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SCUTELLARIA BAICALENSIS GEORGI EXTRACT

Scutellaria Baicalensis Georgi Extract is widely used in traditional medicine and cosmetics for its anti-inflammatory and antioxidant properties.
Scutellaria Baicalensis Georgi Extract is traditionally used in herbal medicine for its anti-inflammatory, anti-allergic, and antimicrobial properties.
Scutellaria Baicalensis Georgi Extract is commonly used in cosmetic products for soothing and conditioning the skin.

CAS Number: 94279-99-9
EC Number: 304-846-0
INCI Name: Scutellaria Baicalensis Root Extract
Molecular Formula: Not specific as this is a plant extract, but key compounds include baicalin, baicalein, wogonin, and oroxylin A.

SYNONYMS:
Baikal skullcap, Scutellaria baicalensis, Huang Qin, Chinese Skullcap, Scutellaria baicalensis root extract, Scutellaria extract, Radix Scutellariae, Scutellariae Baicalensis Extract, Skullcap root extract,

Scutellaria Baicalensis Georgi Extract is derived from the root of the Scutellaria baicalensis plant, also known as Baikal skullcap.
Scutellaria baicalensis, with the common name Baikal skullcap or Chinese skullcap, is a species of flowering plant in the family Lamiaceae.

Scutellaria Baicalensis Georgi Extract is an Extract that made from scutellaria baicalensis plant. With advanced Production techniques, we exact Baicalein Powder out of scutellaria baicalensis Plant and supply this Baicalein Powder in bulk quantity.
Scutellaria Baicalensis Georgi Extract mainly exists in scutellaria baicalensis.

Scutellaria Baicalensis Georgi Extract can reduce cerebral vascular resistance, improve cerebral blood circulation, increase cerebral blood flow, and the function of platelet aggregation.
So Scutellaria Baicalensis Georgi Extract can be used in treatment of cerebrovascular disease after paralysis.

Scutellaria Baicalensis Georgi Extract is a natural flavone (a type of flavonoid) isolated from scutellaria baicalensis.
Scutellaria Baicalensis Georgi Extract is also known as a dietary flavonoid and phytonutrient along with quercetin, apigenin, luteolin,and myricetin as it is found in high concentrations in various foods such as vegetables, fruits,beverages, and many traditional herbs.

Scutellaria Baicalensis Georgi Extract has been found to have multiple beneficial properties including antioxidant, anti-inflammatory, anti-allergic, and anti-cancer activities.
In particular, the anti-allergic effects of Scutellaria Baicalensis Georgi Extract have been verified in asthma, atopic dermatitis,and both Ig E-mediated and systemic allergic responses

Scutellaria Baicalensis Georgi Extract is obtained through various extraction methods such as ethanol extraction, supercritical fluid extraction, and ultrasonic-assisted extraction.

Scutellaria Baicalensis Georgi Extract is one of the main active compounds found in Scutellaria extract powder, comprising approximately 90% of the total flavonoids present in the plant.
The chemical formula of Scutellaria Baicalensis Georgi Extract is C21H18O11, and its molecular structure is characterized by a flavone backbone with two sugar moieties attached.

Scutellaria Baicalensis Georgi Extract has significant biological activity, has antibacterial, diuretic, anti-inflammatory, cholesterol-lowering, anti-thrombosis, relieves asthma, purging fire and detoxification, hemostasis, anti-abortion, anti-allergic and anti-spasmodic effects, and is also the role of mammalian liver sialidase Specific inhibitors, have the effect of regulating certain diseases.

USES and APPLICATIONS of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Scutellaria Baicalensis Georgi Extract is applied in the field of Pharmaceuticals.
Scutellaria Baicalensis Georgi Extract is applied in the field of Healthcare products.
Scutellaria Baicalensis Georgi Extract is applied in the field of Cosmetic products

Scutellaria Baicalensis Georgi Extract is commonly used in cosmetic products for soothing and conditioning the skin.
Scutellaria Baicalensis Georgi Extract is a natural plant-based supplement derived from the roots of Scutellaria baicalensis, a traditional Chinese herb.

