PRODUCTS

PYRIDOXINE HYDROCHLORIDE

Pyridoxine hydrochloride is also used to treat nerve disorder and hereditary disorders like xanthurenic aciduria, cystathioninuria, hyperoxaluria and homocystinuria.
Pyridoxine hydrochloride finds application in cosmetics, food and feed additives.
Pyridoxine hydrochloride plays an important role in transporting protein Bsu1 and thiamine uptake.

CAS number: 58-56-0
EC number: 200-386-2
MDL Number: MFCD00012807
Molecular Formula: C8H11NO3.ClH / C8H12ClNO3
Molecular Weight: 205.64 g/mol

SYNONYMS:
Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride, Pyridoxinium chloride, Hexabione HCl, campoviton6, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride, paxadon, becilan, benadon, Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride, Pyridoxinium chloride, Hexabione HCl, campoviton6, PYRIDOXINE HYDROCHLORIDE, 58-56-0, Pyridoxine HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride, Pyridoxine chloride, Alestrol, Bonasanit, Hexavibex, Hexermin, Hexobion, Pyridipca, Becilan, Beesix, Benadon, Pydox, Campoviton 6, Hexa-Betalin, Hexabetalin, Aderoxin, Godabion, Paxadon, Pyridox, Aderoxine, Pyridoxin hydrochloride, Pyridoxinium chloride, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride, Aderomine hydrochloride, Hexabione hydrochloride, Hexa-Betalin (R), Pyridoxinum hydrochloricum, Rodex (R), Pyridoxol, hydrochloride, 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride, Pyridoxine monohydrochloride, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride, 3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride, NSC-36225, 5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride, 68Y4CF58BV, DTXSID1040792, CHEBI:30961, Pyridoxini hydrochloridum, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol;hydrochloride, DTXCID4010780, 4,5-Bis(hydroxymethyl)-3-hydroxy-2-methylpyridine hydrochloride, BONJESTA COMPONENT PYRIDOXINE HYDROCHLORIDE, DICLEGIS COMPONENT PYRIDOXINE HYDROCHLORIDE, BENDECTIN COMPONENT PYRIDOXINE HYDROCHLORIDE, DICLECTIN COMPONENT PYRIDOXINE HYDROCHLORIDE, Lyphomed, Vitalife, Pyridox-roche, Pyridox hcl, Vital foods, Pyridoxol Hcl, Comploment continus, Kent b6, PureVita Vitamin B6, Orovite comploment b6, Pyrid-10, Pyridid-20, PYRIDOXINE HCI, B-6 Pyridoxine HCL, RefChem:6489, 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol monohydrochloride, 200-386-2, NSC19613, Adermine hydrochloride, Bendectin, PN HCl, MFCD00012807, Pyridoxine (hydrochloride), (5-hydroxy-6-methylpyridine-3,4-diyl)dimethanol hydrochloride, Adermin hydrochloride, 8064-77-5, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride, Pyridoxine hydrogen chloride, Spondylonal, Pyridoxin hydrochloride (Vitamin B6 hydrochloride), Pyridoxol (hydrochloride);Vitamin B6 (hydrochloride), 4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride, Pyridoxine, hydrochloride, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride (1:1), Pyridoxinum hydrochloricum (Hungarian), SMR000674613, Hexa-betalin (TN), NSC36225, CCRIS 1903, component of Alestrol, HSDB 1212, Tex Six T.R., Clorhidrato de piridoxina, NCGC00164317-01, Vitamin B6-hydrochloride, EINECS 200-386-2, NSC 36225, Vitamin B6, hydrochloride, UNII-68Y4CF58BV, AI3-19016, Pyridoxine hydrochloride [JAN], 3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, chloride, Prestwick_925, Pyridoxine hydrochloride [USP:JAN], SCHEMBL42293, MLS001074329, MLS002153915, PYRIDOXINE HCL [VANDF], Pyridoxine hydrochloride, 98%, MSK1507A, orb1310114, SCHEMBL8992241, 3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride, CHEMBL1200756, HY-N0682R, HMS1569N08, HMS5081E16, HY-N0682, PXB92112, Tox21_302476, PYRIDOXINE HYDROCHLORIDE [MI], s3113, 3-Hydroxy-4,5-Dimethylol-Alpha-Pic, Pyridoxine hydrochloride (JP17/USP), pyridoxine hydrochloride (vitamin B6), PYRIDOXINE HYDROCHLORIDE [FCC], AKOS015891679, Pyridoxine (hydrochloride) (Standard), CCG-220623, CS-W020418, FP27320, PYRIDOXINE HYDROCHLORIDE [HSDB], 3,5-hydroxy-6-methyl-, hydrochloride, PYRIDOXINE HYDROCHLORIDE [MART.], PYRIDOXINE HYDROCHLORIDE [VANDF], NCGC00180946-01, NCGC00256911-01, PYRIDOXINE HYDROCHLORIDE [USP-RS], PYRIDOXINE HYDROCHLORIDE [WHO-DD], PYRIDOXINE HYDROCHLORIDE [WHO-IP], PYRIDOXINUM HYDROCHLORICUM [HPUS], AC-12024, AS-11752, ST007554, SY061587, WLN: T6NJ B1 CQ D1Q E1Q &GH, Pyridoxine hydrochloride, >=98% (HPLC), DB-053225, Pyridoxine hydrochloride, p.a., 98-102%, NS00075617, P0561, PYRIDOXINE HYDROCHLORIDE [GREEN BOOK], SW197042-3, TPN COMPONENT PYRIDOXINE HYDROCHLORIDE, PYRIDOXINE HYDROCHLORIDE [EP IMPURITY], PYRIDOXINE HYDROCHLORIDE [ORANGE BOOK], D02179, H12039, PYRIDOXINE HYDROCHLORIDE [EP MONOGRAPH], PYRIDOXINE HYDROCHLORIDE [USP MONOGRAPH], EN300-7548938, PYRIDOXINI HYDROCHLORIDUM [WHO-IP LATIN], VITAMIN B6 (AS PYRIDOXINE HYDROCHLORIDE), F547263, Pyridoxine Hydrochloride (B6), analytical standard, Pyridoxine hydrochloride, plant cell culture tested, SR-05000001644-4, Q26841284, F0001-2400, Pyridoxine hydrochloride, SAJ special grade, >=98.0%, Pyridoxine hydrochloride, Vetec(TM) reagent grade, 98%, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol;hydrochloride, Pyridoxine hydrochloride, meets USP testing specifications, Pyridoxine Hydrochloride 1.0 mg/ml in Methanol (as free base), 3-Hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine hydrochloride, Pyridoxine hydrochloride, certified reference material, TraceCERT(R), Pyridoxine hydrochloride, British Pharmacopoeia (BP) Reference Standard, Pyridoxine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Pyridoxine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Pyridoxine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Vitamin B6 hydrochloride;2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride, Pyridoxine hydrochloride, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant, Adermine hydrochloride, PN HCl, Pyridoxine hydrochloride, Pyridoxol hydrochloride, Vitamin B6 hydrochloride, Pyridoxine HCl, Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride, 3-Hydroxy-4,5-Dimethylol-Alpha-Pic; Pyridoxol Hydrochloride; Vitamin B6 Hydrochloride, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride, 3-Hydroxy-4,5-dimethylol-a-picoline hydrochloride, 3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride, 3-Hydroxy-4,5-dimethylol-α-picoline hydrochloride, 5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride, Adermin hydrochloride, Aderoxin, Becilan

Pyridoxine Hydrochloride is the stable hydrochloride salt of Vitamin B6.
Pyridoxine hydrochloride is naturally occurring Vitamin B6 exists as pyridoxine, pyridoxal, and pyridoxamine.
Among them, pyridoxine hydrochloride is the most stable and widely used form in nutrition, food, pharmaceuticals, and cosmetics.

