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Sodium acetylated hyaluronate has the advantages of high skin affinity, efficient and lasting moisturizing, softening stratum corneum, strong skin softening, enhancing skin elasticity, improving skin roughness,etc.
Sodium acetylated hyaluronate is refreshing and non-greasy, and can be widely used in cosmetics such as lotion, mask and essence
Sodium acetylated hyaluronate is a hydrating, humectant skin care ingredient derived from the NMF (natural moisturizing factor) hyaluronic acid.
CAS Number: 287390-12-9
Synonyms: Sodium Acetyl Hyaluronate, 287390-12-9, 690-986-4, sodium acetylated hyalutonate
Sodium acetylated hyaluronate, is a specialty HA derivative which is synthesized from the Natural Moisturizing Factor Sodium Hyaluronate (HA) by acetylation reaction.
The hydroxyl group of HA is partially replaced with acetyl group.
Sodium acetylated hyaluronate owns both lipophilic and hydrophilic properties.
Sodium acetylated hyaluronate is the acetyl ester of sodium hyaluronate, where some of hyaluronic acid’s hydroxyl groups are replaced with acetyl groups.
This swap in groups allows for enhanced bioavailability and better stability, increasing benefits since this allows for penetration deeper into skin and lets the ingredient reach its destination sooner.
While hydrating and plumping skin, sodium acetylated hyaluronate also assists in mitigating environmental damage and visibly reducing the appearance of fine lines and wrinkles, making it an interesting ingredient to explore further for its anti-aging properties.
Sodium Acetylated Hyaluronate is a variation of current IT moisturizer, Hyaluronic acid, where some water-loving -OH groups are replaced by amphipathic (partly water-loving and partly water-hating) acetyl groups.
The modified molecule is claimed to have even better moisture retention ability than normal HA and better affinity to the skin surface.
The better affinity comes from the acetyl groups that act as tiny "anchors" to attach the HA molecule to the skin.
Staying on top of the skin better and longer means longer-lasting surface hydration and improved elasticity.
Sodium acetylated hyaluronate is also less sticky and more cosmetically elegant than normal HA, so no wonder the nickname of this molecule is super hyaluronic acid.
Sodium acetylated hyaluronate is a distinctive HA-derivative which is easy to use due to amphipathic properties, has high suppleness of the stratum corneum, and offers high water-retentiivity (more than 2 times than normal HA).
Sodium acetylated hyaluronate has a strong affinity for skin, and remains firmly on the surface of skin to prevent water from evaporating from skin.
Sodium acetylated hyaluronate is a refreshing and non-greasy moisturizing agent.
It is a derivative of sodium hyaluronate which is prepared by acetylation of sodium hyaluronate.
Sodium acetylated hyaluronate owns both lipophilic and hydrophilic properties.
It helps to promote high affinity and adsorption properties for the skin.
It provides high skin affinity, efficient & lasting moisturizing, stratum corneum softening, enhanced skin elasticity and improved skin roughness.
Sodium Acetylated Hyaluronate is used in cleansing cosmetics and skin care products such as facial cleanser, cleansing cream, cleansing soap, body wash, essence, make-up water, lotion, toner, cream and UV protection.
Acetylation is a chemical process and describes the exchange of a hydrogen atom by an acetyl group.
The exchange can take place either at the functional groups (-OH, -SH, -NH2) or directly at a -C-H bond.
An acetyl group in turn denotes the chemical structure -C(O)CH3.
Sodium acetylated hyaluronate is composed of the carbonyl and methyl groups and forms the acyl radical of acetic acid. Hence the name: acetyl is derived from the Latin term “acetum” (vinegar).
For example, drugs obtained by acetylation have been known for a very long time: Acetylsalicylic acid (aspirin) obtained in chemically pure form is certainly the preparation most commonly used in this context.
Another example: the acetylation of morphine produces heroin (diacetylmorphine).
And oxaceprol, a very well-known active ingredient used, among other things, in drugs to treat degenerative joint diseases such as arthritis, is also obtained by acetylation.
Sodium Acetylated Hyaluronate is a highly active ingredient of the latest generation, which is used in exclusive premium anti-aging products.
With good reason: sodium acetylated hyaluronate is in fact able to penetrate the skin significantly deeper than other classic hyaluronic acids.
Sodium acetylated hyaluronate has both lipophilic and hydrophilic properties.
The acetyl group, which is strongly lipophilic, helps acetylated hyaluronic acid adhere firmly, which significantly reduces an evaporative effect.
The skin is supplied with moisture throughout the day.
With the active ingredient sodium acetylated hyaluronate, the first signs of skin aging can therefore be counteracted within a very short time.