-Health Care Products uses of Scutellaria Baicalensis Georgi Extract:
Scutellaria Baicalensis Georgi Extract is widely used in health care products, including dietary supplements and traditional Chinese medicines.
It is known for Scutellaria Baicalensis Georgi Extract's pharmacological actions such as antioxidant, anti-inflammatory, and neuroprotective properties that support overall health and wellness.

Scutellaria Baicalensis Georgi Extract is often added to health supplements, capsules, and tablets, promoting various health benefits such as improving liver function, preventing cancer, and reducing the risk of chronic diseases.

-Chinese Veterinary Medicine uses of Scutellaria Baicalensis Georgi Extract:
Scutellaria Baicalensis Georgi Extract has been used in Chinese veterinary medicine for centuries.
Scutellaria Baicalensis Georgi Extract is believed to have a cooling effect and is often used to treat animal diseases caused by heat or inflammation.

Scutellaria Baicalensis Georgi Extract is also used in Chinese veterinary medicine for treating various illnesses, including respiratory infections, gastric ulcers, and inflammatory conditions.

-Feed Additives uses of Scutellaria Baicalensis Georgi Extract:
Scutellaria Baicalensis Georgi Extract is also used as a feed additive for livestock and poultry.
Scutellaria Baicalensis Georgi Extract is known to have antioxidant and antimicrobial properties, which may help to improve animal health and growth.

Scutellaria Baicalensis Georgi Extract is used as a feed additive for increasing the production of eggs and meat, improving immune function, and preventing infectious diseases in animals.

-Uses of Scutellaria Baicalensis Georgi Extract:
*Anti-inflammatory:
Scutellaria Baicalensis Georgi Extract reduces skin inflammation, often used in soothing skincare formulations.

*Antioxidant:
Scutellaria Baicalensis Georgi Extract helps combat oxidative stress, making it popular in anti-aging products.

*Antibacterial:
Scutellaria Baicalensis Georgi Extract is effective in treating acne and other bacterial infections.

*Brightening:
Scutellaria Baicalensis Georgi Extract helps in reducing hyperpigmentation and promoting an even skin tone.

*Traditional Medicine:
Scutellaria Baicalensis Georgi Extract is used in Chinese medicine to treat conditions like respiratory infections, fevers, and gastrointestinal disorders.

COSMETIC AND SKINCARE APPLICATIONS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
*Anti-Aging:
Due to its high flavonoid content, Scutellaria Baicalensis Georgi Extract is effective in protecting the skin from photoaging and environmental damage caused by free radicals.

*Skin Brightening:
Its ability to inhibit melanin production makes Scutellaria Baicalensis Georgi Extract useful for treating hyperpigmentation and promoting an even skin tone.

*Anti-Acne:
Thanks to its antibacterial and anti-inflammatory properties, Scutellaria Baicalensis Georgi Extract’s included in formulations targeting acne-prone skin.

*Soothing and Calming:
Scutellaria Baicalensis Georgi Extract’s anti-inflammatory action makes it ideal for products meant to calm irritated skin, reduce redness, and improve conditions like eczema and psoriasis.

*Traditional and Herbal Medicine:
Traditional Chinese Medicine (TCM):
Known as "Huang Qin," this herb has been used for thousands of years in TCM.

Scutellaria Baicalensis Georgi Extract is often prescribed for treating fevers, respiratory infections, and as part of detoxifying formulas.
Scutellaria Baicalensis Georgi Extract is also believed to help cleanse the liver and calm the mind.

*Ayurveda:
While not as prominent in Ayurvedic practices, Scutellaria Baicalensis Georgi Extract is sometimes used in formulations to balance bodily energies and reduce inflammation.

FUNCTIONS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
1. Antioxidant Effects
Scutellaria Baicalensis Georgi Extract is a potent antioxidant that helps to protect the body against oxidative stress caused by free radicals.
These unstable molecules can damage cells and tissues and contribute to the development of various chronic diseases such as cancer, diabetes, and heart disease.

Scutellaria Baicalensis Georgi Extract works by neutralizing free radicals and other harmful compounds, which in turn can help to slow down the aging process, improve cardiovascular health, and reduce the risk of various diseases.

2. Neuroprotective Effects
Scutellaria Baicalensis Georgi Extract has been widely studied for its neuroprotective effects, which may help to prevent and manage various neurological disorders such as Alzheimer's disease, Parkinson's disease, and stroke.

