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Sodium Diethylhexyl Sulfosuccinate serves as a pharmaceutical excipient, tablet wetting agent, emulsifier, suspension stabilizer, and, in specific formulations, as the active ingredient in stool softener products.
Sodium Diethylhexyl Sulfosuccinate facilitates ingredient dispersion and improves formulation uniformity in liquid and semi-solid dosage forms.
Sodium Diethylhexyl Sulfosuccinate is also employed in cosmetics and personal care formulations such as cleansing products, shampoos, skin cleansers, facial washes, and specialty hygiene products where efficient wetting, emulsification, and cleansing performance are required.
CAS Number: 577-11-7
EC Number: 209-406-4
Molecular Formula: C₂₀H₃₇NaO₇S
Molecular Weight: 444.56 g/mol
SYNONYMS:
SCHEMBL58059, sodium diethylhexyl sulfosuccinate, DSS,DOCUSATE SODIUM,AOT,SODIUM DIOCTYL SULFOSUCCINATE,DIOCTYL SODIUM SULFOSUCCINATE,DOSS,Docusate,Sodium Docusate,OT-75,DIETHYLHEXYL SODIUM SULFOSUCCINATE, elfanol883,di-n-octylsodiumsulfosuccinate,SULFONATEDALIPHATICPOLYESTER,dioktylestersulfojantaranusodneho, DOSS, DOS, Docusate Sodium, Sodium Diethylhexyl Sulfosuccinate, Aerosol OT, Texin DOS 75, Mackanate DOS-75, CAS number: 577-11-7, Dioctyl sodium sulphosuccinate, Docusate sodium, Sodium dioctylsulfosuccinate, sulphosuccinic acid bis-2-ethylhexyl ester, PenetratingagentT, DICAPRYL SODIUM SULFOSUCCINATE, di-n-octylsodiumsulfosuccinate, dioktylestersulfojantaranusodneho, 1,4-dioctoxy-1,4-dioxobutane-2-sulfonic acid
Sodium Diethylhexyl Sulfosuccinate is an anionic surfactant, compatible with other anionic, amphoteric and non-ionic surfactants.
Sodium Diethylhexyl Sulfosuccinate is highly suitable for body washes / cleansing formulations with high oil contents (20-50%).
Due to the structural design, Sodium Diethylhexyl Sulfosuccinate's hydrophobicity allows it to hold on to high oil content and creating lamillar structures, to give the consumers new creamy texture of the product, but yet no sacrifising on the foaming performance, at the same time, resulting a caring sensory during and after wash.
Sodium Diethylhexyl Sulfosuccinate is a sodium salt of the diester of 2-ethylhexyl alcoholand sulfosuccinic acid.
Sodium Diethylhexyl Sulfosuccinate (DOSS) is a highly effective anionic surfactant recognized for its exceptional wetting, emulsifying, dispersing, and detergent properties.
Sodium Diethylhexyl Sulfosuccinate is one of the most powerful surface tension-reducing agents available and is widely used in industrial, pharmaceutical, cosmetic, agricultural, textile, coating, and specialty chemical formulations.
Sodium Diethylhexyl Sulfosuccinate contains two hydrophobic 2-ethylhexyl chains attached to a sulfosuccinate backbone, providing an excellent balance between hydrophilic and lipophilic properties.
This unique molecular structure of Sodium Diethylhexyl Sulfosuccinate enables rapid adsorption at liquid-solid and liquid-air interfaces, resulting in outstanding wetting efficiency and fast penetration into porous materials.
Sodium Diethylhexyl Sulfosuccinate (which is a common name for Diethylhexyl Sodium Sulfosuccinate) is a surfactant featuring very good emulsifying, wetting and dispersing properties.
Sodium Diethylhexyl Sulfosuccinate is an ingredient of a number of cosmetic formulations.
Sodium Diethylhexyl Sulfosuccinate is the INCI name for di(2-ethylhexyl) sulfoccinate sodium salt.
Other valid chemical names of Sodium Diethylhexyl Sulfosuccinate are sodium salt of di(2-ethylhexyl) alcohol ester and sulfosuccinic acid or docusate sodium.
The CAS number of Sodium Diethylhexyl Sulfosuccinate is 577-11-7.
In products, the compound primarily acts as an emulsifier, wetting agent and dispersing substance.
Sodium Diethylhexyl Sulfosuccinate is a potent anionic surfactant and wetting agent that significantly lowers the surface tension of liquids.
Sodium Diethylhexyl Sulfosuccinate, a derivative of succinic acid, is a surfactant used in cosmetic formulations.
Sodium Diethylhexyl Sulfosuccinate is a surfactant and emulsifying agent widely used in cosmetics to obtain products of the desired quality.
Sodium Diethylhexyl Sulfosuccinate enhances the water solubility of various other ingredients in a formulation.
Further, Sodium Diethylhexyl Sulfosuccinate is also a great foaming and dispersing agent.
In its raw form, Diethylhexyl Sodium Sulfosuccinate takes the form of a waxy solid that is colorless to light yellow.
Sodium Diethylhexyl Sulfosuccinate is largely safe for use and does not negatively impact human health.
Sodium Diethylhexyl Sulfosuccinate is the INCI name of di(2-ethylhexyl) sulfoccinate sodium salt and has the chemical formula C20H37NaO7S.
Sodium Diethylhexyl Sulfosuccinate is an anionic surfactant with a concentrated active substance content (70%) in propylene glycol (INCI name: Diethylhexyl Sodium Sulfosuccinate).
