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SODIUM DIETHYLHEXYL SULFOSUCCINATE

SODIUM DIETHYLHEXYL SULFOSUCCINATE

Sodium Diethylhexyl Sulfosuccinate is an anionic surfactant widely used as a high-efficiency wetting agent, dispersant, and emulsifier in personal care, pharmaceutical, and industrial formulations.
Sodium Diethylhexyl Sulfosuccinate is commonly known as Docusate Sodium, and Sodium Diethylhexyl Sulfosuccinate is valued for very strong surface tension reduction that promotes rapid wetting and fast penetration into porous substrates.
Sodium Diethylhexyl Sulfosuccinate is typically supplied as a solution in water, alcohol, or solvent blends, and Sodium Diethylhexyl Sulfosuccinate use level must be optimized because Sodium Diethylhexyl Sulfosuccinate can increase irritation potential in high-concentration systems.

CAS Number: 577-11-7
EC Number: 209-406-4
Molecular Formula: C20H37NaO7S
Molecular Weight: 444.56 g/mol

Synonyms: Sodium Diethylhexyl Sulfosuccinate, Dioctyl Sodium Sulfosuccinate, Docusate Sodium, Sodium Dioctyl Sulfosuccinate, Aerosol OT (common trade reference), AOT Surfactant, Sodium Bis(2-ethylhexyl) Sulfosuccinate, Sodium 2-Ethylhexyl Sulfosuccinate (common naming), Wetting Agent DOSS, Anionic Wetting Agent, Sodium Dioctyl Sulfosuccinate Surfactant, DOSS, Sodium Diethylhexyl Sulfosuccinate, SODIUM DIETHYLHEXYL SULFOSUCCINATE, Sodium diethylhexyl sulfosuccinate, Dioctyl Sodium Sulfosuccinate, Dioctyl sulfosuccinate sodium salt, Dioctyl sulfosuccinate sodium, Sodium Dioctyl Sulfosuccinate, Sodium dioctyl sulfosuccinate, DOSS, DOSS (Sodium Dioctyl Sulfosuccinate), Docusate Sodium, Docusate sodium, Docusate, Docusate (sodium), Docusate sodium (INN), Docusate sodium (USAN), Docusate Sodium (USP), Docusate Sodium (EP), Docusate Sodium (BP), Dioctyl Sulfosuccinate Sodium Salt, Dioctyl Sulfosuccinate (Sodium Salt), Sodium Salt of Dioctyl Sulfosuccinate, Sulfosuccinic Acid, Dioctyl Ester, Sodium Salt, Sulfosuccinate (Dioctyl) Sodium Salt, Sodium Di(2-ethylhexyl) Sulfosuccinate, Sodium di(2-ethylhexyl) sulfosuccinate, Di(2-ethylhexyl) Sulfosuccinate Sodium Salt, Bis(2-ethylhexyl) Sulfosuccinate Sodium Salt, Bis(2-ethylhexyl) sodium sulfosuccinate, Sodium Bis(2-ethylhexyl) Sulfosuccinate, 2-Ethylhexyl Sulfosuccinate Sodium Salt (common shorthand), AOT, AOT (surfactant), Aerosol OT, AEROSOL OT, Aerosol-OT, Aerosol OT (surfactant), Aerosol OT (AOT), OT (Aerosol OT) (short), Sodium AOT, AOT sodium salt, Sulfosuccinate Surfactant (DOSS), Anionic Surfactant (DOSS), Wetting Agent (DOSS), Wetting Agent (AOT), Dispersant (DOSS),

APPLICATIONS


Sodium Diethylhexyl Sulfosuccinate is used in shampoos and body washes as a wetting agent to improve quick foam wetting and rinse behavior in compatible systems.
Sodium Diethylhexyl Sulfosuccinate is incorporated into sulfate-free cleansing systems to improve wetting of hair and skin and enhance soil removal.
Sodium Diethylhexyl Sulfosuccinate is used in facial cleansers at optimized levels to improve wetting and cleansing while managing mildness.

