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Red clover cellular extract is often included in anti-aging products, thought to enhance skin elasticity, reduce the appearance of wrinkles, and stimulate collagen production.
The antioxidants in red clover extract help neutralize free radicals, thereby preserving the skin’s structure and appearance over time.
Red clover cellular extract is a flowering plant native to Europe, Asia, and North America, traditionally used in folk medicine for its health benefits, particularly for skin and hair.
CAS Number: 85085-25-2
EC Number: 285-356-7
Chemical Formula: C18H18O4
Molecular Weight: 302.34 g/mol
Synonyms: Red Clover Extract, Trifolium pratense Extract, Clover Extract, Clover Flower Extract, Clover Isoflavones, Red Clover Phytoestrogens, Biochanin A Extract, Formononetin Extract, Trifolium Extract, Red Clover Tincture, Red Clover Powder, Red Clover Floral Extract, Trifolium pratense Tincture, Red Clover Concentrate, Isoflavone-Rich Clover Extract, Clover Leaf Extract, Herbal Red Clover, Red Clover Essence, Red Clover Infusion, Red Clover Oil, Red Clover Nutraceutical, Red Clover Supplement, Trifolium Infusion, Phytoestrogenic Clover, Natural Red Clover Extract, Organic Red Clover Extract, Clover Nutrient Extract, Isoflavone Extract, Clover Herbal Extract, Red Clover Botanical Extract, Clover Bloom Extract, Trifolium pratense Powder, Red Clover Concentrated Extract, Red Clover Active Extract, Red Clover Phytochemical Extract, Clover Isoflavone Supplement, Trifolium pratense Isoflavones, Herbal Clover Supplement, Red Clover Fluid Extract, Red Clover Solid Extract, Extract of Red Clover, Bioactive Red Clover, Red Clover Root Extract, Clover Bioactive Compound, Red Clover Filtrate, Red Clover Saponin Extract, Trifolium Extract for Skin, Red Clover Hormonal Support Extract, Red Clover Flower Essence, Clover Herbal Remedy
Red clover cellular extract, derived from the Trifolium pratense plant, is widely appreciated for its potential skincare and wellness benefits.
Rich in phytoestrogens like biochanin A and formononetin, Red clover cellular extract may support hormonal balance and skin health.
Often included in anti-aging products, Red clover cellular extract is thought to enhance skin elasticity, reduce the appearance of wrinkles, and stimulate collagen production.
Additionally, Red clover cellular extract's antioxidant properties help shield skin cells from oxidative damage caused by environmental stressors, such as UV exposure and pollution.
Red clover extract is used in various topical skincare formulations, including serums and creams, as well as in dietary supplements for holistic wellness benefits.
Red clover cellular extract, obtained from the Trifolium pratense plant, is highly regarded in both the skincare and wellness industries for its array of beneficial properties.
Red clover cellular extract is particularly rich in isoflavones, notably biochanin A and formononetin, which are types of phytoestrogens.
Phytoestrogens are plant-based compounds that mimic estrogen’s effects in the body, making red clover extract a popular choice for promoting hormonal balance, especially in skincare products targeting mature skin.
As skin ages, Red clover cellular extract naturally loses elasticity and firmness, leading to the formation of wrinkles and fine lines.
The phytoestrogens in red clover extract are believed to support skin vitality by stimulating collagen production and improving skin elasticity, which may help reduce the appearance of wrinkles and promote a more youthful complexion.
In addition to its potential anti-aging benefits, red clover extract is also rich in antioxidants, which play a crucial role in protecting skin cells from oxidative stress.
Environmental factors such as UV radiation, pollution, and even stress can lead to the formation of free radicals, which damage skin cells and accelerate aging.
The antioxidants in red clover extract help neutralize these free radicals, thereby preserving the skin’s structure and appearance over time.
This protective effect makes red clover an appealing ingredient in products designed to repair and rejuvenate the skin, especially for those exposed to urban or high-pollution environments.
Beyond its topical applications, red clover extract is also available in supplement form and is used holistically for its wellness benefits.
By helping to regulate hormonal balance, red clover may alleviate some of the symptoms associated with hormonal changes, such as those experienced during menopause.
In skincare, Red clover cellular extract is often incorporated into creams, serums, and anti-aging formulations, providing a natural way to nurture and restore the skin.
