PRODUCTS

SODIUM DODECYL SULFATE

Sodium dodecyl sulfate has a role as a detergent and a protein denaturant.
Sodium dodecyl sulfate is a major component of detergent.
Sodium dodecyl sulfate is usually used in the DNA extraction process to separate DNA after protein denaturation.

CAS Number: 151-21-3
E number: E487 (thickeners, ...)
Molecular Formula: NaSO4C12H25 / C12H25O4S.Na / C12H25NaO4S
Molar mass: 288.372 g/mol

SYNONYMS:
Sodium dodecyl sulfate, Sodium monododecyl sulfate, Sodium lauryl sulfate, Sodium monolauryl sulfate, Sodium dodecanesulfate, dodecyl alcohol, hydrogen sulfate, sodium salt, n-dodecyl sulfate sodium, Sulfuric acid monododecyl ester sodium salt, Sodium dodecyl sulfate, 151-21-3, SODIUM LAURYL SULFATE, Sodium dodecylsulfate, Sodium lauryl sulphate, Sodium dodecyl sulphate, Sodium n-dodecyl sulfate, Dodecyl sodium sulfate, Anticerumen, Duponal, Gardinol, Stepanol methyl, Neutrazyme, Stepanol wac, Stepanol waq, Perlandrol L, Perlankrol L, Stepanol me dry, Sintapon L, Finasol osr2, Standapol WAQ, Stepanol WA, Duponol QC, Incronol SLS, Maprobix NEU, Melanol CL, Dupanol WAQ, Duponol WA dry, Hexamol SLS, Duponol WAQE, Natriumlaurylsulfat, Sipex SP, Sipex UB, Sterling WAQ-CH, Stepanol WA Paste, Dodecyl sulfate, sodium salt, Avirol 118 conc, Duponol, Dreft, Irium, Lauyl sodium sulfate, Stepanol T 28, Sulfuric acid monododecyl ester sodium salt, Aquarex methyl, Duponol methyl, Empicol LX 28, Melanol CL 30, NALS, Sodium monododecyl sulfate, Solsol needles, Steinapol NLS 90, Duponol waqa, Lauryl sulfate sodium salt, Richonol af, Standapol waq special, Standapol was 100, Duponol qx, Finasol osr(sub 2), Perklankrol ESD 60, sodium, dodecyl sulfate, Standapol 112 conc, Stepanol ME Dry AW, Dodecyl sulfate sodium, Duponol Me, Monagen Y 100, Richonol A, Richonol C, Sipex sb, Sipex sd, Duponol C, Maprofix LK, Stepanol ME, Akyposal SDS, Aquarex ME, Carsonol SLS, Duponol WA, Maprofix NEU, Maprofix WAC, Stepanol methyl dry aw, Berol 452, Duponol WAQ, Empicol LPZ, Natrium laurylsulfuricum, Conco sulfate WA, Conco sulfate WN, Duponal WAQE, Duponol WAQM, EMAL O, Orvus WA Paste, Sterling wa paste, Nikkol SLS, Detergent 66, Sipex OP, Sipon LS, Sipon LS 100, Sipon PD, Sipon WD, Maprofix WAC-LA, Montopol La Paste, Sipon LSB, Cycloryl 21, Cycloryl 31, Sodium monolauryl sulfate, Conco Sulfate WAG, Conco Sulfate WAN, Conco Sulfate WAS, Quolac EX-UB, Sodium laurilsulfate, Monododecyl sodium sulfate, Odoripon Al 95, Sodiumlauryl ether sulfate, Cycloryl 580, Cycloryl 585N, Maprofix 563, Sinnopon LS 95, Empicol LS 30, Rewopol NLS 30, Lauryl sodium sulfate, Sinnopon LS 100, Carsonol SLS Special, Dehydag sulfate GL emulsion, Lauryl sulfate, sodium salt, Avirol 101, Dehydrag sulfate gl emulsion, Monogen Y 100, Dehydag sulphate GL emulsion, Emersal 6400, Carsonol SLS Paste B, Emal 10, Laurylsiran sodny, n-Dodecyl sulfate sodium, Conco sulfate WA-1200, Conco sulfate WA-1245, Sodium lauryl sulfate 30%, Texapon k 12 p, Emulsifier no. 104, P and G Emulsifier 104, NCI-C50191, Sodium lauryl sulfate, dental grade, Dodecyl alcohol, hydrogen sulfate, sodium salt, CP 75424, DTXSID1026031, Trepenol WA, sodium monododecyl sulphate, Tarapon K 12, 368GB5141J, NSC-402488, CHEBI:8984, DTXCID906031, Sensible, Bamboo Salt 160g, Sodium lauryl sulfate, Lauryl Sulfate, Sodium, Sulfate, Sodium Lauryl, Dodecyl Sulfate, Sodium, Sulfate, Sodium Dodecyl, RefChem:887658, Monosodium monododecyl sulfate, 205-788-1, Standapol wa-ac, Stepanol WA-100, MFCD00036175, Sodium lauryl sulfate ether, Sodium Laurylsulfate, SLS, C12H25NaO4S, Sodium lauryl sulfate, synthetic, NCGC00091020-03, Jordanol SL-300, Caswell No. 779, sodiumdodecylsulfate, 12738-53-3, 12765-21-8, 