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Sarcosyl, is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Sarcosyl is a trade name for sodium lauroyl sarcosinate, a surfactant derived from sarcosine, an amino acid derivative.
Sarcosyl is commonly used in various applications due to its mild nature, excellent foaming properties, and ability to reduce surface tension.
CAS Number: 137-16-6
Molecular Formula: C15H28NO3.Na
Molecular Weight: 293.38
EINECS Number: 205-281-5
Synonyms: 137-16-6, N-Lauroylsarcosine sodium salt, Sodium lauroylsarcosinate, Sodium N-lauroylsarcosinate, Sarcosyl NL, Sarcosyl, Gardol, Sodium lauroyl sarcosinate, Compound 105, Medialan LL-99, Sarcosyl, Caswell No. 778B, Sodium N-dodecanoyl-N-methylglycinate, N-Lauroylsarcosine, sodium, Lauroylsarcosine sodium salt, Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt, MFCD00042728, Sarcosyl NL, N-Lauroylsarcosine, sodium salt, Maprosyl 30, Hamposyl L-30, Sarcosyl NL 30, Sarcosyl NL 30, Sarcosyl NL 35, Sarcosyl NL 97, Sarcosyl NL 100, EINECS 205-281-5, Sodium lauroylsarcosine, EPA Pesticide Chemical Code 000174, NSC 117874, N-Dodecanoyl-N-methylglycine sodium salt, Sodium N-lauroylsarcosine, UNII-632GS99618, Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1), GARDOL [MI], MEDIALAN LL-33, sodium 2-(N-methyldodecanamido)acetate, sodium lauroyl sarcosine, Lauroylsarcosine (sodium), Sarcosine, N-lauroyl-, sodium salt, DTXSID0027066, N-Methyl-N-(1-oxododecyl)glycine, sodium salt, EC 205-281-5, N-Dodecanoyl-N-methylglycine, sodium salt, NSC-117874, sodium [dodecanoyl(methyl)amino]acetate, SODIUM LAUROYL SARCOSINATE [II], SODIUM LAUROYL SARCOSINATE [VANDF], sodium;2-[dodecanoyl(methyl)amino]acetate, SODIUM LAUROYL SARCOSINATE [USP-RS], 632GS99618, Sarcosyl NL-30, Sarcosyl NL-100, Sodium N-Dodecanoylsarcosinate, N-Dodecanoylsarcosine Sodium Salt, Lauroylsarcosine (sodium salt), SODIUM LAUROYL SARCOSINATE (II), SODIUM LAUROYL SARCOSINATE (USP-RS), n-Lauroylsarcosine sodium salt hydrate, SODIUM N-LAUROYL SARCOSINATE, n-lauryl sarcosine sodium salt, 17-((Trimethylsilyl)ethynyl)-17-((trimethylsilyl)oxy) Gestodene, Hamposyl L30, Medialan LL99, n-lauroyl sarcosine, n-lauroylsarcosinate, (8R,9S,10R,13S,14S,17S)-13-Ethyl-17-((trimethylsilyl)ethynyl)-17-((trimethylsilyl)oxy)-6,7,8,9,10,11,12,13,14,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, Sodium Nlauroylsarcosine, starbld0009501, n-lauroylsarcosine sodium, NLauroylsarcosine, sodium, Sodium Nlauroylsarcosinate, N-Methyl-N-(1-oxododecyl)glycine sodium salt, SCHEMBL23451, Lauroylsarcosine, Sodium Salt, NLauroylsarcosine, sodium salt, Sodium lauroyl sarcosinic acid, DTXCID907066, N-Methyl-N-(1-oxododecyl)glycine sodium salt (1:1), CHEMBL1903482, Sarcosine, Nlauroyl, sodium salt, Tox21_202996, NDodecanoylNmethylglycine, sodium salt, AKOS015901704, NCGC00164323-01, NCGC00260541-01, Sarcosine, Nlauroyl, sodium salt (8CI), SODIUM LAUROYL SARCOSINATE [INCI], AS-81025, CAS-137-16-6, NMethylN(1oxododecyl)glycine, sodium salt, DB-042377, HY-125920, Sarcosine, N-lauroyl-, sodium salt (8CI), CS-0103267, Glycine, NmethylN(1oxododecyl), sodium salt, L0019, NS00078145, S0597, E81236, Q309660, W-108241, 60318-46-9n-methyl-n-(1-oxododecyl)glycine sodium salt;N-LAURYL SARCOSINE, SODIUM SALT;N-LAUROYLSARCOSINE NA-SALT;N-LAUROYLSARCOSINE SODIUM SALT;N-LAUROYLSARCOSINE SODIUM SALT HYDRATE;GARDOL;LAUROYLSARCOSINE, SODIUM SALT;N-Methylglycinol
Sarcosyl is an anionic surfactant with an ability to denature proteins.
