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PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are synthetic, linear, random copolymers produced by the free-radical copolymerization of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers, with properties that can be precisely tailored by adjusting the VP/VA ratio.
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are functional copolymers developed to combine film strength with controlled water solubility.
Their balanced hydrophilic–hydrophobic structure provides flexible yet durable films and, combined with a well-established safety profile, has made PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers a cornerstone polymer in modern cosmetic and pharmaceutical product development.
CAS Number: 25086-89-9
EC Number: 621-403-3
Molecular Formula: C10H15NO3
Molecular Weight: 197.23
Synonyms: acetic acid ethenyl ester, 1-ethenyl-2-pyrrolidinone, 733045-73-3, Aceticacid,ethenylester,polymerwith1-ethenyl-2-pyrrolidinone, aceticacidethenylester,polymerwith1-ethenyl-2-pyrrolidinone, aceticacidethenylestercopolymerwith1-ethenyl-2-pyrrolidinone, aceticacidvinylester,polymerwith1-vinyl-2-pyrrolidinone, gantrons860, i535, i635, i735, 25086-89-9, Polectron 845, Luviskol VA 28I, Luviskol VA 37E, Luviskol VA 64, Kolima 10, Kolima 35, ethenyl acetate, 1-ethenylpyrrolidin-2-one, Gantron S 860, PVP-VA, Ganex E 535, GAF-S 630, Luviskol VA 281, Vinyl Pyrrolidone/Vinyl Acetate, N-vinylpyrrolidone/vinyl acetate, 1-vinylpyrrolidone vinyl acetate, BCP31918, NSC114023, NSC114024, NSC114025, NSC114026, AKOS015898247, NSC-114023, NSC-114024, NSC-114025, NSC-114026, 1-ethenylpyrrolidin-2-one, ethenyl acetate, ethenyl ethanoate, 1-ethenylpyrrolidin-2-one, FT-0659810, A817635, Luviskol VA 28 I, Luviskol VA 37 E, I 535, I 635, I 735, S 630, MFCD00134018, Luviskol VA-64, SCHEMBL29127, Copovidone (Technical Grade), vinylpyrrolidone/vinyl acetate
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are synthetic, linear random copolymers formed by the free-radical copolymerization of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers.
They typically appear as white powders or clear solutions and exhibit properties that can be precisely tailored by adjusting the VP/VA monomer ratio, allowing flexibility in performance across different applications.
Due to their excellent film-forming ability, adhesion, solubility in water and alcohols, and good mechanical strength, PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are widely used in cosmetic, personal care, and pharmaceutical formulations.
They provide strong yet flexible films, making them especially valuable as hair-fixing agents in hairsprays, gels, waxes, and styling creams, as well as binders and film formers in tablet coatings and controlled-release drug delivery systems.
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are generally regarded as non-irritating and non-sensitizing, with extensive toxicological data supporting their safe use at typical formulation levels.
Their balance of water solubility, film durability, and compatibility with a wide range of ingredients has made them a cornerstone polymer in modern cosmetic and pharmaceutical product development.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are a polymer formed by the copolymerization of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are a white powder with properties that can be adjusted through varying the monomer ratio, offering applications in multiple industries.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers has gained widespread attention due to its unique combination of properties.
Industry experts point out that understanding PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are crucial for grasping the development trends of multiple related industries.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are available as white powders or clear solutions in ethanol, isopropanol and water.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions.
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are synthetic, linear, random copolymers produced by the free-radical copolymerization of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers.
By varying the VP to VA ratio, typically within the range of 30:70 to 70:30, the physical, mechanical, and solubility properties of the polymer can be precisely adjusted.
This tunability allows manufacturers to design materials with specific film strength, flexibility, hydrophilicity, and adhesion characteristics to suit a wide variety of industrial and consumer applications.
In their raw form, PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are generally supplied as white to off-white free-flowing powders or as clear solutions in water, ethanol, or isopropanol.
Copolymers with higher vinyl pyrrolidone content exhibit greater water solubility and hygroscopicity, while higher vinyl acetate content enhances film hardness, water resistance, and durability.
This balance between hydrophilic and hydrophobic segments is one of the defining features of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers and underpins their broad functional versatility.