Whether applied topically or taken as a supplement, Red clover cellular extract represents a botanical approach to supporting skin health, cellular rejuvenation, and overall wellness, making it a versatile addition to both skincare and wellness routines.
Red clover cellular extract delivers the natural molecules this botanical species can offer in a water-soluble format, including ryptophan, adenosine, quercetin, kaempferol, coumestrol, isoflavones, amino acids, and a range of phenolics, to power your products naturally.
Red clover cellular extract's unique synergy between its compounds delivers a powerhouse of natural ingredients to consider for skincare, hydration, haircare, premature aging and more along with beautiful new imagery to create unique content for your brand.
Red clover is a wild edible plant that has a long and colourful history.
Traditional Chinese medicine believed that Red clover cellular extract was a good tonic for colds.
Today, Red Clovers phyto-compounds are translated through cosmetics, body products, haircare, and bath products.
Delivering True to Nature hydrophilic plant profiles, Cellular Extraction harnesses a species' water-soluble blueprint of phyto-compounds and their derivatives (which we call the entourage) suspended in a liquid medium.
Extracted rapidly under high pressure, we capture the natural molecules.
Committed to conscious manufacturing, Cellular Extracts are created using purified, deionised rain-harvested water, and less plant material to produce a True to Nature extract.
With attention to eco-responsible practices, traceable to source and transparent in composition - Cellular Extracts deliver the brilliance of nature.
Red clover cellular extract is a traditional Chinese medicine and use as herbal medicine which has the effects of regulating menopausal symptoms, heart problem, inflammatory disease, psoriasis and cognitive deficits.
In previous reported, the studies of red clover were mainly focused on clinical practice.
The pharmacological functions of red clover not fully elucidated.
Red clover cellular extract is a flowering plant that grows 15-40 cm high.
Red clover cellular extracts eaten as a legume and used in supplements marketed for female health.
Red clover cellular extract contains chemicals called phytoestrogens that are similar to the hormone estrogen.
Red clover cellular extract grows in many areas, including Europe, central Asia, and northern Africa.
People commonly use red clover for symptoms of menopause, weak and brittle bones, breast pain, male-pattern baldness, and many other conditions, but there is no good scientific evidence to support any of these uses.
Red clover cellular extract is a flowering plant native to Europe, Asia, and North America.
Traditionally used in folk medicine, Red clover cellular extract has been valued for its health benefits for centuries, particularly for skin and hair health.
Extracted from the blossoms, red clover is rich in bioactive compounds that contribute to its beneficial effects.
Red clover cellular extract is a plant in the Fabaceae (legume) family that is a source of isoflavones with estrogen-like effects, similar to soy.
Red clover cellular extract has primarily been researched as a supplement in menopause and might reduce the frequency of hot flashes, but other menopause-related outcomes have been largely inconclusive.
Red clover cellular extract is a perennial plant in the legume family (Fabaceae).
Red clover cellular extract grows in many regions of the world, including North America, Europe, Asia, and Africa.
The aerial (above-ground) parts of the red clover plant have been used as a traditional herbal medicine for a variety of ailments, but the research on red clover has generally centered around menopause.
Red clover cellular extract contains bioactive plant compounds called isoflavones which possess phytoestrogenic properties.
While 16 different isoflavones have been identified in red clover, biochanin A and formononetin are thought to be the most abundant.
Interestingly, upon consumption, biochanin A and formononetin are metabolized into genistein and daidzein (the same isoflavones found in soy), respectively, which are the dominant isoflavones found in the blood during red clover supplementation.
Red clover cellular extract, meadow or even honey lotus, this plant comes from the butterfly plant family and is used in medicine because it contains plant hormones for the treatment of menopausal symptoms.
In skin care, Red clover cellular extract is particularly useful as a remedy for eczema and psoriasis.
Due to the high content of isoflavones, Red clover cellular extractcontains powerful antioxidants, is skin regenerating and stimulates the cellular metabolism of the skin, which also makes it especially suitable for the care of dry and mature skin.
Uses of Red Clover Cellular Extract:
Red clover cellular extract is a versatile ingredient widely used in skincare and wellness products due to its rich content of phytoestrogens and antioxidants.
In anti-aging skincare, Red clover cellular extract supports collagen production and improves skin elasticity, helping to reduce fine lines and wrinkles.
Red clover cellular extract's hormonal balancing properties, thanks to natural isoflavones, make it beneficial for women experiencing menopausal symptoms, as it may help ease discomfort and support skin health during hormonal changes.
