Salicylic Acid Cosmetic Grade can be used as an antiseptic, to treat acne and warts.
Salicylic Acid Cosmetic Grade can be used in pharmaceuticals, and as a powder in cosmetics.
Salicylic Acid Cosmetic Grade also can serve as an anti-dandruff agent, denaturant, exfoliant, hair conditioning agent, preservative, and skin conditioning agent with keratolytic properties.
CAS-Number: 69-72-7
EC Number: 200-712-3
MDL number: MFCD00002439
Chemical Name: 2 – Hydroxybenzoic Acid
Linear Formula: 2-(HO)C6H4CO2H
Molecular Formula: C7H6O3
SYNONYMS:
salicylic acid, 2-Hydroxybenzoic acid, 69-72-7, o-hydroxybenzoic acid, 2-Carboxyphenol, o-Carboxyphenol, Rutranex, Salonil, Retarder W, Duoplant, Keralyt, Psoriacid-S-stift, Freezone, Saligel, Ionil, Benzoic acid, 2-hydroxy-, Salicylic acid soap, Stri-Dex, Verrugon, Salicylic acid collodion, Acidum salicylicum, Trans-Ver-Sal, 2-Hydroxybenzenecarboxylic acid, Phenol-2-carboxylic acid, Orthohydroxybenzoic acid, Salicyclic acid, Acido salicilico, Kyselina salicylova, Salicylic acid, tech., Duofilm, Ionil-Plus, Dr. Scholl's callus removers, Clear away wart remover, Duofil wart remover, Domerine, Occlusal, Sebucare, Sebulex, Mediplast pads, Akurza Lotion, Hydrisalic Gel, Kyselina 2-hydroxybenzoova, Akurza Cream, Ionil plus, Salex Lotion, Salex Cream, DuoPlant Gel, Caswell No. 731, salicylicum acidum, DHS Sal Shampoo, P&S Shampoo, NSC 180, Advanced pain relief corn removers, Acido o-idrossibenzoico, Benzoic acid, hydroxy-, Advanced pain relief callus removers, CCRIS 6714, AI3-02407, Propa pH Peel-Off Acne Mask, Salicylic acid & Sulfur Soap, MFCD00002439, 2-hydroxy-benzoic acid, EPA Pesticide Chemical Code 076602, Anti-blemish, CHEBI:16914, BRN 0774890, NSC-180, UNII-O414PZ4LPZ, EINECS 200-712-3, O414PZ4LPZ, DTXSID7026368, FEMA NO. 3985, Bazuka Extra Strength Gel, CHEMBL424, Salicylic acid [USP:JAN], MLS000069653, DTXCID206368, NSC180, 29656-58-4, K 537, EC 200-712-3, ATA fraction 10, ammonium salt, NCGC00159447-05, SMR000059163, Acid, Salicylic, ortho-Hydroxybenzoic Acid, Salicylic acid (USP:JAN), SALICYLIC ACID (USP), SALICYLIC ACID [USP], o Hydroxybenzoic Acid, SALICYLIC ACID (MART.), SALICYLIC ACID [MART.], SALICYLIC ACID (USP-RS), Salicylic acid [USAN:JAN], SALICYLIC ACID [USP-RS], 2 Hydroxybenzoic Acid, Acid, o-Hydroxybenzoic, Acid, 2-Hydroxybenzoic, ortho Hydroxybenzoic Acid, SALICYLIC ACID (EP IMPURITY), SALICYLIC ACID [EP IMPURITY], SALICYLIC ACID (EP MONOGRAPH), SALICYLIC ACID (USP MONOGRAPH), CAS-69-72-7, LAMIVUDINE IMPURITY C (EP IMPURITY), NSC629474, phenol derivative, 7, Salicylic acid (TN), 2-Hydroxybenzoic acid, 2-HYDROXYBENZOIC ACID, ACIDUM SALICYLICUM, ACETYLSALISYLIC ACID IMP C, ACETYLSALICYLIC ACID IMPURITY C, FEMA 3985, SALICYCLIC ACID, SALICYLIC ACID, RETARDER TSA, salicylic acid, 2-Hydroxybenzoic acid, 69-72-7, o-hydroxybenzoic acid, 2-Carboxyphenol, o-Carboxyphenol, Rutranex, Salonil, Retarder W, Duoplant, Keralyt, Psoriacid-S-stift, Freezone, Saligel, Ionil, Salicylic acid soap, Stri-Dex, Verrugon, Salicylic acid collodion, Benzoic acid, 2-hydroxy-, 2-Hydroxybenzenecarboxylic acid, Phenol-2-carboxylic acid, Orthohydroxybenzoic acid, Acido salicilico, Kyselina salicylova, 2-hydroxy-benzoic acid, CCRIS 6714, HSDB 672, AI3-02407, CHEBI:16914, BRN 0774890, NSC-180, UNII-O414PZ4LPZ, EINECS 200-712-3, O414PZ4LPZ, MFCD00002439, DTXSID7026368, FEMA NO. 3985, CHEMBL424, MLS000069653, DTXCID206368, NSC180, K 537, EC 200-712-3, 29656-58-4, SMR000059163, Acid, Salicylic, ortho-Hydroxybenzoic Acid, o Hydroxybenzoic Acid, 2 Hydroxybenzoic Acid, Acid, o-Hydroxybenzoic, Acid, 2-Hydroxybenzoic, ortho Hydroxybenzoic Acid, Acid, ortho-Hydroxybenzoic, NSC629474, phenol derivative, 7, Salicylic acid (TN), SCHEMBL1967, SALICYLIC ACID [MI], Oprea1_040343, KBioSS_001428, BIDD:ER0602, NCGC00159447-01, NCGC00159447-02, NCGC00159447-04, NCGC00159447-06, NCGC00257065-01, NCGC00259022-01, FT-0645123, FT-0674502, FT-0674503, H0206, H1342, Salicylic Acid Technical Grade, Unichem Salac, 2-Hydroxybenzoic acid, 2-Carboxyphenol, Salicylic acid, 2-HYDROXYBENZOIC ACID,ACIDUM SALICYLICUM, ACETYLSALISYLIC ACID IMP C,ACETYLSALICYLIC ACID IMPURITY C,FEMA 3985,SALICYCLIC ACID,SALICYLIC ACID,RETARDER TSA, Salicylic, Acid,Salicylic, 2 Hydroxybenzoic Acid, Acido Salicilico, Sa - Salicylic Acid, O-Hydroxybenzoic Acid, O Hydroxybenzoic Acid, Salicylic Aci, Acid,2-Hydroxybenzoic, Acidum Salicylicum, O-Carboxyphenol, Salicylic Acid Preparation, Acid,O-Hydroxybenzoic, Kyselina Salicylova, Salicylic Preparation, Acid,Ortho-Hydroxybenzoic, Acido O-Idrossibenzoico, Kyselina 2-Hydroxybenzoova, Caswell No. 731, Benzoic Acid,2-Hydroxy- (10), 2-Carboxyphenol,2-Hydroxybenzenecarboxylate, 