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are best known for their role as film-forming agents in cosmetic and personal care products, particularly in hair care formulations.
They are a key ingredient in hairsprays, styling gels, waxes, pomades, and creams, where they provide hold, shape retention, and humidity-responsive performance.
When applied, the polymer forms a thin, transparent film on the hair surface, imparting stiffness and control while remaining flexible enough to minimize flaking.
Their water solubility allows easy removal during washing, which historically contributed to their widespread adoption in early aerosol hairsprays and continues to support consumer preference today.
Beyond cosmetics, PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are extensively used in pharmaceutical applications.
They function as binders in tablet formulations for both direct compression and wet granulation processes, improving tablet cohesion and mechanical strength.
They are also employed as film-formers in tablet coatings, where they provide uniform coverage, good adhesion, elasticity, and controlled moisture permeability.
In advanced drug delivery systems, PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers may serve as matrix materials in controlled-release formulations, contributing to predictable drug release profiles and improved stability of active pharmaceutical ingredients.
Applications of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are widely applied across cosmetic, pharmaceutical, and industrial formulations due to their excellent film-forming, binding, and adhesion properties.
In personal care products, they are extensively used in hairsprays, styling gels, waxes, mascaras, and nail polishes to provide hold, flexibility, and long-lasting performance.
In pharmaceutical applications, PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers serve as tablet binders, coating agents, and matrix materials in controlled-release systems, improving mechanical strength and dosage stability.
They are also utilized in oral care products, coatings, inks, and adhesive formulations, where their solubility in water and alcohols, combined with good safety and compatibility, supports reliable performance in a wide range of formulations.
Pharmaceuticals:
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations.
In tableting, PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers can be used as a binder for direct compression and as a binder in wet granulation.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are often added to coating solutions as a film-forming agent.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are mainly used as water soluble and drying adhesive agent when making grain and pressing tablet directly.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers will be used in film coating and cover-taste agent.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers can prevent sugar coating from split and make bottom coating avoid dampness.
Cosmetics:
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers play a good role in film-former and hair-fixing agent.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers's hygroscopicity decreases with the increase of the proportion of vinylacetate in the molecular.
This property of PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are extremely useful as it works in hair sprays and hair-set lotion.
If PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are mixed with PVP K-30, the effect of hair-fixing would be changed a lot.
PVP/VA copolymers are extensively used as film-forming and fixing agents in hair care and cosmetic formulations.
They are a key component in hairsprays, styling gels, waxes, pomades, mousses, and styling creams, where they provide hold, shape retention, and humidity-responsive performance.
In color cosmetics, they are used in mascaras, eyeliners, foundations, and nail polishes to improve film integrity, adhesion, flexibility, and wear resistance.
In skin care products, PVP/VA copolymers help form a breathable film on the skin surface, contributing to moisture retention and improved sensory feel.
Oral Care Products:
PVP/VA copolymers are used in oral care formulations such as toothpastes and mouthwashes, where they act as film-formers and binders.
They improve product texture, stability, and adhesion to oral surfaces, contributing to prolonged contact of active ingredients.
Industrial and Specialty Formulations:
In industrial applications, PVP/VA copolymers are used as binders, thickeners, and film-forming agents in coatings, inks, and adhesives.
They provide good adhesion to a variety of substrates and help improve film strength and flexibility.
Their solubility in aqueous and alcoholic systems makes them suitable for environmentally friendly, low-VOC formulations.
Food and Nutraceutical Applications:
In certain regulated applications, PVP/VA copolymers may be used as binders or coating agents in dietary supplements and nutraceutical products, contributing to tablet integrity and controlled release, subject to applicable regulatory approvals.
Other industrial fields:
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers can be used in remoisten able adhesive and other adhesives for paper or viscosity-enhancing agent and protecting colloid for printing ink.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers 64 series can also act as emulsifying agent, protecting colloid for planting-protecting chemicals, Other dispersing systems and binder in coating.
Benefits of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers offer numerous benefits due to their balanced hydrophilic–hydrophobic structure and adaptable polymer composition.
