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PYLENE GLYCOL

Pylene glycol is a specific raw material used by manufacturers of green cosmetic products.
Pylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
Pylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.

CAS Number: 5343-92-0
EC Number: 226-285-3
Molecular Formula (Pylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol

1,2-Pentanediol, Pentane-1,2-diol, 1,2-Dihydroxypentane, 5343-92-0, Pylethylene Glycol, glycol, Glycol, Green Protector, 1,2-Dihydroxypentane, MFCD00010736, 1,a2-aPentanediol, EINECS 226-285-3, BRN 1719151, AI3-03317, NSC 513, 108340-61-0, ACMC-20mbh5, ACMC-1AXDB, EC 226-285-3, 1,2-Pentanediol, 96%, SCHEMBL62155, 3-01-00-02191 (Beilstein Handbook Reference), 1,2-Pentanediol, (2R)-, NSC513, WCVRQHFDJLLWFE-UHFFFAOYSA-, DTXSID10863522, NSC-513, AKOS009156977, AS-40006, SY032914, CS-0017222, FT-0606477, FT-0690841, P1178, 3-(2-NITRO-PHENYL)-ISOXAZOL-5-YLAMINE, 98484-EP2372017A1, A829586, Q3374899

Pylene glycol is a synthetic compound that belongs to the chemical group called 1,2 glycol.
Pylene glycol is a transparent liquid, slightly viscous, colorless, odorless and soluble in water as well as oil.

Pylene glycol is naturally derived from sugar cane.
Pylene glycol is used in many cosmetic products.
Pylene glycol is also referred to by the names 1,2- dihydroxypentane, 1,2-pentanediol, and pentane-1,2-diol.

Pylene glycol is a natural polyhydric alcohol and therefore has the ability to bind water.
This property can be used to moisturize the skin.

Skin is better hydrated, looks significantly brighter and feels better.
At the same time, Pylene glycol naturally helps inhibit the growth of microorganisms on the skin and can therefore be used as an alternative preservative.

Pylene glycol is soluble in water, acts as an extractant and solvent, is biodegradable, can be used in the pH range of 3-10, and is colorless and odorless.
Pylene glycol is made from natural sugar cane bagasse and is therefore ideal for natural cosmetics.

Pylene glycol is a specific raw material used by manufacturers of green cosmetic products.
The most important feature of this preservative is that Pylene glycol is obtained from agricultural products. For example, corn and sugar cane.
Pylene glycol is also commonly called Pentylene glycol.

Pylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
There are two alcohol groups attached to the 1st and 2nd carbon.

Pylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.
Pylene glycol is also obtained naturally from sugar cane.
Pylene glycol is also fat-soluble and used in many cosmetic products.

Pylene glycol is a natural diol derived from sugar cane bagasse's remaining waste, but a cheap synthetic analog also available in the market.
This multifunctional ingredient is a colorless, odorless, slightly viscous liquid that serves as a moisturizer, solubilizer, preservative, emulsion stabilizer, etc.

Pylene glycol is a well-known moisturizer due to the humectant properties of the molecule, proven scientifically by in-vivo studies.
Also, Pylene glycol is an excellent solubilizer, as Pylene glycol helps to solubilize many challenging ingredients, including fragrances.
Pylene glycol can also increase the clarity of translucent formulations like aqueous gels and toners.

Pylene glycol protects products from harmful bacteria and improves shelf-life, working synergistically with many preservatives, boosting their efficacy and thus helping to reduce their dose.
In addition, Pentane-1,2-diol stabilizes formulations, especially oil-in-water emulsions (as a co-emulsifier with an HLB value of 8.4), which helps reduce the particle size of emulsions, thus providing less coalescence and better stability.

This diol enhances the bioavailability of other ingredients (proven by ex-vivo study), boosting the activity of both lipophilic and hydrophilic actives.
Furthermore, Pylene glycol improves pigment distribution, makes whiter and shinier emulsions, promotes penetration into the skin, and improves the efficiency of cooling agents.

Incorporated in sun care applications, Pylene glycol enhances water resistance and the entire safety of the formula used even in SPF 50+ products.
Pylene glycol also can control the viscosity and texture of the final product.
In skin and hair care products and decorative cosmetics, Pylene glycol concentration can reach up to 5%.

Pylene glycol is used in formulations as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. 
Pylene glycol also helps moisturize and has a light, elegant feel to it. 

Pylene glycol will leave the skin soft and smooth.
Pylene glycol can help to solubilize and stabilize lipophilic ingredients in aqueous solutions.