In the body, Pyridoxine hydrochloride is converted into its active coenzyme form, Pyridoxal-5′-phosphate (PLP), which acts in over 100 enzymatic reactions.
Pyridoxine hydrochloride plays a vital role in metabolism of amino acids, carbohydrates, lipids, and neurotransmitters, making it an essential nutrient for humans, animals, and even certain industrial microbial processes.

Pyridoxine Hydrochloride is not just a vitamin supplement but a multifunctional compound bridging nutrition, medicine, cosmetics, and laboratory use — with broad benefits for metabolism, nerves, blood health, skin, and immunity.
Pyridoxine hydrochloride is the hydrochloride salt form of pyridoxine, a water-soluble form of Vitamin B₆.

In the body, Pyridoxine hydrochloride converts to the active coenzyme pyridoxal 5′-phosphate (PLP), essential in numerous enzymatic reactions including amino acid, neurotransmitter, and lipid metabolism.
Pyridoxine Hydrochloride is the hydrochloride salt form of pyridoxine, a water-soluble vitamin B.

Pyridoxine hydrochloride is converted into the active form, pyridoxal 5'-phosphate (PLP), an essential cofactor in many enzymatic activities including synthesis of amino acids, neurotransmitters, and sphingolipids.
Pyridoxine hydrochloride is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels.

Pyridoxine hydrochloride is a small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 3 approved and 2 investigational indications.
Pyridoxine Hydrochloride, known as vitamin B6 hydrochloride, is frequently employed in nutritional and biochemical research due to its importance in numerous metabolic processes.

Pyridoxine hydrochloride is a water-soluble vitamin that is a vital cofactor for enzymes catalyzing the metabolism of amino acids, lipids, and nucleic acids.
Pyridoxine hydrochloride is also essential for the study of homocysteine metabolism, as it is involved in converting homocysteine to cysteine.

Moreover, Pyridoxine Hydrochloride is applied in research on genetic disorders that affect its metabolism.
Pyridoxine hydrochloride is a salt of pyridoxine free base which is used to treat low levels of vitamin B6.
Pyridoxine hydrochloride is essential to maintain the health of nerves, skin and red blood cells.

Pyridoxine Hydrochloride contains salt form of vitamin B6 that restores vitamin B6 in the body and helps to treat its deficiency.
Pyridoxine hydrochloride is a salt of pyridoxine free base which is used to treat low levels of vitamin B6.

Pyridoxine hydrochloride is essential to maintain the health of nerves, skin and red blood cells.
Take Pyridoxine Hydrochloride as advised by the doctor.
In some cases, you may experience nausea, drowsiness, headache, mild tingling or numbness.

Most of these side effects of Pyridoxine Hydrochloride do not require medical attention and gradually resolve over time.
Pyridoxine Hydrochloride is used to treat vitamin B6 deficiency.
Vitamin B6 deficiency is caused due to malabsorption, protein-energy undernutrition, certain drugs or alcoholism.

The symptoms include cracked and sore lips, skin rashes, glossy tongue, weakened immune function, mood changes, low energy, tiredness, pain and tingling in hands and feet.
Pyridoxine hydrochloride, known as vitamin B6, is a vital nutrient that fulfills roles in numerous metabolic processes within the body.

Pyridoxine hydrochloride is indispensable for promoting normal growth and development, as well as ensuring the optimal functioning of the nervous system.
Pyridoxine hydrochloride can be obtained from various food sources.

Although the precise mechanism of action of pyridoxine hydrochloride remains incompletely elucidated, it is believed to operate through its interaction with specific proteins and enzymes within the body.
Pyridoxine Hydrochloride (syn: Vitamin B6) is the hydrochloride salt of Pyridoxine.

Pyridoxine hydrochloride is a pyridine derivative and is involved in a variety of enzymatic transformations and plays a role as an antioxidant in biological systems.
Pyridoxine was isolated and crystallized in 1938 by Samuel Lepkovsky.