Thanks to the increased stability against hyaluronidases (degradation enzymes), a long-lasting effect is also guaranteed.
Sodium acetylated hyaluronate therefore makes the skin significantly more elastic and supple, not least because it repairs damaged and/or rough skin by significantly improving the moisture content in the uppermost layer of the epidermis (stratum corneum).
Studies have already shown that after regular application over four weeks (concentration: 0.1 percent sodium acetylated hyaluronate), the skin elasticity of volunteers was quite significantly increased by 1.6 times.
The skin also appeared noticeably softer and smoother.
Furthermore, the study showed that even two hours after application, the skin had a moisture content of 103.4 percent.
By comparison, this value was 65.3 percent at the same time in test subjects who had used classic hyaluronic acid, and only 29.6 percent in a placebo group.
Sodium acetylated hyaluronate keeps the skin well moisturized for a total of twelve hours.
Sodium acetylated hyaluronate is the acetyl ester of sodium hyaluronate, where some of hyaluronic acid’s hydroxyl groups are replaced with acetyl groups.
This swap in groups allows for enhanced bioavailability and better stability, increasing benefits since this allows for penetration deeper into skin and lets the ingredient reach its destination sooner.
While hydrating and plumping skin, Sodium acetylated hyaluronate also assists in mitigating environmental damage and visibly reducing the appearance of fine lines and wrinkles, making it an interesting ingredient to explore further for its anti-aging properties.
Sodium acetylated hyaluronate is a derivative that is formed by the introduction of an acetyl group into the molecule of sodium hyaluronate.
The repeating units constituting this hyaluronic acid itself are glucuronic acid and N-acetyl glucosamine.
In hyaluronic acid, an acetyl group will be introduced through a chemical modification in its chain to enhance its lipophilicity so that it could easily get absorbed and utilized by skin.
Sodium acetylated hyaluronate is a derivative of hyaluronic acid, a naturally occurring substance in the body known for its exceptional ability to retain moisture.
This modified form of hyaluronic acid has been acetylated, meaning it has undergone a chemical process where acetyl groups are added to the molecule.
This modification enhances certain properties of the original hyaluronic acid, making it particularly beneficial for use in skincare and cosmetic products.
One of the key advantages of Sodium Acetylated Hyaluronate is its enhanced moisturizing ability.
While regular hyaluronic acid is already well-known for its capacity to attract and hold large amounts of water, the acetylation process makes this derivative even more effective at maintaining skin hydration.
Sodium acetylated hyaluronate has a unique ability to form a protective, moisturizing film on the surface of the skin, which helps to prevent water loss and keeps the skin feeling soft, smooth, and supple for longer periods.
Additionally, Sodium Acetylated Hyaluronate is known for its ability to penetrate the upper layers of the skin more effectively than regular hyaluronic acid.
This allows it to deliver moisture deeper into the skin, improving overall hydration and plumpness.
Its superior water-binding capacity helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful and radiant complexion.
Moreover, this ingredient is often praised for its soothing and calming properties.
Sodium acetylated hyaluronate can help to reduce inflammation and irritation, making it suitable for individuals with sensitive or reactive skin.
Its ability to enhance the skin's barrier function also contributes to its protective qualities, helping to shield the skin from environmental stressors and pollutants.
In summary, Sodium Acetylated Hyaluronate is a highly effective moisturizing and skin-conditioning agent that offers several benefits over traditional hyaluronic acid.
Its ability to deeply hydrate, improve skin elasticity, and provide soothing and protective effects makes it a valuable ingredient in many skincare formulations designed to enhance skin health and appearance.
Uses:
Sodium Acetylated Hyaluronate is widely used in various skincare and cosmetic products due to its enhanced moisturizing, hydrating, and skin-soothing properties.
One of its primary uses is in moisturizers and creams, where it helps to deeply hydrate the skin by forming a moisture-retaining film on its surface.
This not only prevents water loss but also provides long-lasting hydration, leaving the skin feeling soft, supple, and smooth.
The ingredient is particularly effective in maintaining skin moisture levels, making it ideal for products designed to combat dryness and improve skin texture.
In anti-aging formulations, Sodium Acetylated Hyaluronate plays a crucial role in reducing the appearance of fine lines and wrinkles.
Its superior ability to bind and retain water enhances skin elasticity and plumpness, giving the skin a more youthful and radiant look.
By delivering moisture deep into the skin, it helps to restore the skin’s natural bounce and firmness, making it a valuable component in serums, creams, and lotions targeting signs of aging.
The ingredient is also commonly found in serums and essences due to its lightweight yet highly effective hydrating properties.