Scutellaria Baicalensis Georgi Extract works by inhibiting neuronal death and promoting neuronal survival, as well as by improving blood flow to the brain.
Scutellaria Baicalensis Georgi Extract also has potential as a treatment for depression and anxiety, due to its ability to modulate neurotransmitter function.

3. Cardiovascular Health
Scutellaria Baicalensis Georgi Extract has been shown to have a beneficial effect on cardiovascular health, due to its antioxidant and anti-inflammatory properties.

Scutellaria Baicalensis Georgi Extract may help to reduce blood pressure, improve cholesterol levels, and prevent the development of atherosclerosis (hardening of the arteries).
Scutellaria Baicalensis Georgi Extract may be useful in the prevention and management of various cardiovascular diseases such as heart disease and stroke.

MAIN ACTIVE COMPONENTS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
*Flavonoids, especially baicalin and baicalein
*Triterpenoids
*Phenolic acids

KEY ACTIVE COMPONENTS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
*Baicalin:
A flavonoid glycoside with potent anti-inflammatory, antiviral, and antioxidant properties.

*Baicalein:
Another flavonoid with similar anti-inflammatory effects, also known for its anticancer potential.

*Wogonin:
A flavone that has been studied for its anti-anxiety, anti-cancer, and neuroprotective properties.

*Oroxylin A:
A flavonoid with antioxidant and neuroprotective activities.

HEALTH BENEFITS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
*Anti-inflammatory and Anti-Allergic:
Scutellaria Baicalensis Georgi Extract is renowned for reducing inflammation and modulating the immune system.
Scutellaria Baicalensis Georgi Extract is used to treat allergies, asthma, and conditions involving inflammation, such as arthritis.

*Antioxidant Effects:
Scutellaria Baicalensis Georgi Extract neutralizes free radicals, reducing oxidative damage in the skin and body.
This is beneficial in anti-aging skincare and supplements aimed at promoting overall health and longevity.

*Antibacterial and Antiviral:
Scutellaria Baicalensis Georgi Extract has shown efficacy against a wide range of bacterial infections, including those responsible for acne and respiratory infections.
Scutellaria Baicalensis Georgi Extract is also being researched for antiviral properties, particularly against influenza and hepatitis viruses.

*Neuroprotective:
Some studies suggest that compounds in Scutellaria baicalensis help protect neurons from damage, making Scutellaria Baicalensis Georgi Extract a potential agent for treating neurodegenerative diseases like Alzheimer's and Parkinson’s.

*Cancer Research:
The active components in Scutellaria Baicalensis Georgi Extract, particularly baicalin and wogonin, are being investigated for their ability to inhibit cancer cell proliferation and induce apoptosis (programmed cell death) in cancer cells.

BIOLOGICAL ACTIVITY OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Scutellaria Baicalensis Georgi Extract also one of the effective ingredients of traditional Chinese medicine Scutellaria baicalensis Georgi.
Pharmacological studies have shown that Scutellaria Baicalensis Georgi Extract has more and stronger biological activities than baicalin, and has less toxic and side effects.

Drug metabolism studies have also shown that baicalin is difficult to be directly absorbed in the digestive tract, and baicalin is absorbed faster, and its bioavailability is stronger than baicalin.

a) Antioxidant and free radical scavenging effect
Scutellaria Baicalensis Georgi Extract can scavenge free radicals and prevent fibroblast damage caused by oxygen free radicals such as hydroperoxidase and superoxide anion.

b) Anti-allergic
Scutellaria Baicalensis Georgi Extract can inhibit the release of SRS-A and LT, while reducing the release of LTC and D1, and relax the guinea pig's bronchial smooth muscles in a contracted state.

It can relieve allergic asthma in guinea pigs, and can relieve asthma in the whole animal, and has a synergistic effect with ephedrine to antagonize allergic edema and inflammation.
In addition, Scutellaria Baicalensis Georgi Extract also has a certain inhibitory effect on passive systemic allergies and skin allergies in animals.

c) Anti-tumor effect
Scutellaria Baicalensis Georgi Extract showed a dose-effect relationship to inhibit the mutagenic effects of aflatoxin BI and nitrosomonas on Salmonella.
In addition, Scutellaria Baicalensis Georgi Extract enhanced the inhibitory effects of interleukin and tumor necrosis factor.