It can be converted in animals into the enzymatically active form pyridoxal-5-phosphate.
Pyridoxal-5-phosphate is used in metabolic utilization and transformation of amino acids and is a cofactor in the synthesis of neurotransmitters and sphingolipids.

Pyridoxine Hydrochloride is soluble in water and DMSO but insoluble in ethanol.
Pyridoxine Hydrochloride is the hydrochloride salt form of pyridoxine, one of the six vitamers of Vitamin B6, a water-soluble vitamin essential in the human diet.

Commonly referred to as Vitamin B6, Pyridoxine Hydrochloride is available under various trade names including Hexa-Betalin, Nestrex, and Rodex.
Pyridoxine hydrochloride is crucial for a myriad of bodily functions, including amino acid metabolism, neurotransmitter synthesis, and hemoglobin production.

USES and APPLICATIONS of PYRIDOXINE HYDROCHLORIDE:
Pyridoxine hydrochloride is also used to treat nerve disorder and hereditary disorders like xanthurenic aciduria, cystathioninuria, hyperoxaluria and homocystinuria.
Pyridoxine hydrochloride finds application in cosmetics, food and feed additives.

Pyridoxine hydrochloride plays an important role in transporting protein Bsu1 and thiamine uptake.
Furthermore, Pyridoxine hydrochloride is also involved in various biochemical reactions.
Pyridoxine hydrochloride is also used to treat nerve disorder and hereditary disorders like xanthurenic aciduria, cystathioninuria, hyperoxaluria and homocystinuria.

Nutritional supplement — Pyridoxine hydrochloride addresses Vitamin B₆ deficiency, sideroblastic anemia, pyridoxine-dependent epilepsy, isoniazid-induced neuropathy, and certain metabolic or hereditary disorders.
Pyridoxine hydrochloride is employed in drug formulations (often combined with doxylamine for morning sickness), food and feed additives, cosmetic ingredients, and as reference standards in analytical chemistry.

Pyridoxine hydrochloride is used versatile for use in biology labs (cell culture, chemically defined media) and in analytical QC.
In studies, Pyridoxine Hydrochloride is used to understand its role in the synthesis of neurotransmitters, which are critical for normal brain function and development.

Pyridoxine hydrochloride finds application in cosmetics, food and feed additives.
Pyridoxine hydrochloride plays an important role in transporting protein Bsu1 and thiamine uptake.
Furthermore, Pyridoxine hydrochloride is also involved in various biochemical reactions.

Pyridoxine Hydrochloride is classified as a dietary supplement and is often found in multivitamin formulations, but it can also be prescribed as a standalone medication for therapeutic purposes.
Pyridoxine hydrochloride has gained significant attention over the years because of its wide range of therapeutic indications and low toxicity profile, making it a staple in both clinical and over-the-counter applications.

Pyridoxine Hydrochloride is primarily targeted for individuals with Vitamin B6 deficiency, either due to dietary insufficiencies or certain medical conditions such as alcoholism, liver disease, or chronic renal failure.

Additionally, Pyridoxine hydrochloride is utilized in the treatment of specific types of anemia and some metabolic disorders.
Research institutions around the globe are investigating the broader applications of Pyridoxine Hydrochloride, including its potential benefits in managing symptoms of premenstrual syndrome (PMS), depression, and even certain neurological conditions.

-Pharmaceuticals & Medicine uses of Pyridoxine hydrochloride:
Pyridoxine hydrochloride is used as a vitamin supplement in tablets, capsules, injectables.
Pyridoxine hydrochloride supports treatment of Vitamin B6 deficiency, sideroblastic anemia, metabolic disorders, and neurological issues.

Pyridoxine hydrochloride is often given with isoniazid, hydralazine, or penicillamine to prevent drug-induced neuropathy.
In combination drugs: with doxylamine (to treat morning sickness in pregnancy).

-Pyridoxine Hydrochloride is indicated in-
*Treatment and prevention of pyridoxine deficiency states.
*Sideroblastic anaemias.