2-Hydroxybenzenecarboxylic acid, 2-Hydroxybenzoate, 2-Hydroxybenzoic acid, Benzoic acid, 2-hydroxy-, Benzoic acid, o-hydroxy-, o-Carboxyphenol, o-Hydroxybenzoate, o-Hydroxybenzoic acid, Orthohydroxybenzoic acid, Phenol-2-carboxylate, Phenol-2-carboxylic acid, Psoriacid-S-Stift, Salicyclic acid, Salicylate, Salicylic acid, Saligel, Salonil, Trans-Ver-Sal, 2 Hydroxybenzoic acid Acid, 2-hydroxybenzoic, Acid, salicylic, Acid, O-hydroxybenzoic, Acid, ortho-hydroxybenzoic, O Hydroxybenzoic acid, Ortho hydroxybenzoic acid, Ortho-hydroxybenzoic acid, Advanced pain relief callus removers, Advanced pain relief corn removers, Clear away wart remover, Compound W, Duofil wart remover, Duoplant, Freezone, Ionil, Ionil plus, K 537, K 557, Retarder W, Rutranex, Salicylic acid collodion, Salicylic acid soap, Stri-dex, SA, Benzoic acid, 2-hydroxy-, o-Hydroxybenzoic acid, Phenol-2-carboxylic acid, Psoriacid-S-Stift, Retarder W, Rutranex, Salicylic acid collodion, Salonil, 2-Hydroxybenzoic acid, Acido salicilico, Keralyt, Kyselina 2-hydroxybenzoova, Kyselina salicylova, Orthohydroxybenzoic acid, Duoplant, Freezone, Ionil, Saligel, Compound W, 2-Hydroxybenzenecarboxylic acid, 2-Carboxyphenol, o-Carboxyphenol, Advanced pain relief callus removers, Advanced pain relief corn removers, Clear away wart remover, Dr. Scholl's Callus Removers, Duofil Wart Remover, Ionil plus, Salicylic acid soap, Stri-Dex, Benzoic acid, o-hydroxy-, NSC 180, Trans-Ver-Sal, Domerine, Duofilm, Fostex, Pernox, Salicylic acid & Sulfur Soap, Sebucare, Sebulex, component of Fostex medicated bar and cream, component of Keralyt, Retarder SAX, component of Solarcaine first aid spray, component of Tinver, 7681-06-3, 8052-31-1, Salicyclic acid, Domerine (Salt/Mix), Duofilm (Salt/Mix), Fostex (Salt/Mix), Pernox (Salt/Mix), Salicylic acid & Sulfur Soap (Salt/Mix), Sebucare (Salt/Mix), Sebulex (Salt/Mix), component of Fostex medicated bar and cream (Salt/Mix), component of Keralyt (Salt/Mix), Retarder SAX (Salt/Mix), component of Solarcaine first aid spray (Salt/Mix), component of Tinver (Salt/Mix)
Salicylic Acid Cosmetic Grade is also called acidum salicylicum or o-hydroxybenzoic acid.
Its name comes from the Latin word salix, meaning willow tree, from whose bark Salicylic Acid Cosmetic Grade was first extracted.
This organic compound is classified as aromatic hydroxy acid, and accordingly Salicylic Acid Cosmetic Grade has a carboxyl group (COOH) and a hydroxyl group (OH).
The chemical formula of Salicylic Acid Cosmetic Grade is as follows: C7H6O3.
The discovery of Salicylic Acid Cosmetic Grade is attributed to an Italian chemist, Raffaele Piria, who lived from 1814 to 1865.
He was the first person to research the properties of salicin.
In the 1850s, acidum salicylicum was isolated by a German chemist, Hermann Kolbe.
Salicylic Acid Cosmetic Grade is an organic compound that appears as a colorless solid.
Salicylic Acid Cosmetic Grade is a beta-hydroxy acid that is naturally present in the bark of the White Willow tree.
Salicylic Acid Cosmetic Grade's one of the gold standard ingredients for treating skin problems and is present in many anti-acne products.
Salicylic Acid Cosmetic Grade is a pale pink to off-white powder that is mainly used for anti-acne products.
Salicylic Acid Cosmetic Grade is among the most important medicinal compounds ever discovered.
Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to Salicylic Acid Cosmetic Grade and provide analgesic, anti-inflammatory and antipyretic benefits.
Today, synthetic Salicylic Acid Cosmetic Grade continues to play an important role as an active ingredient in over-the-counter (OTC) topical drug products and as a precursor to other drug compounds such as aspirin (acetylsalicylic acid), methyl salicylate and the sunscreen actives homosalate and octisalate.
Salicylic Acid Cosmetic Grade is also a critical starting material for the synthesis of certain fragrance ingredients, including benzyl salicylate and isoamyl salicylate.
Salicylic Acid Cosmetic Grade is notorious for its dissolving and pH issues in formulations.
This water-soluble Salicylic Acid Cosmetic Grade solves those problems for formulators and DIYers.
Salicylic Acid Cosmetic Grade is a high-quality cosmetic-grade ingredient that ensures the quality of our final products.
Salicylic Acid Cosmetic Grade is like any other water-soluble ingredient for toner, serum, or emulsions.
Salicylic Acid Cosmetic Grade is a plant willow bark extract, and also a natural anti-inflammatory drugs.
Commonly used aspartic acid aspirin is the Salicylic Acid Cosmetic Grade derivatives of acetyl salicylate, and sodium aminosalicylate (PAS) is a commonly used anti-TB drugs.
