SODIUM DODECYL SULFATE

SODIUM DODECYL SULFATE

CAS No. : 151-21-3
EC No. : 205-788-1

Synonyms:
Sodium monododecyl sulfate; Sodium lauryl sulfate; Sodium monolauryl sulfate; Sodium dodecanesulfate; Sodium coco-sulfate; dodecyl alcohol, hydrogen sulfate, sodium salt; n-dodecyl sulfate sodium; Sulfuric acid monododecyl ester sodium salt; SDS; Sodium laureth sulfate; Sodium myreth sulfate; Ammonium lauryl sulfate; Potassium lauryl sulfate; Sodyum dodesil sülfat; Sodium dodecyl sulfate; 151-21-3; SODIUM LAURYL SULFATE; Sodium dodecylsulfate; Sodium lauryl sulphate; Sodium dodecyl sulphate; Sodium dodecyl sulfate; SODIUM DODECYL SULFATE; Dodecyl sodium sulfate; Sodium dodecyl sulfate; SODIUM DODECYL SULPHATE; Anticerumen; Gardinol; Neutrazyme; Duponal; Irium; Stepanol methyl; Stepanol wac; Stepanol waq; Perlandrol L; Perlankrol L; Standapol wa-ac; Stepanol me dry; Dodecyl sulfate sodium salt; Sintapon L; Finasol osr2; Standapol WAQ; Stepanol WA; Incronol SLS; Maprobix NEU; Duponol QC; Duponol WA dry; Melanol CL; Dupanol WAQ; Duponol WAQE; Hexamol SLS; Dodecyl sulfate, sodium salt; Natriumlaurylsulfat; Sulfuric acid monododecyl ester sodium salt; Sipex SP; Sipex UB; Sodium n-dodecyl sulfate; Sterling WAQ-CH; Stepanol WA Paste; Avirol 118 conc; Duponol; Lauyl sodium sulfate; Stepanol T 28; Dreft; Aquarex methyl; Duponol methyl; Solsol needles; Steinapol NLS 90; Duponol waqa; Empicol LX 28; Melanol CL 30; NALS; Standapol waq special; Standapol was 100; Duponol qx; Jordanol SL-300; Richonol af; Stepanol WA-100; Finasol osr(sub 2); Standapol 112 conc; Stepanol ME Dry AW; Dodecyl sulfate sodium; Perklankrol ESD 60; Sipex sb; Sipex sd; Caswell No. 779; Duponol Me; Monagen Y 100; Richonol A; Richonol C; Duponol C; Maprofix LK; Stepanol ME; Akyposal SDS; Carsonol SLS; Maprofix NEU; Maprofix WAC; Stepanol methyl dry aw; Aquarex ME; Duponol WA; Duponol WAQ; Empicol LPZ; Natrium laurylsulfuricum; Berol 452; Duponal WAQE; Duponol WAQM; Lanette Wax-S; Sterling wa paste; Sodium dodecyl sulfate; Conco sulfate WA; Conco sulfate WN; EMAL O; Nikkol SLS; Orvus WA Paste; Sipex OP; Sipon LS; Sipon PD; Sipon WD; Detergent 66; Montopol La Paste; Sipon LS 100; Sipon LSB; Maprofix WAC-LA; Sodium monolauryl sulfate; Cycloryl 21; Sodyum dodesil sülfat; Cycloryl 31; Conco Sulfate WAG; Conco Sulfate WAN; Conco Sulfate WAS; Quolac EX-UB; Monododecyl sodium sulfate; Sodyum dodesil sülfat; Odoripon Al 95; Sodium monododecyl sulfate; Sodiumlauryl ether sulfate; Cycloryl 580; Cycloryl 585N; Lauryl sulfate sodium salt; Maprofix 563; Sinnopon LS 95; Laurylsiran sodny [Czech]; Empicol LS 30; Lauryl sodium sulfate; Rewopol NLS 30; Sinnopon LS 100; Carsonol SLS Special; SODIUM DODECYL SULPHATE; Dehydag sulfate GL emulsion; Lauryl sulfate, sodium salt; Avirol 101; Dehydrag sulfate gl emulsion; Dehydag sulphate GL emulsion; Emersal 6400; Monogen Y 100; Carsonol SLS Paste B; Emal 10; n-Dodecyl sulfate sodium; Conco sulfate WA-1200; Conco sulfate WA-1245; Product no. 75; Sodium lauryl sulfate ether; Sodium lauryl sulfate 30%; Product no. 161; MFCD00036175; Emulsifier no. 104; Sodium