Additionally, Red clover cellular extract's antioxidants provide strong protection against free radicals, shielding the skin from damage caused by environmental stressors like UV rays and pollution, which can lead to premature aging.
Red clover is also valued for its moisturizing and soothing effects, making it a common ingredient in products for sensitive or inflamed skin.
Beyond topical applications, it’s available in supplement form to support overall wellness, including cardiovascular health and cellular function.
This range of benefits makes red clover extract a popular choice for those seeking natural, holistic approaches to skin and health care.
Red clover cellular extract offers a range of uses, particularly in skincare and wellness due to its beneficial compounds:
Anti-Aging Skincare:
Red clover extract is rich in phytoestrogens, which help boost collagen production and skin elasticity.
This makes Red clover cellular extract a popular ingredient in anti-aging creams and serums to reduce the appearance of fine lines and wrinkles.
Hormonal Support:
As a natural source of isoflavones, red clover extract may help balance hormones, especially in women.
This can be beneficial during menopause, potentially easing symptoms like hot flashes and supporting skin health.
Antioxidant Protection:
Red clover cellular extract’s high antioxidant content aids in protecting the skin from oxidative damage caused by free radicals, which can be triggered by UV exposure, pollution, and stress.
This protection can help slow signs of premature aging.
Skin Conditioning:
Red clover is used in various moisturizers and conditioning agents to hydrate the skin, leaving it soft, smooth, and more resilient.
Soothing and Calming Effects:
Known for its soothing properties, red clover extract can be used in skincare formulations to reduce redness and irritation, making it suitable for sensitive or inflamed skin.
Nutritional Supplement:
Often taken as a supplement, red clover extract may promote overall wellness, supporting cardiovascular health and providing beneficial nutrients for cellular function and health maintenance.
Benefits of Red Clover Cellular Extract:
Red clover cellular extract may be a beneficial supplement in menopause when used to reduce hot flashes.
A 2021 meta-analysis of randomized controlled trials found that Red clover cellular extract supplementation taken for 3 months resulted in an average of 1.7 fewer hot flashes daily compared to placebo, particularly in postmenopausal women experiencing at least 5 hot flashes daily.
However, these effects were not sustained in trials performing a 12-month follow-up, and over half of the trials were at least partially funded by the red clover manufacturer, which could bias these results.
Red clover cellular extract might slightly reduce total cholesterol and raise high-density lipoprotein (HDL) in postmenopausal women with no other health conditions, but the effects are so small they likely would not influence overall cardiovascular health.
Research looking at other menopause-related outcomes like vaginal health, sleep behavior, mood, and bone health have had mixed results and are currently inconclusive.
Preclinical research suggests that Red clover cellular extract may possess antioxidant, antimicrobial, and hypoglycemic (blood-sugar-reducing) properties, but establishing the clinical relevance of these effects will require further research.
Red clover cellular extract offers multiple benefits, particularly in skincare and wellness:
Anti-Aging Effects:
Red clover is rich in phytoestrogens, which stimulate collagen production, improve skin elasticity, and reduce the appearance of wrinkles, promoting a youthful complexion.
Hormonal Balance:
The isoflavones in red clover mimic estrogen’s effects, helping balance hormones.
This can be especially beneficial for women experiencing menopausal symptoms, potentially reducing hot flashes and skin dryness.
Antioxidant Protection:
With a high antioxidant content, red clover extract defends the skin against free radicals caused by UV exposure, pollution, and stress, which can accelerate skin aging.
Moisturizing and Conditioning:
Red clover helps hydrate and soften the skin, making it a valuable ingredient in moisturizers and conditioners, leaving skin smoother and more resilient.
Calming and Soothing:
Known for its soothing properties, red clover can help reduce redness and irritation, making it ideal for sensitive or reactive skin types.
Nutritional Wellness:
As a supplement, red clover may support cardiovascular health and cellular function, contributing to overall wellness and vitality.
Science of Red Clover Cellular Extract:
Red clover cellular extract is renowned for its high content of isoflavones, especially biochanin A and formononetin.
These phytoestrogens help balance scalp health and are known for their antioxidant properties, which protect hair and scalp from environmental damage.
The isoflavones in red clover extract also inhibit the enzyme 5-α-reductase, which is linked to the production of DHT, a hormone associated with hair thinning.
