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SODIUM ETHYL PARABEN

Sodium Ethyl Paraben is used food industry (dairy products, pickles, beverage, textile industry (dry goods, cotton yarn, chemical fibers), as well as antiseptics in cosmetics, feedstuffs, daily-chemicals.
Sodium Ethyl Paraben is widely used in pharmaceutical, food, cosmetics, feed, manufactured goods for daily use, and other industries.

CAS Registry Number: 35285-68-8
EC / EINECS Number: 252-487-6
Molecular Formula: C₉H₉NaO₃
Molecular Weight: ~188.16 g/mol

SYNONYMS:
Sodium ethylparaben,Sodium 4-(ethoxycarbonyl)phenolate,ethylparaben sodium,sodium,4-ethoxycarbonylphenolate,Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt,Sodium Ethyl Parahydroxybenzoate,Ethylparaben, sodium salt,4-Hydroxybenzoic acid-ethyl ester sodium,Z0D00IVA10,4-Hydroxybenzoic acid, ethyl ester, sodium salt,MFCD00016475,SODIUM ETHYL 4-HYDROXYBENZOATE,Ethylparaben sodium (NF),ETHYLPARABEN SODIUM [NF],E 215,Sodium 4-ethoxycarbonylphenoxide,EINECS 252-487-6,Ethyl p-hydroxybenzoate, sodium salt,UNII-Z0D00IVA10, sodium ethyl hydroxybenzoate, SCHEMBL475793,orb2942396,DTXSID0042402,odium 4-(ethoxycarbonyl)phenolate,SODIUM ETHYLHYDROXYBENZOATE,QYNMSPKSYXPZHG-UHFFFAOYSA-M,ETHYL HYDROXYBENZOATE SODIUM,ETHYL 4-HYDROXYBENZOATE SODIUM,AKOS006229160,ETHYLPARABEN, SODIUM SALT [II],FE70225,HY-W099118,sodium 4-(ethoxycarbonyl)benzen-1-olate,E215,CS-0151760,E-215,NS00088684,SODIUM ETHYL HYDROXYBENZOATE [MART.],D10929,E78650,F319780,Q3963917,SODIUM ETHYL PARAHYDROXYBENZOATE [EP MONOGRAPH],BENZOIC ACID, p-HYDROXY-, ETHYL ESTER, SODIUM DERIV.,benzoic acid, 4-hydroxy-, ethyl ester, sodium salt,benzoic acid, p-hydroxy-, ethyl ester, sodium deriv.,ethyl p-hydroxybenzoate, sodium salt,ethylparaben sodium,ethylparaben, sodium salt,4-hydroxybenzoic acid, ethyl ester, sodium salt,sodium 4-ethoxycarbonyl phenoxide,sodium 4-ethoxycarbonylphenoxide,sodium ethyl 4-hydroxybenzoate,sodium ethyl p-hydroxybenzoate,sodium ethyl paraben,sodium,4-ethoxycarbonylphenolate,Sodium ethylparaben,Sodium 4-(ethoxycarbonyl)phenolate,Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt (1:1),35285-68-8,EINECS 252-487-6,Ethyl p-hydroxybenzoate, sodium salt,UNII-Z0D00IVA10,Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt, benzoic acid, p-hydroxy-, ethyl ester sodium deriv., ethyl p-hydroxybenzoate sodium salt, ethylparaben sodium, ethylparaben, sodium salt, 4-hydroxybenzoic acid, ethyl ester, sodium salt, sodium 4-ethoxycarbonyl phenoxide, sodium 4-ethoxycarbonylphenoxide, sodium ethyl 4-hydroxybenzoate, sodium ethyl p-hydroxybenzoate, sodium ethyl paraben, sodium,4-ethoxycarbonylphenolate

Sodium Ethyl Paraben is a water-soluble antiseptic mainly used as a safe, high efficiency, broad-spectrum antibiotic for cosmetics.
Sodium Ethyl Paraben is the sodium salt of Ethylparaben, a member of the paraben family.

Sodium Ethyl Paraben is a widely used preservative in cosmetics and personal care products, known for its antimicrobial properties that help extend product shelf life.
Commonly, Sodium Ethyl Paraben is added to creams, lotions, shampoos, conditioners, and makeup products.