*Seizures due to hereditary syndromes of pyridoxine deficiency or dependency in infants.
*Depression and other symptoms associated with premenstrual syndrome & the use of oral contraceptives.
*Prophylaxis of isoniazid-induced peripheral neuritis and for the treatment of acute isoniazid toxicity.

-Food & Nutrition uses of Pyridoxine hydrochloride:
Pyridoxine hydrochloride is widely used in fortified foods (cereals, baby food, dairy products, beverages).
Pyridoxine hydrochloride is essential component in multivitamins and sports nutrition products.
Pyridoxine hydrochloride is included in animal feed premixes to ensure healthy growth and metabolism in poultry, cattle, swine, and aquaculture.

-Cosmetics & Personal Care uses of Pyridoxine hydrochloride:
Pyridoxine hydrochloride is added to skincare and haircare products for its antioxidant, conditioning, and restorative effects.
Pyridoxine hydrochloride is used in anti-dandruff, anti-aging, and moisturizing products because Vitamin B6 helps with sebum regulation and skin barrier function.

-Biotechnology & Laboratory uses of Pyridoxine hydrochloride:
Pyridoxine hydrochloride is used in cell culture media as a required vitamin for cell growth.
Pyridoxine hydrochloride serves as a reference standard in analytical chemistry.

-Pyridoxine Hydrochloride is used in the management and treatment of Vitamin B6 deficiency.
The detailed uses of Pyridoxine Hydrochloride are as follows:

• Vitamin B6 Deficiency:
Pyridoxine Hydrochloride treats and prevents deficiency caused by poor diet, alcoholism, or certain medications.

• Anemia:
Pyridoxine Hydrochloride supports hemoglobin production and red blood cell formation.

• Morning Sickness in Pregnancy:
Pyridoxine Hydrochloride is often used to relieve nausea and vomiting during early pregnancy.

• Neurological Conditions:
Pyridoxine Hydrochloride is used in managing peripheral neuropathy and seizures.

KEY BENEFITS of PYRIDOXINE HYDROCHLORIDE:
***Metabolic Support
Pyridoxine hydrochloride acts as a coenzyme in metabolism of amino acids and neurotransmitters (serotonin, dopamine, GABA).
Pyridoxine hydrochloride helps convert glycogen to glucose, supporting energy production.

***Neurological Health
Pyridoxine hydrochloride supports normal nervous system function.
Contributes to the production of neurotransmitters, improving mood regulation and cognitive health.
Pyridoxine hydrochloride is often used to reduce symptoms of depression, anxiety, and PMS when related to Vitamin B6 deficiency.

***Hematological Benefits
Pyridoxine hydrochloride helps in hemoglobin synthesis and red blood cell formation.
Pyridoxine hydrochloride supports treatment of certain forms of anemia.

***Immune System Support
Pyridoxine hydrochloride boosts production of lymphocytes and antibodies.
Helps the body resist infections and maintain immune balance.

***Skin & Hair Benefits
Regulates sebaceous gland activity, beneficial in oily skin and acne.
Pyridoxine hydrochloride helps maintain healthy hair growth and prevents dandruff.

***Hormonal & Women’s Health
Pyridoxine hydrochloride plays a role in regulating hormones linked to PMS symptoms.
Pyridoxine hydrochloride is used in pregnancy supplementation (with medical supervision).

CHARACTERISTICS THAT MAKE PYRIDOXINE HYDROCHLORIDE POPULAR:
*Water-soluble → easy to use in supplements and drinks.
*Stable crystalline form → long shelf life compared to free pyridoxine.
*High bioavailability → readily absorbed and converted into active coenzyme form.
*Versatile applications → nutrition, medicine, cosmetics, biotechnology.

MEDICINAL BENEFITS of PYRIDOXINE HYDROCHLORIDE:
Pyridoxine Hydrochloride is used to treat vitamin B6 deficiency.
Pyridoxine hydrochloride restores vitamin B6 in the body and helps to treat its deficiency.
Also, Pyridoxine hydrochloride is used to treat peripheral neuritis (nerve damage) caused by isoniazid (a drug used to treat tuberculosis).