1334-67-4, Laurylsiran sodny [Czech], Laurylsulfuric Acid Sodium Salt, Dodecylsulfuric Acid Sodium Salt, dodecyl hydroxysulfonate, sodium salt, Sodium dodecyl sulfate for Electrophoresis, inverted exclamation markY98.5%, CAS-151-21-3, CCRIS 6272, HSDB 1315, E487, EINECS 205-788-1, EPA Pesticide Chemical Code 079011, NSC 402488, Empicol, AI3-00356, Sodium Laurylsulfate, Sodium laurilsulfate, Sodium dodecyl sulfate, UNII-368GB5141J, Sodium lauryl sulfate [JAN:NF], sodiumlauryl sulfate, sodium dodecylsulphate, Sodium dedecyl sulfate, IPC-SDS, Lauryl sulfatesodium salt, Sodium laurilsulfate CRS, Sodium dodecyl sulfateSDS, Sodium Lauryl Sulfate NF, SDS (20% Solution), EC 205-788-1, SCHEMBL1102, Sodium lauryl sulfate, SDS, Sodium dodecyl sulfate(SDS), Sodium dodecyl sulfate(K12), Sulfuric acid monododecyl ester sodium salt (1:1), CHEMBL23393, orb1705834, HY-Y0316B, HMS5085M10, Sodium dodecyl sulfate, crystalline, Sodium lauryl sulfate (JP17/NF), SODIUM LAURYL SULFATE [II], SODIUM LAURYL SULFATE [MI], CS-B1770, HY-Y0316, SODIUM LAURYL SULFATE [FCC], SODIUM LAURYL SULFATE [JAN], Tox21_111059, Tox21_201614, Tox21_300149, EBC-03742, SBB060993, SODIUM LAURILSULFATE [MART.], SODIUM LAURYL SULFATE [HSDB], SODIUM LAURYL SULFATE [VANDF], AKOS015897278, AKOS025147308, Tox21_111059_1, DB00815, FS15952, FS59780, MSK002093-100W, SODIUM LAURYL SULFATE [USP-RS], SODIUM LAURYL SULFATE [WHO-DD], NCGC00091020-01, NCGC00091020-02, NCGC00254225-01, NCGC00259163-01, NCGC00274082-01, AS-14730, Sodium dodecyl sulfate, ACS reagent grade, SODIUM LAURILSULFATE [EP IMPURITY], SODIUM LAURILSULFATE [EP MONOGRAPH], DB-188912, CS-0182093, D1403, I0352, NS00077200, S0588, ST51037318, D01045, EN300-103513, F16341, M02544, SDS, Sodium laurylsulfate, Sodium lauryl sulphate, Q422241, Lauryl Sulfate Sodium Salt (Sodium Lauryl Sulfate), Sodium dodecyl sulfate Solution in Water, 100ug/mL, Sodium n-dodecyl sulfate, 98%, for electrophoresis, F0001-0539, Sodium Lauryl Sulphate 0.02N (naturally short expiry), Z1365432828, Dissolution Media Sodium Lauryl Sulphate 0.50% (Concentrate)(12x400mls), Dissolution Media - Ready to Use (acc. USP) - Sodium Lauryl Sulphate 0.50%, Dissolution Media Sodium Lauryl Sulphate 0.50% - 500ml of conc. dilutes to 10L, Analytical Volumetric Solution Sodium Lauryl (Dodecyl) Sulphate 0.1M (0.1N)-Naturally short expiry, Dissolution Media Concentrate Sodium Lauryl Sulphate 0.50% - 1000ml of conc. dilutes to 20L, Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate, Reagecon Sodium Dodecyl Sulphate 0.1% w/v in 0.1M Hydrochloric Acid Dissolution Media in accordance to United States (USP) and European Pharmacopoeias (EP), Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate, Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate, Sodium dodecyl sulfate, Sodium n-Dodecyl Sulfate, Sodium n-Dodecyl Sulfate, Molecular Biology Grade, Dodecyl hydrogen sulfate sodium salt, Sodium n-Dodecyl Sulfate, High Purity, SDS, SLES, SODIUM LAURYL SULFATE, sls, SODIUM LAURYL SULPHATE, SODIUM DODECYL SULPHATE, LAURYL SODIUM SULFATE, Rutile Sand, DODECYL SULFATE SODIUM SALT, LAURYL SULFATE SODIUM SALT

Sodium dodecyl sulfate is a white to pale yellow paste or liquid with a mild odor.
Sodium dodecyl sulfate sinks and mixes with water.
Sodium dodecyl sulfate is insoluble in water.

Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate with CAS number 151-21-3, is an anionic surfactant extensively used in biochemical research.
Sodium dodecyl sulfate's primary function involves disrupting non-covalent bonds within proteins, leading to their denaturation, a process integral to SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis) techniques.