These products benefit from Sodium Acetylated Hyaluronate's ability to penetrate the skin's upper layers, delivering intense hydration without leaving a heavy or greasy residue.
This makes it suitable for all skin types, including oily and combination skin, as it provides moisture without clogging pores.
In soothing and calming products, such as those designed for sensitive or irritated skin, Sodium Acetylated Hyaluronate helps to reduce redness and inflammation.
Its anti-inflammatory properties make it beneficial in products aimed at calming the skin and restoring its natural barrier function.
This is why it is often included in formulations for people with sensitive skin conditions, such as rosacea or eczema, as it helps to provide comfort and protection.
Additionally, Sodium Acetylated Hyaluronate is used in sunscreens and after-sun care products for its ability to maintain hydration and support the skin's natural barrier against environmental stressors, including UV radiation.
Its moisturizing and soothing effects help to counteract the drying effects of sun exposure and provide relief to sun-exposed skin.
In summary, Sodium Acetylated Hyaluronate is utilized in a wide range of skincare products due to its superior moisturizing, anti-aging, soothing, and protective properties.
Its ability to deeply hydrate, enhance skin elasticity, and calm irritation makes it a highly sought-after ingredient in formulations designed to improve overall skin health and appearance.
Sodium acetylated hyaluronate is also extensively used in hydrating facial masks, both in sheet masks and leave-on formulations.
In these products, its ability to deliver and retain moisture helps to provide an instant boost of hydration to the skin.
The ingredient enhances the efficacy of masks by ensuring prolonged hydration, leaving the skin feeling refreshed, plump, and revitalized.
This makes it particularly beneficial for use in intensive hydration treatments designed to combat dryness and dehydration caused by environmental factors or lifestyle habits.
In eye creams and gels, Sodium Acetylated Hyaluronate is favored for its gentle yet effective moisturizing properties.
The delicate skin around the eyes is particularly prone to dryness and fine lines, and this ingredient helps to provide targeted hydration, reducing the appearance of puffiness, dark circles, and crow’s feet.
Its ability to lock in moisture without irritating the sensitive eye area makes it a key component in products aimed at maintaining a youthful and refreshed appearance around the eyes.
Sodium Acetylated Hyaluronate is also commonly found in lip care products, such as balms, glosses, and treatments.
Its superior hydrating properties help to keep the lips soft, smooth, and well-moisturized, preventing dryness, chapping, and flaking.
By forming a protective barrier on the lips, it helps to retain moisture and shield against harsh environmental conditions, such as cold weather or wind.
In primers and foundations, Sodium Acetylated Hyaluronate is used to provide a smooth, hydrated base that enhances makeup application and longevity.
Its moisturizing effect helps to create a more even skin surface, reducing the appearance of dry patches and fine lines.
This results in a more flawless and radiant makeup finish, as well as improved wear throughout the day.
Furthermore, Sodium Acetylated Hyaluronate is utilized in hair care products, particularly in conditioners, hair masks, and leave-in treatments.
In these formulations, it helps to retain moisture in the hair shafts, improving hair elasticity, reducing frizz, and enhancing softness and shine.
Its moisturizing properties make it ideal for products designed to repair and nourish dry, damaged, or chemically treated hair.
Sodium Acetylated Hyaluronate is incorporated into dermatological treatments and medical-grade skincare products, especially those aimed at post-procedure care.
Its ability to soothe and hydrate the skin makes it valuable for calming irritation and supporting the healing process after treatments like chemical peels, laser therapy, or microneedling.
In conclusion, Sodium Acetylated Hyaluronate is a versatile and highly effective ingredient used across a wide array of skincare and cosmetic products.
Its ability to deeply hydrate, soothe, and protect the skin, as well as enhance the performance of other ingredients, makes it a crucial component in formulations aimed at improving skin and hair health and appearance.
Safety Profile:
While Sodium Acetylated Hyaluronate is typically gentle and suitable for most skin types, some individuals may experience allergic reactions or sensitivity.
Symptoms can include redness, itching, swelling, or irritation.
For those with sensitive skin or a history of allergic reactions, it’s advisable to conduct a patch test before using products containing this ingredient.
Although Sodium Acetylated Hyaluronate is not typically comedogenic (does not clog pores), individuals with very oily or acne-prone skin should monitor their skin’s reaction, as different formulations might vary in their effects on skin.
In rare cases, products containing Sodium Acetylated Hyaluronate might cause reactions when combined with certain active ingredients like strong acids or retinoids, which could increase the potential for irritation or sensitivity.
It’s important to follow product guidelines and layering instructions.