In its raw form, Sodium Ethyl Paraben appears as a white, crystalline powder or granules that is highly soluble in water - making it easier to
incorporate into aqueous formulations.
Sodium Ethyl Paraben is quite cost-effective as it provides reliable preservation at low concentrations.

The chemical formula of Sodium Ethyl Paraben is C9H9NaO3.
Sodium Ethyl Paraben is a non-toxic, odorless, non-irritating, non-allergic white crystalline powder, easily soluble in water.
Sodium Ethyl Paraben is a water-soluble antiseptic mainly used as a safe, high efficiency, broad-spectrum antibiotic for cosmetics.

Sodium Ethyl Paraben is in the paraben family of preservatives used by the food, pharmaceutical, and personal care product industries.
Sodium Ethyl Paraben is the paraben Salts of Ethylparaben.

Sodium Ethyl Paraben exhibits the same antimicrobial activity as regular Parabens.
Sodium Ethyl Paraben is a water-soluble antiseptics, mainly features as a safe, high efficiency, broad- spectrum antibiotic and widely used in Pharmacy industry sterilization).

USES and APPLICATIONS of SODIUM ETHYL PARABEN:
Preservative / Antimicrobial: Sodium Ethyl Paraben prevents growth of yeast, mold, and bacteria in formulations.
Cosmetics & Personal Care: Sodium Ethyl Paraben is used in creams, lotions, shampoos, conditioners, serums, makeup, and toiletries to extend shelf life.

Pharmaceutical Products: Sodium Ethyl Paraben is used preservative in topical and some aqueous pharmaceutical formulations.
Food & Feed (in some jurisdictions): Sodium Ethyl Paraben is historically used as an antimicrobial/antifungal (E number E215 for the sodium salt).

Industrial / Textile Uses of Sodium Ethyl Paraben: Antiseptic properties applied in certain processing contexts.
Mechanism: Sodium Ethyl Paraben inhibits microbial proliferation by disrupting cell membrane function (typical of parabens).
Sodium Ethyl Paraben is used food industry (dairy products, pickles, beverage, textile industry (dry goods, cotton yarn, chemical fibers), as well as antiseptics in cosmetics, feedstuffs, daily-chemicals.

Sodium Ethyl Paraben is widely used in pharmaceutical, food, cosmetics, feed, manufactured goods for daily use, and other industries.
Sodium Ethyl Paraben (Sodium ethyl 4-hydroxybenzoate) acts as a water soluble antiseptic usually employed as safe for cosmetics.
Sodium Ethyl Paraben is in the paraben family of preservatives used by the food, pharmaceutical, and personal care product industries.

WHAT IS SODIUM ETHYL PARABEN USED FOR?
Sodium Ethyl Paraben is primarily used as a preservative and antimicrobial agent in cosmetics and personal care.
Sodium Ethyl Paraben effectively inhibits bacteria, yeast, and mold, extending the shelf life of formulations.

Sodium Ethyl Paraben is a versatile ingredient that can be found in products like creams, serums, conditioners, and shampoos - maintaining their integrity over time.
Sodium Ethyl Paraben is also used in makeup, including foundations and mascaras, to ensure product stability during storage and use.
Its water solubility makes Sodium Ethyl Paraben ideal for aqueous formulations, and its effectiveness at low concentrations enhances formulation efficiency.

ORIGIN of SODIUM ETHYL PARABEN:
Sodium Ethyl Paraben is synthesized by neutralizing Ethylparaben with a sodium hydroxide solution, converting the ester into its water-soluble sodium salt form.
This enhances Sodium Ethyl Paraben's solubility in aqueous formulations.

WHAT DOES SODIUM ETHYL PARABEN DO IN A FORMULATION?
*ANTIMICROBIAL
*PRESERVATIVE

SAFETY PROFILE of SODIUM ETHYL PARABEN:
Sodium Ethyl Paraben is recognized as a safe ingredient up to the concentrations of 0.4%.
Studies show low acute toxicity and minimal risk of skin irritation or sensitization.
However, parabens, including Sodium Ethyl Paraben, have faced scrutiny for potential endocrine-disrupting effects due to their weak estrogenic activity.
Sodium Ethyl Paraben is best to perform a patch test prior to full application.