Due to its microbicidal property, Sarcosyl is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).
Sarcosyl is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.
Sarcosyl is an anionic detergent used for cell lysis during the extraction of RNA.
Sarcosyl is also suitable for the solubilization of membrane protein.
Sarcosyl is an ionic detergent that is reportedly an inhibitor of hexokinase.
Sarcosyl Solution is used as a 10% Sterile Solution for cell lysis in RNA purication protocols and membrane solubilization.
Sarcosyl is used as a detergent, foaming agent, and antienzyme for dentifrices; Permitted for use as an inert ingredient in non-food pesticide products.
These surfactants have good foaming properties, also at a higher pH range.
Amino-acid surfactants have good tolerance to highly alkaline environment and may be used as aids in foam formation, even at high pH values that in case of other surfactants decrease foaming eciency.
Sarcosyl is an ionic surfactant derived from sarcosine, used as a foaming and cleansing agent in shampoo, shaving foam and foam wash products.
In molecular biology experiments, Sarcosyl is used to inhibit the initiation of DNA transcription.
Sarcosyl is widely used in various industries (cosmetics, detergents, household and industrial cleaning, agro-chemicals, textiles processing).
Sarcosyl is an ionic detergent used to denature proteins in hybridization, nucleic acid purication, and electrophoresis.
Sarcosyl is used in concentrated salt solutions as a detergent because SDS is insoluble in concentrated salt solutions.
Sarcosyl (Anionic) used to solubilise proteins.
Hydrophobic membrane proteins are suited to more non ionic detergents.
Sarcosyl is used mild baby shampoo, facial cleansers, liquid soaps, shaving product or toothpaste.
Sarcosyl is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Sarcosyl: antistatic agents, cleansing agents, foaming agents, hair conditioning, skin conditioning, surfactants, surfactant - emulsifying, and viscosity controlling agents.
This surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH.
The carboxylate has a pKa of about 3.6 and is therefore negatively charged in solutions of pH greater than about 5.5.
pH-sensitive vesicles can be prepared using this surfactant with another cationic or water-insoluble amphiphiles such as 1-decanol.
Sarcosyl is quite mild with superior foaming capacity, and its skin feeling is mild, smooth and comfortable.
Sarcosyl, Sulfate-free anionic surfactant, providing dense lather and aiding foam stability.
Sarcosyl Can be used in clear formulations and is stable over a wide pH range. Ideal co-surfactant.
Foam stability is better in the weakly acid than in the alkaline pH range.
Sarcosyl is excellent foaming power in electrolyte-containing solutions.
Sarcosyl is soluble in water in any ratio and forms clear solutions.
Sarcosyl is the salt of lauroyl sarcosine (produced by the breakdown of creatine or caeine), a modied fatty acid.
Sarcosyl is very mild, but also very eective.
Sarcosyl, FDA approved as an indirect food additive, and CIR approved when used in rinse-o products, or in leave-on products at concentrations of 5% or less.
Addition of an mixture of equal parts of Sarcosyl and the non-ionic surfactant sorbitan monolaurate (S20) to a buffered water: ethanol solution led to the formation of micelle-like aggregates, even though neither surfactant formed micelles when present alone.
Such aggregates can help carry other small molecules, such as drugs, through the skin.
Sarcosyl can be combined with other anionic surfactants commonly used in cosmetics and improves skin compatibility.
Sarcosyl is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sarcosyl has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
Sarcosyl also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
Sarcosyl is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.
Sarcosyl is an anionic specialty surfactant.
Sarcosyl is particularly mild, and is suitable for sensitive skin and sensitive areas.
Sarcosyl improves foam and thickening properties of formulations.
Sarcosyl is Suitable for shampoos, foam baths, shower gels, syndet bars, detergents, creamy shower products, and baby products.
Sarcosyl is A powerful anionic surfactant that confers mild detergency, excellent foaming and lathering characteristics.
Sarcosyl Displays synergy with other detergents.
Sarcosyl is Wetting agent.
Sarcosyl is Enzyme inhibitor in oral care.
Sarcosyl is Corrosion inhibitor.
Produces a creamy, stable foam even in the presence of oils.
Has a mild cleansing action that doesn’t strip natural oils from the skin or hair.
Compatible with other surfactants and ingredients.
Improves foam stability and spreadability, making it ideal for sulfate-free formulations.
Reduces irritation compared to harsher surfactants like sodium lauryl sulfate (SLS).
Sarcosyl is used in facial and body cleansers for sensitive skin due to its mildness.
Provides emulsification and moisturization benefits.
Enhances cleaning efficiency and provides foaming action in toothpastes and mouthwashes.
Sarcosyl helps in emulsifying ingredients like oils and flavor compounds.
Sarcosyl, also known as Sodium Lauroyl Sarcosinate, is a surfactant derived from vegetable fatty acids and Sarcosine (natural amines, an amino acid found naturally in the body).
