PVP K 30

PVP(Polyvinylpyrrolidone)

CAS Number: 9003-39-8          
Formula: (C6H9NO)n          
Molecular Weight: (111,14)ng/mol

PVP K-30 is soluble in water and many organic solvents and PVP K-30 forms hard, transparent, glossy film. 
PVP is compatible with most inorganic salts and many resins. 

PVP stabilizes emulsions, dispersions and suspensions. 
While PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. 

Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. 
PVP K-30 appears as a white powder.

Polyvinylpyrrolidone (Polyvinylpyrrolidone) is the polymer compound of vinyl pyrrolidone. 
PVP K-30 is commercially referred to as PVP for short.
PVP K-30 is a water-soluble polyamide chemical.

There are 4 types of PVP.
The K number after PVP indicates the molecular weight of the chemical.

For example, PVP K-30 is specified as PVP K 15, PVP K 30, PVP K 60, PVP K 90.
Molecular weight is in Dalyan.

Due to PVP K-30 physiological structure, PVP K-30 is an inert chemical substance.
PVP K-30 has the ability to form complexes with inorganic salts.

PVP K30 (Polyvinylpyrrolidone), also called dye transfer inhibitors, are additives in laundry formulations that limit dye re-deposition on fabric during the wash cycle.

Agrimer PVP products are linear, non-ionic polymers that are soluble in water and many organic solvents.
They are pH stable and have adhesive, cohesive and bonding properties.

PVP K-30 unique ability to adsorb on a major active ingredient makes Agrimer PVP homopolymers the preferred choice for co-dispersants in many formulations.
Agrimer homopolymers have a high glass transition temperature.

Lower molecular weight (Mw) Agrimer polymers (Agrimer 15 and Agrimer 30) are suitable for applications where pollination is important, such as seed coatings and agglomeration.

Higher Mw Agrimer polymers (Agrimer 90 and Agrimer 120) can build formulation viscosity more quickly and provide excellent bonding and film-forming properties.
Higher Mw Agrimer polymers are also excellent carriers for pheromones and other attractants.

Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from N-vinylpyrrolidone monomer.

Polyvinylpyrrolidone (PVP) K 30 is a binder, dispersant, rheology modifier, film former, complexing agent.
BASF's Luvitec K 30 powder is a polyvinylpyrrolidone (PVP).

PVP K-30 exhibits film forming and solubilizing properties.
PVP K-30 is used in sticky sticks, wettable gums for postage stamps, envelopes and collection adhesives for bonds that can be broken and rebuilt several times.

Luvitec K 30 powder can also be used as a protective colloid and thickening agent in adhesive dispersions.
PVP K-30 acts as a film former and stabilizer.

PVP K-30 creates clear, hard, shiny and glossy films. 
PVP K-30 is a 30% hygroscopic and amorphous polyvinylpyrrolidone solution.

Provides a strong and firm grip.
PVP K-30 has excellent compatibility with acrylate thickeners.

Stabilizes foam, emulsions, dispersions and suspensions.
The PVP K-30 solution finds application in formulating hair care products such as sprays, mousses, gels, styling lotions/creams, colorants and new stylers.

Polyvinylpyrrolidone (PVP) is a water-soluble polymer obtained by polymerization of the monomer N-vinylpyrrolidone.
PVP K 30 is an inert, non-toxic, temperature resistant, pH stable, biocompatible, biodegradable polymer that helps encapsulate and feed both hydrophilic and lipophilic drugs.

These advantages make PVP a versatile excipient in formulation development from a wide range of conventional to new controlled delivery systems.
PVP has tunable properties and can be used as a support component for gene delivery, orthopedic implants and tissue engineering applications.

Based on different molecular weights and modified forms, PVP can lead to exceptionally beneficial properties with different chemical properties.
Vaccine copolymerization and other techniques help conjugate PVP with poorly soluble drugs that can inflate bioavailability and even introduce the desired swelling pathway for their control or sustained releases.

This review provides the chemistry, mechanical, physicochemical properties, evaluation parameters, moist preparation methods of PVP derivatives for design, from conventional to controlled systems for drug, gene and cosmetic application.
The past and growing interest in PVP has established PVP K-30 as a promising polymer for improving the property and performance of current generation pharmaceutical dosage forms.

Further, the review explores current patents, marketed products, identified and new and futuristic PVP approaches with scope for future development, characterization and use.
The discovery highlights the importance and role of PVP in the design of Povidone-iodine (PVP-I) and in clinical trials to evaluate therapeutic efficacy against COVID-19 in the current pandemic scenario.