Sodium Diethylhexyl Sulfosuccinate is used in micellar and cleansing water products to improve wetting and removal of oils and light makeup in compatible designs.
Sodium Diethylhexyl Sulfosuccinate is incorporated into makeup removers to improve penetration into oily residues and improve wipe-off performance.
Sodium Diethylhexyl Sulfosuccinate is used in cleansing wipes to improve wetting of the wipe substrate and improve cleaning efficiency.

Sodium Diethylhexyl Sulfosuccinate is used in topical pharmaceutical formulations as a surfactant and solubilizer in compatible dosage forms.
Sodium Diethylhexyl Sulfosuccinate is incorporated into oral softening and wetting systems, and Sodium Diethylhexyl Sulfosuccinate is also used as a stool softener active in regulated medicines under the name docusate sodium.
Sodium Diethylhexyl Sulfosuccinate is used in suspensions and emulsions to improve wetting of powders and dispersion stability in compatible pharma systems.

Sodium Diethylhexyl Sulfosuccinate is used in tablet and capsule manufacturing as a wetting agent to improve dissolution and uniform wetting of hydrophobic powders.
Sodium Diethylhexyl Sulfosuccinate is incorporated into granulation and coating processes to improve wetting and dispersion of active ingredients.
Sodium Diethylhexyl Sulfosuccinate is used in drug delivery research where strong wetting improves bioavailability of poorly wetting actives.

Sodium Diethylhexyl Sulfosuccinate is used in industrial coatings as a wetting agent to improve substrate wetting and reduce defects such as craters.
Sodium Diethylhexyl Sulfosuccinate is incorporated into pigment dispersions to improve wetting of pigment surfaces and reduce milling energy.
Sodium Diethylhexyl Sulfosuccinate is used in waterborne coatings to improve flow and leveling through better wetting.

Sodium Diethylhexyl Sulfosuccinate is used in inks to improve penetration, wetting, and print uniformity on porous substrates.
Sodium Diethylhexyl Sulfosuccinate is incorporated into flexographic and gravure inks to reduce surface tension and improve dot formation.
Sodium Diethylhexyl Sulfosuccinate is used in textile printing to improve wetting of fibers and uniform dye or pigment deposition.

Sodium Diethylhexyl Sulfosuccinate is used in agrochemical formulations as a wetting and spreading agent to improve coverage on leaves and plant surfaces.
Sodium Diethylhexyl Sulfosuccinate is incorporated into spray adjuvants to improve droplet spreading and penetration.
Sodium Diethylhexyl Sulfosuccinate is used in pesticide formulations to improve wetting of hydrophobic actives and improve efficacy in compatible systems.

Sodium Diethylhexyl Sulfosuccinate is used in emulsion polymerization as a surfactant to stabilize latex particle formation in compatible polymer systems.
Sodium Diethylhexyl Sulfosuccinate is incorporated into acrylic and styrene-acrylic latex manufacture as a high-performance emulsifier.
Sodium Diethylhexyl Sulfosuccinate is used in polymer dispersions where rapid wetting and stable particle formation are required.

Sodium Diethylhexyl Sulfosuccinate is used in mineral processing and flotation as a wetting agent and dispersant in selected processes.
Sodium Diethylhexyl Sulfosuccinate is incorporated into slurry systems to improve dispersion and reduce surface tension effects.
Sodium Diethylhexyl Sulfosuccinate is used in laboratory and industrial processes where rapid wetting and penetration are critical.

Sodium Diethylhexyl Sulfosuccinate is valued because Sodium Diethylhexyl Sulfosuccinate provides extremely efficient wetting and surface tension reduction, enabling better dispersion, penetration, and process robustness across many product types.

Sodium Diethylhexyl Sulfosuccinate is used as an anionic surfactant and wetting agent in many formulations.
Sodium Diethylhexyl Sulfosuccinate is used to rapidly reduce surface tension and improve substrate wetting.
Sodium Diethylhexyl Sulfosuccinate supports fast penetration of liquids into porous materials.