Properties of Red Clover Cellular Extract:
Red clover cellular extract is a powerful ingredient with a variety of beneficial properties that make it popular in skincare and wellness products.
Rich in phytoestrogens, especially isoflavones like biochanin A and formononetin, Red clover cellular extract helps balance hormones, which is particularly helpful for skin health and women’s wellness during hormonal shifts.
Red clover cellular extract's strong antioxidant properties protect skin cells from free radicals caused by environmental stressors, helping to prevent premature aging.
Red clover is also known for its anti-inflammatory qualities, making it effective at calming irritated or sensitive skin and reducing redness.
Additionally, Red clover cellular extract supports collagen production, enhancing skin elasticity and firmness, which can reduce wrinkles and fine lines.
With natural moisturizing and nutrient-rich properties, Red clover cellular extract hydrates and nourishes the skin, boosting its resilience and promoting cellular health.
These combined qualities make Red clover cellular extract a versatile and effective choice for supporting skin vitality and overall wellness.
Productions of Red Clover Cellular Extract:
The production of Red clover cellular extract involves several stages to ensure the extract retains its beneficial properties for skincare and wellness applications:
Harvesting:
Red clover plants (Trifolium pratense) are carefully harvested, typically when they reach peak bloom to maximize the concentration of bioactive compounds, such as isoflavones and antioxidants.
Drying and Processing:
The harvested plants are dried and processed to prevent degradation of active compounds.
This step ensures that Red clover cellular extract remains potent and effective.
Extraction:
Using methods like cold-pressing, solvent extraction, or supercritical CO₂ extraction, the dried plant material is processed to isolate essential bioactives.
Each method is chosen based on the desired purity and concentration of isoflavones, antioxidants, and other beneficial compounds.
Purification:
The raw extract undergoes purification to remove unwanted components and concentrate key ingredients.
This process enhances the efficacy of the final product while ensuring Red clover cellular extract meets quality and safety standards.
Formulation:
The purified extract is often standardized to ensure consistent levels of bioactive compounds.
Red clover cellular extract is then incorporated into various products, including creams, serums, supplements, and wellness formulations.
Quality Control and Testing:
Rigorous quality checks, such as testing for potency, purity, and safety, are conducted to ensure that Red clover cellular extract meets industry standards.
These tests confirm that Red clover cellular extract maintains its intended benefits for skincare and health.
The final Red clover cellular extract is then packaged and prepared for distribution, ready to be used as a potent, natural ingredient in products focused on anti-aging, hydration, and hormonal support.
Synthesis of Red Clover Cellular Extract:
The synthesis of Red clover cellular extract, while typically derived naturally from the Trifolium pratense plant, can also involve biochemical techniques to isolate or even synthetically reproduce its active compounds, especially when purity and consistency are desired for large-scale production.
Here is an overview of the synthesis process:
Isolation of Key Compounds:
In natural synthesis, bioactive compounds like isoflavones (biochanin A, formononetin) are extracted from red clover plants.
Advanced extraction techniques, such as solvent extraction or supercritical CO₂ extraction, help to isolate these compounds with minimal degradation.
Synthetic Reproduction of Isoflavones:
In cases where a high concentration or specific purity is required, the key isoflavones can be synthesized in a lab.
Starting from simpler precursor molecules, biochanin A and formononetin can be produced through chemical synthesis involving steps like hydroxylation, methylation, and glycosylation to mirror their natural structure.
Combination and Blending:
The natural and/or synthetic isoflavones are then blended to match the composition found in the red clover plant.
This standardized blend ensures consistency in bioactive content across batches, enhancing the efficacy and stability of the final extract.
Encapsulation for Stability:
To improve stability and bioavailability, especially for use in skincare products, the synthesized or extracted compounds may be encapsulated in lipid carriers or emulsions.
Encapsulation protects the active ingredients from oxidation and allows for controlled release when applied to the skin.
Formulation and Testing:
The synthesized extract undergoes formulation into skincare and wellness products, with rigorous testing to confirm the stability, potency, and safety of the synthesized compounds.
This ensures that they deliver the intended benefits of natural red clover.
This synthesis approach allows manufacturers to produce consistent, potent red clover extracts with enhanced stability, meeting the demands for anti-aging, hydrating, and hormonal support products while preserving the essential properties of the plant.