Sarcosyl is often used as a secondary surfactant to increase and improve lather in body gels, but Sarcosyl also has great benets in shampoos or conditioners as Sarcosyl is antistatic and improves hair exibility.
Sarcosyl is a mild yet powerful hypoallergenic, non-irritating surfactant with excellent synergistic eect with other surfactants and exceptional creamy foaming properties.
Sarcosyl Reduces irritation and oers moisture.
Sarcosyl is Suitable Vegan, its origin is vegetable and it is Biodegradable.
Sarcosyl is derived from sarcosine, a natural amino acid found in the human body and just about every type of biological material from animals to plants.
Soluble in water and compatible with a wide range of pH levels (acidic to neutral environments preferred).
Melting point: 46 °C
Density: 1.033 g/mL at 20 °C
vapor pressure: 0.02 hPa (20 °C)
RTECS: MC0598960
Flash point: 267℃
storage temp.: room temp
solubility: H2O: 1 M at 20 °C, clear, colorless
form: Powder
Specific Gravity: 1.03 (20/4℃)
color: White
Odor: at 100.00?%. bland
PH: 7.0-9.0 (25℃, 1M in H2O)
Water Solubility: Soluble in water (293 g/L).
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.06
Merck: 14,4368
BRN: 5322974
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: 0.37
Sarcosyl is a detergent that is structurally related to SDS, except that Sarcosyl has an additional polar and rigid peptide bond linkage within the hydrophobic backbone.
Such rigidity added to the N-terminus of the hydrophobic chain could lead to a decrease in Sarcosyl's ability to be inserted freely into hydrophobic membrane bilayers and proteins.
This could explain why Sarcosyl is milder than SDS in its ability to denature and disrupt membrane and protein structures.
Because of a similar dierence in side-chain structure, the bile acid detergent CHAPS is rendered milder than the strongly denaturing sodium cholate, which inactivates integral membrane proteins, such as the serotonin 1A receptor.
Sarcosyl is mild, biodegradable anionic surfactants derived from fatty acids and sarcosine (amino acid).
These compounds features lather building and resistance to sebum delathering in cleaners, polymers, industrial chemicals, petroleum and lubricant products.
As Sarcosyl has good biodegrability, it is in accordance with the requirement of environmental protection.
Sarcosyl is an anionic surfactant from the group of amino-acid surfactants with.
Sarcosyl is produced basing on biomimetics, which are raw materials imitating naturally occurring chemical compounds and fatty acids (raw materials of plant origin).
Sarcosyl is provided as an aqueous solution with the active substance content of approximately 30%.
Sarcosyl, A mild, biodegradable cleansing agent that is also a very good team-player next to other cleaning agents.
Sarcosyl is known for its good foam-boosing abilities while improving the mildness of the formula.
Sarcosyl belongs to anionic surfactant of amino acid category.
Sarcosyl is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sarcosyl is a high foam, eco-friendly surfactant.
It has good chlorine stability with anti-corrosion properties.
This surfactant has excellent ocular tolerance and gentleness.
Sarcosyl is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sarcosyl has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
This ingredient also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Sarcosyl is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.
Sarcosyl is a natural ingredient that is derived from coconuts.
However, it can also be made synthetically.
Sarcosyl is used in laundry detergents and dishwashing liquids for its ability to break down grease and oils while being gentler on skin.
Effective in hard water conditions due to its calcium and magnesium ion tolerance.
Sarcosyl improves the solubility and stability of hydrophobic drugs.
Demonstrates mild antimicrobial action, useful in formulations like medicated shampoos or dental products.
Sometimes included as an emulsifying or dispersing agent, though usage is limited in this area compared to other surfactants.
Frequently used as a reagent in molecular biology and protein purification due to its ability to solubilize membranes and denature proteins gently.
Sarcosyl was sold as a special ingredient called "Gardol" in Colgate "Dental Cream", as toothpaste was then called, during the 1950s through the mid-1960s in the US and the mid-1970s in France.
Sarcosyls current use as a preventive dentifrice is in Arm & Hammer Baking Soda Toothpaste, a Church & Dwight product, where it is used as a surfactant.
Sarcosyl is used Anionic surfactant, especially resistant to chlorine.
Sarcosyl is used as a secondary surfactant in cosmetics-detergent due to its foam-increasing feature.
Sarcosyl is used Consistent bleach (2-5%), Detergent and Cosmetics (3-10%), Baby shampoo (3-8%).
Sarcosyl can reduce the irritation caused by the residue of traditional surfactants on the skin with it's good compatibility properties.
Sarcosyl and sodium lauroyl sarcosinate are surfactants used as ingredients in shampoos, baby and face cleansers, bath lotions and toothpastes;
Sarcosyl is used in household and professional detergents for hard surface cleaning, in particular for car cleaning, too.
