PVP K-30 (POLYVINYLPYRROLIDONE)

PVP K-30 (POLYVINYLPYRROLIDONE)

CAS Number: 9003-39-8 
EC Number: 618-363-4

Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.

SYNONYMS

PVP K-30; PVP K 30; pvpK 30; PVPK30; PVP, K, 30; pvp, k, 30; Polyvinylpyrrolidone; Poly, vinyl, pyrro, lidone; pvpk30; PVPK, 30; Poly(vinylpolypyrrolidone); Polyvinylpyrrolidone and Vinylpyrrolidone Copolymers (PVP); Hydrophilic Polymers; Hydrophobic Polymers; Materials Science; Poly(vinylpyrrolidinone) (PVP); Poly(vinylpyrrolidone); Poly(vinylpyrrolidone) (PVP) and Copolymers; Polymer Science, Polymers, Vinylpyridine and Vinypyrrolidone Polymers; Plasdone, PVP, Polyvidone, Povidone; 2-Pyrrolidinone, 1-ethenyl-, homopolymer (9003- 39-8); PVP, Povidone; PVPP, Crospovidone, Polyvidone; PVP K-30; PVP K 30; PVP K-30; PVP K 30; PVP K-30; PVP K 30; PNVP; Poly[1-(2-oxo-1- pyrrolidinyl)ethylen]; 1-Ethenyl-2-pyrrolidon homopolymer; 1-Vinyl-2-pyrrolidinon-Polymere; k25; k60; POP; PVP; k115; pvp2; pvp3; pvp4; pvp5; pvp6; Kollidon 25; Homopolymer of Vinylpyrrolidone; Polyvinylpyrrolidone; 1-Ethenyl-2-pyrrolidinone homopolymer; 1-Ethenyl-2-pyrrolidinone polymers; 1-Ethenyl-2-pyrrolidinone, homopolymer; 1-Vinyl-2-pyrrolidinone homopolymer; 1-Vinyl-2-pyrrolidinone polymer; PVP K-30; PVP K 30; PVP K-30; PVP K 30; PVP K-30; PVP K 30; 1-Vinyl-2-pyrrolidone polymer; 143 RP; 2-Pyrrolidinone, 1-ethenyl, homopolymer; 2-Pyrrolidinone, 1- vinyl-, polymers; 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with aluminum acetate; Agent AT 717; alpha-Hydro-omega-(p-iodobenzyl)poly(1-(2- oxo-1-pyrrolidinyl)ethylene)-(sup 131)I; alpha-Hydro-omega-(p-iodobenzyl)poly(1-(2-oxo-1-pyrrolidinyl)ethylene)-(sup 131)I.; (A small part of the iodine is the radioactive isotope, (sup 131)I.); Antaron P 804; AT 717; Caswell No. 681; CCRIS 3611; Crospovidone; Crospovidonum; PVP K-30; PVP K 30; PVP K-30; PVP K 30; PVP K-30; PVP K 30; Crospovidonum, [INN-Latin]; EPA Pesticide Chemical Code 079033; 1-vinylpyrrolidin-2-one homopolymer; Plasdone K29-32; Plasdone K29/32; Polyvinylpyrrolidone K 30; Polyvinylpyrrolidone K-29/32; Polyvinylpyrrolidone K30; Povidone K29-32; Povidone K29/32; PVP K-30; PVP K-30; PVP-K 30; Ganex P 804; Ganex p-804; Hemodesis; Hemodez; PVP K-30; PVP K 30; PVP K-30; PVP K 30; PVP K-30; PVP K 30; HSDB 205; K 115 (polyamide); K 115 (VAN); K 15; K 25 (polymer); K 25 (VAN); K 30 (polymer); K 30 (VAN); K 60 (polymer); K 60 (VAN); K 90; Peviston; Plasdone; Plasdone 4; CAS Number: 9003-39-8 

PVP was used as a plasma volume expander for trauma victims after the 1950s. It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.

It is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown). PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others.

It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.

PVP is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Examples of this use include Bausch & Lomb's Ultra contact lenses with MoistureSeal Technology and Air Optix contact lens packaging solution (as an ingredient called "copolymer 845").

PVP is used as a lubricant in some eye drops, e.g. Bausch & Lomb's Soothe.

PVP is also used in many technical applications:
•    as an adhesive in glue stick and hot-melt adhesives.
•    as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process
•    as an emulsifier and disintegrant for solution polymerization
•    to increase resolution in photoresists for cathode ray tubes (CRT) 
•    in aqueous metal quenching
•    for production of membranes, such as dialysis and water purification filters
•    as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating
•    as a thickening agent in tooth whitening gels
•    as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation
•    as an additive to Doro's RNA extraction buffer
•    as a liquid-phase dispersion enhancing agent in DOSY NMR 
•    as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly
•    as a stabilizing agent in all inorganic solar cells

PVP K-30 is a hygroscopic, amorphous polyvinylpyrrolidone. Used in industrial, specialty and imaging coatings & paints and as a media component in digital ink jet-printing. Oers high polarity, dispersancy, hydrophilicity, adhesion, cohesivity and high glass transition temperature. PVP K-30 can be plasticized with water and most common organic plasticizers. They are linear nonionic polymers thar are soluble in water and organi solvents and are pH stable. PVP K-30 forms hard glossy transparent lms and have adhesive, cohesive and dispersive properties.
PVP K-30 100% Powder is soluble in water and many organic solvents and it forms hard, transparent, glossy lm. PVP is compatible with most
inorganic salts and many resins. PVP stabilizes emulsions, dispersions and suspensions. While PVP is used as a lm former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-30 100% Powder appears as a white powder.

