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SODIUM FLUORIDE

CAS NUMBER: 7681-49-4

EC NUMBER: 231-667-8

MOLECULAR FORMULA: NaF

MOLECULAR WEIGHT: 41.98817

IUPAC NAME: sodium;fluoride

Sodium Fluoride (NaF) is an inorganic compound with the formula NaF. 
Sodium Fluoride is used in trace amounts in the fluoridation of drinking water, in toothpaste, in metallurgy, and as a flux. 

Sodium Fluoride is a colorless or white solid that is readily soluble in water. 
Sodium Fluoride is a common source of fluoride in the production of pharmaceuticals and is used to prevent dental cavities.

Sodium Fluoride is a colorless crystalline solid or white powder, or the solid dissolved in a liquid. 
Sodium Fluoride is soluble in water. 

Sodium Fluoride is noncombustible. 
Sodium Fluoride is corrosive to aluminum. 

Sodium Fluoride is used as an insecticide. 
Sodium Fluoride is also used to fluorinate water supplies, as a wood preservative, in cleaning compounds, manufacture of glass, and for many other uses.

Sodium Fluoride is an inorganic salt of fluoride used topically or in municipal water fluoridation systems to prevent dental caries. 
Fluoride appears to bind to calcium ions in the hydroxyapatite of surface tooth enamel, preventing corrosion of tooth enamel by acids. 
This agent may also inhibit acid production by commensal oral bacteria.

Sodium Fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. 
Sodium Fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated drinking water showed less tooth decay than those without fluoridated water. 

USES: 
Dental Caries:
Fluoride salts are often added to municipal drinking water (as well as to certain food products in some countries) for the purpose of maintaining dental health. 
The fluoride enhances the strength of teeth by the formation of fluorapatite, a naturally occurring component of tooth enamel.
Although sodium fluoride is used to fluoridate water and is the standard by which other water-fluoridation compounds are gauged, hexafluorosilicic acid (H2SiF6) and its salt sodium hexafluorosilicate (Na2SiF6) are more commonly used additives

Osteoporosis:
Fluoride supplementation has been extensively studied for the treatment of postmenopausal osteoporosis. 
This supplementation does not appear to be effective; even though sodium fluoride increases bone density, it does not decrease the risk of fractures.

Chemistry:
Sodium Fluoride has a variety of specialty chemical applications in synthesis and extractive metallurgy. 
Sodium Fluoride reacts with electrophilic chlorides including acyl chlorides, sulfur chlorides, and phosphorus chloride.
Like other fluorides, Sodium Fluoride finds use in desilylation in organic synthesis. Sodium fluoride can be used to produce fluorocarbons via the Finkelstein reaction; this process has the advantage of being simple to perform on a small scale but is rarely used on an industrial scale due to the existence of more effective techniques (e.g. Electrofluorination, Fowler process).

Production:
Sodium Fluoride is prepared by neutralizing hydrofluoric acid or hexafluorosilicic acid (H2SiF6), both byproducts of the reaction of fluorapatite (Ca5(PO4)3F) from phosphate rock during the production of superphosphate fertilizer. 
Neutralizing agents include sodium hydroxide and sodium carbonate. 
Alcohols are sometimes used to precipitate the NaF:
HF + NaOH → NaF + H2O

From solutions containing HF, sodium fluoride precipitates as the bifluoride salt sodium bifluoride (NaHF2). 
Heating the latter releases HF and gives NaF.
HF + NaF ⇌ NaHF2

Sodium Fluoride solutions are used with hard water insoluble compounds of calcium and magnesium fluoride can form. 
Sodium Fluoride is a dry chemical used in fluoridation of drinking water, it should be manually weighed and added to the mixing tank.

Sodium Fluoride has bactericidal properties but it is too toxic to be used as a wound antiseptic.
Sodium Fluoride makes teeth more resistant to decay and bacteria that cause cavities. 
This medication is used to prevent cavities.

Sodium Fluoride is used as an insecticide.
Used in the fluoridation of public water.
The monosodium salt of Sodium Fluoride L-glutamic acid; used in the treatment of encephalopathies associated with liver diseases.

What is Sodium Fluoride Used For?
Sodium Fluoride is used for cavity prevention. 
This makes the teeth healthier and more resistant to acid and bacteria causing decay. 
Used for the treatment of osteoporosis and otospongiosis in adults, its use is controversial and further studies are expected.

Where Does Fluoride Come From?
Fluoride is a mineral that occurs in all natural water bodies worldwide. 
This dissolves into the groundwater like iron and calcium, which we rely on for our drinking water.


PHYSICAL PROPERTIES: 

-Molecular Weight: 41.9881724        

-Exact Mass: 41.98817244    

-Monoisotopic Mass: 41.98817244    

-Topological Polar Surface Area: 0 Ų    

-Physical Description: Odorless, white powder or colorless crystals

-Color: Colorless or White

-Form: Solid

-Odor: Odorless

-Taste: Salty

-Boiling Point: 1704 °C

-Melting Point: 993 °C

-Solubility: 4g/100mL

-Density: 2.8 g/cm³

-Vapor Pressure: 1 mm Hg

-Chemical Classes: Other Classes -> Fluorides, Inorganic


Sodium Fluoride is scientifically proven that the correct amount of fluoride in water and use of fluoride-containing toothpastes and mouth rinses have a significant benefit on oral health and help to reduce tooth decay.
Sodium Fluoride helps promote remineralisation of the tooth surface.