Sodium Diethylhexyl Sulfosuccinate is a surfactant with limited water solubility.
Due to its unique molecular structure, Sodium Diethylhexyl Sulfosuccinate has a strong wetting effect on highly hydrophobic materials such as anthracite carbon.
Sodium diethylhexyl sulfosuccinate is a chemical substance, also known as sodium di (2-ethylhexyl) succinate sulfonate, with the molecular formula C20H36O7SNa.
Sodium Diethylhexyl Sulfosuccinate known as docusate sodium or diethylhexyl sodium sulfosuccinate, is the sodium salt of the diester of 2-ethylhexyl alcohol and sulfosuccinic acid.
Sodium Diethylhexyl Sulfosuccinate belongs to the class of dialkyl sulfosuccinate salts being essentially incorporated as surfactant in cosmetic products and long-established in food industry.
Traditionally, Sodium Diethylhexyl Sulfosuccinate has been prescribed or offered as the over-the-counter laxative or stool softener for a wide range of vertebrates.
Sodium Diethylhexyl Sulfosuccinate known as docusate sodium or diethylhexyl sodium sulfosuccinate, is the sodium salt of the diester of 2-ethylhexyl alcohol and sulfosuccinic acid.
Sodium Diethylhexyl Sulfosuccinate belongs to the class of dialkyl sulfosuccinate salts being essentially incorporated as surfactant in cosmetic products and long-established in food industry.
Traditionally, Sodium Diethylhexyl Sulfosuccinate has been prescribed or offered as the over-the-counter laxative or stool softener for a wide range of vertebrates.
Sodium Diethylhexyl Sulfosuccinate is a versatile surfactant widely utilized in various industries due to its excellent emulsifying and wetting properties.
Sodium Diethylhexyl Sulfosuccinate, often recognized for its ability to enhance the solubility of hydrophobic substances, is particularly valuable in the formulation of pharmaceuticals, cosmetics, and personal care products.
Its unique structure allows Sodium Diethylhexyl Sulfosuccinate to effectively stabilize emulsions, making it an ideal choice for creams, lotions, and ointments.
Additionally, Sodium Diethylhexyl Sulfosuccinate serves as a dispersing agent in agricultural formulations, improving the efficacy of pesticides and herbicides by ensuring uniform distribution.
In the realm of research and development, Sodium Diethylhexyl Sulfosuccinate is employed in laboratory settings for its ability to facilitate the solubilization of various compounds, aiding in the formulation of complex mixtures.
Its low toxicity and biodegradable nature make Sodium Diethylhexyl Sulfosuccinate a preferred option for environmentally conscious formulations.
With its multifunctional capabilities, Sodium Diethylhexyl Sulfosuccinate stands out as a reliable ingredient that enhances product performance while meeting regulatory standards.
Sodium Diethylhexyl Sulfosuccinate or Docusate sodium or Diethylhexyl Sodium Sulfosuccinate is a chemical compound, the sodium salt of docusate.
Sodium Diethylhexyl Sulfosuccinate is a wetting and emulsifying agent that is slowly soluble in water, having a solubility of 1 g in 70 ml of water.
Sodium Diethylhexyl Sulfosuccinate functions as a wetting agent in fumaric acid-containing powdered fruit drinks to help the acid dissolve in water.
Sodium Diethylhexyl Sulfosuccinate is an organic sodium salt.
Sodium Diethylhexyl Sulfosuccinate is an odorless, colorless to white waxy solid.
Sodium Diethylhexyl Sulfosuccinate sinks and mixes slowly with water.
Sodium Diethylhexyl Sulfosuccinate mixes slowly with water.
Sodium Diethylhexyl Sulfosuccinate is a highly effective anionic surfactant known for its exceptional wetting, emulsifying, and dispersing properties.
Sodium Diethylhexyl Sulfosuccinate is one of the most efficient wetting agents available and can significantly reduce surface tension at very low concentrations.
USES and APPLICATIONS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is widely used as a high-performance wetting agent in industrial formulations where rapid penetration of aqueous solutions is essential.
Sodium Diethylhexyl Sulfosuccinate improves the wetting of powders, pigments, mineral fillers, fibers, textiles, and porous materials, enhancing manufacturing efficiency and product consistency.
In the coatings and paints industry, Sodium Diethylhexyl Sulfosuccinate functions as a wetting and dispersing agent that promotes pigment distribution, improves color development, reduces grinding time, minimizes foam generation, and enhances coating uniformity.
Sodium Diethylhexyl Sulfosuccinate contributes to smoother finishes, better substrate coverage, and improved long-term coating stability.
Because of its superior performance at very low concentrations, Sodium Diethylhexyl Sulfosuccinate is extensively utilized in products requiring rapid surface wetting, improved dispersion, stable emulsification, and efficient cleaning performance.
Sodium Diethylhexyl Sulfosuccinate is also used as a pharmaceutical excipient, laboratory reagent, and processing aid in numerous manufacturing industries.
Within the textile industry, Sodium Diethylhexyl Sulfosuccinate is incorporated into dyeing, scouring, bleaching, washing, and finishing formulations to improve fiber wetting, accelerate chemical penetration, enhance dye uniformity, and facilitate the removal of oils and processing residues from textile materials.
Sodium Diethylhexyl Sulfosuccinate is extensively used in agricultural formulations, including pesticide emulsions, herbicide concentrates, fungicides, foliar fertilizers, and spray adjuvants.
