SODIUM ETHYL P-HYDROXYBENZOATE

Sodium Ethyl p-Hydroxybenzoate is the sodium salt of ethyl p-hydroxybenzoate and is used as an antimicrobial preservative in compatible acidic to neutral formulations where improved water solubility is desired.
Sodium Ethyl p-Hydroxybenzoate is associated with paraben-type preservation chemistry, and Sodium Ethyl p-Hydroxybenzoate is valued for antifungal preservation and for easier incorporation into aqueous systems compared with the non-salt ester form.
Sodium Ethyl p-Hydroxybenzoate must be used according to local regulations because permitted preservative types and concentration limits vary by region and product category, and Sodium Ethyl p-Hydroxybenzoate should be incorporated with attention to pH, ionic strength, and preservative system compatibility.

CAS Number: 35285-69-9 (commonly associated; grade dependent)
EC Number: 252-526-5 (commonly associated; grade dependent)
Molecular Formula: C9H9NaO3
Molecular Weight: 188.16 g/mol

Synonyms: Sodium Ethyl p-Hydroxybenzoate, Sodium Ethylparaben, Ethylparaben Sodium Salt, Sodium 4-Hydroxybenzoate Ethyl Ester (salt form), Sodium Ethyl p-Hydroxybenzoate Preservative, Sodium Ethyl p-Hydroxybenzoate Food Additive (market dependent), Sodium Ethyl p-Hydroxybenzoate Cosmetic Preservative, Sodium Ethyl Parahydroxybenzoate, Sodium 4-Hydroxybenzoate Ethyl Ester, Sodium Ethylparaben Preservative, Ethylparaben Sodium, Sodium Ethyl Hydroxybenzoate, Sodium Ethyl p-Hydroxybenzoate, Sodium Ethyl p-Hydroxybenzoate, Sodium Ethyl para-Hydroxybenzoate, Sodium Ethyl para-Hydroxy Benzoate, Sodium Ethyl 4-Hydroxybenzoate, Sodium 4-Hydroxybenzoic Acid Ethyl Ester, Sodium Ethylparaben, Sodium Ethyl Paraben, Ethylparaben Sodium, Ethyl Paraben Sodium, Sodium p-Hydroxybenzoic Acid Ethyl Ester, Sodium para-Hydroxybenzoic Acid Ethyl Ester, Sodium 4-Hydroxybenzoic Acid Ethyl Ester Salt, Sodium Salt of Ethyl p-Hydroxybenzoate, Sodium Salt of Ethylparaben, Sodium Salt of Ethyl Paraben, Sodium p-Hydroxybenzoate Ethyl Ester, Sodium para-Hydroxybenzoate Ethyl Ester, p-Hydroxybenzoic Acid Ethyl Ester Sodium Salt, para-Hydroxybenzoic Acid Ethyl Ester Sodium Salt, 4-Hydroxybenzoic Acid Ethyl Ester Sodium Salt, Sodium 4-(Ethoxycarbonyl)phenolate, Sodium p-Carbethoxyphenolate, Sodium para-Carbethoxyphenolate, Sodium Ethyl 4-Hydroxy Benzoate, Sodium Ethyl p-Hydroxybenzoate Preservative Grade, Sodium Ethylparaben Preservative, Sodium Ethyl Paraben Preservative, Sodium Ethylparaben Food Grade, Sodium Ethyl Paraben Food Grade, Sodium Ethylparaben Pharmaceutical Grade, Sodium Ethyl Paraben Pharmaceutical Grade, Sodium Ethylparaben Cosmetic Grade, Sodium Ethyl Paraben Cosmetic Grade, Sodium Ethylparaben Technical Grade, Sodium Ethyl Paraben Technical Grade, Sodium Ethylparaben USP, Sodium Ethyl Paraben USP, Sodium Ethylparaben BP, Sodium Ethyl Paraben BP, Sodium Ethylparaben EP, Sodium Ethyl Paraben EP, Sodium Ethylparaben NF, Sodium Ethyl Paraben NF, Sodium Ethylparaben FCC, Sodium Ethyl Paraben FCC, Sodium Ethylparaben Reagent, Sodium Ethyl Paraben Reagent, Sodium Ethylparaben Antimicrobial, Sodium Ethyl Paraben Antimicrobial, Sodium Ethylparaben Antifungal, Sodium Ethyl Paraben Antifungal, Sodium Ethylparaben Sodium Salt, Sodium Ethyl Paraben Sodium Salt, Ethyl p-Hydroxybenzoate Sodium Salt, Ethyl para-Hydroxybenzoate Sodium Salt, Ethyl 4-Hydroxybenzoate Sodium Salt, Sodium p-Hydroxybenzoate Ethyl, Sodium para-Hydroxybenzoate Ethyl, Sodium 4-Hydroxybenzoate Ethyl, Sodium Ethyl p-Hydroxy Benzoate, Sodium Ethyl para Hydroxybenzoate, Sodium Ethyl 4 Hydroxybenzoate, Sodium p-Hydroxybenzoic Acid Ethyl Ester Salt, Sodium para-Hydroxybenzoic Acid Ethyl Ester Salt, Sodium 4-Hydroxybenzoic Acid Ethyl Salt, Ethylparaben Sodium Salt, Ethyl Paraben Sodium Salt, Sodium Ethyl p-Hydroxybenzoate Preservative, Sodium Ethyl p-Hydroxybenzoate Antimicrobial