For the manufacture of hair shampoos and body cleansing products Sarcosyl is often best combined as mild Co-surfactant with alkyl ether sulphates.
Uses:
Sarcosyl is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase.
It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).
It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).
Sarcosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sarcosyl is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes.
It can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
The typical usage levels range from 1-5% on an active basis.
Sarcosyl is used in foaming and emulsifying agents in skincare products.
Used in detergents and cleaning agents due to its grease-cutting and foaming properties.
Sometimes used as an excipient in formulations for its stabilizing and wetting properties.
Sarcosyl is used in facial cleansers, body washes, and baby products as a gentle surfactant.
Offers effective cleansing without stripping natural oils, making it suitable for sensitive skin.
Common in sulfate-free and low-irritant shampoos for mild cleansing and rich foaming.
Sarcosyl found in oral care products for its cleaning, foaming, and emulsifying properties.
Compatible with active ingredients like fluoride, enhancing their stability.
Sarcosyl is used in shaving creams and gels to create stable, creamy foam that aids in a smooth shave.
Enhances product spreadability and provides emulsification in sunscreen and hydrating lotions.
Sarcosyl added to laundry detergents and dishwashing liquids for grease-cutting and soil-removal properties.
Performs well in hard water due to calcium and magnesium ion tolerance.
Sarcosyl is used in sprays and liquid cleaners for kitchen and bathroom surfaces, offering efficient degreasing without damaging materials.
Sarcosyl plays an important role in household detergents and dishwashing liquids, where its grease-cutting and soil-removal capabilities are highly valued.
Its compatibility with both hard and soft water ensures its effectiveness in various water conditions, making it ideal for use in areas with varying water hardness.
Surface cleaners for kitchens and bathrooms frequently contain Sarcosyl because it provides a balance between powerful cleaning action and material safety, preventing damage to delicate surfaces while effectively removing dirt, grime, and grease.
The ability to create stable formulations also makes Sarcosyl a reliable component in industrial cleaning products designed for more rigorous applications.
Sarcosyl finds significant use in molecular biology laboratories, where it is employed as a solubilizing agent to break down cellular membranes and solubilize proteins for various types of analyses.
Sarcosyls role in applications such as SDS-PAGE and other electrophoresis methods is well-documented, as it helps denature proteins while maintaining their solubility for accurate analysis.
In protein purification protocols, Sarcosyl is frequently chosen for its ability to gently disrupt cell membranes without completely denaturing target proteins, preserving their activity for downstream applications.
Sarcosyl is also employed in specialty products like firefighting foams, where its ability to generate stable, long-lasting foam is crucial for smothering flames and cooling down surfaces.
Additionally, its mildness and compatibility with other ingredients make it a preferred choice in niche cosmetic and industrial formulations that require a balance of efficacy and gentleness.
In advanced skincare products, Sarcosyl stabilizes complex emulsions, ensuring that active ingredients are uniformly dispersed and effectively delivered to the skin.
Helps in emulsifying and stabilizing creams and ointments.
Sarcosyl is used in molecular biology to solubilize proteins and membranes for analysis or purification.
Acts as a gentle detergent in SDS-PAGE and other electrophoresis applications.
Occasionally used in food-grade applications to stabilize emulsions in sauces, creams, and beverages.
Aids in dyeing and finishing processes by improving wetting and penetration of chemicals.
Sarcosyl is used as a surfactant in formulations to enhance the spread and absorption of active ingredients.
Sarcosyl is extensively utilized in the formulation of facial cleansers, body washes, and baby products because it provides a gentle yet effective cleansing action.
Its ability to produce a rich, creamy foam without causing excessive dryness or irritation to the skin makes it particularly suitable for individuals with sensitive or delicate skin types.
In shampoos, especially sulfate-free varieties, Sarcosyl is a key ingredient because it enhances the product’s foaming ability, even in the presence of oils, while ensuring the hair remains soft and manageable.
Sarcosyl also appears in toothpaste and mouthwash formulations due to its dual role as a cleansing agent and an emulsifier, helping to stabilize flavors and active ingredients like fluoride.
In shaving creams and gels, Sarcosyl contributes to the generation of stable, luxurious foam, which provides an optimal environment for a smooth, irritation-free shaving experience.
Safety Profile:
Sarcosyl is considered safe for use in cosmetics and personal care products when used within recommended concentrations.
It is generally non-irritating and hypoallergenic but should not be ingested or used in excessive concentrations.
Sarcosyl is good for skin and hair.
It does not have any common side effects like skin irritation and sensitivity.
Sarcosyl is also vegan and can be added in concentrations of up to 5% in leave-on products and 15% in rinse-off products.
Further, this ingredient is non-comedogenic, so it does not clog pores or cause acne.
Sarcosyl can be used on all skin types.