Sodium Diethylhexyl Sulfosuccinate is used in personal care products as a wetting and solubilizing surfactant in some systems.
Sodium Diethylhexyl Sulfosuccinate supports improved wetting and foam control in cleansers.
Sodium Diethylhexyl Sulfosuccinate helps improve rinseability and reduces residue in suitable formulations.

Sodium Diethylhexyl Sulfosuccinate is used in shampoos as a wetting agent to improve water spreading on hair.
Sodium Diethylhexyl Sulfosuccinate supports fast distribution of cleansing solution through hair fiber bundles.
Sodium Diethylhexyl Sulfosuccinate helps improve cleansing efficiency by improving wetting of oily soils.

Sodium Diethylhexyl Sulfosuccinate is used in body washes to improve wetting and soil removal at low use levels.
Sodium Diethylhexyl Sulfosuccinate supports faster wetting of skin and better distribution of surfactant solution.
Sodium Diethylhexyl Sulfosuccinate helps improve consumer-perceived rinse clean feel in some systems.

Sodium Diethylhexyl Sulfosuccinate is used in facial cleansers to improve wetting of sunscreen and sebum films.
Sodium Diethylhexyl Sulfosuccinate supports rapid soil penetration and emulsification.
Sodium Diethylhexyl Sulfosuccinate helps improve cleansing at low surfactant load in mild systems.

Sodium Diethylhexyl Sulfosuccinate is used in micellar cleansing waters as a wetting and solubilizing aid in some designs.
Sodium Diethylhexyl Sulfosuccinate supports formation of small micelles that lift oils.
Sodium Diethylhexyl Sulfosuccinate helps improve removal of long-wear makeup in compatible systems.

Sodium Diethylhexyl Sulfosuccinate is used in oral care products in niche systems as a wetting agent.
Sodium Diethylhexyl Sulfosuccinate supports dispersion of flavors and actives in some mouth rinses.
Sodium Diethylhexyl Sulfosuccinate helps wet tooth surfaces and improves ingredient distribution.

Sodium Diethylhexyl Sulfosuccinate is used in pharmaceutical products as a wetting agent and solubilizer.
Sodium Diethylhexyl Sulfosuccinate supports improved wetting of poorly wettable powders in suspensions.
Sodium Diethylhexyl Sulfosuccinate helps improve dissolution and bioavailability of some actives in oral dosage forms.

Sodium Diethylhexyl Sulfosuccinate is used as a stool softener active in approved pharmaceutical laxative products in some markets.
Sodium Diethylhexyl Sulfosuccinate supports softening of stool by increasing water penetration into fecal mass.
Sodium Diethylhexyl Sulfosuccinate helps relieve constipation under labeled medical guidance.

Sodium Diethylhexyl Sulfosuccinate is used in tablet manufacturing as a wetting aid to improve disintegration.
Sodium Diethylhexyl Sulfosuccinate supports faster water uptake into compressed tablets.
Sodium Diethylhexyl Sulfosuccinate helps improve release of active ingredients in some formulations.

Sodium Diethylhexyl Sulfosuccinate is used in topical pharmaceutical preparations as a wetting and dispersion aid in some systems.
Sodium Diethylhexyl Sulfosuccinate supports improved spreading and wetting on skin.
Sodium Diethylhexyl Sulfosuccinate helps improve dispersion of insoluble actives in creams and gels.

Sodium Diethylhexyl Sulfosuccinate is used in paints and coatings as a wetting agent and dispersant.
Sodium Diethylhexyl Sulfosuccinate supports pigment wetting and rapid dispersion during grinding.
Sodium Diethylhexyl Sulfosuccinate helps reduce craters and improve leveling by lowering surface tension.

Sodium Diethylhexyl Sulfosuccinate is used in water-based inks as a wetting agent to improve print quality.
Sodium Diethylhexyl Sulfosuccinate supports rapid wetting of paper and film substrates.
Sodium Diethylhexyl Sulfosuccinate helps reduce mottle and improves color uniformity in prints.