Production of PVP K-30:
In order to obtain Raw Polyvinylpyrrolidone (PVP), polymerization method is applied.
In the recovery method, PVP K-30 is extracted with dilute acetic acid and 50% Ethyl Alcohol.

PVP K-30 is extracted after the polymerization reaction of 1-Vinyl-2-Prolidone purified with Hydrogen Peroxide in the presence of ammonia and some amines.

Benefits of PVP K-30:
Linear, nonionic polymer
High polarity / proton acceptor / π-bond
Amphiphilic
Physiologically inert
Compatible with a variety of active ingredients, resins and electrolytes
Improves the surfactant properties of certain surfactants
Forms tough glossy, transparent, oxygen-permeable films
Forms films with water activity
Adhesive and cohesive properties
Can be cross linked

Application of PVP K-30:
PVP K-30 is used as a binder in many pharmaceutical tablets; When taken orally, PVP K-30 simply passes through the body.
PVP is also used in many technical applications: as an adhesive in stick adhesives and hot melt adhesives.

Apart from that, PVP K-30 is also used as a thinning agent for white wine or some beers in the wine industry.
Other references state that polyvinyl pyrrolidone and PVP K-30 derivatives are of purely mineral synthetic origin.
Therefore, PVP K-30 use in production should not be a problem for vegans.

Usage Areas of PVP K-30:  
Among the polyvinylpyrrolidone PVP usage areas, the most common sector is medicine and cosmetics. 
PVP K-30 form is used in the cosmetics industry. 
The purpose of using PVP K-30 in the cosmetics industry is PVP K-30 ability to form a dispersing agent, a hard and at the same time bright transparent film.

Among the polyvinylpyrrolidone PVP usage areas, the most common sector is the pharmaceutical and cosmetics field.
PVP K-30 form is used in the cosmetics industry.

The purpose of using PVP K-30 in the cosmetics industry is PVP K-30 ability to form a dispersing agent, a hard and at the same time bright transparent film.
In the adhesive industry, in the manufacture of pressure sensitive adhesives, as an emery stone binder, as a viscosity modifier in the manufacture of ceramic-type products prepared at high temperatures.

PVP K-30 is used in the manufacture of adhesives used to bond rubber to metal.
PVP K-30 is used as a protective colloid and leveling agent in digital printing coating materials, ballpoint inks and emulsion polymers.

In the electronics industry, PVP K-30 is used as a binder in cathode ray tubes, printed circuits and storage batteries.
PVP K-30 is used to disperse titanium dioxide used in the textile industry.

PVP K-30 is used in the manufacture of the coating component used on the surface of aluminum, copper, zinc and nickel metals in the coating industry.
PVP K-30 is an excipient used to disperse and suspend drugs in pharmaceutical products.

PVP K30 is used in the production of pills used to relieve the common cold.
In addition, in this application, Polyvinyl Alcohol is used as a binder and with Xanthan Gum as a thickening agent.

Polyvinylprolidon PVP K is used as the adhesive chemical for transdermal systems.
PVPs act as binders and preservatives for enzymes.

PVP K-30 is used as a binder in the production of tablets used in the dishwasher.
PVP K-30 is used as a binder for tablets and capsules.

PVP K-30 is used as a binder and complexing agent in agricultural applications such as plant protection, seed treatment and coating.
PVP K-30 is used as a thickening agent in teeth whitening gels.

Polyvinylprolidon (PVP) is used in the production of membranes such as water and dialysis.
PVP K-30 is used as a stabilizing agent in the manufacture of all inorganic Solar cells.

PVP-K90 form is used as a binder in cement used in the construction industry.
As a food additive, PVP is a stabilizer and PVP K-30 E number is E1201.

PVP a is used in personal care products such as shampoos and toothpastes, paints, and adhesives that need to be moistened, such as old-fashioned postage stamps and envelopes.
Hydrogen Peroxide and Ammonia are used when producing medical grade PVP K90.
In this way, toxic contents are removed.

Adhesives - pressure sensitive and publicly refillable parts, packaging (indirect food food contact), metal adhesives, abrasives, abrasive, rubber metal adhesives and glue sticks.
Ceramics - high fire engineered products such as clay, pottery, porcelain, ceramic product, sample for ceramic media slurries and the like.