Sodium Diethylhexyl Sulfosuccinate's excellent spreading and wetting properties improve coverage of plant surfaces, enhance active ingredient distribution, and increase the effectiveness of agricultural treatments.
In pharmaceutical applications, Sodium Diethylhexyl Sulfosuccinate serves as a pharmaceutical excipient, tablet wetting agent, emulsifier, suspension stabilizer, and, in specific formulations, as the active ingredient in stool softener products.
Sodium Diethylhexyl Sulfosuccinate facilitates ingredient dispersion and improves formulation uniformity in liquid and semi-solid dosage forms.
Sodium Diethylhexyl Sulfosuccinate is also employed in cosmetics and personal care formulations such as cleansing products, shampoos, skin cleansers, facial washes, and specialty hygiene products where efficient wetting, emulsification, and cleansing performance are required.
Industrial applications of Sodium Diethylhexyl Sulfosuccinate further include paper manufacturing, leather processing, polymer emulsions, adhesives, construction chemicals, ceramic slurries, metal treatment, latex processing, laboratory reagents, and specialty cleaning formulations requiring outstanding surface activity.
Sodium Diethylhexyl Sulfosuccinate is widely used in personal care, pharmaceuticals (as a laxative in docusate sodium), industrial cleaning, textile processing, paper manufacturing, agriculture, coatings, and inks.
First of all, as an emulsifier, Sodium Diethylhexyl Sulfosuccinate facilitates the generation of an emulsion, i.e. helps to combine the particles of two immiscible phases.
Sodium Diethylhexyl Sulfosuccinate is essential as appropriate emulsifiers are required to obtain a product of the desired quality.
A vast majority of cosmetics as well as compositions of ingredients with industrial applications come as emulsions.
In those products, Sodium Diethylhexyl Sulfosuccinate acts as what is known as hydrotrope, i.e. a substance added to improve the clarity.
Sodium Diethylhexyl Sulfosuccinate also enhances the generation of stable foam – it is a foaming substance.
Sodium Diethylhexyl Sulfosuccinate improves the quality of foam in a mixture with non-ionic surfactants.
Due to its foaming properties, Diethylhexyl Sodium Sulfosuccinate is a very good washing substance.
Sodium Diethylhexyl Sulfosuccinate effectively removes impurities from the skin and hair surface, while remaining extremely gentle for the skin and mucous membranes.
As a surfactant, Sodium Diethylhexyl Sulfosuccinate increases the water solubility of some substances.
Due to its molecular structure, Sodium Diethylhexyl Sulfosuccinate effectively lowers the interfacial tension.
Sodium Diethylhexyl Sulfosuccinate facilitates the contact of a liquid with the surface to be wetted.
A low concentration of Sodium Diethylhexyl Sulfosuccinate is sufficient to effectively lower the surface tension.
The wetting effect of Sodium Diethylhexyl Sulfosuccinate is used mainly in the textile industry.
Sodium Diethylhexyl Sulfosuccinate boosts the effectiveness of detergents used e.g. in fibre washing processes.
As a wetting agent, Sodium Diethylhexyl Sulfosuccinate is also used in paints, adhesives or varnishes.
As a dispersant, Sodium Diethylhexyl Sulfosuccinate is used to disperse pigments in printer inks.
Besides dispersing them in the dispersion medium, Sodium Diethylhexyl Sulfosuccinate improves their penetration.
The plastics industry also uses Sodium Diethylhexyl Sulfosuccinate as an additive for dispersing dyes in processing masses.
The use of Sodium Diethylhexyl Sulfosuccinate in plant protection products provides for their proper wetting and increases the rate of pesticide absorption in plants.
In the construction industry, Sodium Diethylhexyl Sulfosuccinate acts as a wetting agent for cement grains and is also used in anti-adhesive additives, which prevent concrete from sticking to the mould, thus facilitating separation.
Sodium Diethylhexyl Sulfosuccinate is also used as a drug and as an excipient in pharmaceutical preparations.
In cosmetic formulations Sodium Diethylhexyl Sulfosuccinate acts as emulsifier (changes the interfacial tension of liquids like water and oil so that they can be mixed together), furthermore as surfactant.
Sodium Diethylhexyl Sulfosuccinate is used as a stabilizing agent on gums at not more than 0.5% by weight of the gum.
Sodium Diethylhexyl Sulfosuccinate is used as a flavor potentiator in canned milk where it improves and maintains the flavor of the sterilized milk during storage.
Sodium Diethylhexyl Sulfosuccinate also functions as a processing aid in the manufacture of unrefined sugar.
Sodium Diethylhexyl Sulfosuccinate is also termed sodium dioctylsulfosuccinate.
Sodium Diethylhexyl Sulfosuccinate is a mild surfactant used as a cleans ing agent.
Sodium Diethylhexyl Sulfosuccinate, used for the treatment of constipation, acting as a laxative or stool softener.
Sodium Diethylhexyl Sulfosuccinate is also used in the synthesis of electrospun fibres for tailored and controlled antibiotic drug release.
Sodium Diethylhexyl Sulfosuccinate forms reverse micelles in hydrocarbon solvents; Suitable for the solubilization of the major myelin transmembrane proteolipid
Uses of Sodium Diethylhexyl Sulfosuccinate: anticholinergic, treatment of motion sickness
Application of Sodium Diethylhexyl Sulfosuccinate: Fabric rapid penetrating agent, pesticide emulsifier, surfactant, etc.