Sodium Fluoride is a colorless crystalline solid or white powder that is soluble in liquids. 
Adding Sodium Fluoride in toothpaste or sodium fluoride in mouthwash has a role in preventing tooth decay. 

This is because fluoride has the ability to bind with calcium ions in the hydroxyapatite of the enamel surface, preventing enamel erosion by acids. 
Sodium Fluoride may also inhibit acid production by oral bacteria.


CHEMICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 0    

-Hydrogen Bond Acceptor Count: 1    

-Rotatable Bond Count: 0

-Heavy Atom Count: 2    

-Formal Charge: 0    

-Complexity: 2    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 2    

-Compound Is Canonicalized: Yes


In its free elemental form, Sodium Fluoride is a trace mineral (like iodine) called fluorine. 
Sodium Fluoride can be found in both freshwater and seawater, in foods (eg, fish, tea) and in the bones of animals, including humans. 

In nature, Sodium Fluoride is found only in compounds, such as fluorite (calcium fluoride) ores in soil and rocks. 
To form Sodium Fluoride, hydrogen fluoride (derived from fluorine) is neutralized by sodium hydroxide from brine and dried to a powder.

Sodium Fluoride is one of the three main types of fluoride used in oral health products to help prevent tooth decay, alongside sodium monofluorophosphate and stannous fluoride.
Not only present in a certain concentration in tap water, Sodium Fluoride in toothpaste or sodium fluoride in mouthwash will help strengthen the role of preventing tooth decay safely and effectively when formulated. 

Correct formula, use as directed. 
Sodium Fluoride molecules help prevent tooth decay and help remineralize tooth enamel, penetrating the enamel to rebuild eroded sites.
Therefore, in many countries, dentists often trust and recommend people to use toothpaste with added Sodium Fluoride. 

Applications: 
-Mouth and dental health

-Osteoporosis supplement

-Medical imaging

-Organic synthesis in chemistry

-Fluorocarbon production


Sodium Fluoride is an inorganic compound with the formula NaF. 
Sodium Fluoride is used in trace amounts of fluoridation of drinking water, toothpaste, metallurgy, flux, pesticides and rat poisons. 

Sodium Fluoride is a colorless or white solid that is easily soluble in water. 
Sodium Fluoride is a common source of fluoride in pharmaceutical manufacturing and is used to prevent dental caries.

Sodium Fluoride has a variety of specialty chemical applications in synthesis and extractive metallurgy. 
Reacts with electrophilic chlorides, including acid chloride, sulfur chloride and phosphorus chloride. 

Like other fluorides, Sodium Fluoride finds use in desililation in organic synthesis.
Sodium Fluoride is used as a cleaning agent.


SYNONYMS: 

sodium fluoride
7681-49-4
Zymafluor
Sodium fluoride (NaF)
Fluoride, sodium
Florocid
Pediaflor
Pergantene
Ossin
sodium;fluoride
Sodium flouride
duraphat
Antibulit
Floridine
Fluonatril
Fluoraday
Fluorident
Fluorigard
Fluorinse
Flurexal
Karidium
Koreberon
Liquiflur
Villiaumite
Xaridium
Fluorol
Flursol
Luride
Ossalin
Flura
Flux
Roach salt
Flura Drops
Neutra Care
Minute-Gel
Osteopor-F
T-Fluoride
Fungol B
Les-Cav
Sodium monofluoride
Sodium hydrofluoride
Alcoa sodium fluoride
Sodium fluorure
Fluorid sodny
Sodium fluoride [ISO]
Fluorure de sodium
Sodium fluoride (Na2F2)
Sodium fluoride cyclic dimer
Dentalfluoro
Natrum fluoratum
Chemifluor
Flozenges
Fluorineed
Fluoritab
Fluorocid
Flurcare
Gelution
Iradicav
Karigel
Lemoflur
Nufluor
Pedident
Pennwhite
Predent
Rafluor
Studafluor
Nafeen
Credo
Gleem
Rescue squad
Kari-rinse
NaFpak
Super-dent
Thera-flur
Cavi-trol
Flura-gel
Flura-loz
Na frinse
Natrium fluoride
Point two
Luride lozi-tabs
Phos-Flur
Stay-Flo
Fluor-O-kote
Thera-flur-N
Luride SF
Luride-SF
Lea-Cov
SO-Flo
Trisodium trifluoride
Duofluorid
Apoflux
Ethedent
Fludent
Fluorure de sodium
Fluorure de sodium
Prevident 5000 Plus
Natrii fluoridum
NaFril Ret
Fluorinse (TN)
En-De-Kay
Pediaflor; Zymafluor
Sodium fluoride, solid
Neutral Sodium Fluoride
EC 231-667-8
NATRII FLUORIDUM
Sodium fluoride
 

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