Salicylic Acid Cosmetic Grade in dermatology commonly used in the treatment of various chronic skin diseases such as acne (acne), ringworm and so on.
Salicylic Acid Cosmetic Grade can remove the horny, sterilization, anti-inflammatory, which is very suitable for the treatment of acne caused by clogs, the international mainstream acne products are salicylic acid, the concentration is usually 0.5 to 2%.
Salicylic Acid Cosmetic Grade is an active skin care exfoliant and the family of Beta Hydroxy Acids.
Salicylic Acid Cosmetic Grade is very useful for treating acne and for making cosmetic products for sensitive acne prone skin.
Salicylic Acid Cosmetic Grade is a natural anti-inflammatory drugs.
Salicylic Acid Cosmetic Grade can help curing chronic skin diseases such as acne and hemorrhoids.
Salicylic Acid Cosmetic Grade is a high-purity, pharmaceutical-grade ingredient widely used in skincare formulations.
Known for its ability to exfoliate and unclog pores, this white crystalline powder, Salicylic Acid Cosmetic Grade is a staple in acne treatments, peels, and anti-aging products.
Salicylic Acid Cosmetic Grade offers excellent solubility in alcohol and partially in water, making it versatile for various cosmetic applications.
Salicylic Acid Cosmetic Grade is an odourless slightly off-white crystaline powder.
Salicylic Acid Cosmetic Grade has germicidal properties. (antiseptic), exfoliates skin cells (keratolytic), anti-dandruff (anti-dandruff) has the effect of dissolving clogged pores. Salicylic Acid Cosmetic Grade dissolves dirt stuck in the pores.
Salicylic Acid Cosmetic Grade cannot dissolve in water.
Salicylic Acid Cosmetic Grade is a naturally occuring and synthetically produced beta hydroxy acid used in skin treatment products.
Salicylic Acid Cosmetic Grade is an odorless white to light tan solid.
Salicylic Acid Cosmetic Grade sinks and mixes slowly with water.
Salicylic Acid Cosmetic Grade is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position.
Salicylic Acid Cosmetic Grade is obtained from the bark of the white willow and wintergreen leaves.
Salicylic Acid Cosmetic Grade has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite, an algal metabolite and a plant hormone.
Salicylic Acid Cosmetic Grade is a conjugate acid of a salicylate.
Salicylic Acid Cosmetic Grade is a compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically.
Salicylic Acid Cosmetic Grade has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic Acid Cosmetic Grade has been reported in Camellia sinensis, Dischidia formosana, and other organisms with data available.
Salicylic Acid Cosmetic Grade is a beta hydroxy acid that occurs as a natural compound in plants.
Salicylic Acid Cosmetic Grade has direct activity as an anti-inflammatory agent and acts as a topical antibacterial agent due to its ability to promote exfoliation.
Salicylic Acid Cosmetic Grade is a small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 12 approved and 15 investigational indications.
Salicylic Acid Cosmetic Grade is a compound obtained from the bark of the white willow and wintergreen leaves.
Salicylic Acid Cosmetic Grade has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic Acid Cosmetic Gradeis a desmolytic ingredient, which means it is able to exfoliate by dissolving the bonds that hold the dead cells to skin’s surface.
Because Salicylic Acid Cosmetic Grade is oil soluble, it also has the ability to penetrate into the pore lining and exfoliate inside the pore.
This makes Salicylic Acid Cosmetic Grade especially effective for reducing breakouts, including blackheads and whiteheads.
Salicylic Acid Cosmetic Grade is recognized as an over-the-counter topical acne product by the U.S. FDA, when used in concentrations of 0.5-2%.
Even though Salicylic Acid Cosmetic Grade is best known for its ability to address acne-prone skin concerns, it offers many additional properties that any skin type can benefit from.
Case in point, by exfoliating the buildup of dead skin on the surface, Salicylic Acid Cosmetic Grade also helps reverse the appearance of dull, uneven skin tone, as well as other visible signs of aging skin.
Unlike physical exfoliants (such as a rough facial scrub), Salicylic Acid Cosmetic Grade offers hydrating properties that enhance the result of smooth, soft skin.
Another unique advantage is Salicylic Acid Cosmetic Grade’s ability to gently soothe aggravated skin thanks to its inherent calming properties.
Salicylic Acid Cosmetic Grade works most effectively as a leave-on treatment, ideally within a pH range between 3 and 4.
Rinse-off Salicylic Acid Cosmetic Grade cleansers typically have a higher pH, which likely won’t offer much of an exfoliation benefit, not to mention the contact time with skin is very brief - but the salicylic acid may at least offer skin-calming benefits in this form and can be included in amounts as low as 0.5% to achieve this benefit.
Research shows using Salicylic Acid Cosmetic Grade starting at a 1-2% concentration is recommended for regular exfoliation within a skin care routine.
For more stubborn concerns, higher concentrations can make a dramatic difference.
In dermatologic practices,Salicylic Acid Cosmetic Grade has been safely used in as high as 50% concentrations for removal of warts, corns, pigmented lesions, and other advanced concerns.
USES and APPLICATIONS of SALICYLIC ACID COSMETIC GRADE:
Salicylic Acid Cosmetic Gradeis difficult to dissolve in water easily soluble in ethanol, ether, acetone and other solvents, but adding solubilizer can help it to dissolve in water system.
Salicylic Acid Cosmetic Grade is a small molecule acid with strong permeability.
Salicylic Acid Cosmetic Grade has lipophilic and exfoliating effects, and has a good therapeutic effect on melasma, post-inflammatory pigmentation, rough skin and photoaging symptoms.
Salicylic Acid Cosmetic Grade also can remove dead cells, balance excessive keratinization, and make the face smooth and elastic.
Thus Salicylic Acid Cosmetic Grade can be recommended for keratinization abnormalities, whitening, anti-acne, anti-aging/photoaging and other products.
Besides being an exfoliant, Salicylic Acid Cosmetic Grade has many other uses.
Salicylic Acid Cosmetic Grade is a chemical compound that has many different uses.
Salicylic Acid Cosmetic Grade can be used as an antiseptic, to treat acne and warts.
Salicylic Acid Cosmetic Grade can be used in pharmaceuticals, and as a powder in cosmetics.
