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PYRIDOXINE

CAS NUMBER: 65-23-6

EC NUMBER: 200-603-0

MOLECULAR FORMULA: C8H11NO3

MOLECULAR WEIGHT: 169.18

IUPAC NAME: 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol


Pyridoxine (vitamin B6) is used to prevent or treat low levels of vitamin B6 in people who do not get enough of the vitamin from their diets. 
Most people who eat a normal diet do not need extra vitamin B6. 
However, some conditions (such as alcoholism, liver disease, overactive thyroid, heart failure) or medications (such as isoniazid, cycloserine, hydralazine, penicillamine) can cause low levels of vitamin B6. 

Pyridoxine plays an important role in the body. 
Pyridoxineis needed to maintain the health of nerves, skin, and red blood cells.

Pyridoxine has been used to prevent or treat a certain nerve disorder (peripheral neuropathy) caused by certain medications (such as isoniazid). 
Pyridoxine has also been used to treat certain hereditary disorders (such as xanthurenic aciduria, hyperoxaluria, homocystinuria).

What is Pyridoxine?
Pyridoxine is vitamin B6. 

Vitamins occur naturally in foods such as:
- meat

-poultry

-nuts

-whole grains

-bananas

-avocados

Pyridoxine is important for many processes in the body.
Pyridoxine is used to treat or prevent vitamin B6 deficiency. 
Pyridoxine is also used to treat a certain type of anemia (lack of red blood cells). 

Pyridoxine injection is also used to treat some types of seizure in babies.
Pyridoxine taken by mouth (oral) is available without a prescription. 
Injectable pyridoxine must be given by a healthcare professional.

Pyridoxine, vitamin B6, is required by your body for utilization of energy in the foods you eat, production of red blood cells, and proper functioning of nerves. 
Pyridoxine is used to treat and prevent vitamin B6 deficiency resulting from poor diet, certain medications, and some medical conditions.

Pyridoxine, is a form of vitamin B6 found commonly in food and used as a dietary supplement. 
As a supplement Pyridoxine is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning.

Pyridoxine is used by mouth or by injection.
Pyridoxine is usually well tolerated.

Pyridoxine is in the vitamin B family of vitamins.
Pyridoxine is required by the body to metabolise amino acids, carbohydrates, and lipids.
Sources in the diet include fruit, vegetables, and grain

Medical Uses:
As a treatment (oral or injection), Pyridoxine is used to treat or prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects of isoniazid treatment and certain types of mushroom poisoning.
Isoniazid is an antibiotic used for the treatment of tuberculosis. 

Co-treatment with vitamin B6 alleviates the numbness.
Pyridoxine-dependent epilepsy is a type of rare infant epilepsy that does not improve with typical anti-seizure medications.
Pyridoxine in combination with doxylamine is used as a treatment for morning sickness in pregnant women.

Mechanism Of It:
Pyridoxine is in the vitamin B family of vitamins.
Pyridoxine is required by the body to make amino acids, carbohydrates, and lipids.
Sources in the diet include fruit, vegetables, and grain.
Pyridoxine is also required for muscle phosphorylase activity associated with glycogen metabolism.

Pyridoxine, also known as pyridoxine, is a water-soluble vitamin that your body needs for several functions.
Pyridoxine’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters.

Your body cannot produce Pyridoxine, so you must obtain it from foods or supplements.
Most people get enough Pyridoxine through their diet, but certain populations may be at risk for deficiency.
Consuming adequate amounts of Pyridoxine is important for optimal health and may even prevent and treat chronic diseases 

BENEFITS:

*Pyridoxine Improves Mood and Reduce Symptoms of Depression

*Pyridoxine Promotes Brain Health and Reduce Alzheimer’s Risk

*Pyridoxine Prevents and Treat Anemia by Aiding Hemoglobin Production

*Pyridoxine is Useful in Treating Symptoms of PMS

*Pyridoxine Helps Treat Nausea During Pregnancy

*Pyridoxine Prevents Clogged Arteries and Reduce Heart Disease Risk

*Pyridoxine Helps Prevent Cancer

*Pyridoxine Promotes Eye Health and Prevent Eye Diseases

*Pyridoxine Treats Inflammation Associated With Rheumatoid Arthritis


Pyridoxine is a vitamin used for preventing and treating low levels of pyridoxine (pyridoxine deficiency) and the "tired blood" (anemia) that may result. 
Pyridoxine is also used for heart disease; high cholesterol; reducing blood levels of homocysteine.

Pyridoxine, or pyridoxine, is a water-soluble vitamin found naturally in many foods, as well as added to foods and supplements. 
Pyridoxine is the active coenzyme form and most common measure of B6 blood levels in the body. 

Pyridoxine is a coenzyme that assists more than 100 enzymes to perform various functions, including the breakdown of proteins, carbohydrates, and fats; maintaining normal levels of homocysteine (since high levels can cause heart problems); 
Pyridoxine is supporting immune function and brain health. 