DIRECTIONS FOR USE PYRIDOXINE HYDROCHLORIDE:
Pyridoxine Hydrochloride can be taken with or without food.
It is recommended to take Pyridoxine Hydrochloride once daily at the same time each day or as advised by your doctor.
Swallow Pyridoxine Hydrochloride as a whole with a glass of water.
Do not crush, chew, or break it.

ALTERNATIVE PARENTS of PYRIDOXINE HYDROCHLORIDE:
*Methylpyridines
*Hydroxypyridines
*Heteroaromatic compounds
*Azacyclic compounds
*Primary alcohols
*Organopnictogen compounds
*Organonitrogen compounds
*Hydrochlorides
*Hydrocarbon derivatives
*Aromatic alcohols

SUBSTITUENTS of PYRIDOXINE HYDROCHLORIDE:
*Pyridoxine
*Hydroxypyridine
*Methylpyridine
*Heteroaromatic compound
*Azacycle
*Hydrocarbon derivative
*Organic oxygen compound
*Alcohol
*Hydrochloride
*Aromatic alcohol
*Organic nitrogen compound
*Primary alcohol
*Organooxygen compound
*Organonitrogen compound
*Organopnictogen compound
*Aromatic heteromonocyclic compound

SOLUBILITY of PYRIDOXINE HYDROCHLORIDE:
Pyridoxine hydrochloride is soluble in water and alcohol.
Pyridoxine hydrochloride is slightly soluble in acetone.
Pyridoxine hydrochloride is in soluble in ether and chloroform.

NOTES of PYRIDOXINE HYDROCHLORIDE:
Pyridoxine hydrochloride is light sensitive.
Pyridoxine hydrochloride is incompatible with bases and strong oxidizing agents.

BIOLOGICAL PROPERTIES & BENEFITS of PYRIDOXINE HYDROCHLORIDE:
Converts to PLP, a pivotal coenzyme in metabolism: amino acids, neurotransmitters (serotonin, dopamine, GABA), hemoglobin, sphingolipids, histamine, niacin production, and gene expression.
Pyridoxine hydrochloride is essential nutrient supporting red blood cell formation, nerve, skin, immune system function, and glucose metabolism.

Pyridoxine hydrochloride is a white powder.
Pyridoxine hydrochloride is the hydrochloride salt of pyridoxine.

Pyridoxine hydrochloride is a hydrochloride and a vitamin B6.
Pyridoxine hydrochloride contains a pyridoxine.

MECHANISM OF ACTION of PYRIDOXINE HYDROCHLORIDE:
The mechanism of action of Pyridoxine Hydrochloride centers around its role as a precursor to pyridoxal phosphate (PLP), the active form of Vitamin B6.

PLP serves as a coenzyme in a variety of biochemical processes, particularly those involving amino acids.
These reactions include transamination, decarboxylation, and racemization, which are vital for synthesizing neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA).

In addition to neurotransmitter synthesis, PLP is crucial for glycogenolysis, the process of breaking down glycogen into glucose-1-phosphate, thereby playing a significant role in glucose metabolism.
It also contributes to the synthesis of heme, an essential component of hemoglobin in red blood cells.

Furthermore, Pyridoxine Hydrochloride aids in the conversion of tryptophan to niacin, another vital B-vitamin.
When ingested, Pyridoxine Hydrochloride is absorbed in the small intestine and converted to PLP in the liver.

Pyridoxine hydrochloride's bioavailability may vary depending on factors such as age, nutritional status, and the presence of certain medical conditions.

Once converted to its active form, PLP participates in over 100 enzymatic reactions, underscoring the broad physiological impact of this essential nutrient.

HOW TO USE PYRIDOXINE HYDROCHLORIDE:
Pyridoxine Hydrochloride can be administered in several forms, including tablets, capsules, and liquid solutions.
Pyridoxine hydrochloride can also be given via intramuscular, intravenous, or subcutaneous injections, particularly in clinical settings where rapid correction of Vitamin B6 deficiency is needed.