APPLICATIONS

Sodium Ethyl p-Hydroxybenzoate is used in water-based cosmetics and personal care products to inhibit yeast and mold growth and to support overall preservation.
Sodium Ethyl p-Hydroxybenzoate is incorporated into lotions and creams where improved water solubility supports easier manufacturing.
Sodium Ethyl p-Hydroxybenzoate is used in facial products where preservative robustness is required and regulations allow.

Sodium Ethyl p-Hydroxybenzoate is used in shampoos and conditioners as part of preservative systems to prevent microbial contamination in aqueous surfactant products.
Sodium Ethyl p-Hydroxybenzoate is incorporated into rinse-off products where pH and ionic strength are managed for effective preservation.
Sodium Ethyl p-Hydroxybenzoate is used in liquid soaps and shower gels to support fungal control in compatible formulations.

Sodium Ethyl p-Hydroxybenzoate is used in personal care wipes to inhibit microbial growth in wet wipe liquids and to protect products during storage.
Sodium Ethyl p-Hydroxybenzoate is incorporated into cleansing wipes where preservative efficacy must be validated with challenge testing.
Sodium Ethyl p-Hydroxybenzoate is used in rinse-free products where microbial control is critical due to repeated consumer exposure.

Sodium Ethyl p-Hydroxybenzoate is used in pharmaceutical syrups and oral liquids in some contexts as a preservative where allowed and where pH supports activity.
Sodium Ethyl p-Hydroxybenzoate is incorporated into topical solutions and gels where antimicrobial preservation is required.
Sodium Ethyl p-Hydroxybenzoate is used in creams and ointments to protect against contamination during storage and use.

Sodium Ethyl p-Hydroxybenzoate is used in compounded formulations where preservative selection depends on solubility, compatibility, and regulatory constraints.
Sodium Ethyl p-Hydroxybenzoate is incorporated into medical wash products to maintain microbiological quality in water-based systems.
Sodium Ethyl p-Hydroxybenzoate is used in specialty topical formulations where preservative performance must be confirmed by testing.

Sodium Ethyl p-Hydroxybenzoate is used in industrial water-based products such as polishes and specialty formulations to prevent microbial spoilage.
Sodium Ethyl p-Hydroxybenzoate is incorporated into waterborne products where long shelf life and repeated exposure require robust preservation.
Sodium Ethyl p-Hydroxybenzoate is used in laboratory reagents and buffers in niche cases where preservative function is desired and compatibility is confirmed.