Applications
Adhesives, ceramics, glass (bers), coating/inks, electronic appliations, lithography and photography, bers and textiles, membranes, metallurgy, paper, polymerizations, water and waste teratment, and hygiene.

Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer Nvinylpyrrolidone: PVP was used as a plasma volume expander for trauma victims after the 1950s.

Technical 

PVP is also used in many technical applications: as an adhesive in glue stick and hot-melt adhesivesas a special additive for batteries, ceramics, berglass, inks, and inkjet paper, and in the chemical-mechanical planarization process as an emulsier and disintegrant for solution polymerization to increase resolution in photoresists for cathode ray tubes (CRT) in aqueous metal quenching for production of membranes, such as dialysis and water purication lters as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating as a thickening agent in tooth whitening gels.

Other uses 

PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as oldstyle postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a ning agent for white wine and some beers. In molecular biology, PVP can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buer. It is also exceptionally good at absorbing polyphenols during DNA purication. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP is useful for making an aqueous mounting medium.

Polyvinylpyrrolidone is abbreviated as PVP, and is the polymer of vinylpyrrolidone. According to the dierent degree of polymerization, it is further classied into soluble PVP and insoluble PVPP (polyvinyl polypyrrolidone). Molecular weight of the soluble PVP is 8,000 to 10,000.The soluble PVP can be used as a precipitating agent which can be settle down through its action with polyphenols. Using this method, it is easily to have residual PVP in the alcohol. Due to the savings eect of PVP inside the human body, the World Health Organization doesn't recommend to apply this substance. 

In recent years, the use of soluble PVP has been rare. Insoluble PVPP system had began to be used in the beer industry since the early 1960s. It has a relative molecule weight greater than the relative mass greater than 700,000. It is a insoluble polymer derived from the further cross-linking and polymerization of PVP and can be used as an adsorbent of polyphenols with a good efficacy. 

Polyvinylpyrrolidone PVP is one of the three major pharmaceutical new excipients and can be used as the co-solvent of tablets, granules, and injection, as the glidant of capsules, as the dispersant agent of liquid preparations and the colorant, as the stabilizer of enzyme and heat sensitive drug, as the co-precipitating agent of poorly soluble drugs, and as the detoxicant of ophthalmic drugs and lubricants.  It is industrially used as expanded polystyrene additive, as the gelling agents for suspension polymerization, stabilizer, and ber treating agents, paper processing aids, adhesives, and thickening agents.

Polyvinylpyrrolidone PVP and its copolymers CAP is an important raw material of cosmetics, mainly used for hair retaining agent. The lm it formed in the hair is elastic and shiny, and has excellent carding property as well as being free of dust. Adopting dierent category of resin can meet various kinds of relative humidity climatic conditions. Therefore, it is an indispensable raw material in styling hair cream, hair gel, and mousse. It can also be used for the cosmetics of skin moisturizing agents and the dispersants for grease based hair dying, also as foam stabilizers, and can improve the consistency of the shampoo.
General PVP (PVP K-30) Properties;
Linear nonionic polymer
• High polarity/proton acceptor
• Amphiphilic
• Compatible with a variety of resins and electrolytes
• Soluble in water and polar solvents, insoluble in esters,ethers, ketones and hydrocarbons
• Unsuitable for thermoplastic processing
• Hard, glossy, transparent, oxygen permeable films which adhere to a variety of substrates
• Hygroscopic
• Adhesive and cohesive properties
• Cross-linkable
• Physiologically inert 
Properties;

Molecular Weight:111.144 g/mol
Odor:ODORLESS
Appearance:White powder. Compatible with a wide range of hydrophilic and hydrophobic resins.
Color: Faintly yellow solid
Melting point ~165 °C (dec.)(lit.)
Boiling Point:90-93 deg C
density :1,69 g/cm3
Water Solubility :Soluble in water.
Sensitive :Hygroscopic
Stability:Stable. Incompatible with strong oxidizing agents. Light sensitive. Hygroscopic.
Specic Gravity: 1.1 - 1.3
pH: 3.0 - 7.0 (1:20 solution)

Inhalation: May cause irritation to the respiratory tract. Symptoms may include coughing, sore throat, labored breathing, and chest pain.
Ingestion: May cause irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.
Skin Contact: May cause irritation with redness and pain.
Eye Contact: May cause irritation, redness and pain.
Chronic Exposure: No information found.