Salicylic Acid Cosmetic Grade also can serve as an anti-dandruff agent, denaturant, exfoliant, hair conditioning agent, preservative, and skin conditioning agent with keratolytic properties.
Salicylic Acid Cosmetic Grade can be used in a wide range of personal care and cosmetic products in the formulation of moisturizers, skin cleansing products, shampoos, as well as skin care, hair care, products designed to remove corns, calluses and warts, suntan and sunscreen products.
In the cosmetics and personal care industry, Salicylic Acid Cosmetic Grade may be employed as an active ingredient with a claimed therapeutic function or as an excipient; i.e., an inactive or cosmetic ingredient.
Due to its keratolytic activity, Salicylic Acid Cosmetic Grade is an effective therapeutic1, 3, 7-8 for treating hyperkeratotic and scaling conditions, e.g., psoriasis and seborrheic dermatitis, as it promotes the safe removal of excess dead cells from the surface of healthy skin.
Through the same action, in topical acne treatments, Salicylic Acid Cosmetic Grade helps to clear the pores of comedones and prevent the formation of new ones.
It has also been postulated that the antimicrobial and anti-inflammatory properties of Salicylic Acid Cosmetic Grade may play a role in its efficacy against acne, though this theory remains subject to debate.
When Salicylic Acid Cosmetic Grade is not claimed as an OTC active ingredient, it may be added to formulations as a cosmetic ingredient where it can function as a preservative, pH adjuster, denaturant, and skin- and hair-conditioning agent.
Salicylic Acid Cosmetic Grade concentrations in cosmetic formulations are reported to range from 0.0008%–3%.
Finally, a variety of technologies have been developed to achieve the targeted, sustained delivery of Salicylic Acid Cosmetic Grade for maximum efficacy with reduced irritation.
Most of these technologies function using polymeric materials to encapsulate the Salicylic Acid Cosmetic Grade in particulates or to entrain it in films.
When applied to the skin, Salicylic Acid Cosmetic Grade is then gradually released from these matrices.
Cationic encapsulates of Salicylic Acid Cosmetic Grade have also been developed to enhance its delivery from rinse-off systems.
Acne Treatments uses of Salicylic Acid Cosmetic Grade: Effectively treats acne by exfoliating dead skin cells and reducing inflammation.
Exfoliating Products: Salicylic Acid Cosmetic Grade helps in shedding dead skin cells, leaving the skin smoother and brighter.
Anti-Aging Creams: Salicylic Acid Cosmetic Grade reduces fine lines and wrinkles by promoting cell turnover.
Peels and Masks: Salicylic Acid Cosmetic Grade is used in chemical peels for deep exfoliation.
Dandruff Treatments: Salicylic Acid Cosmetic Grade is included in shampoos to reduce dandruff and scalp irritation.
Salicylic Acid Cosmetic Grade is in compliance with the United States Pharmacopeia (USP) making it suitable for skincare products, drugs, and similar applications such as the manufacture of soap, shampoo, and cosmetics.
The sodium salt of Salicylic Acid Cosmetic Grade is added to mouthwashes and toothpastes to fight bacteria build up.
Common Uses and Applications of Salicylic Acid Cosmetic Grade:
Treatment for various minor skin conditions, Food preservative, Analytic reagent, Industries, Food & Beverage, Medicine, Pharmaceutical, and Cosmetics & Skincare.
Cosmetics preservatives: Salicylic Acid Cosmetic Grade is mainly used for toilet water, prickly heat water, quinine water and other water cosmetics.
Salicylic Acid Cosmetic Grade is a cosmetic-grade product that, in creams and solutions, can be used topically for treating several skin conditions that involve overgrowth of cells, scaling, calluses, warts, dandruff, etc.
Salicylic Acid Cosmetic Grade is also effective for acne treatment and penetrates the skin to remove damaged cells clogging pores.
Salicylic Acid Cosmetic Grade is widely used as a preservative but also as ingredient in face washes, cleaners and exfoliants.
With an ability to safely help remove the outer layer of skin and dissolve skin debris Salicylic Acid Cosmetic Grade is now found in a wide range of cosmetics and toiletries.
Salicylic Acid Cosmetic Grade is used in various cosmetic formulations as it has antibacterial, anti-ageing, keratolytic, exfoliating, antimycotic and preservative properties.
Salicylic Acid Cosmetic Grade's salts, the salicylates, are used as analgesics.
-Salicylic Acid Cosmetic Grade can be usd as pharmaceutical raw materials.
For the preparation of aspirin, sodium salicylate, salicylamide, analgesic,phenyl salicylate, Xue Fang -67 and other drugs.
Dye industry for the preparation of moxibustion pure yellow, direct brown 3GN,acid chrome yellow and so on.
Salicylic Acid Cosmetic Grade is also used as a rubber vulcanization retarder and disinfectant preservatives
-Salicylic Acid Cosmetic Grade in cosmetics
Which products currently contain salicylic acid? The use of this compound in cosmetics is very common. Salicylic acid is present, among others, in:
*acne toners,
*antibacterial gels and creams,
*exfoliants,
*soaps,
*masks,
*anti-dandruff shampoos.
In cosmetic and pharmaceutical industries, the manufacturers find new applications for Salicylic Acid Cosmetic Grade again and again.
Salicylic Acid Cosmetic Grade is also used in products such as corn plasters, anti-acne zinc pastes with salicylic acid or exfoliating face serums.
Advanced preparations with high concentration of salicylates are also available on the market.
These products are mainly used for a professional local treatments for the face and body.
HOW DOES SALICYLIC ACID COSMETIC GRADE WORK?
Why have people been using Salicylic Acid Cosmetic Grade for more than 150 years?
The reason is that this compound has a very broad range of effects — Salicylic Acid Cosmetic Grade is one of the most effective disinfectants, bactericides, fungicides and regenerating agents.
Facials using Salicylic Acid Cosmetic Grade reduce the amount of sebum and improve the overall condition of the skin.
Salicylic Acid Cosmetic Grade thoroughly exfoliates the skin, facilitating the removal of sick or dead cells.
(However, it is important to note that an excessive amount of Salicylic Acid Cosmetic Grade may cause skin dryness.)
Salicylic Acid Cosmetic Grade can also be used for skin discolouration.