In SDS-PAGE, Sodium dodecyl sulfate binds uniformly to proteins, imparting a negative charge proportional to their molecular weight, thereby enabling their separation based on size under an electric field.
This action is due to Sodium dodecyl sulfate’s ability to penetrate hydrophobic regions of proteins, unfolding their complex structures into linear forms.

Additionally, Sodium dodecyl sulfate is crucial in nucleic acid extraction, where it facilitates cell lysis and denatures proteins to release DNA and RNA.
Beyond laboratory settings, Sodium dodecyl sulfate’s properties as a surfactant find usage in industrial applications, particularly in detergents, due to its efficacy in solubilizing fats and oils.

Sodium dodecyl sulfate's role in research extends to studying micelle formation and protein-protein interactions, underlining its versatility and importance in scientific studies that require precise manipulation and analysis of biomolecules.
Sodium dodecyl sulfate is an anionic surfactant commonly used as a detergent, emulsifier, and protein denaturant in various industrial processes, especially in the production of personal care products, cleaners, and laboratory reagents.

Sodium dodecyl sulfate has unique chemical properties that make it an effective ingredient in many applications, helping to reduce surface tension and enhance cleaning power.
Sodium Dodecyl Sulfate, also known as Sodium Lauryl Sulfate or SDS, is an ionic detergent used to denature native proteins for gel electrophoresis.

The most common sulphate surfactant is Sodium dodecyl sulfate probably most extensively studied anionic surfactant known to science.
Sodium dodecyl sulfate is sometimes referred to as sodium laurylsulphate (SLS).
Sodium dodecyl sulfate is an organic compound commercially found in the form of Powder or Pellet.

Sodium dodecyl sulfate is found that pellet form is more soluble in water and less toxic than the powder form.
Like all detergents Sodium dodecyl sulfate removes oils from the skin and can cause skin and eye irritation in higher concentration.
If the concentration is less than 1%, Sodium dodecyl sulfate's such carcinogenic character decreases.

Sodium dodecyl sulfate's cmc in pure water at 250C is 0.0082M and the aggregation number at this concentration is usually considered to be about 62.
If any electrolyte is added to a solution of Sodium dodecyl sulfate or temperature or pressure changes, the aggregation behavior of SDS affected.

For example, when chloride, acetate and propionate co-ions are added to the aqueous solution of Sodium dodecyl sulfate, then the value of cmc affected.
Acetate, propionate and butyrate do not have any effect on the cmc of Sodium dodecyl sulfate.

Butyrate ion, however, shows influence on the adsorption behaviour and aggregation number of Sodium dodecyl sulfate.
Thus, co-ion with up to four carbon atoms does not affect the cmc of Sodium dodecyl sulfate.
Further investigation is required to ascertain the minimum number of carbon atoms required in the co-ion for showing the influence on cmc of Sodium dodecyl sulfate.

Sodium dodecyl sulfate is most researched and best understood widely used anionic surfactant.
This lauryl-grade sodium dodecyl sulfate (SDS) is a popular anionic detergent for routine protein electrophoresis and cell lysis methods.
The formulation of Sodium dodecyl sulfate is a mixture of several different alkyl sulfate chain lengths (C10 to C18).

Sodium dodecyl sulfate (or sulphate) (SDS or NaDS) (C12H25SO4Na), is an anionic surfactant that is used in household products such as toothpastes, shampoos, shaving foams and bubble baths for its thickening effect and its ability to create a lather.
Sodium dodecyl sulfate has a tail of 12 carbon atoms, attached to a sulfate group, giving the molecule the amphiphilic properties required of a detergent.

Sodium dodecyl sulfate is prepared by esterification of sulfuric acid with dodecanol (lauryl alcohol, C12H25OH) followed by neutralization with sodium carbonate.
Like all detergent surfactants (including soaps), Sodium dodecyl sulfate removes oils from the skin, and can cause skin and eye irritation.

Sodium dodecyl sulfate can be converted by ethoxylation to sodium laureth sulfate (also called sodium lauryl ether sulfate; SLES), which is less harsh on the skin, probably because it is not as much of a protein denaturant as is the unethoxylated substance.
Sodium dodecyl sulfate is probably the most researched anionic surfactant compound.

Sodium dodecyl sulfate has recently found application as a surfactant in gas hydrate or methane hydrate formation reactions, increasing the rate of formation as much as 700 times.
Sodium dodecyl sulfate is an organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate.

Sodium dodecyl sulfate has a role as a detergent and a protein denaturant.
Sodium dodecyl sulfate contains a dodecyl sulfate.
Sodium dodecyl sulfate is a major component of detergent.

Sodium dodecyl sulfate is usually used in the DNA extraction process to separate DNA after protein denaturation.
Sodium dodecyl sulfate is often misread as sodium dodecyl sulfonate.
Sodium dodecyl sulfate is an anionic surfactant, and is a typical representative of sulphate-based surfactant.

Sodium dodecyl sulfate is abbreviated as SDS, and also known as AS, K12, coco alcohol sulfate, sodium lauryl sulfate and foaming agent.
The commercial products are usually white to light yellow crystalline powder.
Sodium dodecyl sulfate is non-toxic, slightly soluble in alcohol, insoluble in chloroform and ether, soluble in water, and has good anionic and nonionic complex compatibility.