They provide excellent film-forming ability, creating strong yet flexible films that deliver reliable hold, adhesion, and durability without excessive flaking.
Their solubility in water and alcohols allows easy formulation and removal, while adjustable VP/VA ratios enable precise control over film hardness, flexibility, and moisture sensitivity.
PVP/VA copolymers are compatible with a wide range of ingredients, exhibit good stability, and are generally regarded as non-irritating and non-sensitizing, making them suitable for cosmetic, pharmaceutical, and industrial applications where performance and safety are equally important.
Propeties of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers forms hard, glossy, water- removable lms.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers's viscosity, softening point and water sensitivity vary with VP/VA ratio.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers has good compatibility with many modiers and plasticisers that permit further variation of hygroscopicity and lm exibility.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are soluble in most common organic solvents and has good compatibility with aerosol spray propellants.
Production of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are produced by free-radical copolymerization of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers under controlled conditions.
The polymerization is typically carried out in solution, using solvents such as ethanol, isopropanol, or water, and initiated by suitable free-radical initiators.
By adjusting reaction parameters including monomer ratio, temperature, initiator concentration, and reaction time, manufacturers can precisely control PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers composition, molecular weight, and performance characteristics.
After polymerization, the product may be isolated as a solid powder through solvent removal and drying, or supplied directly as an aqueous or alcoholic solution, depending on the intended application.
Stability and Reactivity of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Chemical Stability:
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are chemically stable under normal ambient temperatures and recommended storage conditions.
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers does not undergo hazardous decomposition during routine handling, processing, or storage.
Reactivity:
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are generally inert under normal conditions of use.
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers does not react dangerously with most common formulation ingredients; however, like many organic polymers, it may degrade when exposed to strong oxidizing agents or extreme thermal conditions.
Conditions to Avoid:
Avoid excessive heat, open flames, prolonged exposure to high temperatures, and strong ultraviolet radiation, which may cause thermal degradation or discoloration.
Avoid excessive dust generation during handling of powdered forms.
Incompatible Materials:
Strong oxidizing agents, strong acids, and strong bases may cause degradation of the polymer backbone and should be avoided.
Hazardous Decomposition Products:
Under fire or extreme thermal decomposition conditions, PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers may release carbon monoxide (CO), carbon dioxide (CO₂), nitrogen oxides (NOx), and other irritating organic vapors.
Handling and Storage of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Safe Handling:
Handle PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers in accordance with good industrial hygiene and safety practices.
Avoid generating dust during handling of powder forms, as airborne particles may cause mild mechanical irritation.
Use controlled transfer methods and adequate ventilation to minimize dust exposure.
Hygiene Measures:
Wash hands and exposed skin thoroughly after handling.
Do not eat, drink, or smoke in areas where the product is handled or processed.
Remove contaminated clothing before entering clean areas.
Storage Requirements:
Store in tightly closed containers in a cool, dry, and well-ventilated area.
Protect from excessive heat, moisture, and direct sunlight to maintain product quality.
Packaging Integrity:
Keep packaging sealed when not in use to prevent moisture uptake and contamination.
Shelf Stability:
The product remains stable for extended periods when stored under recommended dry conditions; exposure to moisture may affect physical handling properties but not chemical identity.
First Aid Measures of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Inhalation:
Move the exposed person to fresh air.
If respiratory irritation, coughing, or discomfort persists, seek medical attention.
Symptoms are generally mild and related to mechanical dust irritation.
Skin Contact:
Wash affected skin with soap and water.
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are not expected to cause skin irritation or sensitization under normal conditions.
Seek medical advice if irritation persists.
Eye Contact:
Rinse eyes cautiously with plenty of clean water for several minutes, holding eyelids open.
Remove contact lenses if present and easy to do.
Mechanical irritation or redness may occur.
Seek medical attention if discomfort continues.
Ingestion:
Rinse mouth with water.
Ingestion of small quantities is not expected to cause harm.
Do not induce vomiting.
Seek medical attention if large amounts are ingested or if gastrointestinal discomfort occurs.
Firefighting Measures of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Flammability:
PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers are combustible solids but do not readily ignite under normal conditions.
Suitable Extinguishing Media:
Use water spray, foam, dry chemical powder, or carbon dioxide (CO₂) appropriate for surrounding materials.