Handling and Storage of Red Clover Cellular Extract:
Handling:
Handle with care to avoid contamination.
Use appropriate protective equipment (gloves, safety glasses, etc.) when handling concentrated extracts.
Ensure the work area is well-ventilated.
Avoid direct inhalation or ingestion.
Storage:
Store in a cool, dry place, away from direct sunlight and heat.
Store in tightly sealed containers to avoid contamination or degradation.
Keep away from strong acids, bases, and oxidizing agents.
Ideal storage temperature: 15-25°C (59-77°F).
Avoid freezing, which may damage the extract.
Stability and Reactivity of Red Clover Cellular Extract:
Stability:
Red Clover Cellular Extract is stable under recommended storage conditions (cool, dry, and away from light).
If exposed to excessive heat or moisture, the extract may degrade, losing potency or becoming less effective.
Reactivity:
Reacts with strong acids and bases, which may cause breakdown or neutralization of active compounds.
May react with oxidizing agents, leading to decomposition.
Avoid contact with open flames or high temperatures as this may cause decomposition.
First Aid Measures of Red Clover Cellular Extract:
Inhalation:
If inhaled in excess, move to fresh air immediately.
Seek medical attention if symptoms persist.
Skin Contact:
Wash the affected area with plenty of water.
Remove contaminated clothing.
Seek medical advice if irritation occurs.
Eye Contact:
Rinse eyes with water for at least 15 minutes, lifting the eyelids occasionally.
Seek medical attention if irritation persists.
Ingestion:
Rinse the mouth with water.
Do not induce vomiting unless instructed by a healthcare professional.
Seek medical attention if necessary.
Firefighting Measures of Red Clover Cellular Extract:
Suitable Extinguishing Media:
Use dry chemical, foam, or CO₂ fire extinguishers.
Fire Fighting Instructions:
Use water spray to cool down fire-exposed containers.
Wear self-contained breathing apparatus (SCBA) and protective clothing to prevent exposure to fumes.
In case of a fire, evacuate the area and prevent inhalation of smoke and fumes.
Accidental Release Measures of Red Clover Cellular Extract:
Personal Precautions:
Wear appropriate protective equipment (gloves, safety goggles, etc.).
Avoid inhaling dust or vapor released from the extract.
Environmental Precautions:
Prevent the extract from entering waterways or drains.
Contain the spill to avoid contamination of the surrounding area.
Cleanup Methods:
For spills, absorb the material with inert material (e.g., sand, vermiculite).
Sweep up and place in an appropriate disposal container.
Dispose of according to local regulations.
Exposure Controls/Personal Protective Measures of Red Clover Cellular Extract:
Occupational Exposure Limits:
No specific occupational exposure limits established for Red Clover Cellular Extract, but standard safety precautions should be followed.
Engineering Controls:
Ensure good ventilation in the working area.
Use local exhaust ventilation if necessary to minimize exposure.
Personal Protective Equipment (PPE):
Eyes:
Safety goggles or face shield to protect against splashes.
Skin:
Wear gloves and protective clothing to avoid skin contact.
Respiratory:
Wear a suitable NIOSH-approved mask or respirator if there is a risk of inhaling dust or vapors.
Identifiers of Red Clover Cellular Extract:
CAS: 85085-25-2
EC: 285-356-7
INCI: Trifolium pratense Extract; Trifolium pratense (Clover) Flower Extract
Common Name: Red Clover
Scientific Name: Trifolium pratense
Chemical Formula: C₁₈H₁₈O₄
Molecular Weight: 302.34 g/mol
Active Ingredients: Isoflavones (biochanin A, formononetin)
Extraction Method: Cold-pressed, ethanol, supercritical CO₂
Plant Part Used: Flowers, leaves
Therapeutic Properties: Estrogenic, antioxidant, anti-inflammatory
Usage Forms: Liquid extract, powder, capsules
Shelf Life: 1 to 3 years
Storage Conditions: Cool, dry place, away from sunlight
Specifications of Red Clover Cellular Extract:
Microbial Limits:
Total plate count: < 1000 CFU/g
Yeast and mold: < 100 CFU/g
Pathogens: Absent (E. coli, Salmonella)
Heavy Metals:
Lead: < 10 ppm
Arsenic: < 2 ppm
Cadmium: < 1 ppm
Mercury: < 0.5 ppm
Other Extract Options:
Dilution 1:10
Ethanolic
Organic