ALTERNATIVES of SODIUM ETHYL PARABEN:
*PHENOXYETHANOL
*POTASSIUM SORBATE
*BENZYL ALCOHOL

FUNCTION(S) of SODIUM ETHYL PARABEN IN COSMETIC PRODUCTS
PRESERVATIVE
Sodium Ethyl Paraben protects cosmetic products from microbial spoilage

FUNCTION IN FORMULATIONS of SODIUM ETHYL PARABEN:
*Preservative:
Sodium Ethyl Paraben controls microbial contamination, extends product shelf life.

*Antimicrobial Agent:
Effective against fungi, yeast, and some bacteria.
Typical inclusion levels in cosmetics are low (e.g., 0.1–0.3%) based on finished product weight.

KEY CHARACTERISTICS of SODIUM ETHYL PARABEN:
Benefits in Formulation:
Highly effective antimicrobial preservative at low inclusion levels.
Water-soluble due to sodium salt form.
Broad spectrum vs. fungi and yeast.

SAFETY NOTES of SODIUM ETHYL PARABEN:
Generally well tolerated at regulated concentrations.
Mild irritant/allergen potential in sensitive subjects.
Parabens face scrutiny for estrogen-mimicking activity, but acceptable safety margins exist according to regulatory assessments.

CHEMICAL FAMILY & CLASSIFICATION of SODIUM ETHYL PARABEN:
Chemical Class: Paraben (alkyl p-hydroxybenzoate) derivative; sodium salt of an ester.
Functional Group: Phenolic ester (p-hydroxybenzoate moiety) with sodium counter-ion.
Parabens are a family of esters of p-hydroxybenzoic acid, where the sodium salt form enhances water solubility.

PHYSICAL and CHEMICAL PROPERTIES of SODIUM ETHYL PARABEN:
Molecular Weight:188.16 g/mol
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:188.04493843 Da
Monoisotopic Mass:188.04493843 Da
Topological Polar Surface Area:49.4 Å²
Heavy Atom Count:13
Formal Charge:0
Complexity:153
Isotope Atom Count:0

Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Melting Point:230-240°C
pH:6-8
Solubility:Highly soluble in water
ECHA EINECS - REACH Pre-Reg:252-487-6
FDA UNII:Z0D00IVA10

Nikkaji Web:J42.047F
Molecular Weight:188.15809928
Formula:C9 H9 Na O3
Assay:95.00 to 100.00
Food Chemicals Codex Listed:No
Soluble in:water, 2.656e+005 mg/L @ 25 °C (est)
Appearance:White to off-white crystalline powder or granules.
Odor:Characteristic, mild.
Molecular Formula:C₉H₉NaO₃.

Molecular Weight:~188.16 g/mol.
Solubility:Highly soluble in water (cold water up to tens of g/L).
pH (aqueous solution):Typically around 9.5–10.5 for a neutralized solution.
Melting / Decomposition:Powder form stable; specific melting range often reported ~230–240°C (varies with purity/source).
Boiling Point:~297–298°C (reported for related sodium salt).
Physical State:Solid at ambient conditions (crystalline).
Log P / Partition:Moderate (predicted ~2.0); not highly lipophilic
Preferred Name:Sodium Ethyl Paraben

IUPAC Name:Sodium 4-(ethoxycarbonyl)phenoxide
Common/Systematic Names:Sodium ethyl p-hydroxybenzoate; Ethylparaben sodium salt; Ethyl p-hydroxybenzoate sodium salt; Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt.
CAS Registry Number:35285-68-8
EC / EINECS Number:252-487-6
PubChem CID (entry):23681179
Molecular Formula:C₉H₉NaO₃
Molecular Weight:~188.16 g/mol

FIRST AID MEASURES of SODIUM ETHYL PARABEN:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of SODIUM ETHYL PARABEN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of SODIUM ETHYL PARABEN:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM ETHYL PARABEN:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SODIUM ETHYL PARABEN:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of SODIUM ETHYL PARABEN:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available