Laurylsulfate; CCRIS 6272; UNII-368GB5141J; HSDB 1315; P and G Emulsifier 104; NCI-C50191; Sodium lauryl sulfate, dental grade; Dodecyl alcohol, hydrogen sulfate, sodium salt; EINECS 205-788-1; EPA Pesticide Chemical Code 079011; NSC 402488; Sulfuric acid monododecyl ester sodium salt (1:1); SLS; CP 75424; Texapon K 1296; AI3-00356; CHEBI:8984; Laurylsulfuric Acid Sodium Salt; Dodecylsulfuric Acid Sodium Salt; 368GB5141J; NCGC00091020-03; DSSTox_CID_6031; DSSTox_RID_77989; DSSTox_GSID_26031; Sodium monododecyl sulfate; Sodium lauryl sulfate; Sodium monolauryl sulfate; Sodium dodecyl sulfate; SODIUM DODECYL SULFATE; Sodium dodecanesulfate; Sodium coco-sulfate; dodecyl alcohol, hydrogen sulfate, sodium salt; n-dodecyl sulfate sodium; Sulfuric acid monododecyl ester sodium salt; SDS; Sodium laureth sulfate; Sodium myreth sulfate; Ammonium lauryl sulfate; Potassium lauryl sulfate; Sodyum dodesil sülfat; Sodium dodecyl sulfate; 151-21-3; SODIUM LAURYL SULFATE; Sodium dodecylsulfate; Sodium lauryl sulphate; Sodium dodecyl sulphate; Dodecyl sodium sulfate; Sodium dodecyl sulfate; SODIUM DODECYL SULPHATE; Anticerumen; Gardinol; Neutrazyme dodecyl hydroxysulfonate, sodium salt; Sodium dodecyl sulfate; Laurylsiran sodny; Rhodapon UB; sodiumdodecylsulfate; CAS-151-21-3; Dodecyl sulfate, sodium salt, 85%, pure; Lauryl sulfate sodium; NSC-402488; Dodecyl sulfate, sodium salt, 99%, for biochemistry; Empicol; sodium lauryl; Sodyum dodesil sülfat; Sodium lauryl sulfate [JAN:NF]; Dodecyl sulfate, sodium salt, 99+%, for molecular biology, DNAse, RNAse and Protease free; Dodecyl sulfate, sodium salt, pure, granular, spec. acc. the requirements of Ph.Eur.; sodiumlauryl sulfate; Sodium laurilsulfate; Sodium Lauryl Sulfate [USAN:JAN]; sodium dodecylsulphate; odium dodecyl sulphate; Sodium dedecyl sulfate; Sodium-dodecyl-S-SDS; IPC-SDS; ACMC-1BXOT; sodium n-dodecyl sulphate; Sodium Lauryl Sulfate NF; lauryl sulphate sodium salt; EC 205-788-1; dodecyl sulphate sodium salt; SCHEMBL1102; C12H25NaO4S; sodium dodecyl sulfate (sds); KSC174S7B; n-Dodecyl sulfate sodium salt; ARONIS27060; CHEMBL23393; Sodium dodecyl sulfate, 99%; sodium dodecyl sulphate (sds); Sodium dodecyl sulfate; SODIUM DODECYL SULFATE; SODIUM DODECYL SULPHATE; Sodium dodecyl sulphate solution; DTXSID1026031; Sodium dodecyl sulfate; Sodyum dodesil sülfat; CTK0H4970; dodecyl sulfuric acid sodium salt; KS-00000VTL; Dodecyl sulphuric acid sodium salt; Sodyum dodesil sülfat; Sodium lauryl sulfate (JP17/NF); BCP30594; ANW-21329; LS-880; SBB060993; AKOS015897278; AKOS025147308; Tox21_111059_1; DB00815; Dodecyl sulfuric acid ester sodium salt; NE10918; KS-000048K2; Lauryl Sulfate, Sodium Salt (25% Aq.); D1403; FT-0603358; FT-0700721; I0352; Peg-(1-4)lauryl ether sulfate, sodium salt; Sodium dodecyl sulfate, 10% solution in water; SODIUM DODECYL SULFATE BIOTECH GRD 100G; Sodium dodecylsulfate;Sodium lauryl sulphate;Dodecyl sodium sulfate; Sodyum dodesil sülfat; Dodecyl sulfate, sodium salt, 98%, for biochemistry, suitable for electrophoresis; Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