Sodium dodecyl sulfate has good emulsibility, foamability, and foaming, infiltrating, decontaminating and dispersing properties.
Sodium dodecyl sulfate is abundant in foams and quickly biodegradable, and has solubility next only to fatty alcohol polyoxyethylene ether sodium sulphate (abbreviated as AES).

Sodium dodecyl sulfate is not sensitive to alkali and hard water, but its stability is inferior to general sulfonate under acidic conditions and is close to AES.
Sodium dodecyl sulfate is not favorable to exceed 95 °C upon long-term heating, and its irritation is at the middle level among surfactants, with an irritation index of 3.3 for a 10% solution, which is higher than AES and lower than sodium dodecyl benzene sulfonate (abbreviated as LAS).

Sodium dodecyl sulfate (SDS) is an ionic detergent, which contains a polar sulfate head group and a hydrophobic 12-carbon chain.
Sodium dodecyl sulfate, SDS or sodium lauryl sulfate, is an anionic surfactant.
As the name suggests, Sodium dodecyl sulfate is the sodium salt form of a 12-carbon tail attached to a polar sulfate head.

The polar headgroup gives Sodium dodecyl sulfate its amphiphilic properties, making it an effective detergent in molecular biology, cosmetics, pharmaceutical research and industrial applications.
GX5289 is supplied as a fine white powder.

Sodium dodecyl sulfate (or sulphate) (SDS or NaDS) (C12H25NaO4S), also known as sodium lauryl sulfate (SLS), is an anionic surfactant that is used in household products such as toothpastes, shampoos, shaving foams and bubble baths for its thickening effect and its ability to create a lather.

Sodium dodecyl sulfate has a tail of 12 carbon atoms, attached to a sulfate group, giving the molecule the amphiphilic properties required of a detergent.
Sodium dodecyl sulfate is prepared by sulfonation of dodecanol (lauryl alcohol, C12H25OH) followed by neutralization with sodium carbonate.

Sodium dodecyl sulfate is used in both industrially produced and home-made cosmetics.
Sodium dodecyl sulfate can be converted by ethoxylation to sodium laureth sulfate (also called sodium lauryl ether sulfate; SLES), which is less harsh on the skin, probably because it is not as much of a protein denaturant as is the unethoxylated substance.

Sodium dodecyl sulfate is probably the most researched anionic surfactant compound.
Sodium dodecyl sulfate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

Sodium dodecyl sulfate is an anionic surfactant used in many cleaning and hygiene products.
Sodium dodecyl sulfate is naturally derived from coconut and/or palm kernel oil.
Sodium dodecyl sulfate usually consisting of a mixture of sodium alkyl sulfates, mainly the lauryl.

Sodium dodecyl sulfate has a tail of 12 carbon atoms, attached to a sulfate group, giving the molecule the amphiphilic properties required of a detergent.
Sodium dodecyl sulfate is a highly effective surfactant used in any task requiring the removal of oily stains and residues.

As such Sodium dodecyl sulfate is found in high concentrations in industrial products including engine degreasers, floor cleaners, and car wash soaps.
When produced from these sources, "Sodium dodecyl sulfate" products are a mixture of various sodium alkyl sulfates with SDS being the main component.

For instance, Sodium dodecyl sulfate is a component, along with other chain-length amphiphiles, when produced from coconut oil, and is known as sodium coco sulfate (SCS).
Sodium dodecyl sulfate is available commercially in powder, pellet, and other forms (each differing in rates of dissolution), as well as in aqueous solutions of varying concentrations.

Sodium dodecyl sulfate appears as white to pale yellow paste or liquid with a mild odor.
Sodium dodecyl sulfate sinks and mixes with water.
Sodium dodecyl sulfate is an organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate.

Sodium dodecyl sulfate has a role as a detergent and a protein denaturant.
Sodium dodecyl sulfate contains a dodecyl sulfate.
Sodium dodecyl sulfate and Ammonium Lauryl Sulfate appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin.

In products, Sodium dodecyl sulfate is intended for prolonged contact with skin, concentrations should not exceed 1%.
Sodium dodecyl sulfate is an anionic surfactant naturally derived from coconut and/or palm kernel oil.
Sodium dodecyl sulfate usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.

Sodium dodecyl sulfate lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes.
Sodium dodecyl sulfate also has some microbicidal activity.

Sodium dodecyl sulfate is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 7 investigational indications.
Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is an organic compound with the formula CH3(CH2)11OSO3Na and structure H3C−(CH2)11−O−S(=O)2−O−Na+.

Sodium dodecyl sulfate is an anionic surfactant used in many cleaning and hygiene products.
Sodium dodecyl sulfate is the sodium salt of the 12-carbon organosulfate.
Sodium dodecyl sulfate's hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties that make it useful as a detergent.

Sodium dodecyl sulfate is also component of mixtures produced from inexpensive coconut and palm oils.
Sodium dodecyl sulfate is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations.

