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Siloxane D5, also known as D5 and D5, is an organosilicon compound with the formula [(CH3)2SiO]5.
Siloxane D5 is a colorless and odorless liquid that is slightly volatile.
A cyclic volatile Siloxane D5 used in cosmetic and personal care products.
CAS: 541-02-6
MF: C10H30O5Si5
MW: 370.77
EINECS: 208-764-9
Synonyms
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane;CD3770;cyclicdimethylsiloxanepentamer;Cyclopentasiloxane, decamethyl-;D3770;Decamethylcylopentasiloxane;siliconsf1202;unioncarbide7158siliconefluid;DECAMETHYLCYCLOPENTASILOXANE;541-02-6;Cyclopentasiloxane, decamethyl-;Cyclomethicone 5;2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane;CYCLOPENTASILOXANE;Dimethylsiloxane pentamer;Dow corning 345;NUC silicone VS 7158;Silicon SF 1202;Ciclopentasiloxane;Cyclic dimethylsiloxane pentamer;Cyclomethicone D5;Dekamethylcyklopentasiloxan;D5-sil;KF 995;CCRIS 1328;VS 7158;HSDB 5683;UNII-0THT5PCI0R;0THT5PCI0R;Ddecamethylcyclopentasiloxane;EINECS 208-764-9;SF 1202;BRN 1800166;DTXSID1027184;JEESILC CPS-211;XIAMETER PMX-0245;DTXCID907184;CYCLOPENTASILOXANE (D5);D5;EC 208-764-9;4-04-00-04128 (Beilstein Handbook Reference);KF-995;DOW CORNING ST CYCLOMETHICONE 5;OCTAMETHYLCYCLOTETRASILOXANE (D5);KP-545 COMPONENT CYCLOMETHICONE 5;2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane;CYCLOMETHICONE 5 (USP-RS);CYCLOMETHICONE 5 [USP-RS];MFCD00046966;Dekamethylcyklopentasiloxan [Czech];decamethyl cyclopentasiloxane;C10H30O5Si5;Lightening Serum;D5 Cyclomethicone;dimethylcyclopentasiloxane;Decamethylcylopentasiloxane;UNII: 0THT5PCI0R;SCHEMBL28497;N-Propylheptamethyltrisiloxane;CHEMBL1885178;3CE PINK IM GOOD MASCARA;CHEBI:191092;Decamethylcyclopentasiloxane, 97%;Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-;CYCLOMETHICONE 5 [WHO-DD];BCP15826;Tox21_303170;CD3770;CYCLOPENTASILOXANE, DECAMETHYL;AKOS008901199;CS-W009767;DB11244;HY-W009051;DECAMETHYLCYCLOPENTASILOXANE [MI];NCGC00163981-01;NCGC00257224-01;AS-59731;CAS-541-02-6;DA-72620;DECAMETHYLCYCLOPENTASILOXANE [HSDB];D1890;D3770;Decamethylcyclopentasiloxane (cyclic monomer);NS00043162;D78203;S05475;Decamethylcyclopentasiloxane, analytical standard;Q414350;decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane;Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard;2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #;D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material
Used in dermal exposure and inhalation toxicity study.
Siloxane D5 is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Siloxane D5 is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
D4, D5 and D6 are ingredients from the group of silicones, specifically siloxanes, with skin and hair conditioning properties, acting as solvents and emollients.
Siloxane D5 are also added to cosmetics to ensure appropriate sensory and application properties: they give smoothness, slip and silky effect, improve their consistency and stability.
Siloxane D5 Chemical Properties
Melting point: -44°C
Boiling point: 90 °C/10 mmHg (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
Vapor pressure: 33.2Pa at 25℃
Refractive index: n20/D 1.396(lit.)
Fp: 162 °F
Storage temp.: 2-8°C
Solubility: <0.0001g/l (calculated)
Form: Liquid
Specific Gravity: 0.959
Color: Colorless
Explosive limit: 0.52-7%(V)
Water Solubility: Immiscible with water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,2848
BRN: 1800166
Dielectric constant: 2.5（20℃）
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: XMSXQFUHVRWGNA-UHFFFAOYSA-N
LogP: 8.07 at 24.6℃
CAS DataBase Reference: 541-02-6(CAS DataBase Reference)
NIST Chemistry Reference: Siloxane D5 (541-02-6)
EPA Substance Registry System: Siloxane D5 (541-02-6)
Uses
Intermediate in the manufacture of high mol wt Siloxane D5.
Carrier ingredient in personal care products; dry cleaning solvent.
Siloxane D5 and decamethylcyclopentasiloxane are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
Siloxane D5 are basic members of the broad family of silicone materials and are used as building blocks for the production of a diverse array of silicone polymers.
A common denominator for Siloxane D5 is that they contain repeating units of silicone (Si) and oxygen (O) atoms in a closed loop, giving it a “cyclic” structure.