Food Sources:
Pyridoxine is found in a variety of animal and plant foods.
-Beef liver
-Tuna
-Salmon
-Fortified cereals
-Chickpeas
-Poultry
-Some vegetables and fruits, especially dark leafy greens, bananas, papayas, oranges, and cantaloupe

Pyridoxine is a hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. 
The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. 

Pyridoxine has a role as: 

-a cofactor, 

-a human metabolite, 

-a Saccharomyces cerevisiae metabolite, 

-an Escherichia coli metabolite

-a mouse metabolite

Pyridoxine is a monohydroxypyridine, a vitamin B6, a member of methylpyridines and a hydroxymethylpyridine.
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. 

As Pyridoxine's classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. 
While many plants and microorganisms are able to synthesize pyridoxine through endogenous biological processes, animals must obtain it through their diet. 

More specifically, Pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. 
Pyridoxine's important to note that Vitamin B6 is the collective term for a group of three related compounds, pyridoxine, pyridoxal, and pyridoxamine, and their phosphorylated derivatives, pyridoxine 5'-phosphate, pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate. 

Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. 
Pyridoxine, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA). 

Pyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.
Pyridoxine is also used in combination with for the treatment of nausea and vomiting in pregnancy.

Pyridoxine is a Vitamin B6 Analog. 
The chemical classification of Pyridoxine is Vitamin B6.


PHYSICAL PROPERTIES:

-Molecular Weight: 169.18    

-XLogP3: -0.8        

-Exact Mass: 169.07389321    

-Monoisotopic Mass: 169.07389321    

-Topological Polar Surface Area: 73.6 Ų

-Physical Description: Solid

-Melting Point: 159-162 °C

-Solubility: 220000 mg/L

-LogP: -0.77

-Collision Cross Section: 134.6 Ų

Pyridoxine plays an important role in the body. 
Pyridoxine is needed to maintain the health of nerves, skin, and red blood cells.

Pyridoxine has been used to prevent or treat a certain nerve disorder (peripheral neuropathy) caused by certain medications (such as isoniazid). 
Pyridoxine has also been used to treat certain hereditary disorders (such as xanthurenic aciduria, hyperoxaluria, homocystinuria).

Pyridoxine, vitamin B6, is required by your body for utilization of energy in the foods you eat, production of red blood cells, and proper functioning of nerves. 
Pyridoxine is used to treat and prevent vitamin B6 deficiency resulting from poor diet, certain medications, and some medical conditions.

Pyridoxine, is a form of vitamin B6 found commonly in food and used as a dietary supplement. 
As a supplement Pyridoxine is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning.

Pyridoxine is used by mouth or by injection.
Pyridoxine is usually well tolerated.

Pyridoxine is a water-soluble vitamin that your body needs for several functions.
Pyridoxine’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 3    

-Hydrogen Bond Acceptor Count: 4    

-Rotatable Bond Count: 2

-Heavy Atom Count: 12    

-Formal Charge: 0    

-Complexity: 142    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 1    

-Compound Is Canonicalized: Yes


Pyridoxine Prevents Clogged Arteries and Reduce Heart Disease Risk
Pyridoxine Helps Prevent Cancer

Pyridoxine Promotes Eye Health and Prevent Eye Diseases
Pyridoxine Treats Inflammation Associated With Rheumatoid Arthritis


SYNONYMS:

pyridoxine
vitamin B6
Pyridoxol
Gravidox
Pyridoxin
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
Hydoxin
Adermine
Pyridoxolum
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-
5-Hydroxy-6-methyl-3,4-pyridinedimethanol
Pyridoxinum
Piridossina 
3-Hydroxy-4,5-dimethylol-alpha-picoline
Pyridoxinum 
Piridossina
Pyridoxine 
Aderoxine
2-Picoline-4,5-dimethanol, 3-hydroxy-
(5-Hydroxy-6-methylpyridine-3,4-diyl)dimethanol
2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine
Hexa-Betalin
2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine
2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine
Pyridoxin hydrochloride
4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol
Pyridoxine free base
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]
4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol
2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine
Adermin hydrochloride
Pyridoxinum hydrochloricum
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin
Pyridoxine hydrogen chloride
2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine
Adermin
Bezatin
Pirivitol
Infuvite Pediatric
Pyridoxine (Vit B6)
M.V.I.-12 Lyophilized
Pridoxine
VitaminB6
Pyridoxine
Beesix 
nchembio.93-comp1
Becilan 
Benadon 
Hexobion 
Vitamin B6 
Pyridoxol, Vitamin B6
Pyridoxol; Vitamin B6
Hexabetalin 
Vitamin b6,hydrochloride
Pyridoxol, Vitamin B6, Gravidox
Pharmakon1600-01505453
3-hydroxy-2-Picoline-4,5-dimethanol
Vitamin B6 100 microg/mL in Methanol
3-Hydroxy-4,5-dimethylol-.alpha.-picoline
4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol
4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol #
2-Methyl-3-oxylato-4,5-bis(hydroxymethyl)pyridinium
2-methyl-3-hydroxy-4-hydroxymethyl-5-hydroxymethyl pyridine

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