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DESCRIPTION:
Salvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products.
Salvia Miltiorrhiza Root Extract is not an approved drug.
Salvia miltiorrhiza (Chinese: 丹參; pinyin: dānshēn), also known as red sage, redroot sage, Chinese sage, or danshen, is a perennial plant in the genus Salvia, highly valued for its roots in traditional Chinese medicine.
CAS Number(s) : 90106-50-6
EINECS number(s) : 290-273-4
Native to China and Japan, it grows at 90 to 1,200 m (300 to 3,940 ft) elevation, preferring grassy places in forests, hillsides, and along stream banks.
The specific epithet miltiorrhiza means "red ochre root".
SYNONYMS OF SALVIA MILTIORRHIZA ROOT EXTRACT:
Salvia Miltiorrhiza Root,Chinese Red Root Salvia Root Extract
CHEMICAL CONSTITUENTS:
Chemical compounds isolated from Salvia miltiorrhiza include salvianolic acid (or salvianolic acid B),[3][4] dihydrotanshinone, miltirone,[5] tanshinone I, and tanshinone IIA.
Tanshinone IIA is one of the most abundant constituents of the root of Salvia miltiorrhiza.
S. miltiorrhiza is a deciduous perennial with branching stems that are 30 to 60 cm (0.98 to 1.97 ft) tall, with widely spaced leaves that are both simple and divided.
The 30 cm (0.98 ft) inflorescences are covered with hairs and sticky glands.
Flowers grow in whorls, with light purple to lavender blue corollas that are approximately 2.5 cm (0.082 ft) long, with a dark purple calyx.
Salvia miltiorrhiza prefers well-drained soil, with about half a day of sunlight.
Salvia Miltiorrhiza Root Extract is hardy to approximately −10 °C (14 °F).[9]
Most Salvia seeds have a higher germination rate when exposed to light, though it is not required
Drug interactions:
Danshen may potentiate the effects of the anticoagulation drug warfarin, possibly causing bleeding complications.
Other adverse effects may include allergic reactions, dizziness, headache, or gastrointestinal upset.[6]
Traditional Chinese medicine:
Alone or combined with other Chinese herbal medicines, Salvia miltiorrhiza has been used in China and, to a lesser extent, in other countries as a treatment for various cardiovascular and cerebrovascular diseases.
A 2007 Cochrane review of the use of danshen for acute ischaemic stroke found that the quality of evidence was poor, and there was no evidence of benefit.
Similarly, a 2008 Cochrane meta-analysis found the clinical trials on danshen were low in quality, and were insufficient to make any judgment about its efficacy for people with heart attack.[14]
Meta-analyses of oral and injectable forms of danshen in people with angina concluded that the effects of the treatment were inconclusive because the studies were low in quality and the conclusions were not based on strong evidence
This Chinese plant, Chinese Red Root Salvia (Salvia Miltiorrhiza), not to be confused with the more common Salvia Officinalis or Sage herb, has been used to increase metabolism, immunity, and blood circulation, as well as to treat coronary heart disease and ulcers.
Salvia Miltiorrhiza Root Extract's sedative, tranquilizing characteristics are used to relieve irritability, restlessness, and insomnia.
Salvia Miltiorrhiza Root Extract is a light to medium amber liquid with a characteristic odor.
Salvia Miltiorrhiza Root Extract is soluble in any proportion in water, and the solution pH range is 4.0 - 6.5 at 25 °C.
Incorporated in skin care applications, Salvia Miltiorrhiza Root Extract is known to promote the repair and regeneration of skin tissue.
The extract of the Chinese Red Root can be used in skin and hair care products such as creams, lotions, and bath products.
The usage level is 5 - 10%.
PROPERTIES OF SALVIA MILTIORRHIZA ROOT EXTRACT:
Scientific classificationEdit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Lamiales
Family: Lamiaceae
Genus: Salvia
Species: S. miltiorrhiza
Binomial name
Salvia miltiorrhiza
Product Name Salvia Root Extract Powder/danshen extract
Raw Material Salvia Root
Color Red Brown Powder
Application fields Food Supplement
Active Ingredient Total Tanshinones 10% 20%
Part Used Root
Shelf Life 24 Months
Sample Freely Provided
Name of the plant
Chinese Sage; Chinese Salvia; Redroot Sage
Used plant parts
Roots
Type of preparation
Extract (solvent extract)
Function(s) of this ingredient in cosmetic products
SKIN CONDITIONING
Maintains the skin in good condition
Origin
plant
Belongs to the following substance groups
Ingredients for skincare
Functions
Regeneration booster
Soothing
Skin conditioning
Hair conditioning
CAS Number(s)
90106-50-6
EINECS number(s)
290-273-4
FDA UNII
1693AM5SBN
APPLICATIONS OF SALVIA MILTIORRHIZA ROOT EXTRACT:
1.Salvia miltiorrhiza Extract applied in the cosmetic field, making skin more tender and firm.
2.Salvia miltiorrhiza Extract applied in the health care field .
3. Salvia miltiorrhiza Extract applied in the food additives field.
4.Salvia miltiorrhiza Extract applied in the Health products field.
SAFETY INFORMATION ABOUT SALVIA MILTIORRHIZA ROOT EXTRACT
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.