SODIUM DODECYL SULFATE

Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is a synthetic organic compound with the formula CH3(CH2)11SO4Na. It is an anionic surfactant used in many cleaning and hygiene products. This molecule is an organosulfate and a salt. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of dodecyl hydrogen sulfate, the ester of dodecyl alcohol and sulfuric acid. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties and so make it useful as a detergent.[not verified in body] Also derived as a component of mixtures produced from inexpensive coconut and palm oils, Sodium dodecyl sulfate is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations.
Structure and properties
Structure of Sodium dodecyl sulfate
Sodium dodecyl sulfate is in the family of organosulfate compounds,[2] and has the formula, CH3(CH2)11SO4Na. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of a 12-carbon alcohol that has been esterified to sulfuric acid. An alternative description is that it is an alkyl group with a pendant, terminal sulfate group attached. As a result of its hydrocarbon tail, and its anionic "head group", it has amphiphilic properties that allow it to form micelles, and so act as a detergent.
Physicochemical properties
Bottle of 20% sodium dodecyl sulfate in distilled water for use in the laboratory.
The critical micelle concentration (CMC) in pure water at 25 °C is 8.2 mM,[1] and the aggregation number at this concentration is usually considered to be about 62.[3] The micelle ionization fraction (α) is around 0.3 (or 30%).

Production of Sodium dodecyl sulfate
Sodium dodecyl sulfate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.[5] The resulting product is then neutralized through the addition of sodium hydroxide or sodium carbonate.[citation needed] Lauryl alcohol can be used in pure form or may be derived from either coconut or palm kernel oil by hydrolysis (which liberates their fatty acids), followed by hydrogenation.[citation needed] When produced from these sources, commercial samples of these "Sodium dodecyl sulfate" products are actually not pure Sodium dodecyl sulfate, rather a mixture of various sodium alkyl sulfates with Sodium dodecyl sulfate being the main component.[6] For instance, Sodium dodecyl sulfate is a component, along with other chain-length amphiphiles, when produced from coconut oil, and is known as sodium coco sulfate (SCS).[7] Sodium dodecyl sulfate is available commercially in powder, pellet, and other forms (each differing in rates of dissolution), as well as in aqueous solutions of varying concentrations.
Applications of Sodium dodecyl sulfate
Cleaning and hygiene
Sodium dodecyl sulfate is mainly used in detergents for laundry with many cleaning applications.[8] It is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues; for example, it is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car exterior cleaners.
In lower concentrations, it is found in hand soap, toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.

Food additive of Sodium dodecyl sulfate
Sodium dodecyl sulfate, appearing as its synonym sodium lauryl sulfate (SLS), is considered a generally recognized as safe (GRAS) ingredient for food use according to the USFDA (21 CFR 172.822).[11] It is used as an emulsifying agent and whipping aid.[12] SLS is reported to temporarily diminish perception of sweetness.
Laboratory applications of Sodium dodecyl sulfate
Principal applications of Sodium dodecyl sulfate
Sodium lauryl sulfate, in science referred to as sodium dodecyl sulfate (Sodium dodecyl sulfate), is used in cleaning procedures,[14] and is commonly used as a component for lysing cells during RNA extraction and/or DNA extraction, and for denaturing proteins in preparation for electrophoresis in the Sodium dodecyl sulfate-PAGE technique.
Denaturation of a protein using Sodium dodecyl sulfate
In the case of Sodium dodecyl sulfate-PAGE, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e. causing the protein molecules to lose their native conformations and shapes. By binding to proteins at a ratio of one Sodium dodecyl sulfate molecule per 2 amino acid residues, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio.[16] In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their length as opposed to both their native charge and shape.[16][17] It is possible to make separation based on the size of the polypeptide chain to simplify the analysis of protein molecules, this can be achieved by denaturing proteins with the detergent Sodium dodecyl sulfate.[18] The association of Sodium dodecyl sulfate molecules with protein molecules imparts an associated negative charge to the molecular aggregate formed;[citation needed] this negative charge is significantly greater than the original charge of that protein.[citation needed] The electrostatic repulsion that is created by Sodium dodecyl sulfate binding forces proteins into a rod-like shape, thereby eliminating differences in shape as a factor for electrophoretic separation in gels.[citation needed] A dodecyl sulfate molecule has two negative charges at the pH value used for electrophoresis, this will lead the net charge of coated polypeptide chains to be much more negative than uncoated chains.[18] The charge-to-mass ratio is essentially identical for different proteins because Sodium dodecyl sulfate coating dominates the charge.