Sodium Diethylhexyl Sulfosuccinate is used in pigment dispersions to improve wetting of hydrophobic pigments.
Sodium Diethylhexyl Sulfosuccinate supports reduced agglomeration and improved color strength.
Sodium Diethylhexyl Sulfosuccinate helps improve dispersion stability in aqueous systems.

Sodium Diethylhexyl Sulfosuccinate is used in emulsion polymerization as a surfactant and emulsifier.
Sodium Diethylhexyl Sulfosuccinate supports stable latex formation in acrylic and styrene-based emulsions.
Sodium Diethylhexyl Sulfosuccinate helps control particle size and latex stability during polymerization.

Sodium Diethylhexyl Sulfosuccinate is used in construction chemicals to improve wetting and dispersion in cement additives.
Sodium Diethylhexyl Sulfosuccinate supports uniform distribution of admixtures in cement slurries.
Sodium Diethylhexyl Sulfosuccinate helps improve penetration of water into powders for faster mixing.

Sodium Diethylhexyl Sulfosuccinate is used in agrochemical formulations as a wetting agent and penetrant.
Sodium Diethylhexyl Sulfosuccinate supports better spreading of spray droplets on leaf surfaces.
Sodium Diethylhexyl Sulfosuccinate helps improve efficacy of pesticides by improving coverage and penetration.

Sodium Diethylhexyl Sulfosuccinate is used in seed treatment formulations to improve wetting and coating uniformity.
Sodium Diethylhexyl Sulfosuccinate supports better adhesion of actives to seed surfaces.
Sodium Diethylhexyl Sulfosuccinate helps improve uniform distribution of treatment chemicals.

Sodium Diethylhexyl Sulfosuccinate is used in textile processing as a wetting agent in scouring and dyeing.
Sodium Diethylhexyl Sulfosuccinate supports rapid wetting of fibers and improved dye bath penetration.
Sodium Diethylhexyl Sulfosuccinate helps improve leveling and reduce streaks in textile dyeing.

Sodium Diethylhexyl Sulfosuccinate is used in leather processing as a wetting and dispersing aid in aqueous steps.
Sodium Diethylhexyl Sulfosuccinate supports penetration of aqueous chemicals into hides.
Sodium Diethylhexyl Sulfosuccinate helps improve uniformity of processing baths.

Sodium Diethylhexyl Sulfosuccinate is used in pulp and paper processing as a wetting agent and defoaming-related surfactant in some systems.
Sodium Diethylhexyl Sulfosuccinate supports improved wetting of fibers and fillers.
Sodium Diethylhexyl Sulfosuccinate helps control foam behavior by tuning surface activity at low levels.

Sodium Diethylhexyl Sulfosuccinate is used in household cleaners as a super-wetting agent for hard surfaces.
Sodium Diethylhexyl Sulfosuccinate supports fast spreading on glass, tile, and plastic.
Sodium Diethylhexyl Sulfosuccinate helps lift oily films by rapid wetting and emulsification.

Sodium Diethylhexyl Sulfosuccinate is used in glass and mirror cleaners to reduce beading and improve streak-free drying.
Sodium Diethylhexyl Sulfosuccinate supports uniform film formation during wiping.
Sodium Diethylhexyl Sulfosuccinate helps improve clarity by preventing droplet marks.

Sodium Diethylhexyl Sulfosuccinate is used in carpet and upholstery cleaners to improve wetting and soil penetration.
Sodium Diethylhexyl Sulfosuccinate supports faster penetration into textile fibers and stains.
Sodium Diethylhexyl Sulfosuccinate helps improve extraction cleaning efficiency.

Sodium Diethylhexyl Sulfosuccinate is used in industrial cleaning to improve wetting of powders and solids during mixing.
Sodium Diethylhexyl Sulfosuccinate supports faster dissolution and dispersion of powders in process tanks.
Sodium Diethylhexyl Sulfosuccinate helps reduce fish-eyes and floating powders in production.