USES and APPLICATIONS of SODIUM DODECYL SULFATE:
Sodium dodecyl sulfate(151-21-3) has excellent detergency, emulsification and foaming power, can be used as detergents and textile auxiliaries, and is also used as an anionic surfactant, toothpaste foaming agent, mine fire extinguishing agents, foaming agents for fire extinguishers, emulsion polymerization emulsifiers, emulsifying and dispersing agents for medical use, shampoo and other cosmetic products, wool detergent, detergent for silky class fine fabrics and flotation agent for metal beneficiation.

Sodium dodecyl sulfate stipulates as processing aids for food industry.
Sodium dodecyl sulfate used as foaming agents; emulsifying agents; and anionic surfactants.
Sodium dodecyl sulfate is used for cakes, drinks, proteins, fruits, fruit juice, and edible oil, and so on.

Sodium dodecyl sulfate is used as surfactants, detergents, foaming agents, and wetting agents, and so on.
Sodium dodecyl sulfate is used as relatively low-level ion-pairing reagents, and is cheaper than sodium heptanesulfonate and sodium pentanesulfonate when less demanding.

Sodium dodecyl sulfate is used as raw material for modifying materials.
Sodium dodecyl sulfate is used as additives in capillary electrophoresis analysis and is generally used as molar solution.
Sodium dodecyl sulfate is also used in other analysis such as flow column analysis.

Applications of Sodium dodecyl sulfate: Cleaning and hygiene
Sodium dodecyl sulfate is mainly used in detergents for laundry with many cleaning applications.
Sodium dodecyl sulfate is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues.

For example, Sodium dodecyl sulfate is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car exterior cleaners.
Sodium dodecyl sulfate is a component in hand soap, toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.

Sodium dodecyl sulfate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Sodium dodecyl sulfate is used in the following products: washing & cleaning products, coating products, plant protection products, adhesives and sealants, fillers, putties, plasters, modelling clay, air care products, polishes and waxes and cosmetics and personal care products.

Other release to the environment of Sodium dodecyl sulfate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

Other release to the environment of Sodium dodecyl sulfate is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

Sodium dodecyl sulfate can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).
Sodium dodecyl sulfate can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

Sodium dodecyl sulfate is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, plant protection products and polymers.
Sodium dodecyl sulfate is used in the following areas: building & construction work and agriculture, forestry and fishing.

Sodium dodecyl sulfate is used for the manufacture of: .
Other release to the environment of Sodium dodecyl sulfate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Sodium dodecyl sulfate is used in the following products: cosmetics and personal care products, washing & cleaning products, air care products, biocides (e.g. disinfectants, pest control products), coating products, fillers, putties, plasters, modelling clay, polishes and waxes and polymers.

Release to the environment of Sodium dodecyl sulfate can occur from industrial use: formulation of mixtures.
Sodium dodecyl sulfate is used in the following products: polymers, laboratory chemicals, pharmaceuticals and washing & cleaning products.
Sodium dodecyl sulfate is used for the manufacture of:.

Release to the environment of Sodium dodecyl sulfate can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and for thermoplastic manufacture.

Other release to the environment of Sodium dodecyl sulfate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Release to the environment of Sodium dodecyl sulfate can occur from industrial use: manufacturing of the substance.

Sodium dodecyl sulfate is obtained in a state of powder as well as in pellet and used in Polymer Biotechnology and Biochemistry.
This review article is related to present and future uses of Sodium dodecyl sulfate in different applied fields.
The critical micelle concentration (cmc) of Sodium dodecyl sulfate changes with change in temperature and addition of electrolyte.

Sodium dodecyl sulfate causes skin and eye irritation in higher concentration but such effect decreases with decrease in concentration and widely used as cleaning agent and house hold products.
Sodium dodecyl sulfate is used in both industrially produced and home-made cosmetics.

Sodium dodecyl sulfate is widely used as a foaming agent in toothpaste, soap, shower gel, shampoo, detergent and cosmetics.
95% of personal care products and household cleaning products contain sodium lauryl sulfate.
Sodium dodecyl sulfate is an emulsifier and whipping aid that has a solubility of 1 g in 10 ml of water.

Sodium dodecyl sulfate functions as an emulsifier in egg whites.
Sodium dodecyl sulfate is used as a whipping aid in marshmallows and angel food cake mix.
Sodium dodecyl sulfate also functions to aid in dissolving fumaric acid.

Uses of Sodium dodecyl sulfate: Wetting agent, detergent, especially in the textile industry.
Sodium dodecyl sulfate is used electrophoretic separation of proteins and lipids.
Sodium dodecyl sulfate is used ingredient of toothpastes.

Sodium dodecyl sulfate has been used as a negatively charged surfactant to study its effects on filtration flux and membrane fouling during the microfiltration of the surfactant-stabilized oil emulsion
Sodium dodecyl sulfate is used as a component of plant extraction buffer, and transferring buffer for western blot

Sodium dodecyl sulfate is used as a component of 5× Laemmli sample buffer (5× LB) and 10× SDS running buffer for sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblot
Sodium dodecyl sulfate is used anionic detergent.