Pylene glycol shows a broad spectrum antimicrobial activity against yeasts, moulds, and bacteria. 
Pylene glycol disturbs the integrity of microbial cell membranes, a mechanism of action that is unlikely to be affected by resistance. 

Being a non-ionic ingredient, the anti-microbial effect of Pylene glycol is largely pH-independent.
Pylene glycol can act as a standalone antimicrobial protection agent. 

In addition, Pylene glycol can be easily combined with other classical or non-classical antimicrobial agents, to boost their preservation effects. 
Pylene glycol a synthetic, low molecular weight solvent and skin-conditioning agent.
 
Pylene glycol is commonly used as a skin conditioning agent, due to Pylene glycol (1,2 pentanediol)’s ability to help the skin attract and retain moisture. 
As such, Pylene glycol falls into a category of skin care ingredients called humectants. 

Pylene glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative. 
Pylene glycol is both water and oil-soluble and Pylene glycol can have moisture-binding and Pylene glycol can have  antimicrobial properties.

Pylene glycol also has some anti microbial properties, which can make Pylene glycol a valuable addition to products that are susceptible to contamination of microorganisms. 
Pylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetic industry. 

Pylene glycol is used in sunscreens.
Pylene glycol is a skin moisturizer. 

Pylene glycol preserves moisture in the skin, helps to preserve elasticity and moisture of the skin. 
Pethylene glycol has an antimicrobial effect.
Pethylene glycol Lipid and dissolved lipophilic actives can be used in penetration enhancing creams and lotions. 

Pethylene glycol Hydrogenated phosphotidylcholine is a high viscosity base composed of protected lipids and glycerol.
Pylene glycol is an antimicrobial, chemically produced emulsifier. 

Pentilen Glycol has been included in the German Pharmaceutical Codex since 2009. 
However, Pylene glycol is not only approved in Germany, but Pylene glycol is also approved as a cosmetic active ingredient worldwide. 

Pylene glycol is initially based on the immature juice of sugar beets, while synthetic production is standard.
Pylene glycol is used in day and night creams. 

Pylene glycol is a complex system for paraben esters-free cosmetic and personal care products.
Pylene glycol is a multifunctional agent that has excellent efficacy as a biostatic and fungistatic agent.
Pylene glycol can reduce irritation and sensitivity and has a wide broad-spectrum antimicrobial effect.

Pylene glycol is an ingredient which is found naturally in some plants (such as sugar beets and corn cobs) but is most frequently lab-derived when used in cosmetics.
Pylene glycol is a humectant, meaning it binds well to water, making Pylene glycol a good hydrating agent and solvent to aid penetration of other ingredients.
Pylene glycol also helps improve the texture of skin care formulas and has mild preservative properties when used in amounts between 1-5%.

There have been some reports that Pylene glycol (along with other glycols) is a skin sensitizer; however, as with many ingredients, the amount and how it’s used are key.

Pylene glycol is a chemical compound commonly used in the cosmetics and personal care industry as a skincare and beauty product ingredient.
Pylene glycol is also known by its chemical formula C5H12O2.
Pylene glycol is a type of glycol, which is a class of organic compounds that contain multiple hydroxyl (OH) groups.

Pylene glycol proves multifunctional in skincare and cosmetic formulations, offering a spectrum of benefits.
With its hydrating properties, Pylene glycol serves as an effective moisturizer, aiding in maintaining skin moisture levels, particularly beneficial for individuals with dry or dehydrated skin.

Acting as a solvent, Pylene glycol ensures a consistent and uniform texture in products by dissolving other ingredients.
Pylene glycol antimicrobial properties contribute to its role as a preservative, preventing the growth of bacteria and fungi and enhancing Pylene glycol's longevity.

Recognized for Pylene glycol mild and non-irritating nature, Pylene glycol is considered suitable for sensitive skin.
Additionally, Pylene glycol facilitates the penetration of active ingredients, amplifying the efficacy of skincare formulations.
Overall, Pylene glycol is a versatile ingredient, addressing various aspects of skincare, from hydration and preservation to compatibility with different skin types.

Pylene glycol is generally recognized as safe for use in cosmetics and skincare products when used in accordance with regulations and guidelines.
However, as with any ingredient, individual reactions or sensitivities may vary, so it's essential to check Pylene glycol's ingredients list and perform a patch test if you have sensitive skin or allergies.

Uses of Pylene glycol:
Pylene glycol is used as an emulsion stabilizer, humectant, solvent and a broad-spectrum antimicrobial.
Pylene glycol improves texture of the product.

Pylene glycol has all the characteristics of a solvent.
Pylene glycol is not reactive and can dissolve many other compounds.

Pylene glycol is also known to have antimicrobial properties.