Sodium Ethyl p-Hydroxybenzoate is used in preservative blends with other parabens or alternative preservatives to broaden spectrum and improve challenge test results.
Sodium Ethyl p-Hydroxybenzoate is incorporated into multi-preservative systems where solubility and pH are optimized for stable efficacy.
Sodium Ethyl p-Hydroxybenzoate is valued because Sodium Ethyl p-Hydroxybenzoate provides paraben-type antifungal preservation with improved aqueous handling when regulatory requirements and formulation conditions are satisfied.

DESCRIPTION

Sodium Ethyl p-Hydroxybenzoate is the sodium salt form related to ethylparaben chemistry, and Sodium Ethyl p-Hydroxybenzoate is typically supplied as a white crystalline powder.
Sodium Ethyl p-Hydroxybenzoate offers higher water solubility than the neutral ester form, but Sodium Ethyl p-Hydroxybenzoate solubility and stability still depend on pH and ionic strength.
Sodium Ethyl p-Hydroxybenzoate preservative efficacy depends on conversion to the active undissociated form in the formulation environment, so pH management is important for performance.

Sodium Ethyl p-Hydroxybenzoate is often used with other preservatives to broaden antimicrobial spectrum and to improve robustness against bacteria.
Sodium Ethyl p-Hydroxybenzoate can interact with formulation components, and high electrolyte levels can influence solubility and can impact emulsions and surfactant systems.
Sodium Ethyl p-Hydroxybenzoate is regulated, and maximum allowed concentrations and permitted product categories vary by region, so compliance checks are required.

Sodium Ethyl p-Hydroxybenzoate should be stored in tightly closed containers in a cool, dry place protected from moisture and contamination.
Sodium Ethyl p-Hydroxybenzoate dust can irritate eyes and respiratory tract, so dust control and appropriate PPE are recommended during handling.
Sodium Ethyl p-Hydroxybenzoate should be used according to supplier specifications, safety documentation, and applicable cosmetic, pharmaceutical, or food additive regulations.

PROPERTIES

Chemical Formula: C9H9NaO3
Molecular Weight: 188.16 g/mol
Common Name: Sodium Ethyl p-Hydroxybenzoate
Chemical Type: Preservative salt related to paraben chemistry
Appearance: White crystalline powder
Odor: Odorless to slight characteristic odor
Solubility: Soluble in water to improved extent vs ethylparaben; solubility depends on pH and ionic strength
Melting / Decomposition: Decomposes at elevated temperature (grade dependent)
pH Use Range: Most effective in mildly acidic to neutral systems (formulation dependent)
Preservative Activity: Strong antifungal; moderate antibacterial; often used in blends
Stability: Stable under recommended storage; hydrolyzes under strong alkaline conditions
Regulatory Status: Use limits and allowed categories vary by market; compliance required
Storage Temperature: 10–25°C, dry, tightly closed
Shelf Life: Typically 24–60 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during weighing and powder transfer.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a large amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses, and use dust protection as needed.
Avoid generating dust and avoid inhalation of fine powder.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use local exhaust or general ventilation where dust may be generated.
Maintain good airflow during weighing, charging, and blending operations.
Minimize airborne particulate accumulation in enclosed areas.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain free-flowing behavior.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Sweep up spilled material and avoid dust generation.
Collect into suitable containers for reuse or disposal according to local regulations.
Clean residues with wet wiping if needed to reduce airborne dust.

Handling Precautions:
Optimize pH and formulation design because sodium paraben salts can shift between salt and active forms, influencing efficacy and solubility.
Confirm regional regulatory limits and allowed product categories for Sodium Ethyl p-Hydroxybenzoate before formulation and labeling.
Validate preservative efficacy with challenge testing because preservative performance depends strongly on formulation composition, pH, and packaging.