Salicylic Acid Cosmetic Grade's solution, applied in an appropriate quantity, evens-out the skin tone and gradually removes the hyperpigmentation spots.
Moreover, Salicylic Acid Cosmetic Grade can be used on foot skin, facilitating the removal of uncomfortable corns and non-aesthetic, calloused skin.
KEY FEATURES OF SALICYLIC ACID COSMETIC GRADE:
Salicylic Acid Cosmetic Grade is a beta hydroxy acid.
It’s well-known for reducing acne by exfoliating the skin and keeping pores clear.
Salicylic Acid Cosmetic Grade can get deep into your skin to do its job.
This quality is precisely what makes Salicylic Acid Cosmetic Grade such a potent ingredient for targeting acne — especially for blackheads and whiteheads.
Once it penetrates the skin, Salicylic Acid Cosmetic Grade "dissolves skin debris that clogs pores, [acts] as an anti-inflammatory, and also helps red, inflamed pimples and pustules go away faster,.
Salicylic Acid Cosmetic Grade can penetrate so deeply into skin that actually breaks down the connections between skin cells.
Once it has penetrated the skin, the acid part of the molecule can dissolve some of the intracellular 'glue' that holds skin cells together,.
SALICYLIC ACID COSMETIC GRADE AT A GLANCE:
*Also known as beta hydroxy acid (BHA)
*Best known for exfoliating properties
*Oil solubility lets it exfoliate inside pores
*Can help soothe skin
WHAT IS SALICYLIC ACID COSMETIC GRADE USED FOR?
Salicylic Acid Cosmetic Grade is an exfoliating agent that can handle acne very well.
Its complicated structure makes Salicylic Acid Cosmetic Grade more oil-soluble and thus it can penetrate into the skin’s pores.
Face washes with Salicylic Acid Cosmetic Grade or cleansers with salicylic acid are commonly available due to this reason.
Salicylic Acid Cosmetic Grade also works as a hair-conditioning and anti-dandruff agent.
*Skin care:
Salicylic Acid Cosmetic Grade is a potent anti-acne ingredient especially for whiteheads and blackheads.
Salicylic Acid Cosmetic Grade penetrates deeply into the skin, dissolves the skin debris that clogs the pores and is anti-inflammatory.
Blackheads (open plugged pores), whiteheads (closed plugged pores), or pimples (pustules) frequently develop when your hair follicles (pores) become clogged with dead skin cells and oil.
The dead skin cells clogging your pores are removed by the skin-penetrating action of Salicylic Acid Cosmetic Grade.
Salicylic Acid Cosmetic Grade is a keratolytic drug, making it ideal for the most thorough exfoliation
ORIGIN OF SALICYLIC ACID COSMETIC GRADE:
The Kolbe-Schmitt reaction, also known as high pressure and high temperature treatment of sodium phenolate with carbon dioxide, is the process used in the manufacture of sodium salicylate.
Salicylic Acid Cosmetic Grade is produced by acidifying the product with sulfuric acid.
Aspirin (acetylsalicylic acid) or methyl salicylate (oil of wintergreen) can also be hydrolyzed with a potent acid or base to create Salicylic Acid Cosmetic Grade.
WHAT DOES SALICYLIC ACID COSMETIC GRADE DO IN A FORMULATION?
*Antidandruff
*Hair conditioning
*Keratolytic
*Preservative
SAFETY PROFILE OF SALICYLIC ACID COSMETIC GRADE:
According to the Ministry of Health, Labor and Welfare (MHLW) of Japan, Salicylic Acid Cosmetic Grade and its salts as preservatives are restricted to a maximum content of 0.2 g/100 g in all cosmetics.
The Cosmetics Ingredient Review (CIR) panel concluded Salicylic Acid Cosmetic Grade to be safe as used when formulated to avoid skin irritation and when formulated to avoid increasing the skin’s sun sensitivity, or, when increased sun sensitivity would be expected.
Salicylic Acid Cosmetic Grade is currently listed in Annex V (entry 3) of the Cosmetics Regulation (EC) No. 1223/2009 as preservative to be used in all cosmetic products up to a maximum concentration of 0.5% (acid).
The following restriction applies: Not to be used for children under 3 years old, except for shampoos.
Salicylic Acid Cosmetic Grade is also listed in Annex III (entry 98) of the Cosmetics Regulation to be used up to a maximum concentration of 3.0 % for the cosmetic rinse-off hair products and of 2.0% for other products.
Salicylic Acid Cosmetic Grade is not to be used for purposes other than inhibiting the development of micro-organisms in the products.
ALTERNATIVES OF SALICYLIC ACID COSMETIC GRADE:
*BENZOYL PEROXIDE,
*ALLANTOIN,
*GLYCOLIC ACID
BENEFITS OF SALICYLIC ACID COSMETIC GRADE:
*Exfoliates Skin:
Salicylic Acid Cosmetic Grade promotes cell turnover and helps unclog pores, reducing acne and blackheads.
*Reduces Inflammation:
Salicylic Acid Cosmetic Grade soothes irritated skin and reduces redness associated with acne.
*Brightens Complexion:
Salicylic Acid Cosmetic Grade improves skin tone by removing dead skin cells.
*Fights Signs of Aging:
Salicylic Acid Cosmetic Grade helps diminish fine lines and wrinkles by encouraging new skin cell growth.
*Versatile Ingredient:
Salicylic Acid Cosmetic Grade is suitable for various formulations including creams, lotions, masks, and peels.
FUNCTION OF SALICYLIC ACID COSMETIC GRADE:
1.Salicylic Acid Cosmetic Grade is a natural anti-inflammatory .
2 Salicylic Acid Cosmetic Grade can help curing chronic skin diseases such as acne and hemorrhoids.
3.Cosmetics preservatives:
Salicylic Acid Cosmetic Grade is mainly used for toilet water, prickly heat water, water and other water cosmetics.
4.Salicylic Acid Cosmetic Grade also can be usd as raw materials in health care and other industry.
WHERE CAN SALICYLIC ACID COSMETIC GRADE BE FOUND?
Where can salicylic acid be found?
In nature, Salicylic Acid Cosmetic Grade is present in plants.
Salicylic Acid Cosmetic Grade keeps them healthy and protects them from pathogens and pests.