Miscellaneous applications of Sodium dodecyl sulfate
Sodium dodecyl sulfate is used in an improved technique for preparing brain tissues for study by optical microscopy. The technique, which has been branded as CLARITY, was the work of Karl Deisseroth and coworkers at Stanford University, and involves infusion of the organ with an acrylamide solution to bind the macromolecules of the organ (proteins, nucleic acids, etc.), followed by thermal polymerization to form a "brain–hydrogel" (a mesh interspersed throughout the tissue to fix the macromolecules and other structures in space), and then by lipid removal using Sodium dodecyl sulfate to eliminate light scattering with minimal protein loss, rendering the tissue quasi-transparent.[19][20]
Along with sodium dodecylbenzene sulfonate and Triton X-100, aqueous solutions of Sodium dodecyl sulfate are popular for dispersing or suspending nanotubes, such as carbon nanotubes.

Niche uses of Sodium dodecyl sulfate
Sodium dodecyl sulfate has been proposed as a potentially effective topical microbicide, for intravaginal use, to inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the herpes simplex viruses, HIV, and the Semliki Forest virus.[22][23]
In gas hydrate formation experiments, Sodium dodecyl sulfate is used as a gas hydrate growth promoter.[24][25] [26] Researchers aim for gas hydrate promotions as scale-up of industrial applications of gas hydrates such as desalination process,[27] gas storage, and gas separation technologies.[28]
Liquid membranes formed from Sodium dodecyl sulfate in water have been demonstrated to work as unusual particle separators.[29] The device acts as a reverse filter, allowing large particles to pass while capturing smaller particles.

Toxicology of Sodium dodecyl sulfate
Carcinogenicity
Sodium dodecyl sulfate is not carcinogenic when consumed or applied directly, even to amounts and concentrations that exceed amounts used in standard commercial products.[30][31] The earlier review of the Cosmetic Ingredient Review (CIR) program Expert Panel in 1983 reported that Sodium dodecyl sulfate (there, abbreviated SLS, for sodium lauryl sulfate) in concentrations up to 2%, in a year-long oral dietary studies in dogs, gave no evidence of tumorigenicity or carcinogenicity, and that no excess chromosomal aberrations or clastogenic effects were observed in rats fed up to 1.13% sodium lauryl sulfate in their diets for 90 days, over those on a control diet.[30]:157, 175 The 2005 review by the same group indicated that further available data lacked any available suggestion that Sodium dodecyl sulfate or the related ammonium salt of the same amphiphile could be carcinogenic, stating that "Despite assertions to the contrary on the Internet, the carcinogenicity of these ingredients is only a rumor;" both studies conclude that Sodium dodecyl sulfate appears "to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%.

Sensitivity of Sodium dodecyl sulfate
Like all detergents, sodium lauryl sulfate removes oils from the skin, and can cause skin and eye irritation.[citation needed] It has been shown to irritate the skin of the face, with prolonged and constant exposure (more than an hour) in young adults.[32] Sodium dodecyl sulfate may worsen skin problems in individuals with chronic skin hypersensitivity, with some people being affected more than others.[33][34][35]
Oral concerns of Sodium dodecyl sulfate
The low cost of Sodium dodecyl sulfate,[36] its lack of impact on taste,[36] its potential impact on volatile sulfur compounds (VSCs), which contribute to malodorous breath,[37] and its desirable action as a foaming agent have led to the use of Sodium dodecyl sulfate in the formulations of toothpastes.[36] A series of small crossover studies (25-34 patients) have supported the efficacy of SLS in the reduction of VSCs, and its related positive impact on breath malodor, although these studies have been generally noted to reflect technical challenges in the control of study design variables.[37] While primary sources from the group of Irma Rantanen at University of Turku, Finland conclude an impact on dry mouth (xerostomia) from SLS-containing pastes, a 2011 Cochrane review of these studies, and of the more general area, concludes that there "is no strong evidence… that any topical therapy is effective for relieving the symptom of dry mouth."[38] A safety concern has been raised on the basis of several studies regarding the effect of toothpaste Sodium dodecyl sulfate on aphthous ulcers, commonly referred to as canker or white sores.[36] A consensus regarding practice (or change in practice) has not appeared as a result of the studies.[39][40] As Lippert notes, of 2013, "very few… marketed toothpastes contain a surfactant other than SLS [Sodium dodecyl sulfate]," and leading manufacturers continue to formulate their produce with Sodium dodecyl sulfate.
Interaction with fluoride
Some studies have suggested that SLS in toothpaste may decrease the effectiveness of fluoride at preventing dental caries (cavities). This may be due to SLS interacting with the deposition of fluoride on tooth enamel.