Sodium Diethylhexyl Sulfosuccinate is used in mining and mineral processing as a wetting agent in slurry handling in some systems.
Sodium Diethylhexyl Sulfosuccinate supports improved wetting of hydrophobic particles.
Sodium Diethylhexyl Sulfosuccinate helps improve dispersion and reduce dusting in mineral slurries.

Sodium Diethylhexyl Sulfosuccinate is used in laboratory research as a surfactant for wetting studies and interfacial science.
Sodium Diethylhexyl Sulfosuccinate supports model systems that require rapid surface tension reduction.
Sodium Diethylhexyl Sulfosuccinate helps create reproducible wetting behavior in experiments.

Sodium Diethylhexyl Sulfosuccinate is used in nanoparticle synthesis and dispersion to control surface tension and particle wetting.
Sodium Diethylhexyl Sulfosuccinate supports stable dispersions in some aqueous nanoparticle systems.
Sodium Diethylhexyl Sulfosuccinate helps reduce aggregation by improving wetting and dispersant action.

Sodium Diethylhexyl Sulfosuccinate is used in membrane filtration and water treatment research to modify wetting of membranes.
Sodium Diethylhexyl Sulfosuccinate supports improved wetting of hydrophobic membrane surfaces.
Sodium Diethylhexyl Sulfosuccinate helps reduce fouling in some test systems by improving surface wetting.

Sodium Diethylhexyl Sulfosuccinate is used in emulsion and microemulsion formulation research as a strong wetting surfactant.
Sodium Diethylhexyl Sulfosuccinate supports formation of small droplets by lowering interfacial tension.
Sodium Diethylhexyl Sulfosuccinate helps improve stability of emulsified systems in controlled studies.

Sodium Diethylhexyl Sulfosuccinate is used in quality control labs to benchmark wetting agent performance across batches.
Sodium Diethylhexyl Sulfosuccinate supports surface tension testing and critical micelle concentration checks.
Sodium Diethylhexyl Sulfosuccinate helps ensure consistent performance of wetting-agent raw materials.

Sodium Diethylhexyl Sulfosuccinate is used in production troubleshooting to fix poor wetting, cratering, or fish-eye defects.
Sodium Diethylhexyl Sulfosuccinate supports rapid surface tension reduction to eliminate wetting defects.
Sodium Diethylhexyl Sulfosuccinate helps restore uniform coating and printing performance when used correctly.

DESCRIPTION


Sodium Diethylhexyl Sulfosuccinate is an anionic sulfosuccinate surfactant with two branched 2-ethylhexyl groups, and this structure gives Sodium Diethylhexyl Sulfosuccinate strong wetting power and surface activity.
Sodium Diethylhexyl Sulfosuccinate is one of the most effective wetting agents used in industry, and Sodium Diethylhexyl Sulfosuccinate can dramatically reduce water surface tension at low concentrations.
Sodium Diethylhexyl Sulfosuccinate is typically supplied as a solution or paste, and carrier choice influences handling, freezing behavior, and compatibility with the final formulation.

Sodium Diethylhexyl Sulfosuccinate can be more irritating than some mild surfactants at higher levels, so Sodium Diethylhexyl Sulfosuccinate is commonly used at low concentrations as a functional additive rather than as a primary cleanser.
Sodium Diethylhexyl Sulfosuccinate is compatible with many surfactants, polymers, and solvents, but high electrolyte levels and extreme pH can influence clarity and stability.
Sodium Diethylhexyl Sulfosuccinate should be selected with appropriate grade and purity, especially for pharmaceutical and personal care applications where impurity limits and solvent carriers matter.

Sodium Diethylhexyl Sulfosuccinate should be stored in tightly closed containers in a cool, dry place and protected from freezing if supplied in water-based solutions.
Sodium Diethylhexyl Sulfosuccinate spills can create significant slip hazards, and surfaces should be cleaned thoroughly after spills.
Sodium Diethylhexyl Sulfosuccinate should be used according to supplier specifications and applicable regulations for the intended market and product category.