For general supplementation, the recommended daily allowance (RDA) varies by age, sex, and physiological conditions such as pregnancy or lactation.
For adults, the typical dosage ranges from 1.3 to 2.0 milligrams per day.

In cases of deficiency or specific medical conditions, higher dosages may be prescribed under medical supervision.
For instance, individuals with pyridoxine-dependent epilepsy may require doses ranging from 30 to 600 mg per day.

The onset of action for oral Pyridoxine Hydrochloride is gradual, as it must first be absorbed and then converted to its active form.
Intravenous administration offers a more immediate effect, making Pyridoxine hydrochloride the preferred route in acute deficiency situations or emergency medical conditions.

Pyridoxine hydrochloride is crucial to follow the specific dosage and administration guidelines provided by a healthcare professional to ensure optimal efficacy and avoid potential adverse effects.

MECHANISM OF ACTION of PYRIDOXINE HYDROCHLORIDE:
Pyridoxine hydrochloride serves as a precursor of pyridoxal-phosphate (PLP), a coenzyme for amino acid and nucleic acid metabolism and neurotransmitter synthesis.

Pyridoxine hydrochloride, also known as pyridoxin or vitamin B6 hydrochloride, belongs to the class of organic compounds known as pyridoxines.
These are pyridoxal derivatives in which the carbaldehyde group at position 2 of the pyridoxal moiety is replaced by a hydroxymethyl group.
Based on a literature review a significant number of articles have been published on pyridoxine hydrochloride.

Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative.
Pyridoxine hydrochloride exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

PHYSICAL and CHEMICAL PROPERTIES of PYRIDOXINE HYDROCHLORIDE:
Melting Point: 159-162° C (lit.)
Physical State: powder
Color: white
Odor: odourless
Melting Point/Freezing Point: Melting point/range: 214 - 215 °C
Initial Boiling Point and Boiling Range: No data available
Flammability (solid, gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: No data available
Autoignition Temperature: No data available
Decomposition Temperature: 205 - 212 °C

pH: 2,3 - 3,2 at 50 g/l at 20 °C
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water Solubility: 159 g/l at 20 °C- completely soluble
Partition Coefficient: n-octanol/water: log Pow: -0,7 at 20 °C - Bioaccumulation is not expected.
Vapor Pressure: < 0,1 hPa at 25 °C - OECD Test Guideline 104
Density: 1,44 g/cm3 at 20 °C - OECD Test Guideline 109
Relative Density: 1,44 at 20 °C - OECD Test Guideline 109
Relative Vapor Density: No data available
Particle Characteristics: No data available

Explosive Properties: Not classified as explosive.
Oxidizing Properties: none
Other Safety Information: Surface tension 73,4 mN/m at 1g/l at 20 °C - OECD Test Guideline 115
CAS: 58-56-0
IUPAC Name: hydrogen 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol chloride
Molecular Formula: C8H12ClNO3
InChI Key: ZUFQODAHGAHPFQ-UHFFFAOYSA-N
SMILES: [H+].[Cl-].CC1=NC=C(CO)C(CO)=C1O
Molecular Weight (g/mol): 205.64
Synonym: hydrogen pyridoxine chloride

Assay (Titration ex Chloride): ≥98.5 to ≤101.5% (non-U.S. sourced material)
Appearance (Color): White to pale cream
Identification (FTIR): Conforms
Form: Powder or crystals or crystalline powder
Assay from Supplier's CofA: ≥98.5% (U.S. sourced material)
Comment: Material Sourced in the U.S. and in other countries
Melting Point: 200-210°C (non-U.S. sourced material)
Molecular Formula / Molecular Weight: C8H11NO3·HCl = 205.64
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
Condition to Avoid: Light Sensitive

