PVP K-90 (POLYVINYLPYRROLIDONE)

PVP K-90

CAS No.: 9003-39-8
EC No.: 201-800-4

Synonyms:
PVP K-90; PVP K 90; Polyvinylpyrrolidone 90; Polyvinylpyrrolidone; Polyvinylpyrrolidone; Vinylpyrrolidone Copolymers; pvp k 30; PVPK30; Polyvinylpyrrolidone; Hydrophilic Polymers; Hydrophobic Polymers; Materials Science; Poly(vinylpyrrolidinone) (PVP); Poly(vinylpyrrolidone); PVPK 30; PVP K90; Povidon K90; PVP K-90; Povidon K-90; polivinilprolidon; pvpk30; polyvınylprolidon; pvp90; 90; k90; polyvinilpirolidon; polyvınylprrpylıdone; Polyvinylpyrrolidone 90; Polyvinylpyrrolidone; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; Vinylpyrrolidone Copolymers; pvp k 30; PVPK30; Polyvinylpyrrolidone; Hydrophilic Polymers; Hydrophobic Polymers; Materials Science; K-30; POVIDONE; POP; POLYVINYLPYRROLIDONE K 25; POLYVINYLPYRROLIDONE K 30; POLYVINYLPYRROLIDONE K 90; POLYVINYLPYRROLIDONE K 60; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; POLYVINYLPYRROLIDONE-DIVERGAN RS; toxobin; vinisil; vinylpyrrolidinonepolymer; vinylpyrrolidonepolymer; PVP K30 USP24; PVP K120; K30 PVP K30; K 30 POVIDONE K 30 BP/USP; N-VINYL-2-PYRROLIDONE; 88-12-0; N-Vinylpyrrolidone; 1-Vinyl-2-pyrrolidone; 1-vinylpyrrolidin-2-one; N-Vinyl-2-pyrrolidinone; 2-Pyrrolidinone, 1-ethenyl-; POLYVINYLPYRROLIDONE; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; Vinylpyrrolidone; N-Vinylpyrrolidinone; 1-Vinyl-2-pyrrolidinone; 9003-39-8; 1-Vinylpyrrolidone; Pvpp; 1-ethenylpyrrolidin-2-one; Vinylbutyrolactam; Plasdone; Povidone; Vinylpyrrolidinone; Kollidon; Luviskol; Periston; Polyvidone; Protagent; Bolinan; 1-Vinylpyrrolidinone; Vinyl-2-pyrrolidone; Polyplasdone XL; Polyclar AT; V-Pyrol; Neocompensan; Hemodesis; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; Hemodez; Peviston; Plasmosan; Polygyl; Sauflon; Subtosan; Vinisil; 2-Pyrrolidinone, 1-vinyl-; Periston-n; Polyclar H; Polyclar L; Albigen A; Plasdone XL; Polyclar-AT; Peragal ST; Peregal ST; Poly(N-vinylpyrrolidone); 25249-54-1; Kollidon 17; Kollidon 25; Kollidon 30; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; 1-Ethenyl-2-pyrrolidinone; Plasdone No. 4; 1-Vinyl-2-pyrrolidinone, monomer; N-Vinyl pyrrolidone; Povidone (usp xix); Tolpovidone I-131; Antaron P 804; Poly(1-vinyl-2-pyrrolidone); K 25 (polymer); K 30 (polymer); K 60 (polymer); Vinylpyrrolidone polymer; Ganex p-804; PVP 40; K 115 (polyamide); Poly(vinylpyrrolidinone); Ganex P 804; Plasdone K 29-32; Poly-N-vinyl pyrrolidone; Vinylpyrrolidinone polymer; PVP K-90; PVP K 90; PVP K-90; PVP K 90; Poly(N-vinylbutyrolactam); N-Vinylpyrrolidone polymer; Poly(N-vinylpyrrolidinone); N-Vinylbutyrolactam polymer; Poly(1-vinylpyrrolidinone); N-Vinylpyrrolidinone polymer; Polyvinylpyrrolidine; PVP 1; PVP 2; PVP 3; PVP 4; PVP 5; PVP 6; PVP 7; NSC 10222; Poly(N-vinyl-2-pyrrolidone); PVP K 3; N-Vinyl-2-pyrrolidone polymer; 1-Vinyl-2-pyrrolidone polymer; MPK 90; Poly(N-vinyl-2-pyrrolidinone); PVP-K 30; PVP-K 60; PVP-K 90; N-Vinylpyrrolidone-2; Poly(1-vinyl-2-pyrrolidinone); Poly(1-(2-oxo-1-pyrrolidinyl)ethylene); PVP; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; 1-Vinyl-2-pyrrolidinone polymer; HSDB 7231; Poly-N-vinylpyrrolidone; UNII-76H9G81541; 1-Ethenyl-2-pyrrolidinone polymers; EINECS 201-800-4; 143 RP; AT 717; 1-vinyl-pyrrolidin-2-one; Polyvinylpyrrolidone K-30; Polyvinylpyrrolidone polymers; BRN 0110513; K 15; K 90; Poly(1-vinyl-2-pyrrolidinone) homopolymer; PVP-40; DTXSID2021440; CHEBI:82551; Povidone-iodine; MFCD00003197; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.1; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.2; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.3; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.4; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.5; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.6; Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.7; 2-Pyrrolidinone, polymers; 