Sodium dodecyl sulfate has recently found application as a surfactant in gas hydrate or methane hydrate formation reactions, increasing the rate of formation as much as 700 times.
Sodium dodecyl sulfate lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes.

Sodium dodecyl sulfate is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry.
Sodium dodecyl sulfate also has some microbicidal activity.
In household products, Sodium dodecyl sulfate is used in lower concentrations with toothpastes, shampoos, and shaving foams.

Sodium dodecyl sulfate is an important component in bubble bath formulations for its thickening effect and its ability to create a lather.
Sodium dodecyl sulfate is an anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.

Sodium dodecyl sulfate has been proposed as a potentially effective topical microbicide, for intravaginal use, to inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the herpes simplex viruses, HIV, and the Semliki Forest virus.
Liquid membranes formed from Sodium dodecyl sulfate in water have been demonstrated to work as unusual particle separators.

The device acts as a reverse filter, allowing large particles to pass while capturing smaller particles.
Lauryl alcohol can be used in pure form or as a mixtures of fatty alcohols.
Sodium dodecyl sulfate is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry.

-Pharmaceutical Applications of Sodium dodecyl sulfate:
Sodium dodecyl sulfate is an anionic surfactant employed in a wide range of nonparenteral pharmaceutical formulations and cosmetics.
Sodium dodecyl sulfate is a detergent and wetting agent effective in both alkaline and acidic conditions.

In recent years Sodium dodecyl sulfate has found application in analytical electrophoretic techniques:
Sodium dodecyl sulfate polyacrylamide gel electrophoresis is one of the more widely used techniques for the analysis of proteins;
and sodium lauryl sulfate has been used to enhance the selectivity of micellar electrokinetic chromatography (MEKC).

-Biochem/physiol Actions of Sodium dodecyl sulfate:
Sodium dodecyl sulfate helps to quickly disrupt the biological membranes.
Sodium dodecyl sulfate is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids.
Sodium dodecyl sulfate can block the activity of RNase and deoxyribonuclease (DNase).

-Biochemical applications of Sodium dodecyl sulfate:
In laboratories, Sodium dodecyl sulfate is commonly used in preparing proteins for polyacrylamide gel electrophoresis (SDS-PAGE).
Sodium dodecyl sulfate works by disrupting non-covalent bonds in the proteins, thereby denaturing them, causing the molecules to lose their native shape (conformation).

Also, anions of Sodium dodecyl sulfate bind to the main peptide chain at a ratio of one SDS anion for every two amino acid residues.
This effectively imparts a negative charge on the protein that is proportional to the mass of that protein (about 1.4 g Sodium dodecyl sulfate/g protein).

This new negative charge is significantly greater than the original charge of that protein.
The electrostatic repulsion that is created by binding of Sodium dodecyl sulfate causes proteins to unfold into a rod-like shape thereby eliminating differences in shape as a factor for separation in the gel.

-Food additive uses of Sodium dodecyl sulfate:
Sodium dodecyl sulfate, appearing as its synonym sodium lauryl sulfate (SLS), is considered a generally recognized as safe (GRAS) ingredient for food use according to the USFDA (21 CFR 172.822).
Sodium dodecyl sulfate is used as an emulsifying agent and whipping aid.

As an emulsifier in or with egg whites the United States Code of Federal Regulations require that it must not exceed 1,000 parts per million (0.1%) in egg white solids or 125 parts per million (0.0125%) in frozen or liquid egg whites and as a whipping agent for the preparation of marshmallows Sodium dodecyl sulfate must not exceed 0.5% of the weight of gelatine.
Sodium dodecyl sulfate is reported to temporarily diminish perception of sweetness.

-Laboratory applications of Sodium dodecyl sulfate: Sodium dodecyl sulfate is used in cleaning procedures, and is commonly used as a component for lysing cells during RNA extraction or DNA extraction, inhibiting the activity of nucleases, enzymes that can degrade DNA, protecting the integrity of the isolated genetic material, and for denaturing proteins in preparation for electrophoresis in the Sodium dodecyl sulfate-PAGE technique.

In the case of Sodium dodecyl sulfate-PAGE, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e. causing the protein molecules to lose their native conformations and shapes.
By binding to proteins at a ratio of one Sodium dodecyl sulfate molecule per 2 amino acid residues, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio.

In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their length as opposed to both their native charge and shape.
This separation based on the size of the polypeptide chain simplifies the analysis of protein molecules.

-Pharmaceutical applications of Sodium dodecyl sulfate:
Sodium dodecyl sulfate is a widely used in the pharmaceutical field as an ionic solubilizer and emulsifier that is suitable for applications in liquid dispersions, solutions, emulsions and micro emulsions, tablets, foams and semi-solids such as creams, lotions and gels.
Additionally, Sodium dodecyl sulfate aids in tablet wettability, as well as lubrication during manufacturing.