Salicylic Acid Cosmetic Grade also stimulates their growth and improves the life-giving process of photosynthesis.
WHAT THINGS CONTAIN SALICYLIC ACID COSMETIC GRADE?
Salicylates, i.e., the salts and esters of Salicylic Acid Cosmetic Grade, are also found in many products that we use on a daily basis.
Those include, but are not limited to:
*certain vegetables and dried fruits,
*pickled fruits and vegetables,
*mustards,
*wines and other fermented beverages,
*certain fruit juices and concentrates,
*herbs and spices.
Under laboratory conditions, Salicylic Acid Cosmetic Grade can be obtained by the so-called Kolbe–Schmitt reaction using sodium phenoxide and carbon dioxide.
PHYSICAL AND CHEMICAL PROPERTIES OF SALICYLIC ACID COSMETIC GRADE:
What are Salicylic Acid Cosmetic Grade characteristics?
Salicylic Acid Cosmetic Grade is a white or transparent, crystalline and odourless powder.
Salicylic Acid Cosmetic Grade dissolves easily in hot water, ethanol, chloroform and ether.
On the other hand, Salicylic Acid Cosmetic Grade does not dissolve at all or dissolves very poorly in cold water.
The density of Salicylic Acid Cosmetic Grade is 1.443 g/cm³ and its melting point is 159 °C.
Salicylic acid: acceptable concentration
Strongly concentrated Salicylic Acid Cosmetic Grade irritates mucous membranes and may even cause skin burns.
In cosmetics and drugs, appropriate concentrations of it depend on its function in a given product.
Detailed guidance on the maximum concentration of Salicylic Acid Cosmetic Grade is given in the Regulation (EC) No 1223/2009 of 30 November 2009.
According to this regulation, the maximum concentration of Salicylic Acid Cosmetic Grade used as a preservative in the manufacture of cosmetics is 0.5%.
Additionally, acidum salicylicum is not to be used, among others, in cosmetics for children under 3 years of age (except for shampoos).
In certain rinse-off cosmetics, the concentration of Salicylic Acid Cosmetic Grade used as a preservative should not exceed 2–3% (depending on the type of the product and its intended use).
In ready-made and compounded drugs, the concentration of Salicylic Acid Cosmetic Grade solutions ranges from 1% to 10%.
There are also very strong cosmetic preparations available on the market that contain 30–40% of Salicylic Acid Cosmetic Grade — those are most often specialist products used in beauty salons.
SCIENTIFIC FACTS OF SALICYLIC ACID COSMETIC GRADE:
Also known as 2-hydroxybenzoic acid, Salicylic Acid Cosmetic Grade occurs naturally in the bark of the willow tree, Salix alba, and methyl salicylate is present in wintergreen leaves, Gaultheria procumbens, and in sweet birch bark, Betula lenta.
Salicylic Acid Cosmetic Grade is probably best known as a compound that is chemically similar but not identical to the active component of aspirin (acetylsalicylic acid).
CHEMISTRY OF SALICYLIC ACID COSMETIC GRADE:
Salicylic Acid Cosmetic Grade is the ortho isomer of monohydroxybenzoic acid.
Salicylic Acid Cosmetic Grade is commonly referred to as a beta hydroxy acid due to the location of its hydroxyl (–OH) group, which is two carbons away from the carboxylic acid (–COOH) group.
Salicylic Acid Cosmetic Grade is a relatively small molecule with the chemical formula C7H6O3, corresponding to a molecular weight of 138.12 g/mol.
Salicylic Acid Cosmetic Grade is more acidic than most organic acids; for example, the pKa of Salicylic Acid Cosmetic Grade is 3.0 whereas the pKa of the unsubstituted benzoic acid is 4.2.
This increased acid strength is due to the location of the electron-withdrawing –OH group on its aromatic ring, which promotes dissociation of the –COOH group at lower pH values.
Salicylic Acid Cosmetic Grade is a natural compound that can be derived from various species of plants, most notably from trees of the genera Salix (willow) and Populus (poplar).
Although Salicylic Acid Cosmetic Grade can occur naturally as an organic acid, SA itself is rarely found in nature.
Instead, most plant extracts yield Salicylic Acid Cosmetic Grade in the form of organic compounds that are readily converted to SA via metabolism, e.g., upon ingestion, or via mild chemical reactions such as hydrolysis and/or oxidation.
Examples of such naturally occurring Salicylic Acid Cosmetic Grade precursors include the glucoside of salicyl alcohol, known as salicin, and the methyl ester of SA, methyl salicylate.
MANUFACTURE OF SALICYLIC ACID COSMETIC GRADE:
Salicylic Acid Cosmetic Grade is synthesized commercially via the Kolbe-Schmitt reaction.
The key feedstock for this process is phenol, a commodity petrochemical derived from benzene.
During this process, phenol is first reacted with sodium hydroxide (NaOH) to yield sodium phenate.
The sodium phenate is heated until no water is present, then reacted with carbon dioxide (CO2) under pressure at 100–160°C to form crude sodium salicylate.
By-products that can form during this reaction include 4-hydroxybenzoic acid and 4-hydroxyisophthalic acid.
The crude reactor product is then dissolved in water, treated with processing aids such as activated carbon to remove colored impurities, and filtered.
Salicylic Acid Cosmetic Grade is isolated from this solution by acidification of the sodium salicylate with a mineral acid, e.g., sulfuric acid, which causes the SA to precipitate as a crystalline solid.
Salicylic Acid Cosmetic Grade is collected via filtration, washed and dried; to obtain high-purity SA, the compound is typically purified further via sublimation.
PROPERTIES OF SALICYLIC ACID COSMETIC GRADE:
Salicylic Acid Cosmetic Grade typically is supplied as a fluffy white crystalline powder or as fine needles.
Synthetic Salicylic Acid Cosmetic Grade is white and odorless whereas natural SA, derived from the hydrolysis of methyl salicylate, may have a slight pink or yellow tint and a faint wintergreen-like odor.
The USP-grade Salicylic Acid Cosmetic Grade employed as an active ingredient for OTC drug applications must be minimally 99.5% pure SA.
Trace impurities may include, at ppm levels, the organic compounds 4-hydroxybenzoic acid, 4-hydroxyisophthalic acid and phenol.