Sodium Diethylhexyl Sulfosuccinate is an anionic surfactant commonly known as Docusate Sodium in pharmaceutical contexts.
Sodium Diethylhexyl Sulfosuccinate is widely recognized as a strong wetting agent that rapidly lowers surface tension.
Sodium Diethylhexyl Sulfosuccinate is typically supplied as a waxy solid, paste, or solution depending on grade and concentration.

Sodium Diethylhexyl Sulfosuccinate has a sulfosuccinate head group and branched hydrophobic tails that promote strong surface activity.
Sodium Diethylhexyl Sulfosuccinate is effective at low levels, which makes it valuable for wetting and dispersing tasks.
Sodium Diethylhexyl Sulfosuccinate can produce low foam compared with some other anionic surfactants, depending on formulation.

Sodium Diethylhexyl Sulfosuccinate is soluble in water to varying degrees and is also soluble in alcohols and some organic solvents.
Sodium Diethylhexyl Sulfosuccinate performance depends on electrolyte level, pH, and presence of other surfactants and polymers.
Sodium Diethylhexyl Sulfosuccinate is often used in blends to balance wetting, detergency, and foam.

Sodium Diethylhexyl Sulfosuccinate is used in pharmaceuticals as a wetting agent and also as a stool softener active in approved products.
Sodium Diethylhexyl Sulfosuccinate use levels and permitted applications depend on regulatory frameworks and product category.
Sodium Diethylhexyl Sulfosuccinate should be used within compliant limits and with appropriate labeling in regulated products.

PROPERTIES


Chemical Formula: C20H37NaO7S
Molecular Weight: 444.56 g/mol
Common Name: Sodium Diethylhexyl Sulfosuccinate (Docusate Sodium, DOSS)
Chemical Type: Anionic sulfosuccinate surfactant; high-efficiency wetting agent
Appearance: Clear to slightly hazy liquid or viscous solution (as supplied; grade dependent)
Odor: Mild characteristic odor (grade dependent)
Solubility: Dispersible in water; soluble behavior depends on carrier and concentration; soluble in alcohols and some solvents (grade dependent)
Surface Activity: Very strong surface tension reduction and fast wetting
Foam: Low to moderate foam compared with many anionics (system dependent)
Wetting: Excellent wetting and penetration of porous substrates
Compatibility: Broad compatibility; stability affected by extreme pH and high electrolytes (system dependent)
Stability: Stable under recommended storage; protect from freezing and contamination
Storage Temperature: 10–30°C, tightly closed; avoid frost for aqueous grades
Shelf Life: Typically 12–24 months in original sealed packaging (supplier dependent)

FIRST AID


Inhalation:
Move to fresh air if mists are inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing aerosols during spraying and high-shear mixing.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a significant amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
Consider gastrointestinal effects if large ingestion occurred because docusate sodium has laxative activity.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE


Handling:
Use appropriate PPE including gloves and safety glasses, especially when handling concentrated solutions.
Avoid contact with eyes and prolonged skin contact.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use general ventilation for normal handling.
Use local exhaust if mists may be generated during mixing or spraying.
Avoid aerosol formation in enclosed spaces without proper ventilation.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from freezing if supplied in water-based solutions to prevent phase separation.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Contain spills and absorb with inert material.
Clean surfaces thoroughly because sulfosuccinate surfactants can create serious slip hazards.
Dispose of waste according to local regulations and facility procedures.

Handling Precautions:
Use Sodium Diethylhexyl Sulfosuccinate at optimized low levels to achieve wetting and dispersion without excessive irritation or foam changes.
Verify compatibility with electrolytes, preservatives, and fragrance systems to prevent haze or phase separation.
Rotate stock using FIFO practices to maintain consistent quality and predictable wetting performance.

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