-Miscellaneous applications of Sodium dodecyl sulfate:
Sodium dodecyl sulfate is used in an improved technique for preparing brain tissues for study by optical microscopy.
The technique was the work of Karl Deisseroth and coworkers at Stanford University, and involves infusion of the organ with an acrylamide solution to bind the macromolecules of the organ (proteins, nucleic acids, etc.), followed by thermal polymerization to form a "brain–hydrogel" (a mesh interspersed throughout the tissue to fix the macromolecules and other structures in space), and then by lipid removal using Sodium dodecyl sulfate to eliminate light scattering with minimal protein loss, rendering the tissue quasi-transparent.
Along with sodium dodecylbenzene sulfonate and Triton X-100, aqueous solutions of Sodium dodecyl sulfate are popular for dispersing or suspending nanotubes, such as carbon nanotubes.

FEATURES of SODIUM DODECYL SULFATE:
Popular anionic detergent for a variety of protein methods.
Especially useful for denaturing polyacrylamide gel electrophoresis (SDS-PAGE).
Common component of cell lysis buffers.
This lauryl-grade sodium dodecyl sulfate (SDS) is a popular anionic detergent for routine protein electrophoresis and cell lysis methods.
The formulation is a mixture of several different alkyl sulfate chain lengths (C10 to C18).

RELATED COMPOUNDS of SODIUM DODECYL SULFATE:
-Other anions
*Sodium laureth sulfate
*Sodium myreth sulfate

-Other cations
*Ammonium lauryl sulfate
*Potassium lauryl sulfate

COSMETICS INGREDIENTS FUNCTIONS OF of SODIUM DODECYL SULFATE:
*CLEANSING
*SURFACTANT - CLEANSING
*DENATURANT
*FOAMING

HIGHLIGHTS of SODIUM DODECYL SULFATE:
Popular anionic detergent for a variety of protein methods.
Especially useful for denaturing polyacrylamide gel electrophoresis (Sodium dodecyl sulfate-PAGE).
Common component of cell lysis buffers.

PRODUCTION METHODS of SODIUM DODECYL SULFATE:
Sodium dodecyl sulfate is prepared by sulfation of lauryl alcohol, followed by neutralization with sodium carbonate.

BIOCHEM/PHYSIOL ACTIONS of SODIUM DODECYL SULFATE:
Sodium dodecyl sulfate effectively binds to the positively charged and the hydrophobic residues of proteins via sulfate groups and alkyl chains.
Sodium dodecyl sulfate functions as a vital detergent in the domain of structural biology and protein folding/unfolding studies.
Sodium dodecyl sulfate can stimulate the creation of α-helices in a protein structure.
Sodium dodecyl sulfate has the ability to promote cooperative unfolding in several proteins including bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations.

PREPARATION of SODIUM DODECYL SULFATE:
Sodium dodecyl sulfate can be synthesized by reacting dodecyl alcohol with sulfur trioxide gas, followed by neutralization with sodium hydroxide.
The preparation of Sodium dodecyl sulfate involves the following steps:

The reaction takes place in a vertical reactor at 32 °C.
Nitrogen gas is introduced through the gas vents at a flow rate of 85.9 L/min.
Lauryl alcohol is added at a flow rate of 58 g/min at 82.7 kPa.

Liquid sulfur trioxide is fed into the flash evaporator at 124.1 kPa, with a flow rate of 0.9072 kg/h and a flash temperature of 100 °C.
The sulfated product is quickly cooled to 50 °C, aged for 10-20 min, then neutralized with a base in a neutralization kettle controlled at 50 °C.
The pH is adjusted to 7-8.5, and the liquid product is spray dried to obtain a solid product.

CHEMICAL PROPERTIES of SODIUM DODECYL SULFATE:
Sodium dodecyl sulfate consists of white or cream to pale yellow coloured crystals, flakes, or powder having a smooth feel, a soapy, bitter taste, and a faint odor of fatty substances.
Sodium dodecyl sulfate is easily soluble in water.

REACTIVITY PROFILE of SODIUM DODECYL SULFATE:
Sodium dodecyl sulfate is incompatible with strong oxidizers.
Sodium dodecyl sulfate is also incompatible with cationic materials and with acids with pH below 2.5.
Salts, basic, such as DODECYL SULFATE, are generally soluble in water.

The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0.
They react as bases to neutralize acids.

These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

PHYSICOCHEMICAL PROPERTIES of SODIUM DODECYL SULFATE:
The critical micelle concentration (CMC) in water at 25 °C is 8.2 mM, and the aggregation number at this concentration is usually considered to be about 62.
The micelle ionization fraction (α) is around 0.3 (or 30%).

PRODUCTION of SODIUM DODECYL SULFATE:
Dodecyl alcohol is sulfated using sulfur trioxide.
The reaction proceeds by initial formation of the pyrosulfate:
2 SO3 + ROH → ROSO2−O−SO3H
ROSO2−O−SO3H → ROSO3H + SO3
Several million tons are produced annually.
Sodium dodecyl sulfate can also be synthesized by treating lauryl alcohol with chlorosulfuric acid.
The resulting half ester of sulfuric acid is then neutralized with alkali.