Crystals of pure Salicylic Acid Cosmetic Grade melt at 159°C.
In addition, SA is sparingly soluble in water (0.2% w/w at 20°C) but it is readily soluble in polar organic solvents such as ethanol and acetone.
Salicylic Acid Cosmetic Grade absorbs light in the UVB range with a peak absorbance at ca. 300 nm, and is a weakly fluorescent molecule.
This latter attribute is especially useful for quantitative detection of Salicylic Acid Cosmetic Grade deposition and retention on the skin via fluorescence spectroscopy.
FORMULATION OF SALICYLIC ACID COSMETIC GRADE:
Perhaps the most critical formulation guideline for developing Salicylic Acid Cosmetic Grade-containing products is that SA must be kept in its acid form to ensure efficacy.
Recall that Salicylic Acid Cosmetic Grade has a pKa value of 3.0; thus, at pH 3.0, it will be 50% ionized—meaning that only half of the SA in a formula at a pH of 3.0 is in its active form.
Thus, Salicylic Acid Cosmetic Grade must be formulated into low pH systems, typically below pH 4.0, which requires formulators to omit ingredients that are susceptible to degradation in acidic conditions.
For example, in Salicylic Acid Cosmetic Grade face washes, alpha olefin sulfonates such as sodium C14–16 olefin sulfonate are typically employed as anionic surfactants in place of alkyl ether sulfates, e.g., sodium laureth sulfate, because the latter are subject to hydrolysis at low pH levels.
SALICYLIC ACID COSMETIC GRADE MARKET INSIGHTS:
Cosmetics Grade Salicylic Acid Market size was valued at USD 3.10 Billion in 2023 and is projected to reach USD 6.6 Billion by 2030, growing at a CAGR of 8.79% during the forecast period 2024-2030.
The Salicylic Acid Cosmetic Grade Market has been steadily growing, driven by an increasing demand for effective skincare solutions.
Salicylic Acid Cosmetic Grade, a beta-hydroxy acid, is renowned for its ability to penetrate pores, exfoliate dead skin cells, and reduce inflammation.
Salicylic Acid Cosmetic Grade is primarily used in various cosmetic products such as cleansers, toners, and spot treatments, making it a staple in the beauty industry.
With the rise of skincare awareness and the desire for healthier skin, consumers are gravitating towards products containing Salicylic Acid Cosmetic Grade for its proven efficacy against acne and other skin conditions.
Market dynamics are influenced by several factors, including evolving consumer preferences, advancements in formulation technology, and heightened awareness of skin health.
As people increasingly seek out products that promise clear and radiant skin, the role of Salicylic Acid Cosmetic Grade becomes even more significant.
The surge in online shopping and the proliferation of beauty influencers have also catalyzed the demand for cosmetics containing Salicylic Acid Cosmetic
Grade, as consumers are more exposed to information regarding effective skincare routines and ingredients.
This digital landscape is reshaping how brands approach their marketing strategies and product offerings.
GLOBAL SALICYLIC ACID COSMETIC GRADE MARKET DRIVERS:
Global Cosmetics Grade Salicylic Acid Market Drivers
The growth and development of the Salicylic Acid Cosmetic Grade Market is attributed to certain main market drivers.
These factors have a big impact on how integrated gas systems are demanded and adopted in different sectors.
Several of the major market forces are as follows:
*Growing Consumer Need for Skincare Goods:
Consumer awareness and demand for skincare products are driving expansion in the cosmetics business.
Salicylic Acid Cosmetic Grade is a common component in many skincare formulas because of its ability to exfoliate skin and combat acne.
*Increasing Frequency of Skin Problems:
Because salicylic acid is frequently used in cosmetics, the demand for Salicylic Acid Cosmetic Grade may be driven by the incidence of skin-related conditions like psoriasis and acne.
*Expansion of the Cosmetic Sector:
The demand for Salicylic Acid Cosmetic Grade and other cosmetic components may rise as a result of the cosmetics industry’s general growth and expansion.
This growth could be attributed to growing disposable income and emerging markets.
*Novel Approaches to Formulations:
Continued research and development efforts to provide fresh and inventive cosmetic formulas can result in the addition of Salicylic Acid Cosmetic Grade to new goods, stimulating consumer demand.
*Preference for Organic and Natural Substances:
The market for Salicylic Acid Cosmetic Grade generated from natural sources may expand as customers look more and more for natural and organic products.
In response, manufacturers might create formulas that suit these inclinations.
*Growth of E-Commerce:
A larger customer base can now easily obtain beauty products thanks to the growth of e-commerce platforms.
This may help the market for Salicylic Acid Cosmetic Grade suitable for cosmetics to increase.
*Regulatory Aspects to Take into Account:
The market may be impacted by modifications to standards or laws pertaining to ingredients used in cosmetics.
The market for particular compounds, such as Salicylic Acid Cosmetic Grade, may be shaped by adherence to safety standards and regulatory compliance.
*Partnerships & Cooperations:
Partnerships with academic institutions and ingredient suppliers, in addition to collaborations between cosmetic firms, can spur innovation and impact the Salicylic Acid Cosmetic Grade market for cosmetics.
PHYSICAL and CHEMICAL PROPERTIES of SALICYLIC ACID COSMETIC GRADE:
Boiling Point: 211°C at 20mmHg
Melting Point: 158-161°C
pH: 2.4
Solubility: Soluble in water, acetone, ether, benzene
Appearance: White crystalline powder
Purity: ≥ 99%
Molecular Formula: C7H6O3
Molecular Weight: 138.12 g/mol
Melting Point: 158-161°C
Solubility: Soluble in ethanol, partially soluble in water
pH (1% solution): 2.4 – 2.8
Compatibility: Compatible with most ingredients used in personal care formulations.