Sodium Diethylhexyl Sulfosuccinate is used as rapid fabric penetration agent, pesticide emulsifier, detergent, and surfactant in the printing and dyeing industry.
As a rapid penetrating agent, Sodium Diethylhexyl Sulfosuccinate is suitable for the treatment of cotton, linen, viscose and blended products.
The treated fabrics can be bleached or dyed directly, without scouring.
The fabric after printing and dyeing feels soft and plump.
The preparation method of the rapid penetrating agent T aqueous solution is to first add 50 to 100 times of water, leave it overnight, and then stir to dissolve.
Or dissolve Sodium Diethylhexyl Sulfosuccinate with hot water around 90℃.
But Sodium Diethylhexyl Sulfosuccinate's best penetration effect is below 40℃.
Sodium Diethylhexyl Sulfosuccinate is easy to decompose when exposed to alkali at high temperatures.
If there is too much foam during use, defoaming agents such as octanol and tributyl phosphate can be added for defoaming treatment.
Sodium Diethylhexyl Sulfosuccinate is a highly efficient penetrating agent, used to treat cotton, linen, viscose and their blended products.
The treated fabric can be directly bleached or dyed without scouring to improve dyeing defects caused by dead cotton.
The fabric after printing and dyeing also feels softer and fuller.
Sodium Diethylhexyl Sulfosuccinate is also used as pesticide emulsifier, detergent and surfactant.
Sodium Diethylhexyl Sulfosuccinate can also be used as photosensitive material emulsion.
Sodium Diethylhexyl Sulfosuccinate is also used in the chemical, plastics, construction and textile industries.
Sodium Diethylhexyl Sulfosuccinate is primarily utilized in cosmetic science to improve the spreadability of products and to enhance the skin penetration of other active ingredients.
Other uses of Sodium Diethylhexyl Sulfosuccinate: Pesticide industry, emulsifier.
Textile industry: surfactant, penetrating agent and wetting agent below 40°C for cotton, linen, viscose and their blended products.
Leather industry uses of Sodium Diethylhexyl Sulfosuccinate: penetrating agent.
Paint industry uses of Sodium Diethylhexyl Sulfosuccinate: levelling agent.
Photographic material: Sodium Diethylhexyl Sulfosuccinate is used as an emulsifier.
Sodium Diethylhexyl Sulfosuccinate is a versatile surfactant with an excellent wetting property.
Cosmetic: In cosmetic industries, they make use of Sodium Diethylhexyl Sulfosuccinate as an emulsifier, cleansing and hydrotrope.
Applications of Sodium Diethylhexyl Sulfosuccinate: auxiliaries in the textile industry, component of preparations for dewatering of lotation concentrates, dust control, emulsifier in emulsion polymerisation, pigment dispersant, construction industry, component of plant protection products, a component of cosmetic formulations, printing inks.
-Non-cosmetic uses of Sodium Diethylhexyl Sulfosuccinate:
Sodium Diethylhexyl Sulfosuccinate is used as a direct food additive with the limitation of 75 pmm of the final product.
Food and Drug Administration (FDA) has established Sodium Diethylhexyl Sulfosuccinate as a “generally recognized as safe” (GRAS) food additive used as a:
Wetting agent
Processing aid
Solubilizing agent
Emulsifying agent
Dispersing agent
Besides that, Sodium Diethylhexyl Sulfosuccinate is one of the primary components of Corexit 9500A, a chemical dispersant, which was used on the incident of Deepwater Horizon Oil Spill to enhance oil biodegradation.
Sodium Diethylhexyl Sulfosuccinate is also used in the manufacturing of paper and paperboards, pesticides as well as textile industry.
-Effects in cosmetics and industrial products
The main functions of Sodium Diethylhexyl Sulfosuccinate in products:
emulsifier,
dispersant,
wetting agent,
surfactant.
Sodium Diethylhexyl Sulfosuccinate is an ingredient added for example to cosmetic formulations to provide several basic functions.
-Pharmaceutical Applications of Sodium Diethylhexyl Sulfosuccinate:
Sodium Diethylhexyl Sulfosuccinate is widely used as anionic surfactants in pharmaceutical formulations.
Docusate sodium is mainly used in capsule and direct-compression tablet formulations to assist in wetting and dissolution.
WHAT SODIUM DIETHYLHEXYL SULFOSUCCINATE IS USED FOR AND WHERE?
Synthetic anionic detergent
**Medical and pharmaceutical
Sodium Diethylhexyl Sulfosuccinate is an effective remedy for constipation and in particular as a stool softener.
although Psyllium has been shown to be more effective.
Sodium Diethylhexyl Sulfosuccinate is used to treat ear wax plugs that can cause blocked and painful ears and hearing loss.
Methods of removing earwax include the mechanical technique and the use of cerumenolytic agents such as sodium Docusate and sodium bicarbonate.
Sodium Diethylhexyl Sulfosuccinate is administered after urogynecological surgery.
Emulsifier in tablets and pharmaceutical preparations.
**Cosmetics
Cleansing agent.
Sodium Diethylhexyl Sulfosuccinate that cleanses skin without exploiting the surface-active properties that produce a lowering of the surface tension of the stratum corneum.
**Surfactant - Emulsifying agent.
Emulsions are thermodynamically unstable and are used to soothe or soften the skin and emulsify, so they need a specific, stabilising ingredient.