76H9G81541; DSSTox_CID_1440; DSSTox_RID_76160; 2-Pyrrolidinone, homopolymer; DSSTox_GSID_21440; Poly[1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl]; WLN: /T5NVTJ AY*1*/; 1-Vinyl-2-pyrrolidone(stabilized with 200ppm Ammonium hydroxide); PVP K-90; PVP K 90; PVP K-90; PVP K 90; CAS-88-12-0; Povidone K30; K 25; K 115; Caswell No. 681; Polyvinylpyrrolidone, average M.W. 3500, K12; Poly(1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl); N-Vinyl-2-pyrrolidone, 99%, stabilized with NaOH; Polyvinylpyrrolidone, average M.W. 50.000, K30; Polyvidonum [INN-Latin]; Polividona [INN-Spanish]; Polyvinylpyrrolidone K 90; Polyvinylpyrrolidone, average M.W. 8.000, K16-18; 2-Pyrrolidinone, polymers, compd. with aluminum acetate; Crospovidonum [INN-Latin]; N-Vinyl-2-pyrrolidone, 99%, stabilized with Kerobit(R); Polyvinylpyrrolidone, average M.W. 1.300.000, K85-95; CCRIS 3611; CCRIS 8581; HSDB 205; vinyl pyrrolidone; Polyvidone iodine; Poly[1-(2-oxo-1-pyrrolidinyl)-1, .alpha.-hydro-.omega.-[[4-(iodo-131I)phenyl]methyl]-; NCI-C60582; N-vinyl-pyrrolidone; PVP K-90; PVP K 90; PVP K-90; PVP K 90; K 115 (VAN); Povidone Impurity A; N -vinylpyrrolidinone; EPA Pesticide Chemical Code 079033; NSC 114022; NSC 142693; n-Vinyl-2-pyrolidone; 1-vinyl-2-pyrrolidon; N-vinylpyrrolidin-2-one; N-vinyl pyrrolidin-2-one; N-vinyl-pyrrolidin-2-one; PVP K3O; EC 201-800-4; poly (N-vinyl pyrrolidone); SCHEMBL10869; WLN: T5NVTJ A1U1; PVP K15; PVP K30; PVP-K30; KSC490C6R; Polyvinylpyrrolidone PVP K30; poly(1-vinylpyrrolidin-2-one); CHEMBL1878943; CTK3J0168; PVP - K-30 (Pharm Grade); KS-00000C7M; NSC10222; ZINC3590964; Tox21_202462; PVP K-90; PVP K 90; PVP K-90; PVP K 90; PVP K-90; PVP K 90; Tox21_300073; 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with aluminum acetate; ANW-41383; NSC-10222; NSC114022; NSC142693; NSC683040; N-Vinyl-2-pyrrolidone, optical grade; AKOS000119985; ACN-038204; CS-W020981; FG-0420; LS-2302; MCULE-3025814103; NSC-114022; PVP K-90; PVP K 90; PVP K-90; PVP K 90; NSC-142693; NSC-683040; VZ36857; alpha-Hydro-omega-(p-iodobenzyl)poly(1-(2-oxo-1-pyrrolidinyl)ethylene)-(sup 131)I; NCGC00166252-01; NCGC00166252-02; NCGC00166252-03; NCGC00254200-01; NCGC00260011-01; AK106255; K576; K90; SC-18112; SC-18133; LS-139036; 402-EP2311801A1; 402-EP2311802A1; 402-EP2311803A1; 402-EP2371814A1; FT-0608329; FT-0645144; FT-0655284; NS00002538; 3132-EP2269994A1; 3132-EP2270007A1; 3132-EP2272822A1; 3132-EP2289895A1; 3132-EP2292612A2; 3132-EP2298735A1; 3132-EP2301938A1; 3132-EP2314590A1; C19548; 15554-EP2305683A1; 15554-EP2311839A1; 15554-EP2314589A1; PVP K-90; PVP K 90; PVP K-90; PVP K 90; 15554-EP2316837A1; PVP K-90; PVP K 90; 29548-EP2279741A2; 29548-EP2284169A1; 29548-EP2287161A1; 29548-EP2287162A1; 29548-EP2289893A1; 29548-EP2298738A1; PVP K-90; PVP K 90; 29548-EP2311842A2; PVP K-90; PVP K 90; 34023-EP2295055A2; 34023-EP2295416A2; 34023-EP2298748A2; 34023-EP2298770A1; 34023-EP2311453A1; 121438-EP2272849A1; PVP K-90; PVP K 90; 121438-EP2298313A1; 121454-EP2284165A1; 121454-EP2298313A1; 121454-EP2375479A1; PVP K-90; PVP K 90; PVP K-90; PVP K 90; A817742; Q420628; SR-01000944531; J-015891; SR-01000944531-1; W-100417; 1-Vinyl-2-pyrrolidinone, SAJ first grade, >=99.0%; F8881-5579; 1-Vinyl-2-pyrrolidinone, contains sodium hydroxide as inhibitor, >=99%; 1-Vinyl-2-pyrrolidinone, Pharmaceutical Secondary Standard; Certified Reference Material; PVP K-90; PVP K 90; PVP K-90; PVP K 90; 1-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine); alpha-Hydro-omega-(p-iodobenzyl)poly(1-(2-oxo-1-pyrrolidinyl)ethylene)-(sup 131)I. (A small part of the iodine is the radioactive isotope, (sup 131)I.); Poly(1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl), alpha-hydro-omega-((4-(iodo-(sup 131)I)phenyl)methyl)-; PVP K-90; PVP K 90

Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and PVP K-90 (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. WHEN GIVEN PARENTERALLY, UNEXCRETED PARTICLES ARE PHAGOCYTIZED BY CELLS OF RETICULOENDOTHELIAL SYSTEM & DEPOSITED IN STORAGE SITES IN LIVER, SPLEEN, LUNG, BONE MARROW...In 12 nonpregnant women, total iodine, protein-bound iodine, inorganic iodine, and thyroxine values were measured in serum before and 15, 30, 45 or 60 minutes after a two-minute vaginal disinfection with povidone-iodine (Betadine). Only 15 minutes after application, serum iodine levels were raised and remained significantly elevated 30, 45 and 60 minutes after disinfection. Serum concentrations of total iodine and inorganic iodine were increased up to fivefold to 15-fold, respectively; during the relative short period of observation, thyroxine levels were not altered.The disposition of N-[14C]-vinyl-2-pyrrolidone has been studied in male Sprague-Dawley rats following a single iv injection. ...Up to 6 hr after dosing, the highest tissue concentrations of radioactivity were found in the liver and small intestines. By that time, about 19% of the dose had been excreted in bile, yet, by 12 hr, only about 0.4% had been excreted in feces while about 75% had been excreted in urine. Thus, there appeared to be substantial enterohepatic recirculation of biliary metabolites. Very small quantities of the administered material were excreted unchanged. In a single rat, 12% of the urinary radioactivity was present as acetic acid. Other metabolites were not identified.Following ingestion /1-vinyl-2-pyrrolidinone/ is mainly distributed in the liver and small intestine. It is partially excreted in the urine in an acetate form, but it is mostly (88%) combined with water-soluble acid compounds. Following iv injection, 14C-1-vinyl-2-pyrrolidinone was cleared from the blood with a half-life of about 2 hr. Unchanged /1-vinyl-2-pyrrolidinone/ accounted for <0.6% of the dose administered.The disposition of N-[14C-vinyl]-2-pyrrolidinone was studied in male Sprague-Dawley rats following a single iv injection. Plasma levels of the intact compound dropped rapidly within the first 6 hours after dosing... . Urinary excretion by 12 hours represented 74.9% of a 5 microCi dose while 18.7% was excreted into the bile by 6 hours. 14C-activity attributed to the intact compound was found to be <0.59% of the dose in the urine and <0.46% in the bile. Tissue distribution studies showed that the liver and small intestines and contents contained the highest accumulation of 14C-activity up to 6 hours after administration of N-[14C-vinyl]-2-pyrrolidinone. Urine analyses performed for metabolite elucidation indicated that 12% of the radioactivity dosed was incorporated into acetate and the major remaining portion in species which appeared to be water soluble acidic compounds.The toxic effects of vinylpyrrolidone /and/ vinylacetate (VP-VA) were examined in rats. Female Wistar-rats, under ether narcosis, were given endotracheally 0.5 mL of a standard solution of VP-VA (10 g in 15 mL of physiological sodium-chloride solution). Other rats received up to 7 times the 2 mL standard solution daily under the skin of the back; between 1.1 and 45.0 g/kg VP-VA were injected. The animals were sacrificed between 1 and 365 days following the application of the VP-VA solution. Tissues were stained and examined by electron microscopy. One to 2 days after endotracheal injection, the alveoli were closely packed with macrophages. Four to 6 months after the last injection, there was still VP-VA in the lungs with the attendent macrophages. Animals killed 1 yr after the last injection showed no VP-VA in the lungs. After sc injection, most of the VP-VA was stored in the spleen. There were occasional, large macrophages found in the interstitial tissue of the lung. During the 1 yr period of observation, there was no evidence of tumors or systemic disease.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.