Appearance: White powder
Odor: Odorless
Solubility: Soluble in water (≥5%)
pH (5%): 3.0 - 5.5
Recommended Rate: 0.5-1.0%
Molecular Weight: 138.12 g/mol
XLogP3: 2.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 138.031694049 Da
Monoisotopic Mass: 138.031694049 Da
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 133
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Formula : C7H6O3
Molecular weight : 138,12 g/mol
CAS-No. : 69-72-7
EC-No. : 200-712-3
Physical state: powdercrystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 158 - 160 °C
Initial boiling point and boiling range: 211 °C at 27 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Lower explosion limit: 1,1 %(V)
Flash point 157 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 2,4 at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water:
log Pow: 2,25 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: 1 hPa at 114 °C
Density: 1,44 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Chemical Name : 2 – Hydroxybenzoic Acid
Molecular Formula : C7H6O3
Molecular Weight : 138.1
Description : White / colourless, crystalline powder / acicular crystals
CAS No. : 69-72-7
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid: Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C
storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability: Stable.
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC Name: 2-hydroxybenzoic acid
Molecular Weight: 138.12
Molecular Formula: C7H6O3
Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)O
InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
Boiling Point: 211 ℃ (20 mmHg)
Melting Point: 154-156 ℃
Flash Point: 157ºC
Purity: > 98 %
Density: 1.44 g/cm3
Solubility: Solubility (weight percent):
carbon tetrachloride 0.262 (25 °C);
benzene 0.775 (25 °C); propanol 27.36 (21 °C);
absolute ethanol 34.87 (21 °C); acetone 396 (23 °C)
Appearance: White poder
Storage: Store at RT.
EINECS: 200-712-3
Hazard Codes: Xn
HS Code: 2918211000
Log P: 1.09040
MDL: MFCD00002439
pH: pH of saturated solution: 2.4
PSA: 57.53
Quality Standard: Enterprise Standard
Refractive Index: 1.565
Risk Statements: R22; R36/37/38; R41
RTECS: VO0525000
Safety Statements: S26-S37/39
Stability: Stable.
Vapor Density: 4.8
Vapor Pressure: 1 mm Hg ( 114 °C)
Odour: Almost Odourless.
Melting Range: 158.5°C to 161.0°C.
Appearance of Solution/
Clarity & Colour of Solution: Passes test as per B.P./I.P.
Heavy Metals: 20 ppm (max)
Sulphated Ash/Residue on Ignition: 0.1% w/w (I.P./B.P.Limit) / 0.05% w/w (U.S.P. Limit)
Chloride: 125 ppm (max.) I.P./100 ppm (max.) B.P.
Sulphate: 0.02% (max.) I.P./140 ppm U.S.P.
Related Substance: Complies with the B.P. test.
Loss of Drying: 0.5% (max.) B.P.
Iron: 2 ppm (max.) I.P.
Molecular Weight: 138.12 g/mol
XLogP3: 2.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 138.031694049 g/mol
Monoisotopic Mass: 138.031694049 g/mol
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 133
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH
Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
Chemical formula: C7H6O3
Molar mass: 138.122 g/mol
Appearance: Colorless to white crystals
Odor: Odorless
Density: 1.443 g/cm3 (20 °C)
Melting point: 158.6 °C (317.5 °F; 431.8 K)
Boiling point: 211 °C (412 °F; 484 K) at 20 mmHg
Sublimation conditions: Sublimes at 76 °C
Solubility in water:
1.24 g/L (0 °C)
2.48 g/L (25 °C)
4.14 g/L (40 °C)
17.41 g/L (75 °C)
77.79 g/L (100 °C)
Solubility: Soluble in ether, CCl4, benzene, propanol,
acetone, ethanol, oil of turpentine, toluene
Solubility in benzene:
0.46 g/100 g (11.7 °C)
0.775 g/100 g (25 °C)
0.991 g/100 g (30.5 °C)
2.38 g/100 g (49.4 °C)
4.4 g/100 g (64.2 °C)
Solubility in chloroform:
2.22 g/100 mL (25 °C)
2.31 g/100 mL (30.5 °C)
Solubility in methanol:
40.67 g/100 g (−3 °C)
62.48 g/100 g (21 °C)
Solubility in olive oil: 2.43 g/100 g (23 °C)
Solubility in acetone: 39.6 g/100 g (23 °C)
log P: 2.26
Vapor pressure: 10.93 mPa
Acidity (pKa):
2.97 (25 °C)
13.82 (20 °C)
UV-vis (λmax): 210 nm, 234 nm, 303 nm (4 mg/dL in ethanol)
Magnetic susceptibility (χ): −72.23·10−6 cm3/mol
Refractive index (nD): 1.565 (20 °C)
Dipole moment: 2.65 D
Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −589.9 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): -3.025 MJ/mol
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C
storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability:: Stable. S
ubstances to be avoided include oxidizing agents, strong bases, iodine, fluorine.
Sensitive to light.
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC: SALICYLICACID
CAS Number: 69-72-7
Molecular Weight: 138.122
Formula: C7H6O3
SMILES: OC(=O)C1=C(O)C=CC=C1
Preferred IUPAC Name: 2-HYDROXYBENZOIC ACID
InChIKey: InChIKey=YGSDEFSMJLZEOE-UHFFFAOYSA-N
Melting Point: 158°C
Color: White
pH: 3.6
Boiling Point: 211°C
Formula Weight: 138.12g/mol
Vapor Pressure: 0.3mbar 95
Physical Form: Solid
CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH
Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
CAS number: 69-72-7
Weight Average: 138.1207
Monoisotopic: 138.031694058
InChI Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N
InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
IUPAC Name: 2-hydroxybenzoic acid
Traditional IUPAC Name: salicylic
Chemical Formula: C7H6O3
SMILES: OC(=O)C1=CC=CC=C1O
Appearance: white powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 158.00 to 161.00 °C. @ 760.00 mm Hg
Boiling Point: 211.00 °C. @ 20.00 mm Hg
Boiling Point: 336.00 to 337.00 °C. @ 760.00 mm Hg
Vapor Pressure: 1.000000 mmHg @ 114.00 °C.
Vapor Density: 4.8 ( Air = 1 )
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 2.260
Soluble in: alcohol
water, 3808 mg/L @ 25 °C (est)
water, 2240 mg/L @ 25 °C (exp)
FIRST AID MEASURES of SALICYLIC ACID COSMETIC GRADE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of SALICYLIC ACID COSMETIC GRADE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of SALICYLIC ACID COSMETIC GRADE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of SALICYLIC ACID COSMETIC GRADE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of SALICYLIC ACID COSMETIC GRADE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of SALICYLIC ACID COSMETIC GRADE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available