Readily pourable, palm-derived, high foaming, anionic surfactant used in the chemical formulating and detergent manufacturing industries. It is a higher foaming variation of Sodium Lauryl Sulfate (SLES).
Features of Sodium dodecyl sulfate :
Free flowing liquid makes it easier to pour.
Used in wetting agent formulations, liquid detergents, cleaners, shampoos and laundry detergents.
Sodium dodecyl sulfate dissolves readily in hard and soft water and provides a consistent foam character.
Packaging of Sodium dodecyl sulfate :
Sodium dodecyl sulfate is available in IBCs (1000kg bulk containers) and drums.
Safety of Sodium dodecyl sulfate :
Please consult the SDS on Sodium dodecyl sulfate before use.
Sodium dodecyl sulfate (sodium dodecyl sulphate) is a kind of anionic surfactant, dissolves in the water easily, compatibility with anion and non-ionic, good performances on emulsifying, foaming, osmosis, detergency and de-centrality. Sodium dodecyl sulfate Powder Sodium dodecyl sulfate Powder is a widely used surfactant often used as a foaming agent in many common products like Bath products, shampoos, foaming powders and mony industrial and commercial cleaners. SaveonCitric offers a highly Active, high quality Sodium dodecyl sulfate Powdered Sodium dodecyl sulfate. If you are formulating a product like a powdered or tablet cleanser, or blending liquid hard surface or carpet cleaners, try Sodium dodecyl sulfate Powder. Check the FIFRa list if you are formulating blends and looking for an accepted surfactant. Sodium dodecyl sulfate , synonymously, Sodium dodecyl sulfate , or sodium laurilsulfate, is a synthetic organic compound with the formula CH3(CH2)11SO4Na. It is an anionic surfactant used in many cleaning and hygiene products. The sodium salt is of an organosulfate class of organics. It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of dodecyl hydrogen sulfate, the ester of dodecyl alcohol and sulfuric acid. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties and so make it useful as a detergent.[not verified in body] Also derived as a component of mixtures produced from inexpensive coconut and palm oils, Sodium dodecyl sulfate is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations. Sodium dodecyl sulfate is a widely used surfactant in cleaning products, cosmetic, and personal care products. Sodium dodecyl sulfate 's uses in these products have been thoroughly evaluated and determined to be safe for consumers and the environment. Sodium dodecyl sulfate , sodium laurilsulfate or sodium dodecyl sulfate (Sodium dodecyl sulfate or NaDS) (C12H25SO4Na) is an anionic surfactant used as an emulsifying cleaning agent in many cleaning and hygiene products. Sodium dodecyl sulfate is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues. For example, it is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps. It is used in lower concentrations with toothpastes, shampoos, and shaving foams. It is an important component in bubble bath formulations for its thickening effect and its ability to create a lather.