CAS RN: 58-56-0
Reaxys Registry Number: 3632435
PubChem Substance ID: 87574736
Merck Index (14): 7982
MDL Number: MFCD00012807
logP: -0.95
pKa (Strongest Acidic): 9.4
pKa (Strongest Basic): 5.58
Physiological Charge: 0
Hydrogen Acceptor Count: 4
Hydrogen Donor Count: 3

Polar Surface Area: 73.58 Å²
Rotatable Bond Count: 2
Refractivity: 44.11 m³·mol⁻¹
Polarizability: 17.11 Å³
Number of Rings: 1
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Chemical Formula: C8H12ClNO3

IUPAC Name: 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
InChI Identifier: InChI=1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H;1H
InChI Key: ZUFQODAHGAHPFQ-UHFFFAOYSA-N
Isomeric SMILES: Cl.CC1=C(O)C(CO)=C(CO)C=N1
Average Molecular Weight: 205.639
Monoisotopic Molecular Weight: 205.050570962
Boiling Point: Not Available
Charge: Not Available
Density: Not Available
Experimental logP: -0.77
Experimental pKa: Not Available
Experimental Water Solubility: 220 mg/mL
Isoelectric Point: Not Available

Mass Composition: Not Available
Melting Point: Mp 206-208°
Optical Rotation: Not Available
CAS Number: 58-56-0
EC Number: 200-386-2
Molecular Weight: ca. 205.64 g/mol
Molecular Formula: C8H11NO3.ClH
C8H12ClNO3
Molecular Weight: 205.64 g/mol

Appearance: White to off-white crystalline powder
Odor: Odorless
pH (aqueous solution): Around 2.3–3.2 at 20 °C (50 g/L); other measurements around 3.2 (5% solution)
Melting Point: Approximately 214–215 °C; some sources note ~205 °C with decomposition
Solubility:
Water: ~159 g/L at 20 °C (fully soluble)
Slightly soluble in alcohol; insoluble in ether or chloroform; soluble in propylene glycol
Partition Coefficient (log P): About –0.7 at 20 °C; estimated value –1.098
Vapor Pressure: Less than 0.1 hPa at 25 °C

Density: Approx. 1.44 g/cm³ at 20 °C
Stability: Stable under recommended storage; light-sensitive, protect from light and moisture
Other: Not expected to bioaccumulate
CAS / EC: 58-56-0 / 200-386-2
Formula / MW: C₈H₁₁NO₃ · HCl / ~205.64 g/mol
Appearance: White/off-white powder, odorless
pH (solutions): ~2.3–3.2
Melting Pt.: ~214–215 °C
Solubility: Highly soluble in water, limited in alcohol; insoluble in ether
Log P: ~ –0.7 to –1.1
Vapor Pressure: <0.1 hPa at 25 °C

Density: ~1.44 g/cm³
Stability: Stable; light-sensitive
Uses: Dietary supplement, pharmaceuticals, lab reagent, analytical standard, feed additive
Biological Roles: Cofactor in multiple metabolic pathways; nerve, blood, skin, immune support
Molecular Weight: 205.64 g/mol
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 205.0505709 Da
Monoisotopic Mass: 205.0505709 Da
Topological Polar Surface Area: 73.6 Å²
Heavy Atom Count: 13

Formal Charge: 0
Complexity: 142
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Empirical Formula (Hill Notation): C8H11NO3 · HCl
CAS Number: 58-56-0

Molecular Weight: 205.64
Beilstein: 3632435
EC Number: 200-386-2
MDL Number: MFCD00012807
UNSPSC Code: 12352205
eCl@ss: 34058008
PubChem Substance ID: 24899059
NACRES: NA.55
Appearance: Powder
Physical State: Solid
Storage: Store at room temperature

FIRST AID MEASURES of PYRIDOXINE HYDROCHLORIDE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of PYRIDOXINE HYDROCHLORIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of PYRIDOXINE HYDROCHLORIDE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of PYRIDOXINE HYDROCHLORIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of PYRIDOXINE HYDROCHLORIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of PYRIDOXINE HYDROCHLORIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available