Sodium Diethylhexyl Sulfosuccinate forms a film, lowers the surface tension and makes two immiscible liquids miscible.
A very important factor affecting the stability of the emulsion is the amount of the emulsifying agent.
Emulsifiers have the property of reducing the oil/water or water/oil interfacial tension, improving the stability of the emulsion and also directly influencing the stability, sensory properties and surface tension of sunscreens by modulating the filmometric performance.
**Surfactant - Hydrotrope (solubilizing agents).
Sodium Diethylhexyl Sulfosuccinate has the property of facilitating the miscibility of other compounds that are poorly soluble in water and does not form micelles in the solubilisation process, even with a chemical reaction of complexation or molecular aggregation.
The two fundamental solubilisation factors are the hydrotropic-solute association mediated by the depression of water activity and ionic dissociation.
**Surfactant - Cleansing agent.
Cosmetic products used to cleanse the skin utilise the surface-active action that produces a lowering of the surface tension of the stratum corneum, facilitating the removal of dirt and impurities.
ADVANTAGES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is effectively reduces interfacial tension and wetting angle,
very strong wetting effect on hydrophobic surfaces,
a safe product - due to the presence of propylene glycol and a higher flash point,
increases the effectiveness of detergents during washing,
very good dispersing and emulsifying properties,
COSMETICS INGREDIENTS FUNCTIONS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
*SURFACTANT - HYDROTROPE
*SURFACTANT - EMULSIFYING
*SURFACTANT - CLEANSING
*CLEANSING
BENEFITS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate significantly improves wetting efficiency, allowing liquids to spread rapidly over difficult-to-wet surfaces while enhancing penetration into porous materials.
This reduces processing time and increases formulation effectiveness.
Sodium Diethylhexyl Sulfosuccinate enhances emulsion stability by promoting uniform droplet distribution and preventing phase separation during storage.
Improved dispersion also minimizes particle agglomeration, resulting in more homogeneous products with enhanced appearance and performance.
Sodium Diethylhexyl Sulfosuccinate's exceptional surface activity allows lower surfactant concentrations to achieve high formulation efficiency, reducing raw material consumption and improving overall manufacturing economics.
Sodium Diethylhexyl Sulfosuccinate contributes to improved cleaning performance by facilitating the removal of oils, greases, particulate contaminants, and hydrophobic residues from various surfaces.
Its rapid wetting action also enhances detergent performance in industrial cleaning formulations.
Because of its versatility and excellent compatibility, Sodium Diethylhexyl Sulfosuccinate supports the development of multifunctional products with improved stability, processing characteristics, and application performance across numerous industrial sectors.
PRODUCTS CONTAINING SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is a popular ingredient of products such as:
cosmetics,
excipients in the textile industry,
plant protection products,
anti-adhesive substances,
printing inks,
pigment dispersants.
MAIN FEATURES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Anionic surfactant with exceptional wetting power.
Extremely effective in reducing surface tension.
Effective at very low concentrations.
Excellent emulsifying and dispersing properties.
Soluble in water and organic solvents.
Good hard water tolerance.
Biodegradable
Wide pH stability range
WHAT IS SODIUM DIETHYLHEXYL SULFOSUCCINATE USED FOR?
Sodium Diethylhexyl Sulfosuccinate is primarily used as an effective surfactant and emulsifying agent in the world of cosmetics.
Sodium Diethylhexyl Sulfosuccinate helps to improve the texture and spreadability of products by reducing surface tension, making it ideal for use in shampoos, conditioners, and body washes.
Sodium Diethylhexyl Sulfosuccinate's excellent wetting and dispersing properties ensure even distribution of active ingredients, enhancing the performance of skincare formulations like cleansers, exfoliants, and makeup removers.
Additionally, Sodium Diethylhexyl Sulfosuccinate is used in products designed for sensitive skin due to its mildness and ability to gently cleanse without causing irritation.
ORIGIN of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is made by esterifying maleic anhydride with 2-ethylhexanol to form diethylhexyl maleate.
Sodium Diethylhexyl Sulfosuccinate is then reacted with sodium bisulfite in a sulfonation process to produce Diethylhexyl Sodium Sulfosuccinate.
Sodium Diethylhexyl Sulfosuccinate is purified for cosmetic use.
WHAT DOES SODIUM DIETHYLHEXYL SULFOSUCCINATE DO IN A FORMULATION?
*CLEANSING
*EMULSIFYING
*FOAMING
*HYDROTROPE
*SURFACTANT
SAFETY PROFILE of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is generally considered safe for use in cosmetics and personal care products when used in appropriate concentrations.
Sodium Diethylhexyl Sulfosuccinate is classified as a mild surfactant, which makes it suitable for sensitive skin formulations.
However, at higher concentrations or with prolonged exposure, Sodium Diethylhexyl Sulfosuccinate may cause skin and eye irritation.
Patch testing is recommended.
ALTERNATIVES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
COCAMIDOPROPYL BETAINE
DECYL GLUCOSIDE
SODIUM COCOYL ISETHIONATE
FEATURE of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Wetting
An exceptional wetting agent; Sodium Diethylhexyl Sulfosuccinate significantly reduces surface tension.
Emulsion
An excellent emulsifier for oils and solvents.
Distributing
An effective dispersant for solids and pigments.
Penetration
Superior penetration properties.
Dissolution
Sodium Diethylhexyl Sulfosuccinate dissolves compounds that are insoluble in water.