WHAT IS Sodium dodecyl sulfate ?
Sodium dodecyl sulfate , also known as Sodium dodecyl sulfate, is a widely used surfactant in cleaning products, cosmetics, and personal care products. The Sodium dodecyl sulfate formula is a highly effective anionic surfactant used to remove oily stains and residues. It is found in high concentrations in industrial products, including engine degreasers, floor cleaners, and car wash products, where workplace protections can be implemented to avoid unsafe exposures. Sodium dodecyl sulfate is also used in lower concentrations in household and personal care products such as cleaning products, toothpastes, shampoos, and shaving foams.
SAFETY
Sodium dodecyl sulfate has been thoroughly reviewed for its safety by a number of governments. For example:
Based on a thorough safety review, including consideration of chronic risks, the U.S. Environmental Protection Agency (EPA) has issued an exemption for 
Sodium dodecyl sulfate from the requirement of tolerance for residues when used as a component of food contact sanitizing solutions applied to all food contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils at a maximum level in the end-use concentration of 350 parts per million (ppm). The regulation eliminates the need to establish a maximum permissible level for residues of Sodium dodecyl sulfate. The Food and Drug Administration (FDA) includes Sodium dodecyl sulfate on its list of multipurpose additives allowed to be directly added to food. Sodium dodecyl sulfate and Ammonium Lauryl Sulfate are also approved indirect food additives. For example, both ingredients are permitted to be used as components of coatings. Sodium dodecyl sulfate and Ammonium Lauryl Sulfate may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Directive of the European Union. The Organization of Economic Cooperation and Development, which is an organization of 30-plus developed countries, has reviewed the human and environmental hazards of a category of chemicals that includes Sodium dodecyl sulfate. No chronic human health hazards, including carcinogenicity, were identified. The hazard assessment for the category (alkyl sulphates, alkane sulphonates and alpha-olefin sulphonates category) is posted on the OECD website.
Sodium dodecyl sulfate has also been thoroughly reviewed for human safety by an industry funded, independent panel, which found: There is no evidence of harm from the use of Sodium dodecyl sulfate in cosmetic products, where there is intentional, direct contact with the skin. The ingredient was reviewed in 1983 and re-reviewed in 2005 by the Cosmetic Ingredient Review (CIR)1 Expert Panel and found to be safe for use in cosmetic and personal care products. Sodium dodecyl sulfate can cause skin irritation in some persons, which is one reason why it is important to follow the label instructions when using a cleaning product. A complete report on Sodium dodecyl sulfate is available from CIR.

Use:
-Detergency: tooth paste, shampoo, cosmetic, detergent, etc.
-Construction: plasterboard, additive of concrete, coating, etc.
-Pharmaceutical: Medicine, pesticide, etc.
-Leather: leather soft agent, wool cleaning agent, etc.
-Paper making: penetrant, flocculating agent, deinking agent, etc.
-Auxiliaries: textile auxiliaries, plastic auxiliaries, etc.
-Fire fighting: oil well fire fighting, fire fighting device, etc.
-Mineral choosing: mine flotation, coal water mixture, etc.
Overview
Sodium dodecyl sulfate is one of the ingredients you'll find listed on your shampoo bottle. However, unless you're a chemist, you likely don't know what it is. The chemical is found in many cleaning and beauty products, but it's frequently misunderstood.
Urban myths have linked it to cancer, skin irritation, and more. Science may tell a different story.
How it works
Sodium dodecyl sulfate is what's known as a "surfactant." This means it lowers the surface tension between ingredients, which is why it's used as a cleansing and foaming agent.
Most concerns about Sodium dodecyl sulfate stem from the fact that it can be found in beauty and self-care products as well as in household cleaners.
Sodium dodecyl sulfate is a surfactant with a similar chemical formula. However, SLES is milder and less irritating than Sodium dodecyl sulfate.
Where you'll find Sodium dodecyl sulfate 
If you look under your bathroom sink, or on the shelf in your shower, it's very likely you'll find Sodium dodecyl sulfate in your home. It's used in a variety of products, including:
Grooming products, such as shaving cream, lip balm, hand sanitizer, nail treatments, makeup remover, foundation, facial cleansers, exfoliants, and liquid hand soap
Hair products, such as shampoo, conditioner, hair dye, dandruff treatment, and styling gel
Dental care products, such as toothpaste, teeth whitening products, and mouthwash
Bath products, such as bath oils or salts, body wash, and bubble bath
Creams and lotions, such as hand cream, masks, anti-itch creams, hair-removal products, and sunscreen
You'll notice that all of these products are topical, or applied directly to the skin or body.
Sodium dodecyl sulfate is also used as a food additive, usually as an emulsifier or a thickener. It can be found in dried egg products, some marshmallow products, and certain dry beverage bases.
Are there dangers?
The Food and Drug Administration (FDA) regards Sodium dodecyl sulfate as safe as a food additive.
Regarding its use in cosmetics and body products, the safety assessment study of Sodium dodecyl sulfate , published in 1983 in the International Journal of Toxicology (the most recent assessment), found that it's not harmful if used briefly and rinsed from the skin, as with shampoos and soaps.
The report says that products that stay on the skin longer shouldn't exceed 1 percent concentration of Sodium dodecyl sulfate.
However, the same assessment did suggest some possible, albeit minimal, risk to humans using Sodium dodecyl sulfate. For example, some tests found that continuous skin exposure to Sodium dodecyl sulfate could cause mild to moderate irritation in animals.
Nevertheless, the assessment concluded that Sodium dodecyl sulfate is safe in formulations used in cosmetics and personal care products. Because many of these products are designed to be rinsed off after short applications, the risks are minimal.
According to most research, Sodium dodecyl sulfate is an irritant but not a carcinogen. Studies have shown no link between the use of Sodium dodecyl sulfate and increased cancer risk.
According to a 2015 study, Sodium dodecyl sulfate is safe for use in household cleaning products.

