Sodium adipate is a chemical organic compound with formula Na2C6H8O4.
Sodium adipate is the sodium salt of adipic acid.
As a food additive, it has the E number E356 as is used as a buffering agent and as an acidity regulator.
CAS Number: 7486-38-6
EC Number: 231-293-5
IUPAC Name: Disodium hexanedioate
Chemical Formula: C6H8Na2O4
Other names: 7486-38-6, Hexanedioic acid, disodium salt, disodium hexanedioate, Hexanedioic acid, sodium salt, Adipic acid, sodium salt, ADIPIC ACID, DISODIUM SALT, 1,4-Butanedicarboxylic acid disodium salt, 3XG6T5KYKM, di-sodium adipate, EINECS 231-293-5, EINECS 245-577-1, Hexanedioic acid, sodium salt (1:?), Hexanedioic acid, sodium salt (1:2), INS NO.356, DTXSID1044726, INS-356, EC 231-293-5, E-356, DTXCID9024726, DTXSID201011014, 231-293-5, 245-577-1, Adipic Acid Disodium Salt, disodium;hexanedioate, UNII-3XG6T5KYKM, MFCD00070498, SCHEMBL107905, AKOS025295713, AS-75598, E356, A0592, CS-0455468, NS00078434, D88288, Q423296
Sodium adipate has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of hydrophilic drugs.
The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media.
Adipic acid is used to make bisobrin an antifibrinolytic.
Sodium adipate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Adipic acid is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Acidity Regulator / Buffering Agent - Changes or maintains the acidity or basicity of food/cosmetics.
Flavor / Flavoring / Flavor Enhancer - Provides or enhances a particular taste or smell.
Adipic acid occurs naturally in living cells, but is commercially prepared from the oxidation of cyclohexanol by concentrated nitric acid.
Small but significant amounts of adipic acid are used as a food ingredient (E355) as a flavorant and gelling aid.
Adipic acid is used in some calcium carbonate antacids to make them tart.
As an acidulant in baking powders, Hexanedioic acid, disodium salt avoids the undesirable hygroscopic properties of tartaric acid.
Hexanedioic acid, disodium salt, rare in nature, does occur naturally in beets, but this is not an economical source for commerce compared to industrial synthesis.
Adipic acid is approved to use as food additive in EU and generally recognized as safe food substance in US.
Hexanedioic acid, disodium salt is the sodium salt of adipic acid.
The function(s) performed by the food additive when used in cooking.
White odourless crystals or crystalline powder
Sodium adipate is a sodium salt of and adipic (hexanedioic) acid - a C6 dicarboxylic acid.
Hexanedioic acid, disodium salt is a colorless crystalline solid which is readily soluble in water and is effective as an acidity regulator and complexing agent.
The acidity regulatory property of sodium adipate finds many uses in pharmaceutical drug development.
In addition, sodium adipate is used as a stabilizer of PVC.
Sodium salt of adipic acid.
Adipic Acid is a synthetic food acid from nitric acid or from beetroot.
As Hexanedioic acid, disodium salt is synthetic using highly toxic petroleum hexanes, adipic acid would not be sensible to use this product on any long term basis.
Sodium Adipic is used as an acidity regulator.
Only a small amount can be metabolised by humans and is listed as having teratogenic properties, which is an abnormal congenital deformity in embryos.
Adipate is the salt product of a reaction between adipic acid and a basic, or high pH, compound.
A salt, in the chemical sense rather than the table salt meaning, is an ionic compound with no net charge that is formed when an acid reacts with a base.
An ionic compound occurs when a positively charged ion bonds with a negatively charged ion.
There are several forms of adipate with different compositions and uses.
Examples include the plastic additives Bis(2-ethylhexyl) adipate (DEHA) and dioctyl adipate (DOA), and the food additives potassium adipate and sodium adipate.
Adipic acid, from which adipate arises, takes the form of a white powder that is typically manufactured rather than found in nature.
Chemically, adipic acid belongs to the class of dicarboxylic acids, organic compounds that have two carboxylic acid functional groups.
A compound is organic if it contains carbon.
The chemical formula of adipic acid is (CH2)4(CO2H)2.
As an Adipic acid, when it is added to water, Adipic acid releases hydrogen ions, or charged hydrogen atoms, into the solution, giving it a lower pH and a sour taste.
In Adipic acids capacity as a food additive, adipate serves as an acidity regulator, or a pH control agent.
An acidity regulator is added to alter the acidity or basicity of a food.
Each acidity regulator has an E number listing.
Potassium adipate, which is the potassium salt formed from an adipic acid reaction, has the E number “E357” and sodium adipate, which is the sodium salt arising from an adipic acid reaction with a base, has the E number “E356.”
These compounds lend a sour flavor to foods and may be used as a gelling agent.
Sodium adipate may be prepared by reaction of adipic acid with sodium carbonate.
Also, the neutralization of sodium hydroxide with an ethanolic solution of sodium adipate adipic supplies.
Property Name and Property Value
Molecular Weight: 190.10
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 3
Exact Mass: 190.02179730
Monoisotopic Mass: 190.02179730
Topological Polar Surface Area: 80.3 Ų
Heavy Atom Count: 12
Complexity: 103
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Use and Manufacturing
Use Classification
Food additives
Industry Uses
Lubricants and lubricant additives
Processing aids, not otherwise listed
General Manufacturing Information:
Industry Processing Sectors
Paper manufacturing
Petroleum lubricating oil and grease manufacturing
Sodium adipate is used in the following products: lubricants and greases, non-metal-surface treatment products, polymers, adhesives and sealants, coating products, fillers, putties, plasters, modelling clay and cosmetics and personal care products.
Hexanedioic acid, disodium salt is used in the following areas: formulation of mixtures and/or re-packaging.
Sodium adipate is used for the manufacture of: rubber products, plastic products and mineral products (e.g. plasters, cement).
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and of substances in closed systems with minimal release.
Hexanedioic acid, disodium salt is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, lubricants and greases, polymers and cosmetics and personal care products.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).
Disodium adipate is used in the following products: non-metal-surface treatment products, lubricants and greases, polymers, adhesives and sealants, coating products and fillers, putties, plasters, modelling clay.
Sodium adipate is used in the following areas: formulation of mixtures and/or re-packaging.
Sodium adipate is used for the manufacture of: rubber products, plastic products and mineral products (e.g. plasters, cement).
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Disodium adipate is used in the following products: adhesives and sealants, fillers, putties, plasters, modelling clay, lubricants and greases, coating products, finger paints, non-metal-surface treatment products, polymers and cosmetics and personal care products.
Release to the environment of this substance can occur from industrial use: formulation in materials and formulation of mixtures.
Sodium Adipic is found in Herbal salts.
Disodium adipate is metabolised in the body or excreted in the urine.
Adipic Acid is used as a firming and raising agent used in baking powder, beer, all fruit drinks, jams, pudding mixes, ice blocks, margarine, etc.
Also used in the production of plastics including PVC, and also in antacids, which is strange considering disodium adipate is an acid.
Sodium adipate is used as a food additive as a complexing agent and an acidity regulator.
In addition, it is used as a stabilizer of PVC.