Glass and Glass Fibers - act as lubricant and coating material.
Coatings / lnks - digital printing coating, non-meter inks, emulsions / coatings / protective colloid for print starters and the leveling industry, pigment industry, water preservative coatings, protective coatings, paper coating, varnishes and varnishes.

Electronics Applications - storage batteries, printed circuits, cathode rays or tubes, metal salts in batteries or for their use, gold, nickel, copper plating plating, gel as a thickener for pools and as a product to prevent batteries from leaking. 
An expander in cadmium-type electrodes, optional in sintered powder plates.

Lithography and Photography - foil emulsions, etching coatings, casing, adhesive discs of lithographic plates, photographic and laser machines, microencapsulation, thermal recording, shielding, finisher shielding of lithographs, thermal transfer recording tapes and optical optical discs.
Fibers and Textiles - living in the classroom, dyeing and sightseeing, traffic coloring, eye painting and class, scrubbing, matte, sizing and finishing, clean oil, dirt class substance. 

PVP K-30 is widely used as a dye and to disperse titanium dioxide.
Membranes - macroporous, multi, desalination, gas selection, liquid ultrafiltration, hemodialysis, selectivity type membranes, hollow hollow fiber membranes.

Metallurgy - machining for both ferrous and non-ferrous metals, coating component to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum.
Paper - inorganic papers, cellulose papers, rag stock, peeling, coloring and forging processes, copy paper, printing paper and electrical insulation papers, paper adhesives.

Polymerizations - including acrylic monomers, unsaturated polyesters, olefins, PVC, styrene beads, substrate for graft polymerization, template in acrylic polymerization.
Water and Waste Treatment and Hygiene - in deodorants for clogging of reverse osmosis membranes, water treatment in fish hatchery ponds, removal of dye and waste water clarifier oil from waste water in papermaking, neutralization of irritating and toxic gases, filters in air conditioners.

Recommended Apps of PVP K-30:
Complex builder
Stabilizers / auxiliary distributors
Binders in dry/wet granulation and extrusion (dry compaction/fluid bed spray drying process)
Film forming agents / binders in seed coatings, dips and spills
Biological stabilization
Water binding / anti-perspiration properties
Solubility enhancers by co-precipitation or thermal extrusion
Paint binding agent

Resolution of PVP K-30:
Agrimer polymers are readily soluble in cold water with concentration limited only by viscosity.
PVP K-30 is possible to prepare free-flowing solutions of Agrimer polymers in concentrations up to 60% with only moderate effect on density.

About half a mole of water per monomer unit is associated with the polymer molecule in solution.
This is on the same order of magnitude as water of hydration reported for various proteins in the literature.

Agrimer polymers are also freely soluble in many organic solvents, including alcohols, nitroparaffins, and amines.
PVP K-30 is essentially insoluble in hydrocarbons, ethers, some chlorinated hydrocarbons, ketones and esters.

Dilute solutions of the Agrimer PVP polymer in hydrocarbons can be prepared using a cosolvent such as butanol, AgsolEx 1 solvent or nonylphenol.
Clear 3-5% Agrimer PVP polymer solutions in aliphatic hydrocarbons can be easily prepared by adding the hydrocarbon to a butyl alcohol solution of the polymer.

In some oil-based products PVP K-30 is useful to dissolve in an alkylphenol, for example octylor nonylphenol.
The alkylphenol is first heated to about 100 °C and the polymer is added slowly with stirring.
The temperature can then be increased to about 200 °C to accelerate dissolution.

Properties of PVP K-30:
Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers.
PVP K-30 is thought to be physiologically inert.

Applications take advantage of one or more of the inherent properties of the polymer, typically due to the pyrrolidone ring.
High polarity and consequent tendency to form complexes with hydrogen donors such as phenols and carboxylic acids, as well as with anionic dyes and inorganic salts.

Dispersion in which the components in a mixture are homogeneously dispersed using polyvinylpyrrolidone.
Hydrophilicity, where water solubility of PVP is the predominant property and is often a factor along with other properties valuable for many applications.

Adhesion takes advantage of the molecular weight PVP formulation in aqueous medium, which then evaporates enough water to form a solid product for the desired application.
Cohesiveness is where cohesive force is obtained by various dry mixing and granulation techniques.

Physical and Chemical Properties of PVP K-30:
PVP K-30 is in solid powder or crystal form in physical appearance.
PVP K-30 is a hygroscopic chemical.

Polyvinylpyrrolidone is a stable compound.
However, if PVP K-30 is heated together with Sodium Metasilicate and Trisodium Phosphate, PVP K-30 will precipitate.