About 1/3 of HIV positive mothers transmit the virus to their newborns, and 1/2 of these infections occur during breastfeeding. Sodium dodecyl sulfate (SDS), an anionic surfactant, is a common ingredient of cosmetic and personal care products. Sodium dodecyl sulfate is "readily biodegradable" with low toxicity and "is of no concern with respect to human health". Up to 1 g of Sodium dodecyl sulfate/kg is the maximum safe dose for children. Alkyl sulfates, including Sodium dodecyl sulfate, are microbicidal against HIV types 1 and 2, herpes simplex virus type 2 (HSV-2), human papillomaviruses and chlamydia. /The study/ hypothesizes that Sodium dodecyl sulfate treatment of milk will inactivate HIV-1 without significant harm to its nutritional value and protective functions and may define a treatment of choice for breastwas at 37 degrees C for 10 min. Sodium dodecyl sulfate-PAGE and Lowry were used to analyze protein content. Antibody content and function was studied by rocket immunoelectrophoresis (RIE), immunoturbodimentric (ITM) quantitation and ELISA. The creamatocrit was also analyzed. HIV-1 infectivity was measured by MAGI assay. Sodium dodecyl sulfate removal was by Detergent-OutN (Geno Technology, Inc.). Sodium dodecyl sulfate quantitation is by methylene blue-chloroform method. Inactivation of HIV-1 with Sodium dodecyl sulfate occurs at or above 0.025%. In milk samples, 1% and 0.1% Sodium dodecyl sulfate reduced HSV-2 infectivity. At least 90% of Sodium dodecyl sulfate can be efficiently removed with Detergent-OutN, with protein recovery of 80%-100%. Gross protein species are conserved as indicated by PAGE analyses. Fat and energy content of Sodium dodecyl sulfate-treated breast milk remains unchanged. 0.1% Sodium dodecyl sulfate can be removed from human milk without altering the creamatocrit. ELISA of serum IgG (rubella) proved it remains functional in the presence of Sodium dodecyl sulfate and after its removal. sIgA, IgG and IgM in breast milk are conserved after Sodium dodecyl sulfate-treatment when measured by RIE and ITM. CONCLUSIONS: Sodium dodecyl sulfate (0.025%) can inactivate HIV-1 in vitro and HSV-2 in breast milk. Sodium dodecyl sulfate can be efficiently removed from milk samples. Sodium dodecyl sulfate treatment of milk does not significantly alter protein content. Antibody function in serum and levels in breast milk are maintained after treatment and removal of Sodium dodecyl sulfate. 0.1% Sodium dodecyl sulfate does not alter fat concentration in milk and energy content is conserved. Sodium dodecyl sulfate or related compounds may be used to prevent breast milk transmission of HIV-1.

A broad-spectrum vaginal microbicide must be effective against a variety of sexually transmitted disease pathogens and be minimally toxic to the cell types found within the vaginal epithelium, including vaginal keratinocytes. /The study/ assessed the sensitivity of primary human vaginal keratinocytes to potential topical vaginal microbicides nonoxynol-9 (N-9), C31G, and sodium dodecyl sulfate (SDS). Direct immunofluorescence and fluorescence-activated cell sorting analyses demonstrated that primary vaginal keratinocytes expressed epithelial cell-specific keratin proteins. Experiments that compared vaginal keratinocyte sensitivity to each agent during a continuous, 48-hr exposure demonstrated that primary vaginal keratinocytes were almost five times more sensitive to N-9 than to either C31G or Sodium dodecyl sulfate. To evaluate the effect of multiple microbicide exposures on cell viability, primary vaginal keratinocytes were exposed to N-9, C31G, or Sodium dodecyl sulfate three times during a 78-hr period. In these experiments, cells were considerably more sensitive to C31G than to N-9 or Sodium dodecyl sulfate at lower concentrations within the range tested. When agent concentrations were chosen to result in an endpoint of 25% viability after three daily exposures, each exposure decreased cell viability at the same constant rate. When time-dependent sensitivity during a continuous 48-hr exposure was examined, exposure to C31G for 18 hr resulted in losses in cell viability not caused by either N-9 or Sodium dodecyl sulfate until at least 24 to 48 hr. Cumulatively, these results reveal important variations in time- and concentration-dependent sensitivity to N-9, C31G, or Sodium dodecyl sulfate within populations of primary human vaginal keratinocytes cultured in vitro. These investigations represent initial steps toward both in vitro modeling of the vaginal microenvironment and studies of factors that impact the in vivo efficacy of vaginal topical microbicides.