Surface Activity
Effective at very low concentrations.
Hard Water Tolerance
Sodium Diethylhexyl Sulfosuccinate performs well in hard water.
Biodegradability
Biodegradable
Low foaming
Relatively low foaming compared to other surfactants.
PRIMARY BENEFITS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate facilitates deeper delivery of water-soluble and oil-soluble active ingredients.
Sodium Diethylhexyl Sulfosuccinate ensures uniform coverage by reducing the surface tension of formulations.
Sodium Diethylhexyl Sulfosuccinate acts as a hydrotrope to stabilize complex mixtures containing both Aqua and lipid phases.
PRODUCTS INCLUDE SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Various health and hygiene products’ formulations can include Dioctyl Sodium Sulfosuccinate.
Some of them are as follows:
Shampoo
Face mask
Toner
Body wash
Cleansing gel
Hair color
Eyeliner
Eyebrow pencil
Laundry and dishwashing products
Sodium diethylhexyl sulfosuccinate is used in the formulation of personal care products and as a wetting agent in industrial cleaning formulations.
Sodium Diethylhexyl Sulfosuccinate helps reduce surface tension and enhance product efficiency.
HOW IS SODIUM DIETHYLHEXYL SULFOSUCCINATE MANUFACTURED?
The production process of Sodium Diethylhexyl Sulfosuccinate is initiated by esterification of maleic anhydride through reaction with 2-ethylhexanol to obtain the esterified dioctyl maleate.
Next step is sulfonation; in which dioctyl maleate combines with sodium bisulfite to obtain dioctyl sodium sulfosuccinate as the final product.
The entire reaction occurs under a closed system, and Sodium Diethylhexyl Sulfosuccinate solely opens upon addition of reactants.
CHEMICAL AND PHYSICAL PROPERTIES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is an anionic surfactant harboring a negatively charged head group and a lipophilic tail.
Sodium Diethylhexyl Sulfosuccinate consists of a sulfosuccinate core connected by an ester linkage to an eight-carbon alkyl chain (octyl) on each side.
The chemical structure of Sodium Diethylhexyl Sulfosuccinate has been demonstrated in the following.
THE CHEMICAL STRUCTURE of SODIUM DIETHYLHEXYL SULFOSUCCINATE HAS BEEN DEMONSTRATED:
Docusate sodium is soluble in both water and organic solvents.
Sodium Diethylhexyl Sulfosuccinate is expected to be stable in acidic and neutral solutions and undergoes hydrolysis in alkaline solutions.
FUNCTION(S) of SODIUM DIETHYLHEXYL SULFOSUCCINATE IN COSMETIC PRODUCTS
CLEANSING
Sodium Diethylhexyl Sulfosuccinate cleans skin, hair or teeth
FRAGRANCE FUNCTIONAL
Functional ingredient (excipient) of perfume oils and / or flavours
SURFACTANT - CLEANSING
Surface-active agent to clean skin, hair and / or teeth
SURFACTANT - EMULSIFYING
Sodium Diethylhexyl Sulfosuccinate allows the formation of finely dispersed mixtures of oil and water (emulsions)
SURFACTANT - HYDROTROPE
Sodium Diethylhexyl Sulfosuccinate enhances the solubility of substances in water
PROPERTIES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
The name describes the structure of Sodium Diethylhexyl Sulfosuccinate:
Dioctyl refers to dioctyl alcohol, a fatty alcohol with a chain of 8 carbons, which forms the basis of the molecule.
Sodium indicates the presence of sodium ions (Na+) in the compound.
Sulfosuccinate indicates that a sulphonic acid group has been added to the molecule and that it is a succinic acid derivative.
The synthesis process takes place in different steps:
Preparation of dioctyl alcohol.
Dioctyl alcohol, a fatty alcohol with an 8-carbon chain, is derived from natural sources or synthesised from petrochemical precursors.
Sulphonation.
Dioptyl alcohol is reacted with sulphur trioxide (SO3) in a process called sulphonation.
This involves the addition of a sulphonic acid group to the alcohol, forming dioctyl sulphosuccinic acid.
Neutralisation.
The dioctyl-sulphosuccinic acid is then neutralised with a base, such as sodium hydroxide (NaOH), to form the sodium salt, sodium docusate.
Sodium Diethylhexyl Sulfosuccinate occurs as a colourless to yellowish transparent liquid or white powder that is easily soluble in water.
Sodium Diethylhexyl Sulfosuccinate is incompatible with strong acids, strong bases, heavy metal salts and reducing agents.
Easy to hydrolyse when Sodium Diethylhexyl Sulfosuccinate encounters alkalis at high temperature.
CHEMICAL PROPERTIES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is an anionic surfactant that dissociates in aqueous solution to produce negatively charged sulfosuccinate ions.
Sodium Diethylhexyl Sulfosuccinate possesses two branched hydrophobic alkyl chains and a highly hydrophilic sulfonate group, resulting in exceptional surface activity and rapid adsorption at interfaces.
Sodium Diethylhexyl Sulfosuccinate's molecular structure enables extremely efficient reduction of surface and interfacial tension, allowing aqueous solutions to rapidly penetrate porous materials, powders, textiles, and solid surfaces.
This property makes Sodium Diethylhexyl Sulfosuccinate one of the most effective wetting agents available for industrial applications.
Sodium Diethylhexyl Sulfosuccinate exhibits excellent emulsifying and dispersing properties by stabilizing oil droplets and suspended particles through electrostatic repulsion.