Pylene glycol offers a double advantage:
Pylene glycol protects the skin from harmful bacteria, which could otherwise cause body odor and acne problems on the skin.
Secondly, Pylene glycol protects the product from any microbial growth, so Pylene glycol  can show the same quality during its use and shelf life.

Skin care:
Due to the two -OH groups, Pylene glycol has a natural tendency to attract water.
Pylene glycol also retains water, which is especially helpful for dry skin.

Pylene glycol is used as a humectant and skin conditioning agent, for Pylene glycol ability to retain moisture.
Pylene glycol is used in moisturizer, baby sunscreen, around-eye cream, antiperspirant/deodorant, serums & essences, hand cream, anti-aging, facial moisturizer/treatment, detanning products, bath oil/salts/soak, body oil, body firming lotion, cuticle treatment, body wash/cleanser, tanning oil, recreational sunscreen

Hair care:
Pylene glycol is used in various hair care products such as hair treatment/serum, hair spray, hair styling aide, shampoo, detangler, beard care, shaving cream, beard oil, conditioner, hair color and bleaching, styling gel/lotion, mask, setting powder/spray

Decorative cosmetics:
Pylene glycol is used in cosmetics such as lipstick, concealer, eye shadow, foundation, CC cream, blush, lip balm, facial powder, bronzer/highlighter, lip gloss, BB cream, makeup primer, brow liner, lip liner, eye liner, lip plumper, lip balm, makeup remover

Uses Area of Pylene glycol:
Pylene glycol is used as a solvent in chemicals produced in the cosmetic industry to soften and smooth the skin.
Pylene glycol has a softening and smoothing effect in this area of use.

Pylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, 1,3-butylene glycol and Mono Pentylene glycol are also used as solvents.

This is because 1,3-butylene glycol and Mono Pentylene glycol do not have completely toxic effects.
Pylene glycol is used by combining anti-inflammatory hydrocortisone with Pentylene glycol to relieve minor skin irritation, temporary itching and inflammation.

Pylene glycol is used in the production of allergy medications.
Pylene glycol has antimicrobial properties because Pylene glycol is Dihydric Alcohol.

Pylene glycol helps prevent unwanted microorganisms due to Pylene glycol antimicrobial effect.
Pylene glycol is preferred in the production of quality cosmetic products because Pylene glycol allergic effects are very low.

Pylene glycol is used in the manufacture of daily skin care products due to Pylene glycol moisturizing effect on the skin.
By retaining water on the skin, Pylene glycol makes the skin more vibrant, smooth and plump.

Pylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetics industry. 
Pylene glycol has a softening and smoothing effect in this area of ​​use.

Pylene glycol is used together with steroidal hormones in the manufacture of dermatological products. 
In these applications, Pylene glycol and Mono Pentylene glycol are also used as solvents. 

This is because Pylene glycol and Mono Pentylene glycol do not have exactly the toxic effects.
Pylene glycol is used to relieve minor skin irritation, temporary itching and inflammation, by combining the anti-inflammatory hydrocortisone with pylenylene glycol.

Pylene glycol is used in the production of allergy medicines.
Pylene glycol has antimicrobial properties due to being dihydric alcohol.
Due to Pylene glycol antimicrobial effect, Pylene glycol helps to prevent unwanted microorganisms.

Pylene glycol is preferred in the manufacture of quality cosmetic products because of Pylene glycol very low allergic effects.
Pylene glycol is used in the manufacture of daily skin care products due to its moisturizing effect on the skin.
By keeping the water on the skin, Pylene glycol makes the skin more lively, smooth and full.

Applications of Pylene glycol:
Pylene glycol has a wide range of applications.
Intermediate finds applications in Initial product for chemical syntheses, Inks and coatings, Plasticizers and Solvent, Industrial chemicals.

Pylene glycol is used as a plasticizer in cellulose products and adhesives.
Pylene glycol is used as a brake fluid additive.

Pylene glycol reacts with 3,4-dihydro-2H-pyran to get 5-tetrahydropyran-2-yloxy-pentan-1-ol.
Pylene glycol is also used to prepare polyesters for emulsifying agents and resin intermediates.

Pylene glycol is used in ink, toner and colorant products.
In addition to this, Pylene glycol is used in brake fluid compositions.