PVP K-30 is a chemical that exhibits a high level of compatibility with many chemicals.
PVP K-30 Melting Point is around 165 °C.

Boiling Point is around 90-93 °C.
PVP (Polyvinylprolidon) density is 1.69 gr/cm³.

PVP K-30 has very good solubility in water and methyl alcohol.
PVP polymer is easily soluble in cold water, and the concentration is limited only by viscosity.

PVP K-30 is possible to prepare free-flowing PVP K-30 polymer solutions in concentrations up to 60% with only moderate effect on density.
PVP K-60 and K-90 polymer are commercially available as 45 percent and 20 percent aqueous solutions, respectively.

History of PVP K-30:
Structure of povidone-iodine complex, a common antiseptic.
PVP was used as a plasma volume expander for trauma victims after the 1950s.
PVP K-30 is not preferred as a volume expander because PVP K-30 can trigger histamine release and also interfere with blood grouping.

PVP K-30 is used as a binder in many pharmaceutical tablets; When taken orally, PVP K-30 simply passes through the body.
(However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who inject pharmaceutical tablets for oral consumption.

The long-term effects of crospovidone or povidone in the lung are unknown).
PVP added to iodine forms a complex called povidone-iodine, which has disinfectant properties.

This complex is used in a variety of products such as solutions, ointments, pessaries, liquid soaps and surgical scrubs.
PVP K-30 is known under the trade names Pyodine and Betadine, among others.

PVP K-30 is used in pleurodesis (fusion of the pleura due to persistent pleural effusions).
For this purpose, povidone-iodine is equally effective and safe as talc and may be preferred because of PVP K-30 easy availability and low cost.

PVP is used in some contact lenses and their packaging solutions.
PVP K-30 reduces friction, thereby acting as a lubricant or wetting agent built into the lens.
Examples of this use include Bausch & Lomb's Ultra contact lenses with MoistureSeal Technology and Air Optix contact lens packaging solution (as an ingredient called "copolymer 845").

Safety of PVP K-30:
The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses and is generally considered safe.

However, there have been documented cases of allergic reactions to PVP/povidone, particularly in relation to subcutaneous (applied under the skin) use and where PVP comes into contact with autologous serum (internal blood fluids) and mucous membranes.
After internal administration of povidone-iodine solution.

Identifiers of PVP K-30:
CAS Number: 9003-39-8          
Formula: (C6H9NO)n          
Molecular Weight: (111,14)ng/mol     
Density: 1.2 g/cm3          
Melting Point: 150-180 °C

Specification Values of PVP K-30:          
Appearance: Appropriate
Describing: Appropriate
PH value: 3.3
K-Value: 30.7
They are: %3.7
residue from burning: %0.07
Bullet: ppm< 10
aldehydes: %0.06
Hydraminler: ppm< 1

Other names of PVP K-30:
Polyvinyl Prolidone
polyvinylprolidone
Polyvinylprrolidone
povidone
PVP K-15
PVP K-30
PVP K-60
PVP K-90
polymer
Povidone-Iodine
Povidone-Iodine
poly[1-(2-oxo-1-pyrrolidinyl)ethylene]
Polyvinylpyrrolidone
polyvinylpyrrolidone
PVP

IUPAC names of PVP K-30:
1-ethenylpyrrolidin-2-one
PVP, Povidone
PVPP, Crospovidone, Polyvidone
PNVP
Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]
1-Ethenyl-2-pyrrolidone homopolymer
1-Vinyl-2-pyrrolidinone-Polymer

Trade name of PVP K-30:
PVP K30

Synonyms of PVP K-30:
2-Pyrrolidinone, 1-vinyl-, polymers (8CI)
1-Vinyl-2-pyrrolidinone polymer
1-Vinyl-2-pyrrolidone homopolymer
1-Vinyl-2-pyrrolidone polymer
Antitox Valve
Bolinan
Deltaspeed AF
Divergan F
Divergan RS
hemodez
hemodez
N-Vinyl-2-pyrrolidinone homopolymer
N-Vinyl-2-pyrrolidone polymer
N-Vinylbutyrolactam polymer
N-Vinylpyrrolidinone polymer
N-Vinylpyrrolidone homopolymer
N-Vinylpyrrolidone polymer
neohemods
PV 03 (vinyl pyrrolidone polymer)
Povidone / Polyvinylpyrrolidone (PVP)
polyvinylpyrrolidone
Povidone K-30
Povidone / PVP / POLYVINYL PYRROLIDONE