The inhibitory effect of Scutellaria Baicalensis Georgi Extract on the proliferation of human breast cancer cell line MDA2MB2435 is far greater than that of pepitin, but the cytotoxicity is very small.

FUNCTIONS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
1.Scutellaria Baicalensis Georgi Extract can promote secretion of bile, and promote movements of extra body intestines;
2.Scutellaria Baicalensis Georgi Extracthas anti-histamine effect, and can inhibit edema caused by carrageenin.
3.Scutellaria Baicalensis Georgi Extracthas the function of inhibition of diabetic complications.
3.Scutellaria Baicalensis Georgi Extracthas anti-allergenic,anti-tumor and anti-toxin effect.
4.Scutellaria Baicalensis Georgi Extractcan enhance spectrum antibiotic
5.Scutellaria Baicalensis Georgi Extractcan prevents atherosclerosis.
6.Scutellaria Baicalensis Georgi Extracthave anti-hepatitis B virus effect.
8.Scutellaria Baicalensis Georgi Extracthas been used to anti-bacterial ingredients of Scutellaria.
Scutellaria Baicalensis Georgi Extract has the functions of treatment of trachoma, and the curative effect is similar to that of rifampin by the eye drops containing 3% products.
9.Scutellaria Baicalensis Georgi Extractcan inhibit the melanin formation, therefore both used in medicine, also can be used in cosmetics, is a good functional cosmetics raw material.

PHARMACOLOGICAL RESEARCH OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Liver Health:
Studies suggest that Scutellaria Baicalensis Georgi Extract can help protect the liver from damage caused by toxins and stress, making it a candidate for treatments related to liver disorders.

Cardiovascular Benefits:
Scutellaria Baicalensis Georgi Extract has shown promise in reducing hypertension, protecting the heart, and improving blood circulation.

EXTRACTION PROCESS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Water/Alcohol Extraction:
The roots of the plant are typically dried and then extracted using water or alcohol to isolate the active flavonoids.
Powder Form:
After extraction, the liquid is often dried into a powder form, which is used in supplements, cosmetics, and traditional medicine.

SUSTAINABILITY AND SOURCING OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Scutellaria Baicalensis Georgi Extract is widely cultivated in East Asia, particularly in China.
As interest in the plant grows globally for its health and cosmetic applications, sustainable sourcing and cultivation are essential to avoid overharvesting wild populations.
This should give you a comprehensive understanding of Scutellaria Baicalensis Georgi Extract and its uses across various industries. Let me know if you need further details!

DISTRIBUTION OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
The plant is native to China, Korea, Mongolia, and Russia in the Russian Far East and Siberia.

TRADITIONAL CHINESE MEDICINE OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Traditional Chinese medicine
It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it has the name huángqín (Chinese: 黄芩).
As a Chinese traditional medicine, huang qin usually refers to the dried root of S. baicalensis Georgi, S. viscidula Bge., S. amoena C.H. Wright, and S. ikoninkovii Ju.

PHYTOCHEMICALS OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
Main article: Scutellaria § Constituents and pharmacology
Several phytochemicals have been isolated from the root; baicalein, baicalin, wogonin, norwogonin, oroxylin A and β-sitosterol are the major ones.

NAMES OF SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
As the term 'skullcap' is applied to over 200 plant varieties, the scientific name is used.
Sometimes, Scutellaria lateriflora (North American skullcap) is mistaken for S. baicalensis.

PHYSICAL and CHEMICAL PROPERTIES of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
INCI Name: Scutellaria Baicalensis Root Extract
CAS Number: 94279-99-9
EC Number: 304-846-0
Molecular Formula: Not specific as this is a plant extract, but key compounds include baicalin, baicalein, wogonin, and oroxylin A.
Appearance: Yellow to brown powder or liquid extract (depending on the extraction method)
Solubility: Soluble in water, alcohol, and other polar solvents
Odor: Characteristic, earthy scent
Melting Point: Not applicable as it is a plant extract

FIRST AID MEASURES of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of SCUTELLARIA BAICALENSIS GEORGI EXTRACT:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available