Sodium dodecyl sulfate (SDS) is an anionic detergent that can form complexes with protein through hydrophobic interactions. Studies have reported that the hydrodynamic functions of protein-Sodium dodecyl sulfate complexes are governed by the length of their polypeptide chains. Thus, Sodium dodecyl sulfate-based electrophoretic techniques can separate protein molecules based on their molecular weights. Additionally, Sodium dodecyl sulfate can solubilize cell membranes and can extract membrane-bound proteins.
Analytical procedures are described for determining residues of sodium dodecyl sulfate in whole blood from guinea pigs. Methods are based on hydrolysis & analysis by electron-capture gas-chromatography.

Sodium Dodecyl Sulfate Electrophoresis
Sodium dodecyl sulfate electrophoresis was the next logical step after disk electrophoresis. While the latter discriminates macromolecules on the basis of both size and surface charge, Sodium dodecyl sulfate electrophoresis fractionates polypeptide chains essentially on the basis of their size. It is therefore a simple, yet powerful and reliable method for molecular mass (Mr) determination. In 1967, it was first reported that electrophoretic migration in Sodium dodecyl sulfate is proportional to the effective molecular radius and thus to the Mr of the polypeptide chain. This result means that Sodium dodecyl sulfate must bind to proteins and cancel out differences in molecular charge, so that all components then migrate solely according to size. Surprisingly large amounts of Sodium dodecyl sulfate appear to be bound (an average of 1.4 g Sodium dodecyl sulfate per gram of protein), which means that the number of Sodium dodecyl sulfate molecules bound is of the order of half the number of amino acid residues in a polypeptide chain. This amount of highly charged surfactant molecules is sufficient to overwhelm effectively the intrinsic charges of the polymer coil, so that their net charge per unit mass becomes approximately constant. If migration in Sodium dodecyl sulfate (and disulfide reducing agents, such as 2-mercaptoethanol, in the denaturing step, for a proper unfolding of the proteins) is proportional only to molecular mass, then, in addition to canceling out of charge differences, Sodium dodecyl sulfate also equalizes molecular shape differences as well (e.g., globular versus rod-shaped molecules). This seems to be the case for protein–Sodium dodecyl sulfate mixed micelles: these complexes can be assumed to behave as ellipsoids of constant minor axis (∼1.8 nm) and with the major axis proportional to the length in amino acids (i.e., to molecular mass) of the protein. The rod length for the 1.4 g Sodium dodecyl sulfate/g protein complex is of the order of 0.074 nm per amino acid residue.

Sodium dodecyl sulfate
Sodium dodecyl sulfate (SDS), also known as lauryl sulfate, is an ionic detergent that is useful for the rapid disruption of biological membranes. It is a key component of many reagents used to purify nucleic acids because of its abilities to quickly disrupt the tissue architecture and to inhibit both RNase and deoxyribonuclease (DNase) activity. Sodium dodecyl sulfate is usually prepared as either a 10% or a 20% (w/v) stock solution and is used most often at a working concentration of 0.1% to 0.5%. The performance of this detergent can be affected significantly by its purity. Sodium dodecyl sulfate is easily precipitable in the presence of potassium salts and generally is not added to guanidinium buffers, as it has very low solubility in high-salt, chaotropic solutions.
Two classes of proteins show anomalous behavior in Sodium dodecyl sulfate electrophoresis: glycoproteins (because their hydrophilic oligosaccharide units prevent hydrophobic binding of Sodium dodecyl sulfate micelles) and strongly basic proteins (e.g., histones) (because of electrostatic binding of Sodium dodecyl sulfate micelles through their sulfate groups). The first can be partially alleviated by using Tris–borate buffers at alkaline pH, which will increase the net negative charge on the glycoprotein, thus producing migration rates well correlated with molecular size. Migration of histones can be improved by using pore gradient gels and allowing the polypeptide chains to approach the pore limit.