Sodium Diethylhexyl Sulfosuccinate is chemically stable under recommended storage conditions and demonstrates good compatibility with many nonionic surfactants and formulation ingredients.
CHARACTERISTICS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is distinguished by its exceptionally fast wetting performance and outstanding ability to reduce surface tension even at very low concentrations.
Sodium Diethylhexyl Sulfosuccinate rapidly spreads aqueous solutions across hydrophobic and low-energy surfaces, improving contact between liquids and solid materials.
Sodium Diethylhexyl Sulfosuccinate demonstrates excellent penetration characteristics, allowing formulations to infiltrate porous substrates, powders, fibers, pigments, soils, and mineral surfaces quickly and uniformly.
This contributes to improved process efficiency and more consistent application performance.
Its balanced emulsifying and dispersing capabilities enable stable oil-in-water emulsions and homogeneous particle suspensions, making Sodium Diethylhexyl Sulfosuccinate suitable for complex industrial formulations requiring long-term physical stability.
Sodium Diethylhexyl Sulfosuccinate also exhibits excellent compatibility with numerous formulation additives and performs effectively over a broad concentration range, providing formulation flexibility across pharmaceutical, industrial, agricultural, and personal care applications.
PHYSICAL AND CHEMICAL PROPERTIES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
liquid at room temperature,
colourless to light yellow,
poorly dissolves in water,
Sodium Diethylhexyl Sulfosuccinate's density at 20ᵒC is 1.1 do 1.2 g/ml,
its viscosity at the same temperature is below 800 cP,
the cloud point for Diethylhexyl Sodium Sulfosuccinate is below 20ᵒC,
sensitive to pH variations.
TECHNICAL INFORMATION of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is considered one of the most efficient commercial wetting agents because of its remarkable ability to reduce the surface tension of water rapidly.
Sodium Diethylhexyl Sulfosuccinate's multifunctional performance as a wetting agent, dispersant, emulsifier, detergent, and penetration enhancer has led to widespread adoption across pharmaceutical manufacturing, industrial processing, agriculture, coatings, cosmetics, and specialty chemical production.
Its combination of excellent surface activity, low use levels, formulation versatility, and reliable processing performance has made Sodium Diethylhexyl Sulfosuccinate one of the most widely used sulfosuccinate surfactants in modern industrial chemistry.
STORAGE of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is stable in the solid state when stored at room temperature.
Dilute aqueous solutions of docusate sodium between pH 1–10 are stable at room temperature.
However, at very low pH (<1) and very high pH (>10) docusate sodium solutions are subject to hydrolysis.
Sodium Diethylhexyl Sulfosuccinate is hygroscopic and should be stored in an airtight container in a cool, dry place.
SOLUBILITY IN ORGANICS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is the dioctyl ester of sodium sulfosuccinate (bis-2-ethyl-hexyl sodium sulfosuccinate).
Sodium Diethylhexyl Sulfosuccinate dissolves slowly in water; at 25°C to the extent of 1.5 gm/100cc; at 70°C, 5.5 gm/100cc.
Sodium Diethylhexyl Sulfosuccinate dissolves in oils, hydrocarbons, fats and waxs by heating above 75°C and remains in solution when cooled to room temperature.
At room temperature, Sodium Diethylhexyl Sulfosuccinate is readily soluble in most organic solvents, both polar and non-polar.
Sodium Diethylhexyl Sulfosuccinate is soluble in carbon tetrachloride, petroleum ether, naphtha, xylene, dibutyl phthalate, liquid petroleum, acetone, alcohol, vegetable oils.
PURIFICATION METHODS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Dissolve Sodium Diethylhexyl Sulfosuccinate in MeOH and the inorganic salts which precipitate are filtered off.
Water is added and the solution is extracted several times with hexane.
The residue is evaporated to one-fifth its original volume, *benzene is added and azeotropic distillation is continued until no water remains.
The solvent is evaporated.
The white residual solid is crushed and dried in vacuo over P2O5 for 48hours.
Sodium Diethylhexyl Sulfosuccinate solubilises major myelin trans membrane proteolipids, and forms reverse micelles in hydrocarbon solvents.
PERFORMANCE of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Easy to dissolve in water, the solution is milky white, not resistant to strong acids, alkalis, heavy metal salts, and reducing agents.
Sodium Diethylhexyl Sulfosuccinate penetrates quickly and evenly, and has good wetting, penetration, emulsification, and foaming properties.
The penetration effect is best below 40 ℃, and Sodium Diethylhexyl Sulfosuccinate is more prone to hydrolysis when exposed to alkali at high temperatures.
Sodium Diethylhexyl Sulfosuccinate is suitable to treat the fabric with a penetrating agent before heating it up below 40 ℃.
Penetrant T is not resistant to strong alkalis and cannot be directly added to concentrated alkaline solution.
The alkaline solution should be diluted first before adding penetrant T.
PRODUCTION METHOD of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Dehydrated malic anhydride and 2-ethylhexanol undergo esterification reaction under the catalysis of p-toluenesulfonic acid, and the resulting esterification product is then sulfonated with sodium metabisulfite.
The sulfonated product is prepared by blending an appropriate amount of alcohol and distilled water to obtain the finished product.
The raw materials used are 2-ethylhexanol, secondary octanol or mixed alcohol, with a consumption of (kg/t) anhydrous malic anhydride (>98%) 107.6 secondary octanol (>80%) 298 sodium metabisulfite 145
Maleic anhydride and secondary octanol undergo esterification reaction under the catalysis of p-toluenesulfonic acid at 120-140 ℃.