Hazardous Combustion Products:
Combustion or thermal decomposition may produce carbon oxides, nitrogen oxides, and irritating organic fumes.
Special Protective Equipment for Firefighters:
Firefighters should wear self-contained breathing apparatus (SCBA) and full protective gear to avoid inhalation of decomposition products.
Specific Hazards:
Dust accumulation may contribute to reduced visibility during firefighting operations; avoid dispersing dust with high-pressure water streams.
Accidental Release Measures of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Personal Precautions:
Avoid breathing dust.
Ensure adequate ventilation and use appropriate personal protective equipment.
Prevent formation of airborne dust clouds.
Environmental Precautions:
PVP/VA Vinylpyrrolidone/Vinyl acetate copolymers are not expected to pose significant environmental hazards.
Prevent uncontrolled release into drains or waterways as a precaution.
Cleanup Methods:
Collect spilled material using sweeping, vacuuming with HEPA-filter equipment, or other methods that minimize dust generation.
Place collected material into suitable containers for disposal.
Do not use compressed air for cleanup.
Additional Advice:
After cleanup, wash contaminated surfaces to remove residual particles.
Dispose of waste in accordance with local regulations.
Exposure Controls and Personal Protective Equipment of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Engineering Controls:
Provide adequate general or local exhaust ventilation, particularly in areas where dust may be generated.
Enclosed handling systems are recommended for large-scale operations.
Respiratory Protection:
Not normally required under adequate ventilation.
Use a particulate respirator (e.g., N95 or P2) if dust concentrations exceed recommended limits.
Hand Protection:
Protective gloves are recommended for prolonged or repeated contact.
Eye Protection:
Safety glasses or goggles should be worn to prevent eye contact with airborne particles.
Skin and Body Protection:
Wear suitable protective clothing as required to prevent contamination.
Environmental Exposure Controls:
No special environmental control measures are required beyond standard dust containment and ventilation practices.
Identifiers of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
CAS Number: 25086-89-9
EC (EINECS) Number: 621-403-3
CBNumber: CB9295023
Molecular Formula: C₁₀H₁₅NO₃
Molecular Weight: 197.23 g/mol
Other(deleted CASRN): 1257874-67-1
FDA UNII: D9C330MD8B
MDL: MFCD00134018
CAS No: 25086-89-9
Chemical Name: Poly(1-vinylpyrrolidone-co-vinyl acetate)
CBNumber: CB9295023
Molecular Formula: C10H15NO3
Molecular Weight: 197.23
MDL Number: MFCD00134018
EC Number: 621-403-3
Properties of PVP/VA Vinylpyrrolidone/Vinyl Acetate Copolymers:
Appearance: White to off-white powder or clear solution.
Odor: Odorless or very faint odor.
Chemical Type: Synthetic organic copolymer.
Polymer Structure: Linear, random copolymer.
Solubility: Soluble in water, ethanol, and isopropanol.
Hygroscopicity: Moderately hygroscopic.
pH (aqueous): Near neutral, grade dependent.
Viscosity: Variable, depends on molecular weight and concentration.
Film-Forming: Forms clear, flexible films.
Adhesion: Good adhesion to hair, skin, and solid surfaces.
Mechanical Properties: Balanced strength and flexibility.
Density: 1.27 g/mL at 25 °C(lit.)
Tg: 108
refractive index: 1.4300 to 1.4380
Flash point: 72 °F
form: powder
color: White
Viscosity: 800.0 to 3000.0 mPa-s
InChI: InChI=1S/C6H9NO.C4H6O2/c1-2-7-5-3-4-6(7)8;1-3-6-4(2)5/h2H,1,3-5H2;3H,1H2,2H3
InChIKey: FYUWIEKAVLOHSE-UHFFFAOYSA-N
SMILES: C(N1CCCC1=O)=C.O(C=C)C(=O)C
LogP: 0.370 (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.95800 @ 25.00 °C.
Boiling Point: 217.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.132000 mmHg @ 25.00 °C. (est)
Flash Point: 72.00 °F. TCC ( 22.22 °C. )
logP (o/w): 0.370 (est)
