatings
ball-point inks


Laundry Detergants        
anti-redeposition agents
dye-transfer inhibitors
binders for tablet formulations
Metal Working        
metal quench bath


Oil / Gas Fields        
drilling fluid additives
fluid loss cotrol
gas hydrate preventors


Electrical        
black matrix for TV tube
binders for battery electrodes
nonwoven battery separator treatment


Ceramics        
binders for green sheets


Photography        
photo emulsion additives
colorant receptors


Cosmetic        
hair gel
hair spray
lip stic


IUPAC names
1-Ethenyl-2-pyrrolidinone homopolymer
1-Ethenyl-2-pyrrolidinone polymers
1-ethenylpyrrolidin-2-one
2-Pyrrolidinone, 1-ethenyl-, homopolymer
Agent I133
n-Vinylpyrrolidinone polymer
Poly(1-vinyl-2-pyrrolidinone)
Poly(N-vinyl-2-pyrrolidone)
Poly(vinylpolypyrrolidone)
Poly-1-vinyl-2-pyrrolidone
POLYVINYL PYRROLIDONE
Polyvinyl pyrrolidone
Polyvinylpyrrolidone
polyvinylpyrrolidone
Povidone
PVP
PVP K15


SYNONYMS:
Polyvinyl pyrrolidone
Povidone
PVP
PVP-K
PVP-K17
PVP-K25
Polyvinylpyrrolidine
PVP-K30
PVP K 30
PVP-K90
poly vinyl pyrrolidone
K-30
Crospovidone
Polyinylpyrrolidone
Polyvinglpyrrolidone

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