The esterification product is mixed with sodium chloride sulfite and water, and heated evenly to 110-120 ℃ at a pressure of 0.2MPa.
The reaction is maintained until the endpoint (sample is added to water, and there is no yellow oily substance floating on the water surface as the endpoint).
The reaction is cooled to 80 ℃ and left to stand overnight.
The lower layer of water and a small amount of turbid sulfonate are discarded to obtain the finished product.
PRODUCTION METHODS of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Maleic anhydride is treated with 2-ethylhexanol to produce dioctyl maleate, which is then reacted with sodium bisulfite.
CHEMICAL PROPERTIES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Sodium Diethylhexyl Sulfosuccinate is a white solid, often supplied as an aqueous solution
Sodium Diethylhexyl Sulfosuccinate is a white or almost white, waxlike, bitter tasting, plastic solid with a characteristic octanol-like odor.
Sodium Diethylhexyl Sulfosuccinate is hygroscopic and usually available in the form of pellets, flakes, or rolls of tissuethin material.
PHYSICAL and CHEMICAL PROPERTIES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
Appearance: Colorless to pale yellow liquid, paste, or waxy solid
Physical State: Liquid or semi-solid (depending on grade)
Color: Colorless to light yellow
Odor: Mild characteristic odor
Molecular Formula: C₂₀H₃₇NaO₇S
Molecular Weight: 444.56 g/mol
CAS Number: 577-11-7
EC Number: 209-406-4
Ionic Character: Anionic
Density (25°C): Approximately 1.05–1.10 g/cm³
pH (1% solution): Approximately 5.0–7.5
Surface Tension Reduction: Excellent
Critical Micelle Concentration (CMC): Low
Wetting Speed: Very rapid
Water Solubility: Readily soluble
Solubility in Alcohols: Soluble
Solubility in Glycols: Soluble
Solubility in Hydrocarbons: Slightly soluble
Viscosity: Low to moderate (depending on formulation)
Flash Point: Typically >100°C
Boiling Point: Decomposes before boiling
Melting Point: Varies depending on commercial grade
Vapor Pressure: Very low
Volatility: Low
Foaming Characteristics: Moderate
Emulsifying Capacity: Excellent
Dispersing Efficiency: Excellent
Wetting Efficiency: Outstanding
Detergency: High
Thermal Stability: Good under normal processing conditions
Hydrolytic Stability: Good under neutral conditions
Electrolyte Compatibility: Good
Shelf Life: Typically 24 months under recommended storage conditions
Product Name: Sodium Diethylhexyl Sulfosuccinate
Chemical Name: Bis(2-ethylhexyl) Sodium Sulfosuccinate
IUPAC Name: Sodium bis(2-ethylhexyl) sulfosuccinate
Chemical Type: Anionic Surfactant
Chemical Family: Sulfosuccinate Ester
CAS No.: 577-11-7
EC No.: 209-406-4
Molecular Formula: C₂₀H₃₇NaO₇S
Molecular Weight: 444.56 g/mol
Physical Form: Colorless to Pale Yellow Liquid, Paste, or Waxy Solid (depending on grade and concentration)
Chemical Classification: Wetting Agent, Surface-Active Agent, Emulsifier, Dispersant
Molecular Weight: 360.40 g/mol
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 12
Exact Mass: 360.12186859 Da
Monoisotopic Mass: 360.12186859 Da
Topological Polar Surface Area: 129 Ų
Heavy Atom Count: 23
Formal Charge: 0
Complexity: 466
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Canonicalized: Yes
CBNumber: CB7769467
Molecular Formula: C20H37O7S.Na
Molecular Weight: 444.56
MDL Number: MFCD00012455
MOL File: 577-11-7.mol
Melting Point: 173-179 °C(lit.)
Boiling Point: 82.7°C
Density: 1.1
Vapor Pressure: 0Pa at 25℃
Storage Temp.: Inert atmosphere,Room Temperature
Solubility: methanol: 0.1 M at 20 °C, clear, colorless
Form: Waxy Solid
Specific Gravity: 1.005_PERCENT VOLATILE: 40
Color: White
Water Solubility: 1.5 g/100 mL (25 ºC)
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.05
Merck: 14,3401
BRN: 4117588
Henry's Law Constant: 2.0×106 mol/(m3Pa) at 25℃, HSDB (2015)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetic Ingredient Review (CIR): Dioctyl sulfosuccinate sodium salt (577-11-7)
InChI: 1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1
InChIKey: APSBXTVYXVQYAB-UHFFFAOYSA-M
SMILES: [Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S([O-])(=O)=O
LogP: 1.998 at 20℃
CAS DataBase Reference: 577-11-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS): DIOCTYL SODIUM SULFOSUCCINATE
FDA 21 CFR: 175.105; 175.300; 175.320;176.170; 176.180; 176.210;177.1200; 177.2800; 178.1010;178.3400
EWG's Food Scores: 1
FDA UNII: F05Q2T2JA0
ATC Code: A06AA02,A06AG10
EPA Substance Registry System: Bis(2-ethylhexyl) sodium sulfosuccinate (577-11-7)
UNSPSC Code: 41116107
NACRES: NA.25
FIRST AID MEASURES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of SODIUM DIETHYLHEXYL SULFOSUCCINATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