Pylene glycol is used to produce materials made of polyester or polyurethane, for the manufacturing of monomers, for the manufacture of polyester polyols, polycarbonatedioles and acrylic monomers, for the production of delta valerolactone and for molecules that act as reactive diluents, for the production of halogenated substances and for the production of adhesives, putties and sealing compounds, cleaners and auxiliary agents.
Pylene glycol is used in the processes to produce hydrogen, hydrogen peroxide, sodium perborate and peroxyacetic acid and as an intermediate for pharmaceutical products.
Pylene glycol is used as an ingredient for the production of polymeric thickeners, plasticizers for polyvinyl chloride, sizing agents, surfactants, for starches and chemically modified starch for application in the paper, textile and food industry, for personal hygiene products like shampoo, creams, and for paints.

Benefits of Pylene glycol:
Pylene glycol naturally tends to attract water because Pylene glycol has two -OH groups.
Pylene glycol also retains water, which is especially beneficial for dry skin.

Pylene glycol is used as a humidifier due to its moisture retention capacity.
Pylene glycol has all the properties of a solvent.

Pylene glycol is non-reactive and can dissolve many other compounds.
As mentioned before, due to Pylene glycol ability to naturally retain moisture in the skin, Pylene glycol also nourishes the skin and hair.

Pylene glycol is also known to have antimicrobial properties.
Pylene glycol offers a double advantage – Pylene glycol protects the skin from harmful bacteria that can otherwise cause body odor and acne problems on the skin.

Secondly, Pylene glycol protects the product from microbial growth, so that Pylene glycol can maintain the same quality throughout its use and shelf life.
Pylene glycol is used in the formulations of creams, lotions, moisturizers, cleansers and other skin care products.

Pylene glycol offers several benefits when used in skincare and cosmetic products:

Moisturization:
Pylene glycol helps to hydrate the skin by retaining moisture, making Pylene glycol beneficial for individuals with dry or dehydrated skin.

Solvent:
Pylene glycol serves as a solvent for various cosmetic ingredients, ensuring that the product has a uniform texture and consistency.

Preservation:
Pylene glycol has antimicrobial properties, which help prevent the growth of harmful microorganisms like bacteria and fungi in cosmetic products, extending their shelf life.

Skin-Friendly:
Pylene glycol is known for being mild and non-irritating, making Pylene glycol suitable for sensitive skin types and reducing the risk of skin irritation or allergic reactions.

Enhanced Ingredient Penetration:
Pylene glycol can improve the absorption of other active ingredients into the skin, increasing the effectiveness of skincare formulations.

Peoduction of Pylene glycol:
Pylene glycol is produced synthetically from corn and sugar cane.

Origin of Pylene glycol:
Pylene glycol is based on by-products from manufacturing processes based on sugarcane residues and corn spindles.
However, Pylene glycol is manufactured in the lab as the consumption is relatively high.

Effect of Pylene glycol in the formulation:
antimicrobial
Emulsion stabilization
Moisturizer
Solvent

Physical And Chemical Properties of Pylene glycol:
Pylene glycol is a physically colorless oil-free liquid.
The density of Pylene glycol is 0.994 g/mol.

The melting point of Pylene glycol is -18 °C.
Pylene glycol is a stable chemical.

Pylene glycol should be stored at room temperature.
Pylene glycol is soluble in water.

Safety profile of Pylene glycol:
Pylene glycol does not have any evidence to suggest hazardous to health, toxicity, or carcinogenicity.
Pylene glycol has been found to cause mild irritation to the eyes and skin in skin types that are already sensitized or prone to irritation.

Health Effect of Pylene glycol:
Pylene glycol is a semi-synthetic component.
The starting raw materials are of natural origin, but are transformed into a different form than their original state using various processes under laboratory conditions.
These are raw materials obtained without using animal sources (propolis, honey, beeswax, lanolin, collagen, snail extract, milk, etc.).

Pylene glycol is a criterion that should be taken into consideration for those who want to use vegan products.
Studies have concluded that different effects can be seen on each skin type.

For this reason, the allergy/irritation effect may vary from person to person.
However, Pylene glycol may cause reactions such as stinging, tingling, itching, redness, irritation, skin flaking and swelling, especially in people with sensitive skin types.

Identifiers of Pylene glycol:
CAS Number: 5343-92-0
Chem/IUPAC Name: 2-heptanoyloxypentyl heptanoate
EINECS/ELINCS No: 226-285-3
COSING REF No: 58983

Molecular Formula (Pylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol
Chemical Name: 1,2-Pentanediol
CAS Number: 5343-92-0

Properties of Pylene glycol:
form: solution
mol wt: Mr ~1500
packaging: pkg of 10 × 4 mL
manufacturer/tradename: Roche
shipped in: wet ice
storage temp.: 2-8°C
SMILES string: C(CO)O
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Other Names of Pylene glycol:

IUPAC Names:
1,5-Pentanediol
1,5-pentanediol
Pentamethylene glycol
pentane,-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentanediol
 

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