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CAS Number: 61789-32-0
Synonyms: Sodium 2-hydroxyethyl sulfonate, Fatty acids, coco, 2-sulfoethyl esters, sodium salts, Igepon AC-78, Jordapon CI
Molecular Formula: C₂₈H₅₆Na₂O₁₀S₂
INCI Name: Sodium Cocoyl Isethionate
Appearance: White powder, flakes, granules, or noodles
Solubility: Soluble in water
Chemical Structure
Sodium Cocoyl Isethionate is the sodium salt of the fatty acid ester of isethionic acid.
It consists of coconut fatty acid chains esterified to isethionic acid, forming an anionic surfactant.
The structure contributes to its mildness and skin compatibility.
Applications in Personal Care
Sodium Cocoyl Isethionate is widely used in personal care products due to its gentle cleansing properties.
Shampoos
SCI is incorporated into shampoos for its ability to cleanse hair without stripping natural oils, making it suitable for dry or sensitive scalps.
Cleansing Bars
Solid cleansing bars, including syndet bars, utilize SCI for its foaming and cleansing properties.
It helps create a hard, long-lasting bar that doesn't crumble easily. SCI rinses off cleanly without leaving residue.
Facial Cleansers
SCI is used in facial cleansers for its mildness, making it suitable for daily use on sensitive facial skin.
Body Washes
In body washes, SCI provides effective cleansing while maintaining skin hydration.
Shaving Creams
SCI is included in shaving creams for its ability to create a creamy lather that softens hair and facilitates a smooth shave.
Baby Care Products
Due to its gentle nature, SCI is used in baby shampoos and body washes, minimizing the risk of irritation.
Safety and Toxicology
Skin Compatibility
Studies have shown that SCI is milder and less damaging to the skin barrier compared to other surfactants like sodium dodecyl sulfate (SDS).
It is less likely to cause irritation or dryness, making it suitable for sensitive skin.
Toxicity
Acute oral toxicity studies indicate an LD50 greater than 5000 mg/kg bodyweight, suggesting low toxicity.
Dermal application of 1.0-3.0% w/w aqueous solutions did not cause significant irritation.
Regulatory Status
Considered safe for use in cosmetic formulations at concentrations up to 50% in rinse-off products and 17% in leave-on products.
Environmental Impact
SCI is biodegradable and considered environmentally friendly, making it a preferred choice for sustainable and eco-friendly formulations.
However, the manufacturing process may involve ethoxylation, which can lead to the presence of impurities like 1,4-dioxane, a potential environmental contaminant.
Research and Development
Ongoing studies focus on enhancing the solubilization and effectiveness of SCI in various formulations.
Research aims to address its limited solubility in water by incorporating CI ions within micelles and emulsifying SCI.
Advancements in production methods aim to reduce environmental impact and improve the purity of SCI.
SAFETY INFORMATION ABOUT SODIUM COCOYL ISETHIONATE
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