PHYSICAL and CHEMICAL PROPERTIES of SODIUM DODECYL SULFATE:
CAS Number: 151-21-3
E number: E487 (thickeners, ...)
Chemical formula: C12H25NaSO4
Molar mass: 288.372 g/mol
Appearance: white or cream-colored solid
Odor: odorless
Density: 1.01 g/cm3
Melting point: 206 °C (403 °F; 479 K)

Surface tension:
CMC: 8.2 mM at 25 °C
Refractive index (nD): 1.461
Molecular Weight: 288.38 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 12
Exact Mass: 288.13712473 Da

Monoisotopic Mass: 288.13712473 Da
Topological Polar Surface Area: 74.8 Å²
Heavy Atom Count: 18
Formal Charge: 0
Complexity: 249
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Linear Formula: CH3(CH2)11OSO3Na
CAS Number: 151-21-3
Molecular Weight: 288.38
NACRES: NA.21
PubChem Substance ID: 24867284
eCl@ss: 39093306

UNSPSC Code: 12161900
EC Number: 205-788-1
MDL number: MFCD00036175
Beilstein/REAXYS Number: 3599286
Physical state: powder, flakes
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/ range: 204 - 207 °C - lit.

Initial boiling point and boiling range: No data available
Flammability (solid, gas): The substance or mixture is a flammable solid with the category
Compound Canonicalized: Yes
Upper/lower flammability or explosive limits: No data available
Flash point: 170 °C - Regulation (EC) No. 440/2008, Annex, A.9
Autoignition temperature: 310,5 °C
Decomposition temperature: No data available
pH: 9,1 at 10 g/l

Viscosity:
Viscosity, kinematic: No data available
Viscosity: Viscosity, dynamic: No data available
Water solubility: 130 g/l at 20 °C - OECD Test Guideline 105
Partition coefficient: n-octanol/water: No data available
Vapor pressure: <= 0,00 hPa at 20 °C - OECD Test Guideline 104
Density: 1,03 g/cm3 at 20 °C

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: Bulk density 0,496 g/cm3
Surface tension: 25,2 mN/m at 1g/l at 23 °C
Dissociation constant: 1,31 at 20 °C

Molecular Formula / Molecular Weight: C12H25NaO4S = 288.38
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Air Sensitive,Hygroscopic
CAS RN: 151-21-3
Reaxys Registry Number: 3599286
PubChem Substance ID: 87567907

Merck Index (14): 8636
MDL Number: MFCD00036175
Color: White
Reagent Type: Detergent (Pure)
Solubility: 10% (aq, w/v) solution must be clear, colorless to slightly yellow
Form: Powder
Product Type: Detergent

Linear Formula: CH3(CH2)11OSO3Na
CAS Number: 151-21-3
Molecular Weight: 288.38
Beilstein: 3599286
EC Number: 205-788-1
MDL number: MFCD00036175
eCl@ss: 39093306
PubChem Substance ID: 329766677
NACRES: NA.25

Assay: ≥99.0% (GC)
form: rod
mol wt average: mol wt 18,000
aggregation number: 62
loss: ≤5% loss on drying
CMC: 7-10 (lit.)
mp: 204-207 °C (lit.)
transition temp: cloud point >100 °C(lit.)
solubility: H2O: soluble 0.29 gm in 10ml, clear, colorless

solubility: H2O: 0.1 M at 20 °C, clear, colorless
anion traces
CBNumber: CB2147453
Molecular Formula: C12H26O4S.Na
Molecular Weight: 289.39
MDL Number: MFCD00036175
MOL File: 151-21-3.mol
Compound Canonicalized: Yes
Melting point: 204-207 °C (lit.)

Density: 1.03 g/mL at 20 °C
bulk density: 490-560kg/m3
FEMA: 4437 | SODIUM LAURYL SULFATE
Flash point: >100°C
storage temp.: 2-8°C
solubility: H2O: 0.1 M, clear to nearly clear, colorless to slightly yellow
form: Powder or Crystals
color: White to pale yellow
Odor: Slight fatty odour

PH Range: 7.2
PH: 6-9 (10g/l, H2O, 20℃)
biological source: synthetic (oragnic)
Water Solubility: ca. 150 g/L (20 ºC)
λmax: λ: 260 nm Amax: 0.3
λmax: λ: 280 nm Amax: 0.2
Merck: 14,8636
BRN: 3599286
InChIKey: DBMJMQXJHONAFJ-UHFFFAOYSA-M

LogP: 1.600
Substances Added to Food (formerly EAFUS): SODIUM LAURYL SULFATE
CAS DataBase Reference: 151-21-3(CAS DataBase Reference)
FDA UNII: 368GB5141J
EPA Substance Registry System: Sodium lauryl sulfate (151-21-3)
Absorption: ≤0.1 at 280nm in water at 30mg/mL
UNSPSC Code: 41116107
NACRES: NC.01
Compound Canonicalized: Yes

FIRST AID MEASURES of SODIUM DODECYL SULFATE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of SODIUM DODECYL SULFATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of SODIUM DODECYL SULFATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM DODECYL SULFATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SODIUM DODECYL SULFATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of SODIUM DODECYL SULFATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available